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  1. AU="Zhu, Wen-Yi"
  2. AU="Bartolomé-Comas, Rosa"
  3. AU="Mathew, Josey"
  4. AU="Ali A. Shati"
  5. AU="Tavares, Guilherme M"
  6. AU="Deoni, Sean"
  7. AU="Byrne, Michael E"
  8. AU=Edwards Adrianne N.
  9. AU=Mehr Reyhaneh Niayesh
  10. AU="Par-Young, Jennefer"
  11. AU="Yon, Yongjie"
  12. AU="Laisi, Arttu"
  13. AU="Huang, Haibing"
  14. AU="Volk, Michelle"
  15. AU="Zijlstra, J. G."
  16. AU="Aditya Narayan"
  17. AU="Soliño, S. López"
  18. AU="Bervoets, Lieven"
  19. AU=Perween Reshma AU=Perween Reshma
  20. AU="Wang, Zhenduo"

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  1. Artikel: LncRNA ANRIL promotes multiple myeloma progression and bortezomib resistance by EZH2-mediated epigenetically silencing of PTEN.

    Yang, Li-Hui / Du, Peng / Liu, Wei / An, Li-Kun / Li, Jian / Zhu, Wen-Yi / Yuan, Shuo / Wang, Lei / Zang, Lei

    Neoplasma

    2021  Band 68, Heft 4, Seite(n) 788–797

    Abstract: Multiple myeloma (MM) is a plasma cell malignancy of bone marrow. In the present study, we aimed to study the function and potential mechanism of the antisense non-coding RNA in the INK4 Locus (ANRIL) in MM. The expression levels of ANRIL in MM patients ... ...

    Abstract Multiple myeloma (MM) is a plasma cell malignancy of bone marrow. In the present study, we aimed to study the function and potential mechanism of the antisense non-coding RNA in the INK4 Locus (ANRIL) in MM. The expression levels of ANRIL in MM patients and healthy donors were evaluated by quantitative real-time polymerase chain reaction (qRT-PCR). The effects and mechanisms of ANRIL in MM were evaluated by cell viability assay, BrdU incorporation assay, tumor xenograft model, flow cytometry, western blot, RNA immunoprecipitation (RIP), transcriptome RNA sequencing, and chromatin immunoprecipitation (ChIP). We found that ANRIL was upregulated in MM patients and cell lines, and associated with advanced international staging system (ISS) stage and poor overall survival. Enforced ANRIL expression promoted proliferation and tumor xenograft growth of MM cells, while knockdown of ANRIL exhibited opposite effects. Moreover, ANRIL overexpression increased the half-maximal inhibitory concentration (IC50) of bortezomib and reduced bortezomib-induced apoptosis in MM cells. ANRIL was found to accumulate in the nuclei of MM cells, and interact with EZH2 by RIP assay. Transcriptome RNA sequencing identified PTEN as a target of ANRIL in MM cells. In the ChIP assay, knockdown of ANRIL reduced EZH2 occupancy and H3K27me3 binding to the promoter region of PTEN. Furthermore, EZH2 knockout or PTEN restoration abrogated the effects caused by ANRIL overexpression in MM cells. Our results indicated that ANRIL exerted oncogenic functions and conferred chemoresistance of MM cells by EZH2-mediated epigenetically silencing of PTEN.
    Mesh-Begriff(e) Apoptosis ; Bortezomib/pharmacology ; Cell Proliferation ; Enhancer of Zeste Homolog 2 Protein/genetics ; Humans ; Multiple Myeloma/drug therapy ; Multiple Myeloma/genetics ; PTEN Phosphohydrolase/genetics ; RNA, Long Noncoding/genetics
    Chemische Substanzen RNA, Long Noncoding ; Bortezomib (69G8BD63PP) ; EZH2 protein, human (EC 2.1.1.43) ; Enhancer of Zeste Homolog 2 Protein (EC 2.1.1.43) ; PTEN Phosphohydrolase (EC 3.1.3.67) ; PTEN protein, human (EC 3.1.3.67)
    Sprache Englisch
    Erscheinungsdatum 2021-05-26
    Erscheinungsland Slovakia
    Dokumenttyp Journal Article
    ZDB-ID 415445-9
    ISSN 0028-2685
    ISSN 0028-2685
    DOI 10.4149/neo_2021_210205N184
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: A biomechanical study on proximal junctional kyphosis following long-segment posterior spinal fusion.

