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  1. Article ; Online: Characterization of Epoxy-Based Rapid Mold with Profiled Conformal Cooling Channel.

    Kuo, Chil-Chyuan / Zhu, Yi-Jun

    Polymers

    2022  Volume 14, Issue 15

    Abstract: Based on the experience of the foundry industry, reducing the demolding time is the key for mass production of wax patterns with sophisticated geometries. Integration of numerical simulation and rapid tooling technology for decreasing the time to market ... ...

    Abstract Based on the experience of the foundry industry, reducing the demolding time is the key for mass production of wax patterns with sophisticated geometries. Integration of numerical simulation and rapid tooling technology for decreasing the time to market is essential in advanced manufacturing technology. However, characterization of epoxy-based rapid molds with a profiled conformal cooling channel (PCCC) using computer-aided engineering simulation of the epoxy-based rapid mold with PCCC was not found in the literature. In this study, epoxy-based rapid molds with PCCC were characterized numerically and experimentally. The cooling performance of wax injection molds with two different kinds of cross-sections of the cooling channel was investigated. Four pairs of injection molds with PCCC were implemented using four different kinds of material formulations. It was found that the cooling performance of the PCCC was better than a circular conformal cooling channel (CCCC) since the PCCC maintained a more uniform and steady cooling performance of injection-molded product than CCCC. Epoxy resin added with 41 vol.% Cu powder seems to be a cost-effective empirical material formulation in terms of cooling time and material costs. This empirical material formulation provided an injection mold with low material cost and good cooling performance simultaneously compared to an injection mold fabricated with commercial material. The cooling performance could reach 88% of that of the injection mold fabricated with commercial material. The material cost of making the injection mold was only about 60% of that of the injection mold fabricated with commercial material. The coolant flow rate had no significant effect on the cooling time, whereas the cooling time of the wax pattern was affected by coolant temperature significantly.
    Language English
    Publishing date 2022-07-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14153017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Combinatorial expression of γ-protocadherins regulates synaptic connectivity in the mouse neocortex.

    Zhu, Yi-Jun / Deng, Cai-Yun / Fan, Liu / Wang, Ya-Qian / Zhou, Hui / Xu, Hua-Tai

    eLife

    2024  Volume 12

    Abstract: In the process of synaptic formation, neurons must not only adhere to specific principles when selecting synaptic partners but also possess mechanisms to avoid undesirable connections. Yet, the strategies employed to prevent unwarranted associations have ...

    Abstract In the process of synaptic formation, neurons must not only adhere to specific principles when selecting synaptic partners but also possess mechanisms to avoid undesirable connections. Yet, the strategies employed to prevent unwarranted associations have remained largely unknown. In our study, we have identified the pivotal role of combinatorial clustered protocadherin gamma (γ-PCDH) expression in orchestrating synaptic connectivity in the mouse neocortex. Through 5' end single-cell sequencing, we unveiled the intricate combinatorial expression patterns of γ-PCDH variable isoforms within neocortical neurons. Furthermore, our whole-cell patch-clamp recordings demonstrated that as the similarity in this combinatorial pattern among neurons increased, their synaptic connectivity decreased. Our findings elucidate a sophisticated molecular mechanism governing the construction of neural networks in the mouse neocortex.
    MeSH term(s) Animals ; Mice ; Cadherin Related Proteins ; Cadherins/genetics ; Neocortex ; Neural Networks, Computer
    Chemical Substances Gamma-protocadherins ; Cadherin Related Proteins ; Cadherins
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.89532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Bloodstream infection caused by Solobacteriummoorei: A case report and literature review.

    Yu, Qian / Xu, Qianqian / Zhu, Yi Jun

    Indian journal of medical microbiology

    2022  Volume 42, Page(s) 85–88

    Abstract: Solobacterium moorei is an asporogenous, strictly anaerobic, short-to-long bacillus belonging to the family Erysipelotrichidae and phylum Firmicutes. This bacterium rarely causes bloodstream infections. Here, we report a case of the postoperative ... ...

    Abstract Solobacterium moorei is an asporogenous, strictly anaerobic, short-to-long bacillus belonging to the family Erysipelotrichidae and phylum Firmicutes. This bacterium rarely causes bloodstream infections. Here, we report a case of the postoperative recurrence and metastasis of gastric antral adenocarcinoma combined with S. moorei bloodstream infection.
    MeSH term(s) Humans ; Sepsis ; Bacteremia/diagnosis ; Bacteremia/microbiology ; RNA, Ribosomal, 16S ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2022-11-15
    Publishing country United States
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2022.10.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effects of Different Mold Materials and Coolant Media on the Cooling Performance of Epoxy-Based Injection Molds.

    Kuo, Chil-Chyuan / Xu, Jing-Yan / Zhu, Yi-Jun / Lee, Chong-Hao

    Polymers

    2022  Volume 14, Issue 2

    Abstract: Metal additive manufacturing techniques are frequently applied to the manufacturing of injection molds with a conformal cooling channel (CCC) in order to shorten the cooling time in the injection molding process. Reducing the cooling time in the cooling ... ...

