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Article: [Research advances on the construction of artificial dermal scaffolds based on biomaterials].

Chen, J Q / Zhu, S H

Zhonghua shao shang yu chuang mian xiu fu za zhi

2022 Volume 38, Issue 10, Page(s) 968–972

Abstract: In the field of wound repair, scarless healing and complete reconstruction of skin function are major challenges in clinical and basic research. At present, a variety of artificial dermal scaffolds have been used in the clinical repair of wounds to ... ...

Abstract	In the field of wound repair, scarless healing and complete reconstruction of skin function are major challenges in clinical and basic research. At present, a variety of artificial dermal scaffolds have been used in the clinical repair of wounds to overcome the problems such as skin structural disorders caused by tissue defects. The biomaterials used to make artificial dermal scaffolds in skin and tissue engineering research mainly include three categories: natural biomaterials, biosynthetic materials, and organic polymer materials. This review summarizes the biocompatibility, bioactivity, and degradability of biomaterials and their effects on wound healing, and provides an overview of artificial dermal scaffold construction strategies based on biomaterials, wound healing cells, and associated cytokines.
MeSH term(s)	Biocompatible Materials/chemistry ; Tissue Scaffolds/chemistry ; Skin, Artificial ; Skin ; Polymers/chemistry ; Cytokines
Chemical Substances	Biocompatible Materials ; Polymers ; Cytokines
Language	Chinese
Publishing date	2022-09-28
Publishing country	China
Document type	Review ; English Abstract ; Journal Article
ISSN	2097-1109
ISSN	2097-1109
DOI	10.3760/cma.j.cn501225-20220606-00221
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Article: [Effects of metabolic surgery on islet function in Asian patients with type 2 diabetes].

Cao, Y Q / Tang, H B / Zhu, S H / Zhu, L Y

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

2022 Volume 25, Issue 10, Page(s) 892–898

Abstract: Type 2 diabetes is a high-profile global public health problem, particularly in Asia. The young age of onset, low body mass index, and early appearance of pancreatic islet dysfunction are characteristics of Asian patients with T2DM. Metabolic surgery has ...

Abstract	Type 2 diabetes is a high-profile global public health problem, particularly in Asia. The young age of onset, low body mass index, and early appearance of pancreatic islet dysfunction are characteristics of Asian patients with T2DM. Metabolic surgery has become the standard treatment for T2DM patients and can significantly improve T2DM through a variety of mechanisms including modulation of energy homeostasis and reduction of body fat mass. Indeed, restoration of islet function also plays an integral role in the remission of T2DM. After metabolic surgery, islet function in Asian T2DM patients has improved significantly, with proven short-term and long-term effects. In addition, islet function is an important criterion and reference for patient selection prior to metabolic surgery. The mechanism of islet function improvement after metabolic surgery is not clear, but postoperative anatomical changes in the gastrointestinal tract leading to a number of hormonal changes seem to be the potential cause, including glucagon-like peptide-1, gastric inhibitory polypeptide, peptide YY, ghrelin, and cholecystokinin. The authors analyzed the current retrospective and prospective studies on the effect of metabolic surgery on the islet function of Asian T2DM patients with a low BMI and its mechanism, summarized the clinical evidence that metabolic surgery improved islet function in Asian T2DM patients with a low BMI, and discussed its underlying mechanism. It is of great significance for realizing personalized and precise treatment of metabolic surgery and further improving its clinical benefits.
MeSH term(s)	Bariatric Surgery ; Body Mass Index ; Cholecystokinin/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/surgery ; Gastric Inhibitory Polypeptide/therapeutic use ; Ghrelin/therapeutic use ; Glucagon-Like Peptide 1/metabolism ; Glucagon-Like Peptide 1/therapeutic use ; Humans ; Peptide YY/metabolism ; Peptide YY/therapeutic use ; Prospective Studies ; Retrospective Studies ; Treatment Outcome
Chemical Substances	Ghrelin ; Peptide YY (106388-42-5) ; Gastric Inhibitory Polypeptide (59392-49-3) ; Glucagon-Like Peptide 1 (89750-14-1) ; Cholecystokinin (9011-97-6)
Language	Chinese
Publishing date	2022-10-17
Publishing country	China
Document type	Journal Article
ISSN	1671-0274
ISSN	1671-0274
DOI	10.3760/cma.j.cn441530-20220712-00305
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Article: [Application and value of body composition measurement in the evaluation of efficacy of bariatric and metabolic surgery].