    Zhu, Wen-Yi / Zang, Lei / Li, Jian / Guan, Li / Hai, Yong

    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

    2019  Band 52, Heft 5, Seite(n) e7748

    Abstract: Posterior long-segment spinal fusion may lead to proximal junctional kyphosis (PJK). The present study sought to identify the appropriate fusion levels required in order to prevent PJK using finite element analysis. A finite element model was constructed ...

    Abstract Posterior long-segment spinal fusion may lead to proximal junctional kyphosis (PJK). The present study sought to identify the appropriate fusion levels required in order to prevent PJK using finite element analysis. A finite element model was constructed based on the whole-spine computed tomography findings of a healthy adult. Nine commonly used posterior spinal fusion methods were selected. Stress on the annulus fibrosis fibers, the posterior ligamentous complex, and the vertebrae after various spinal fusions in the upright position were compared. This study was divided into two groups: non-fusion and fusion. In the former, the stress between the T10 and the upper thoracic vertebrae was higher. Comparing thoracic and lumbar segments in the fusion group, the peak stress values of the upper instrumented vertebrae (UIV) were mainly observed in T2 and L2 whilst those of the UIV+1 were observed in T10 and L2. After normalization, the peak stress values of the UIV and UIV+1 were located in T2 and L2. Similarly, the peak stress values of the annulus fibrosus at the upper adjacent level were on T10 and L2 after normalization. However, the peak stress values of the interspinal/supraspinal complex forces were concentrated on T11, T12, and L1 after normalization whilst the peak stress value of the pedicle screw was on T2. Controversy remains over the fusion of T10, and this study simulated testing conditions with gravitational loading only. However, further assessment is needed prior to reaching definitive conclusions.
    Mesh-Begriff(e) Biomechanical Phenomena ; Humans ; Imaging, Three-Dimensional ; Kyphosis/surgery ; Lumbar Vertebrae/surgery ; Male ; Middle Aged ; Orthopedics/methods ; Scoliosis/surgery ; Spinal Fusion/instrumentation ; Spinal Fusion/methods
    Sprache Englisch
    Erscheinungsdatum 2019-04-25
    Erscheinungsland Brazil
    Dokumenttyp Journal Article
    ZDB-ID 786234-9
    ISSN 1414-431X ; 0100-879X
    ISSN (online) 1414-431X
    ISSN 0100-879X
    DOI 10.1590/1414-431X20197748
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Lumbar decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis: A systematic review and meta-analysis.

    Yang, Li-Hui / Liu, Wei / Li, Jian / Zhu, Wen-Yi / An, Li-Kun / Yuan, Shuo / Ke, Han / Zang, Lei

    Medicine

    2020  Band 99, Heft 27, Seite(n) e20323

    Abstract: Background: The goal of this study was to review relevant randomized controlled trials in order to determine the efficacy of decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis.: Method: Using appropriate keywords, we ...

