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Article ; Online: Application of Ontology Matching Algorithm Based on Linguistic Features in English Pronunciation Quality Evaluation.

Zhu, Shan

2022 Volume 2022, Page(s) 2734672

Abstract: Traditional English classroom teaching is difficult to meet the oral learning needs of most learners. Thanks to the continuous advancement of speech processing technology, computer-assisted language learning systems are becoming more intelligent, not ... ...

Abstract	Traditional English classroom teaching is difficult to meet the oral learning needs of most learners. Thanks to the continuous advancement of speech processing technology, computer-assisted language learning systems are becoming more intelligent, not only pointing out learners' pronunciation errors but also assessing their overall pronunciation level.
MeSH term(s)	Algorithms ; Humans ; Language ; Linguistics ; Neural Networks, Computer ; Occupational Therapy
Language	English
Publishing date	2022-06-28
Publishing country	England
Document type	Journal Article ; Retracted Publication
ZDB-ID	2095334-3
ISSN	1557-0703 ; 0966-7903
ISSN (online)	1557-0703
ISSN	0966-7903
DOI	10.1155/2022/2734672
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Uncertainty quantification and attention-aware fusion guided multi-modal MR brain tumor segmentation.

Zhou, Tongxue / Zhu, Shan

Computers in biology and medicine

2023 Volume 163, Page(s) 107142

Abstract: Brain tumor is one of the most aggressive cancers in the world, accurate brain tumor segmentation plays a critical role in clinical diagnosis and treatment planning. Although deep learning models have presented remarkable success in medical segmentation, ...

Abstract	Brain tumor is one of the most aggressive cancers in the world, accurate brain tumor segmentation plays a critical role in clinical diagnosis and treatment planning. Although deep learning models have presented remarkable success in medical segmentation, they can only obtain the segmentation map without capturing the segmentation uncertainty. To achieve accurate and safe clinical results, it is necessary to produce extra uncertainty maps to assist the subsequent segmentation revision. To this end, we propose to exploit the uncertainty quantification in the deep learning model and apply it to multi-modal brain tumor segmentation. In addition, we develop an effective attention-aware multi-modal fusion method to learn the complimentary feature information from the multiple MR modalities. First, a multi-encoder-based 3D U-Net is proposed to obtain the initial segmentation results. Then, an estimated Bayesian model is presented to measure the uncertainty of the initial segmentation results. Finally, the obtained uncertainty maps are integrated into a deep learning-based segmentation network, serving as an additional constraint information to further refine the segmentation results. The proposed network is evaluated on publicly available BraTS 2018 and BraTS 2019 datasets. The experimental results demonstrate that the proposed method outperforms the previous state-of-the-art methods on Dice score, Hausdorff distance and Sensitivity metrics. Furthermore, the proposed components could be easily applied to other network architectures and other computer vision fields.
MeSH term(s)	Humans ; Bayes Theorem ; Uncertainty ; Brain Neoplasms/diagnostic imaging ; Benchmarking ; Attention ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging
Language	English
Publishing date	2023-06-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	127557-4
ISSN	1879-0534 ; 0010-4825
ISSN (online)	1879-0534
ISSN	0010-4825
DOI	10.1016/j.compbiomed.2023.107142
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Article ; Online: Multiple hyperbolic waves.

Ge, Zixun / Zhu, Shan / Xiao, Wen / Chen, Huanyang

Optics letters

2024 Volume 49, Issue 6, Page(s) 1532–1535

Abstract: This study presents a conceptual design for a hyperbolic material utilizing transformation optics. This material is designed to produce multiple hyperbolic wave fields or polaritons excited by a point source. The design dictates key parameters including ... ...