Zhong, X X / Cui, B B / Tang, H B / Zhu, L Y / Zhu, S H

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery

2023 Volume 26, Issue 11, Page(s) 1028–1034

Abstract: The use of bariatric and metabolic surgery as a central treatment for obesity has been steadily increasing. BMI, as a widely used metric for assessing obesity, has considerable relevance in the field of metabolic research. However, its limitations, such ... ...

Abstract	The use of bariatric and metabolic surgery as a central treatment for obesity has been steadily increasing. BMI, as a widely used metric for assessing obesity, has considerable relevance in the field of metabolic research. However, its limitations, such as its inability to account for variations in fat distribution, remain a subject of considerable controversy. In recent years, there has been a surge of interest in the relationship between changes in body composition and the risk of metabolic disease. Consequently, the study of the effects of bariatric and metabolic surgery on changes in body composition has become a major focus of bariatric and metabolic surgery research. As a potential replacement for BMI, body composition measurements are expected to improve and standardize the assessment of the effectiveness of bariatric and metabolic surgery. This underscores the urgent need for the development of methods and standards for body composition measurement. This paper undertakes a comprehensive review of the existing evidence on the application of body composition measurement techniques for the efficacy evaluation of bariatric and metabolic surgery. The intent is to provide new insights and pave the way for the exploration of future research directions in this area.
MeSH term(s)	Humans ; Bariatric Surgery ; Obesity/surgery ; Body Composition ; Metabolic Diseases ; Obesity, Morbid/surgery
Language	Chinese
Publishing date	2023-04-19
Publishing country	China
Document type	Review ; English Abstract ; Journal Article
ISSN	1671-0274
ISSN	1671-0274
DOI	10.3760/cma.j.cn441530-20230816-00054
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Article: [Research advances on application of miniature free skin grafting technique].

Wang, Z J / Li, H H / Ben, C / Lu, H / Zhu, S H

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2021 Volume 37, Issue 1, Page(s) 93–96

Abstract: For the wounds caused by burns and other various reasons, the key of therapy is to close the open wounds in time by surgical operation. One of the most important methods is autologous skin grafting. However, for large area and long-term chronic trauma, ... ...

Abstract	For the wounds caused by burns and other various reasons, the key of therapy is to close the open wounds in time by surgical operation. One of the most important methods is autologous skin grafting. However, for large area and long-term chronic trauma, the lack of autologous skin makes the treatment a huge challenge. For this reason, clinical medical workers have gradually developed miniature free skin grafting through continuous research. This paper reviews the relevant skin grafting techniques, including pinch free skin grafting, stamp free skin grafting, meek grafting, microne free skin grafting, etc.
MeSH term(s)	Burns/surgery ; Humans ; Skin ; Skin Transplantation ; Wound Healing
Language	Chinese
Publishing date	2021-01-22
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.cn501120-20191223-00468
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Article: [Two cases of

Cheng, D S / Ji, S Z / Wang, G Y / Zhu, F / Xiao, S C / Zhu, S H

Zhonghua shao shang yu chuang mian xiu fu za zhi

2022 Volume 38, Issue 3, Page(s) 276–280

Abstract: This article analyzed the medical records of two patients with Vibrio vulnificus primary sepsis who were admitted to the First Affiliated Hospital of Naval Medical University and reviewed the latest literature. On November 6, 2019, a 54-year-old male ... ...