    Abstract Background: The goal of this study was to review relevant randomized controlled trials in order to determine the efficacy of decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis.
    Method: Using appropriate keywords, we identified relevant studies in PubMed, the Cochrane library, and Embase. Key pertinent sources in the literature were also reviewed, and all articles published through July 2019 were considered for inclusion. For each study, we assessed odds ratios, mean difference, and 95% confidence interval to assess and synthesize outcomes.
    Result: Twenty-one randomized controlled trials were eligible for this meta-analysis with a total of 3636 patients. Compared with decompression, decompression and fusion significantly increased length of hospital stay, operative time and estimated blood loss. Compared with fusion, decompression significantly decreased operative time, estimated blood loss and overall visual analogue scale (VAS) scores. Compared with endoscopic decompression, microscopic decompression significantly increased length of hospital stay, and operative time. Compared with traditional surgery, endoscopic discectomy significantly decreased length of hospital stay, operative time, estimated blood loss, and overall VAS scores and increased Japanese Orthopeadic Association score. Compared with TLIF, MIS-TLIF significantly decreased length of hospital stay, and increased operative time and SF-36 physical component summary score. Compared with multi-level decompression and single level fusion, multi-level decompression and multi-level fusion significantly increased operative time, estimated blood loss and SF-36 mental component summary score and decreased Oswestry disability index score. Compared with decompression, decompression with interlaminar stabilization significantly decreased operative time and the score of Zurich claudication questionnaire symptom severity, and increased VAS score.
    Conclusion: Considering the limited number of included studies, we still need larger-sample, high-quality, long-term studies to explore the optimal therapy for lumbar spinal stenosis.
    Mesh-Begriff(e) Blood Loss, Surgical ; Decompression, Surgical/statistics & numerical data ; Humans ; Length of Stay ; Lumbar Vertebrae/surgery ; Operative Time ; Spinal Fusion/methods ; Spinal Fusion/statistics & numerical data ; Spinal Stenosis/surgery
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-07-06
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000020323
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Predictability of Urinary CD80 in the Relapse of Primary Nephrotic Syndrome

    Juan Liao / Xiao-Chuan Wu / Qia Cheng / Can-Lin Li / Zhu-Wen Yi / Yan Cao / Lan-Jun Shuai

    BioMed Research International, Vol

    2017  Band 2017

    Abstract: Purpose. The current study is aimed at investigating whether urinary CD80 is reliable to predict the recurrence of pediatric PNS. Materials and Methods. A total of 128 children, 105 males and 23 females, were enrolled in this study. Urinary samples were ... ...

    Abstract Purpose. The current study is aimed at investigating whether urinary CD80 is reliable to predict the recurrence of pediatric PNS. Materials and Methods. A total of 128 children, 105 males and 23 females, were enrolled in this study. Urinary samples were collected from SSNS and SRNS patients and 25 healthy children as controls. Urinary CD80 was measured by ELISA and adjusted for urinary creatinine excretion. Results. Urinary CD80 in relapse stage of SSNS was significantly higher, and the urinary CD80 of paired relapse and remission stages of each SSNS patient were also significantly different. No significant difference was found between the urinary CD80 in SRNS relapse group, SRNS remission group, and the control group. Similarly, there was no significant difference between frequent SSNS and not frequent SSNS in remission group, as well as the relapse group. There is no correlation between urinary CD80 and 24-hour urinary protein. Conclusion. The increase of urinary CD80 was closely associated with the relapse of SSNS but was not related to the frequency of relapse. The urinary CD80 changes of concentration were reliable to predict the recurrence of SSNS. However, it cannot be used to predicate the frequent recurrence of PNS.
    Schlagwörter Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2017-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel: Lumbar decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis: A systematic review and meta-analysis

    Yang, Li-Hui / Liu, Wei / Li, Jian / Zhu, Wen-Yi / An, Li-Kun / Yuan, Shuo / Ke, Han / Zang, Lei

    Medicine (Baltimore)

    Abstract: BACKGROUND: The goal of this study was to review relevant randomized controlled trials in order to determine the efficacy of decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis. METHOD: Using appropriate keywords, we ... ...