Abstract	This study presents a conceptual design for a hyperbolic material utilizing transformation optics. This material is designed to produce multiple hyperbolic wave fields or polaritons excited by a point source. The design dictates key parameters including branch number, propagation range, and overall propagation direction of deflection. Through this approach, the hyperbolic material demonstrates new effects compared to traditional hyperbolic materials. These advancements offer possibilities for the design and applications of photonic devices in other degrees of freedom.
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.513530
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Article ; Online: Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery

YANG Xiaoxuan / ZHU Shan / QIAN Cheng / CHU Xiaoying

Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 43, Iss 2, Pp 194-

2023 Volume 200

Abstract: Objective·To investigate the influence of intraoperative dexmedetomidine infusion on the recurrence-free survival (RFS) and overall survival (OS) rate of patients undergoing breast cancer surgery.Methods·A retrospective analysis was performed on patients ...

Abstract	Objective·To investigate the influence of intraoperative dexmedetomidine infusion on the recurrence-free survival (RFS) and overall survival (OS) rate of patients undergoing breast cancer surgery.Methods·A retrospective analysis was performed on patients who underwent breast cancer surgery at the Breast Disease Diagnosis and Treatment Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine from July 2013 to June 2014. Patients were divided into dexmedetomidine group and control group according to whether dexmedetomidine was injected intraoperatively at 0.7‒0.8 ìg/kg. After correcting the confounding factors between the two groups by using the propensity score matching method, the factors affecting the prognosis and survival of patients undertaking breast cancer surgery were investigated by univariate and multivariate analysis, and the Kaplan-Meier survival curve was further used to analyze the effect of intraoperative dexmedetomidine on RFS and OS after five years of breast cancer surgery.Results·There were significant differences in age, progesterone receptor (PR) positive ratio, proliferating cell nuclear antigen (Ki67) expression score, American Society of Anesthesiologists (ASA) grade, and anesthesia duration between the two groups before propensity score matching. After propensity score matching, a total of 239 pairs were successfully matched, and there was no significant difference in baseline data and perioperative data between the two groups (P>0.05). Univariate analysis showed that age (P=0.032), postoperative radiotherapy (P=0.041), Ki67 score (P=0.021), and tumor TMN stage (P=0.029) were significantly correlated with postoperative five-year OS. The results of multivariate analysis showed that postoperative radiotherapy, Ki67 score, and tumor TMN stage were significantly correlated with postoperative five-year OS (P<0.05). Intraoperative low-dose dexmedetomidine infusion was not a risk factor for postoperative five-year OS (P>0.05). Compared with the control group, the ...
Keywords	dexmedetomidine ; breast cancer ; overall survival ; recurrence-free survival ; Medicine ; R
Subject code	616 ; 610
Language	Chinese
Publishing date	2023-02-01T00:00:00Z
Publisher	Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The influencing factors of individual interest in physical education based on decision tree model: A cross-sectional study.

Lin, Jia Bin / Zhu, Shan Shan

Frontiers in psychology

2022 Volume 13, Page(s) 1015441

Abstract: To identify the key influencing factors and analyze the internal relationship among the factors of individual interest in PE, we conducted a cross-sectional survey of a large sample of Chinese young students based on the decision tree model. A total of 3, ...

Abstract	To identify the key influencing factors and analyze the internal relationship among the factors of individual interest in PE, we conducted a cross-sectional survey of a large sample of Chinese young students based on the decision tree model. A total of 3,640 young students (
Language	English
Publishing date	2022-10-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.1015441
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Article: Diagnostic and prognostic implications of non-high-density lipoprotein cholesterol and homocysteine levels for cognitive impairment in thalamic infarction.

Zhu, Shan-Yao / Ge, Wei / Zhang, Huan

World journal of psychiatry

2023 Volume 13, Issue 12, Page(s) 985–994

Abstract: Background: Patients with thalamic infarction experience abnormal blockages of multinucleated vessels, affecting the body and thereby the thalamus. Most patients with thalamic infarction have an adverse prognosis, which seriously affects their safety. ... ...