Abstract	This article analyzed the medical records of two patients with Vibrio vulnificus primary sepsis who were admitted to the First Affiliated Hospital of Naval Medical University and reviewed the latest literature. On November 6, 2019, a 54-year-old male patient was admitted to the hospital. The patient's lower limbs were red, swollen, and painful with ecchymosis and hemorrhagic bullae after he ate freshwater products. The emergency fasciotomy was performed 3 h after admission, and the multiple organ failure occurred after operation. The patient was given up treatment 24 h after admission. On August 12, 2020, a 73-year-old male patient was admitted to the hospital. He was in shock state on admission and had hemorrhagic bullae on his right lower limb after he ate seafood. At 3 h post admission, he underwent emergency surgical exploration and amputation of right thigh. Six days later, he received negative pressure wound treatment on the stump. On the 13
MeSH term(s)	Aged ; Fasciitis, Necrotizing/surgery ; Humans ; Male ; Middle Aged ; Multiple Organ Failure ; Sepsis/diagnosis ; Vibrio Infections/diagnosis ; Vibrio Infections/microbiology ; Vibrio Infections/pathology ; Vibrio vulnificus
Language	Chinese
Publishing date	2022-03-19
Publishing country	China
Document type	Case Reports ; Journal Article
ISSN	2097-1109
ISSN	2097-1109
DOI	10.3760/cma.j.cn501120-20201027-00448
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Article: [Advances in the research of artificial intelligence technology assisting the diagnosis of burn depth].

Ben, C / Li, H H / Liu, T / Wang, Z J / Cheng, D S / Zhu, S H

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2020 Volume 36, Issue 3, Page(s) 244–246

Abstract: The early accurate diagnosis of burn depth is of great significance in determining the corresponding clinical intervention methods and judging the prognosis quality of burn patients. However, the current diagnostic method of burn depth still relies ... ...

Abstract	The early accurate diagnosis of burn depth is of great significance in determining the corresponding clinical intervention methods and judging the prognosis quality of burn patients. However, the current diagnostic method of burn depth still relies mainly on the empirical subjective judgment of clinicians, with low diagnostic accuracy. Especially for deep partial-thickness burn wounds, the error of early diagnosis is pretty big. In recent years, with the rapid development of artificial intelligence technology, deep learning algorithm combined with image analysis technology can better identify and analyze the information of medical images. This article reviews the research progress of artificial intelligence technology in the diagnosis of burn depth.
MeSH term(s)	Artificial Intelligence ; Burns/diagnosis ; Burns/pathology ; Early Diagnosis ; Humans ; Prognosis ; Skin/pathology ; Technology
Language	Chinese
Publishing date	2020-04-02
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.cn501120-20190403-00162
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Article: [Application of antigen-free porcine peritoneum as carrier of autologous microskin grafting in patients with extensive burn].

Pan, B H / Sun, Y / Tang, T / Xiang, Y / Zhu, S H

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2020 Volume 36, Issue 9, Page(s) 861–864

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Adult ; Animals ; Burns/surgery ; Female ; Humans ; Male ; Peritoneum ; Skin ; Skin Transplantation ; Swine ; Transplantation, Autologous ; Wound Healing
Language	Chinese
Publishing date	2020-09-24
Publishing country	China
Document type	Journal Article
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.cn501120-20190725-00311
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Article ; Online: Correlation analysis of miR-200b, miR-200c, and miR-141 with liver metastases in colorectal cancer patients.

Zhu, S-H / He, X-C / Wang, L

European review for medical and pharmacological sciences

2017 Volume 21, Issue 10, Page(s) 2357–2363

Abstract: Objective: To investigate correlation relationship between serum miR-200b, miR-200c, miR-141 levels with liver metastases in colorectal cancer patients.: Patients and methods: A total of 85 colorectal cancer patients with liver metastases and 54 ... ...