    Abstract BACKGROUND: The goal of this study was to review relevant randomized controlled trials in order to determine the efficacy of decompression and lumbar interbody fusion in the treatment of lumbar spinal stenosis. METHOD: Using appropriate keywords, we identified relevant studies in PubMed, the Cochrane library, and Embase. Key pertinent sources in the literature were also reviewed, and all articles published through July 2019 were considered for inclusion. For each study, we assessed odds ratios, mean difference, and 95% confidence interval to assess and synthesize outcomes. RESULT: Twenty-one randomized controlled trials were eligible for this meta-analysis with a total of 3636 patients. Compared with decompression, decompression and fusion significantly increased length of hospital stay, operative time and estimated blood loss. Compared with fusion, decompression significantly decreased operative time, estimated blood loss and overall visual analogue scale (VAS) scores. Compared with endoscopic decompression, microscopic decompression significantly increased length of hospital stay, and operative time. Compared with traditional surgery, endoscopic discectomy significantly decreased length of hospital stay, operative time, estimated blood loss, and overall VAS scores and increased Japanese Orthopeadic Association score. Compared with TLIF, MIS-TLIF significantly decreased length of hospital stay, and increased operative time and SF-36 physical component summary score. Compared with multi-level decompression and single level fusion, multi-level decompression and multi-level fusion significantly increased operative time, estimated blood loss and SF-36 mental component summary score and decreased Oswestry disability index score. Compared with decompression, decompression with interlaminar stabilization significantly decreased operative time and the score of Zurich claudication questionnaire symptom severity, and increased VAS score. CONCLUSION: Considering the limited number of included studies, we still need larger-sample, high-quality, long-term studies to explore the optimal therapy for lumbar spinal stenosis.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32629626
    Datenquelle COVID19

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  6. Artikel: Investigating Conservative Therapy of Cervical Radiculopathy by a Delphi Technique.

    Li, Jian / Zhu, Wen-Yi / Zang, Lei / Hai, Yong / Du, Peng / Fan, Ning / Zhou, Yu / An, Li-Kun

    Chinese medical journal

    2015  Band 128, Heft 21, Seite(n) 2976

    Mesh-Begriff(e) Delphi Technique ; Humans ; Radiculopathy/drug therapy ; Radiculopathy/surgery ; Radiculopathy/therapy
    Sprache Englisch
    Erscheinungsdatum 2015-11-05
    Erscheinungsland China
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 127089-8
    ISSN 0366-6999 ; 1002-0187
    ISSN 0366-6999 ; 1002-0187
    DOI 10.4103/0366-6999.168082
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: [Distribution and role of motilin receptor in the amygdala of rats].

    Liu, Mei / Dong, Lei / Zhu, Wen-yi

    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

    2005  Band 25, Heft 9, Seite(n) 1100–1104

    Abstract: Objective: To explore the distribution and role of motilin receptor in the amygdala of rats.: Methods: The distribution of motilin receptor in the amygdala was detected by immunohistochemistry in adult SD rats of either sex. The duodenal ... ...

    Abstract Objective: To explore the distribution and role of motilin receptor in the amygdala of rats.
    Methods: The distribution of motilin receptor in the amygdala was detected by immunohistochemistry in adult SD rats of either sex. The duodenal interdigestive migrating myoelectric complex (MMC) was recorded and analyzed for investigating the role of motilin receptor in the amygdala.
    Results: Motilin receptors were detected in the amygdala of rats. The medial amygdaloid nucleus contained the greatest amount of motilin receptors, which was also abound in the basolateral nucleus of the amygdala but less abundant in the basomedial nucleus of the amygdala, central amygdaloid nucleus and lateral amygdaloid nucleus. The binding of motilin receptors and motilin in the amygdala caused shortening of duodenal MMC cycle duration and increased amplitude and frequency of phase III. The effects were completely abolished by subdiaphragmal vagotomy but not by intravenous injection of atropine, phentolamine or propranolol. Anti-motilin serum partially abolished these effects, and destruction of the basolateral nucleus of the amygdala had no effects on duodenal MMC.
    Conclusions: Motilin receptors are present in all the subnuclei of the amygdala. The effects of microinjection of motilin in the amygdala on duodenal MMC might rely on either the effects of noncholinergic and nonadrenergic neurons on the duodenal smooth muscle, or increase in local motilin via amygdala-hypothalamus-brain stem-vagus pathway, indicating the important role of motilin receptor in the amygdala in duodenal MMC regulation.
    Mesh-Begriff(e) Amygdala/metabolism ; Amygdala/physiology ; Animals ; Duodenum/physiology ; Female ; Male ; Motilin/administration & dosage ; Myoelectric Complex, Migrating ; Rats ; Rats, Sprague-Dawley ; Receptors, Gastrointestinal Hormone/metabolism ; Receptors, Gastrointestinal Hormone/physiology ; Receptors, Neuropeptide/metabolism ; Receptors, Neuropeptide/physiology
    Chemische Substanzen Receptors, Gastrointestinal Hormone ; Receptors, Neuropeptide ; motilin receptor ; Motilin (52906-92-0)
    Sprache Chinesisch
    Erscheinungsdatum 2005-09
    Erscheinungsland China
    Dokumenttyp English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1175025-x
    ISSN 1000-2588
    ISSN 1000-2588
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: [Oxidative damages in rats induced by the diet from Yanting region with high prevalence of esophageal cancers].