Abstract	Background: Patients with thalamic infarction experience abnormal blockages of multinucleated vessels, affecting the body and thereby the thalamus. Most patients with thalamic infarction have an adverse prognosis, which seriously affects their safety. Therefore, it is essential to analyze the independent risk factors that influence the prognosis of patients with thalamic infarction and develop corresponding preventive measures. Aim: To explore the effect of non-high-density lipoprotein cholesterol (non-HDL-C) and Homocysteine (Hcy) levels in cognitive impairment in thalamic infarction. Methods: From March 2019 to March 2022, 80 patients with thalamic infarction were divided into a group with cognitive impairment [Montreal Cognitive Assessment (MoCA) score < 26; 35 patients] and a group with normal cognitive function (MoCA score of 26-30; 45 patients) according to the MoCA score. In addition, 50 healthy people in the same period were selected as the control group. A correlation between the non-HDL-C and Hcy levels and the MoCA score and receiver operating characteristic curve was observed, and the serum non-HDL-C and Hcy levels were analyzed for the diagnosis of cognitive impairment in patients with thalamic infarction. According to the Modified Rankin Scale (MRS) score, 80 patients with thalamic infarction were divided into a good prognosis group (MRS score ≤ 2) and a poor prognosis group (MRS score >2). Results: The non-HDL-C and Hcy levels were significantly higher in the group with cognitive impairment than in the group with normal cognitive function ( Conclusion: Non-HDL-C and Hcy levels are positively correlated with cognitive impairment in patients with thalamic infarction. Non-HDL-C and Hcy levels can be used in the diagnosis of cognitive impairment in patients with thalamic infarction, and the combined detection effect is better. The main factors affecting the prognosis of patients with thalamic infarction are the non-HDL-C level, the Hcy level, the NIHSS score, large-area cerebral infarction, and atrial fibrillation. Clinically, corresponding preventive measures can be formulated based on the above factors to prevent poor prognosis and reduce mortality.
Language	English
Publishing date	2023-12-19
Publishing country	United States
Document type	Journal Article
ISSN	2220-3206
ISSN	2220-3206
DOI	10.5498/wjp.v13.i12.985
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Article ; Online: Endoscopic ultrasound-guided partial splenic embolization for hypersplenism: a novel alternative.

Liu, Ping / Zhu, Shan-Shan / Cao, Xin-Guang / Kongkam, Pradermchai / Ullah, Saif / Guo, Chang-Qing

Endoscopy

2024 Volume 56, Issue S 01, Page(s) E144–E145

MeSH term(s)	Humans ; Hypersplenism/diagnostic imaging ; Hypersplenism/etiology ; Hypersplenism/therapy ; Endosonography ; Embolization, Therapeutic ; Ultrasonography, Interventional ; Splenic Artery/diagnostic imaging
Language	English
Publishing date	2024-02-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/a-2244-4009
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Zs.A 669: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 162: Show issues

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Article ; Online: Endoscopic resection of a huge tumor located at an anatomically challenging position using an innovative extra snare traction method.

Cao, Xin-Guang / Ullah, Saif / Zhu, Shan-Shan / Dai, Nan / Guo, Chang-Qing

Endoscopy

2024 Volume 56, Issue S 01, Page(s) E203–E204

MeSH term(s)	Humans ; Traction ; Endoscopy ; Neoplasms ; Endoscopic Mucosal Resection ; Treatment Outcome
Language	English
Publishing date	2024-03-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/a-2261-7794
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Zs.A 669: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: A Serum Pharmacochemistry and Network Pharmacology-based Approach to Study the Anti-depressant Effect of Chaihu-Shugan San.

Deng, Man-Fei / Yan, Yi-Zhi / Zhu, Shan-Shan / Zhou, Ke / Tan, Si-Jie / Zeng, Peng

Combinatorial chemistry & high throughput screening

2024

Abstract: Aims: The aim of this study is to explore the anti-depressant mechanism of Chaihu- Shugan San based on serum medicinal chemistry and network pharmacology methods.: Background: Depression lacks effective treatments, with current anti-depressants ... ...