Abstract	Objective: To investigate correlation relationship between serum miR-200b, miR-200c, miR-141 levels with liver metastases in colorectal cancer patients. Patients and methods: A total of 85 colorectal cancer patients with liver metastases and 54 colorectal cancer patients without liver metastases were divided into experimental group and control. Serum sample was collected before surgery and tested by Real-time PCR to evaluate miR-200b, miR-200c, miR-141 expressions. Results: The primary site of cancer of two groups was mostly derived from the colon cancer among the control and experimental group (there was no significant difference between the control group (61.1%) and experimental group (63.5%). Most of the invasive depth in the control group was T3 phase (50%), and most of the invasive depth in the experimental group was T4 phase (69.4%); therefore, the difference of the invasive depth between the control and experimental group is significant (p < 0.05). The majority of cases in experimental group were in stage IV, while they were in stage II in control. MiR-200b, miR-200c and miR-141 relate with tumor metastasis through epithelial mesenchymal transition (ETM) pathway, and target ZEB1 and ZEB2 genes. MiR-200b, miR-200c, and miR-141 have been confirmed to be related to tumor metastasis. miR-141 levels in serum from experimental group was higher significant compared to control group (p = 0.024). miR-200b levels in serum from experimental group was significantly increased compared to control group (p = 0.031). The miR-200c levels in serum from experimental group were significantly higher compared to control group (p = 0.015). Meanwhile, serum miR-141, miR-200b, miR-200c abnormal expressions in serum were related to tumor occurrence and development. Their levels were positively correlated with liver metastasis. Conclusions: The probability of liver metastases in colorectal cancer patients was positively correlated with serum miR-141, miR-200b, and miR-200c expressions, which could be treated as new biomarker for early diagnosis of liver metastases in colorectal cancer.
MeSH term(s)	Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Colorectal Neoplasms/blood ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Early Diagnosis ; Epithelial-Mesenchymal Transition/genetics ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Liver Neoplasms/blood ; Liver Neoplasms/genetics ; Liver Neoplasms/secondary ; MicroRNAs/blood ; MicroRNAs/genetics
Chemical Substances	Biomarkers, Tumor ; MIRN141 microRNA, human ; MIRN200 microRNA, human ; MicroRNAs
Language	English
Publishing date	2017
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
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Article: [Advances in the research of delivery system of growth factor and the gene for promoting wound healing].

Liu, T / Li, H H / Sheng, J J / Zhu, S H

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2018 Volume 34, Issue 8, Page(s) 566–569

Abstract: Growth factors play critical roles in the process of wound healing. Application of growth factor locally is a good way of promoting wound healing, while it is easy to be hydrolyzed in wounds and its efficacy has dose- and time-dependent manner. Therefore, ...

Abstract	Growth factors play critical roles in the process of wound healing. Application of growth factor locally is a good way of promoting wound healing, while it is easy to be hydrolyzed in wounds and its efficacy has dose- and time-dependent manner. Therefore, appropriate growth factor delivery system is needed to assist it to function in wounds. In addition to delivering growth factor directly to wounds, viral and non-viral vectors can be used for gene transfection of growth factor in wounds. The gene can be transformed to growth factor to promote wound healing by transcription and translation. This article reviews the advances in the research of delivery system of growth factor and the gene for promoting wound healing.
MeSH term(s)	Drug Delivery Systems/trends ; Growth Substances/therapeutic use ; Intercellular Signaling Peptides and Proteins/therapeutic use ; Transforming Growth Factor alpha/therapeutic use ; Wound Healing/drug effects
Chemical Substances	Growth Substances ; Intercellular Signaling Peptides and Proteins ; Transforming Growth Factor alpha
Language	Chinese
Publishing date	2018-08-29
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.issn.1009-2587.2018.08.018
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Article: [Advances in the research of application of artificial intelligence in burn field].

Li, H H / Bao, Z X / Liu, X B / Zhu, S H

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2018 Volume 34, Issue 4, Page(s) 246–248

Abstract: Artificial intelligence has been able to automatically learn and judge large-scale data to some extent. Based on database of a large amount of burn data and in-depth learning, artificial intelligence can assist burn surgeons to evaluate burn surface, ... ...

Abstract	Artificial intelligence has been able to automatically learn and judge large-scale data to some extent. Based on database of a large amount of burn data and in-depth learning, artificial intelligence can assist burn surgeons to evaluate burn surface, diagnose burn depth, guide fluid supply during shock stage, and predict prognosis, with high accuracy. With the development of technology, artificial intelligence can provide more accurate information for burn surgeons to make clinical diagnosis and treatment strategies.
MeSH term(s)	Artificial Intelligence ; Burns ; Humans ; Prognosis ; Shock
Language	Chinese
Publishing date	2018-04-20
Publishing country	China
Document type	Journal Article
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.issn.1009-2587.2018.04.011
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