    Zhu, Wen-yi / Jiang, Yan / Huang, Cheng-yu / Li, Ming

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2008  Band 39, Heft 5, Seite(n) 769–771

    Abstract: Objective: To test the effect of the diet from Yanting region, a region with high prevalence of esophagus cancers, on oxidative damages in rats.: Methods: Thirty male SD rats were randomly divided into three experimental groups and fed with standard ... ...

    Abstract Objective: To test the effect of the diet from Yanting region, a region with high prevalence of esophagus cancers, on oxidative damages in rats.
    Methods: Thirty male SD rats were randomly divided into three experimental groups and fed with standard diets, Yanting diets, and Chengdu diets (a region with low prevalence of esophageal cancers), respectively. One month later, the rats were killed. The livers and esophagus of those rats were taken immediately and were weighted, homogenated, and centrifuged at a low temperature to dissociate the supernatants. The contents of NO and MDA and the activities of NOS, SOD, CAT, and GSH-Px in the supernatants were measured.
    Results: The rats fed with Chengdu diets showed no differences with those fed with standard diets. But the rats fed with Yanting diets had significantly higher NO, MDA and NOS, and lower activities of SOD, CAT, and GSH-Px in the livers than those fed with Chengdu diets. The rats fed with Yanting diets also had higher MHA and lower CAT in the esophagus than those fed with Chengdu diets.
    Conclusion: Yanting diets stimulate the oxidative damages of the livers and esophagus in rats.
    Mesh-Begriff(e) Animals ; China/epidemiology ; Diet ; Esophageal Neoplasms/epidemiology ; Esophageal Neoplasms/etiology ; Female ; Humans ; Male ; Nitric Oxide/metabolism ; Oxidative Stress ; Prevalence ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Superoxide Dismutase/metabolism
    Chemische Substanzen Nitric Oxide (31C4KY9ESH) ; Superoxide Dismutase (EC 1.15.1.1)
    Sprache Chinesisch
    Erscheinungsdatum 2008-09
    Erscheinungsland China
    Dokumenttyp English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Does injection of metanephric mesenchymal cells improve renal function in rats?

    Yu-qing Jiao / Zhu-wen Yi / Xiao-jie He / Xi-hong Liu / Qing-nan He / Dan-lin Huang

    Saudi Journal of Kidney Diseases and Transplantation, Vol 22, Iss 3, Pp 501-

    2011  Band 510

    Abstract: Chronic kidney disease (CKD) is a massive global health-care problem. Cell therapy offers a potential treatment for CKD. The aim of this study was to investigate whether the administration of a population of stem cells could be used to treat adriamycin ( ... ...