    Abstract Metal additive manufacturing techniques are frequently applied to the manufacturing of injection molds with a conformal cooling channel (CCC) in order to shorten the cooling time in the injection molding process. Reducing the cooling time in the cooling stage is essential to reducing the energy consumption in mass production. However, the distinct disadvantages include higher manufacturing costs and longer processing time in the fabrication of injection mold with CCC. Rapid tooling technology (RTT) is a widely utilized technology to shorten mold development time in the mold industry. In principle, the cooling time of injection molded products is affected by both injection mold material and coolant medium. However, little work has been carried out to investigate the effects of different mold materials and coolant media on the cooling performance of epoxy-based injection molds quantitatively. In this study, the effects of four different coolant media on the cooling performance of ten sets of injection molds fabricated with different mixtures were investigated experimentally. It was found that cooling water with ultrafine bubble is the best cooling medium based on the cooling efficiency of the injection molded parts (since the cooling efficiency is increased further by about 12.4% compared to the conventional cooling water). Mold material has a greater influence on the cooling efficiency than the cooling medium, since cooling time range of different mold materials is 99 s while the cooling time range for different cooling media is 92 s. Based on the total production cost of injection mold and cooling efficiency, the epoxy resin filled with 41 vol.% aluminum powder is the optimal formula for making an injection mold since saving in the total production cost about 24% is obtained compared to injection mold made with commercially available materials.
    Language English
    Publishing date 2022-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14020280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: RIS-aided dynamically adaptive wide field-of-view receiver for visible light communication in industrial internet of things.

    Ye, Zi-Wei / Zhang, Yan-Yu / Wang, Chao / Fan, Peng-Hui / Zhu, Yi-Jun

    Optics express

    2023  Volume 31, Issue 21, Page(s) 34748–34763

    Abstract: In the current visible light communication (VLC) system, a condenser lens is generally used in the front of receiver to achieve a higher data rate, making an extremely narrow field-of-view for the receiver. With the spread of Industrial Internet of ... ...

    Abstract In the current visible light communication (VLC) system, a condenser lens is generally used in the front of receiver to achieve a higher data rate, making an extremely narrow field-of-view for the receiver. With the spread of Industrial Internet of Things (IIoT), the communication between mobile terminals is urgently required. A wide-range detecting method for VLC system in IIoT scenario is asked. In this paper, a novel self-adaptive wide-FoV receiver involving reconfigurable intelligent surfaces (RIS) is proposed. The effective detecting range of the receiver can be expanded by dynamically adjusting the incident light directions with the assistance of RIS. Based on the maximum arrived flux criterion, the mathematical model is established and the optimized RIS parameter tuning algorithm is presented. The feasibility and validity of the method are verified by simulation. The results show that the tolerable transceiver offset can be increased to 2∼4 times as the conventional receiver.
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.500805
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Rapid Development of an Injection Mold with High Cooling Performance Using Molding Simulation and Rapid Tooling Technology.

    Kuo, Chil-Chyuan / Nguyen, Trong-Duc / Zhu, Yi-Jun / Lin, Shi-Xun

    Micromachines

    2021  Volume 12, Issue 3

    Abstract: Rapid tooling technology (RTT) provides an alternative approach to quickly provide wax injection molds for the required products since it can reduce the time to market compared with conventional machining approaches. Removing conformal cooling channels ( ... ...

    Abstract Rapid tooling technology (RTT) provides an alternative approach to quickly provide wax injection molds for the required products since it can reduce the time to market compared with conventional machining approaches. Removing conformal cooling channels (CCCs) is the key technology for manufacturing injection mold fabricated by rapid tooling technology. In this study, three different kinds of materials were used to fabricate CCCs embedded in the injection mold. This work explores a technology for rapid development of injection mold with high cooling performance. It was found that wax is the most suitable material for making CCCs. An innovative method for fabricating a large intermediary mold with both high load and supporting capacities for manufacturing a large rapid tooling using polyurethane foam was demonstrated. A trend equation for predicting the usage amount of polyurethane foam was proposed. The production cost savings of about 50% can be obtained. An optimum conformal cooling channel design obtained by simulation is proposed. Three injection molds with different cooling channels for injection molding were fabricated by RTT. Reductions in the cooling time by about 89% was obtained. The variation of the results between the experiment and the simulation was investigated and analyzed.
    Language English
    Publishing date 2021-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi12030311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A developmental switch between electrical and neuropeptide communication in the ventromedial hypothalamus.

    Shao, Yin-Qi / Fan, Liu / Wu, Wen-Yan / Zhu, Yi-Jun / Xu, Hua-Tai

    Current biology : CB

    2022  Volume 32, Issue 14, Page(s) 3137–3145.e3

    Abstract: Dissecting neural connectivity patterns within local brain regions is an essential step to understanding the function of the brain. ...