Abstract	Aims: The aim of this study is to explore the anti-depressant mechanism of Chaihu- Shugan San based on serum medicinal chemistry and network pharmacology methods. Background: Depression lacks effective treatments, with current anti-depressants ineffective in 40% of patients. Chaihu-Shugan San (CHSGS) is a well-known traditional Chinese medicine compound to treat depression. However, the chemical components and the underlying mechanisms targeting the liver and brain in the anti-depressant effects of CHSGS need to be elucidated. Methods: The chemical components of CHSGS in most current network pharmacology studies are screened from TCMSP and TCMID databases. In this study, we investigated the mechanism and material basis of soothing the liver and relieving depression in the treatment of depression by CHSGS based on serum pharmacochemistry. The anti-depressant mechanism of CHSGS was further verified by proteomics and high-throughput data. Results: Through serum medicinal chemistry, we obtained 9 bioactive substances of CHSGS. These ingredients have good human oral bioavailability and are non-toxic. Based on liver ChIPseq data, CHSGS acts on 8 targets specifically localized in the liver, such as FGA, FGB, and FGG. The main contributors to CHSGS soothing the liver qi targets are hesperetin, nobiletin, ferulic acid, naringin and albiflorin. In addition, network pharmacology analysis identified 9 blood components of CHSGS that corresponded to 63 anti-depressant targets in the brain. Among them, nobiletin has the largest number of anti-depressant targets, followed by glycyrrhizic acid, ferulic acid, albiflorin and hesperetin. We also validated the anti-depressant mechanism of CHSGS based on hippocampal proteomics. CHSGS exerts anti-depressant effects on synaptic structure and neuronal function by targeting multiple synapse related proteins. Conclusion: This study not only provides a theoretical basis for further expanding the clinical application of CHSGS, but also provides a series of potential lead compounds for the development of depression drugs.
Language	English
Publishing date	2024-03-28
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2064785-2
ISSN	1875-5402 ; 1386-2073
ISSN (online)	1875-5402
ISSN	1386-2073
DOI	10.2174/0113862073285198240322072301
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Zs.A 5577: Show issues

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Article ; Online: A New Option to Preserve Esthetics in Perioral Defect Reconstruction With Normal Anatomical Structures: Bipedicled Preexpanded Forehead Flap With Random Skin Flap Extension.

Yang, Ruomeng / Jin, Shengyang / Zang, Mengqing / Zhu, Shan / Li, Shanshan / Han, Tinglu / Liu, Yuanbo

The Journal of craniofacial surgery

2024

Abstract: Plastic surgeons charged with reconstructing extensive perioral defects face dual challenges of functional restoration and esthetic considerations. While forehead flaps are commonly used to reconstruct perioral defects, in cases involving partial upper ... ...

Abstract	Plastic surgeons charged with reconstructing extensive perioral defects face dual challenges of functional restoration and esthetic considerations. While forehead flaps are commonly used to reconstruct perioral defects, in cases involving partial upper lip defects where normal anatomical structures are preserved, traditional forehead flaps may compromise esthetics. This study aimed to address this issue by employing bipedicled preexpanded forehead flaps based on the frontal branches of the superficial temporal artery (hereafter, "STA-bfb-based preexpanded forehead flap") with random flap extensions to repair perioral defects. Between April 2004 and July 2020, 7 patients (5 males and 2 females; 6 had post-burn facial scars involving the entire lower lip and part of the upper lip, and 1 presented with noma sequelae) underwent perioral defect reconstruction using this approach. Tissue expanders were placed in the forehead donor area, and an STA-bfb-based preexpanded forehead flap with random flap extensions was used to repair the perioral defect. The flap pedicle was divided into 3 weeks. All flaps remained viable with no perfusion-related complications. At follow-up 12 to 96 months later, the color and texture of the flaps demonstrated excellent compatibility with the surrounding skin, suggesting that the use of an STA-bfb-based preexpanded forehead flap with random skin flap extensions is a reliable method for repairing perioral defects. The authors' results have implications for plastic surgeons seeking a solution for challenging perioral defect reconstructions, balancing the need for esthetic outcomes with functional restoration.
Language	English
Publishing date	2024-05-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000010217
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Zs.MO 175: Show issues

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