    Abstract Chronic kidney disease (CKD) is a massive global health-care problem. Cell therapy offers a potential treatment for CKD. The aim of this study was to investigate whether the administration of a population of stem cells could be used to treat adriamycin (ADR)-induced glomerulopathy in rats, a form of CKD. We intravenously transplanted metanephric mesenchymal cells (MMCs) into rats treated with ADR. We also induced MMC differentiation in vitro using a medium derived from serum and homogenates of ADR-induced glomerulopathy rats. We detected the induction of an early epithelial phenotype (cytokeratin-18 expression) and a proximal tubule phenotype (vitamin D receptor expression) in vitro, and MMC-derived epithelial cells corresponding to the proximal tubule and glomeruli in vivo. Transplantation of MMCs after induction of glomerulopathy significantly increased the creatinine clearance rate (Ccr), a marker for glomerular filtration rate, but had no significant effect on other parameters (24-hour urinary protein excretion, serum albumin, total cholesterol). In addition, there was no significant difference in blood urea nitrogen or serum creatinine levels in rats with and without ADR administration. Our results indicate that MMCs might survive, engraft and differentiate into renal epithelia in vivo when transplanted into ADR-treated rats. However, further studies are needed to determine whether MMC transplantation improves renal function and causes renal repair in this model.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2011-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
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  10. Artikel: [Effects of Yanting diet and vitamins on growth and proliferation of human esophageal cancer cell line].

    Jiang, Yan / Zhu, Wen-yi / Huang, Cheng-yua / Tao, De-ming

    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

    2007  Band 38, Heft 4, Seite(n) 624–628

    Abstract: Objective: The effects of sera of rats fed the Yanting diet (YT diet) on growth and proliferation of the human esophageal cancer cell line Eca-109 were observed by the means of sero-physiology.: Methods: The male SD rats, randomly divided into six ... ...

    Abstract Objective: The effects of sera of rats fed the Yanting diet (YT diet) on growth and proliferation of the human esophageal cancer cell line Eca-109 were observed by the means of sero-physiology.
    Methods: The male SD rats, randomly divided into six groups with ten each, were fed a conventional diet and five experimental diets, i.e. YT diet, the YT diet with two vitamin mixtures (Mix. 1, vit. A, E and folic acid; Mix. 2 was Mix. 1 plus riboflavin and vit. C) at two doses. After rats fed different diets for 30 days, rats' sera were collected and added into medium for cell culture. The effects serum of rats fed different diets on two human cell lines (Eca-109 esophageal cancer cell and HL7702 normal liver epithelium cell) were investigated by means of cell growth curve, 3H-thymidine incorporation and flow cytometric assay.
    Results: By comparison with the control, the sera of rats fed the YT diet significantly promoted Eca-109 cell proliferation but showed inhibitory effects on HL7702 cell. These changes, however, were reversed by supplementation with two vitamin mixtures at high dose, which had more significant effects on either inhibiting Eca-109 cell or promoting HL7702 cell proliferation than the corresponding lower dose. In addition, the high dose of two vitamin mixtures caused G1 arrest of Eca-109 cell, while speeding the HL7702 cell entering into S and G2 of cell cycle. No obvious difference was seen between both serum of rat fed with the conventional diet and calf serum as control to effect on the two cell line growths and proliferations.
    Conclusion: It is indicated that the sera of rats fed with the YT diet could promote the proliferation of human esophageal cancer cell line Eca-109; the YT diet supplemented with vitamin mixtures may have inhibitory effects on Eca-109 cell. The cell cycle arrest of G1 may be one of the mechanisms that the YT diet supplemented with vitamin mixtures inhibited the proliferation of Eca-109 cell.
    Mesh-Begriff(e) Animals ; Body Weight/drug effects ; Cattle ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Diet ; Esophageal Neoplasms/diet therapy ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/physiopathology ; Humans ; Male ; Rats ; Rats, Sprague-Dawley ; Risk ; Vitamins/pharmacology
    Chemische Substanzen Vitamins
    Sprache Chinesisch
    Erscheinungsdatum 2007-07
    Erscheinungsland China
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 2106840-9
    ISSN 1672-173X
    ISSN 1672-173X
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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