    Abstract Dissecting neural connectivity patterns within local brain regions is an essential step to understanding the function of the brain.
    MeSH term(s) Animals ; Cell Communication ; Hypothalamic Area, Lateral/physiology ; Hypothalamus/physiology ; Neurons/physiology ; Neuropeptides ; Ventromedial Hypothalamic Nucleus/physiology
    Chemical Substances Neuropeptides
    Language English
    Publishing date 2022-06-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1071731-6
    ISSN 1879-0445 ; 0960-9822
    ISSN (online) 1879-0445
    ISSN 0960-9822
    DOI 10.1016/j.cub.2022.05.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Fast-adaptive color-collaborative constellation designs for multicolor multiple-input multiple-output visible light communications systems.

    Xiao, Ye / Zhu, Yi-Jun / Zhang, Yan-Yu / Sun, Zheng-Guo

    Applied optics

    2019  Volume 58, Issue 6, Page(s) 1433–1441

    Abstract: A fast-adaptive color-collaborative signal constellation (CCSC) is proposed for chromaticity-changeable multicolor multiple-input multiple-output (MIMO) visible light communications (VLC) systems. The design of CCSC aims at developing the constellation ... ...

    Abstract A fast-adaptive color-collaborative signal constellation (CCSC) is proposed for chromaticity-changeable multicolor multiple-input multiple-output (MIMO) visible light communications (VLC) systems. The design of CCSC aims at developing the constellation to minimize the average optical power with shaping-based lattice code. For multicolor VLC signals, we arrive at the fact that the optimum shape of the constellation bounding region is an inequilateral N-D simplex. With the densest lattice-packing structure, detailed design steps of CCSC are fully elaborated by lattice construction, effective point selection, and chromaticity adjustment. As CCSC has a low complexity, its constellation structure can adapt quickly to changeable chromaticity demands. Simulation results show that the performance of CCSC is better than enhanced standard color shift keying (CSK) and is close to iterative CSK modulation based on numerical search.
    Language English
    Publishing date 2019-03-15
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.58.001433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Adaptive spatial-layout selection for massive multi-color visible light communications.

    Zhang, Yumeng / Zhu, Yi-Jun / Zhang, Yan-Yu / Chao, Wang

    Applied optics

    2019  Volume 58, Issue 36, Page(s) 9786–9796

    Abstract: Massive multi-color visible light communications (mMC-VLC) sufficiently utilizing space and color domain resources is proposed to satisfy high-spectral-efficiency, high-speed, and high-density-coverage requirements of next-generation indoor data ... ...

    Abstract Massive multi-color visible light communications (mMC-VLC) sufficiently utilizing space and color domain resources is proposed to satisfy high-spectral-efficiency, high-speed, and high-density-coverage requirements of next-generation indoor data connections. However, the gap between the number of LEDs and photodiodes (PDs) and the high correlation among different channels limit the multiplexing of mMC-VLC. Also, the mobility of the receiver is the bottleneck of mMC-VLC. So, adaptive spatial-layout selection (ASLS) is proposed to settle the above problems, which selects $ N $N sets $ n $n-color LEDs from the transmitter to form an approximate optimal closed-circle layout adapting to the receiver position. First, the optimal parameter problems to minimize the ill condition of the activated system under layout constraints of the closed circle and linear types are formulated for a fixed receiver position. Second, to achieve adaptivity, the fitting curves of the optimal layout parameter and $ {D_v} $D
    Language English
    Publishing date 2019-12-23
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.58.009786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Efficient signal design and optimal power allocation for visible light communication attocell systems.

    Sun, Zheng-Guo / Yu, Hongyi / Zhu, Yi-Jun

    Applied optics

    2017  Volume 56, Issue 32, Page(s) 8959–8968

    Abstract: In this paper, we investigate visible light communication (VLC) attocell systems in which any two neighboring attocells overlap. An efficient signal design for VLC called time superposition reuse (TSR) is proposed to mitigate interference and improve ... ...

    Abstract In this paper, we investigate visible light communication (VLC) attocell systems in which any two neighboring attocells overlap. An efficient signal design for VLC called time superposition reuse (TSR) is proposed to mitigate interference and improve spectral efficiency. In the scheme, two neighboring cells are allocated with two time slots that have superposition in the time domain. By adjusting superposition between time slots, the system can achieve a flexible spectral efficiency and system performance. Further, we develop an optimal power allocation strategy for TSR in the system. The strategy is given according to the position of the user and the level of superposition, and then the corresponding optimal Euclidean distance is derived. In addition, we analyze the system performance and prove that the optimal Euclidean distance is an increasing function of the delay between signals and a decreasing function of the sampling period. Simulation results demonstrate that the optimal power allocation has a better performance than uniform power allocation and TSR outperforms time division multiple access significantly for the user in VLC attocell systems.
    Language English
    Publishing date 2017-11-10
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.56.008959
    Database MEDical Literature Analysis and Retrieval System OnLINE

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