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  1. Article: Longitudinal relationship between internet self-control and problematic internet use among Chinese adolescents: mediating role of meaning in life.

    Wang, Weijun / Ye, Jianmei / Zhu, Yimeng / Huang, Dawei / Zhao, Xin

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1258673

    Abstract: Introduction: While studies indicate that high self-control may serve as a safeguard against problematic internet use, there's evidence suggesting that problematic internet use can, in turn, diminish self-control. This study aimed to elucidate the ... ...

    Abstract Introduction: While studies indicate that high self-control may serve as a safeguard against problematic internet use, there's evidence suggesting that problematic internet use can, in turn, diminish self-control. This study aimed to elucidate the longitudinal interplay between internet self-control and problematic internet use in adolescents, employing cross-lagged panel modeling. Furthermore, drawing from a positive psychology perspective, we examined the potential role of 'meaning in life' as a protective mediator within this longitudinal relationship. We then constructed a mediation model to explore protective factors against problematic internet use.
    Methods: Through a questionnaire, we tracked 659 adolescents (331 males and 328 females; mean age=13.61) in a longitudinal design across two time points, spaced at five-month intervals, to assess their internet self-control, problematic internet use, and meaning in life.
    Results: Results of the cross-lagged panel models showed that: Internet self-control had a significant negative impact on problematic internet use after five months (
    Conclusion: Our study uncovers a reciprocal predictive relationship between internet self-control and problematic internet use, while highlighting the mediating role of meaning in life within this relationship. These findings suggest that fostering internet self-control and cultivating a sense of meaning in life among adolescents can serve as effective prevention and intervention strategies for addressing the issue of problematic internet use.
    Language English
    Publishing date 2023-12-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1258673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Compact generation of robust Airy beam pattern with spatial coherence engineering.

    Zhu, Yimeng / Dong, Zhen / Wang, Fei / Chen, Yahong / Cai, Yangjian

    Optics letters

    2022  Volume 47, Issue 11, Page(s) 2846–2849

    Abstract: We present a class of partially coherent light sources having Airy-type amplitude and Airy-correlated spatial coherence. We show that the light beam generated by such sources can preserve the Airy beam pattern well during its propagation from source to ... ...

    Abstract We present a class of partially coherent light sources having Airy-type amplitude and Airy-correlated spatial coherence. We show that the light beam generated by such sources can preserve the Airy beam pattern well during its propagation from source to far field. We demonstrate the robustness of the Airy beam pattern by introducing a hard aperture to largely block the beam source. We find that the coherence-induced Airy beam pattern can still be well reconstructed during propagation. We successfully synthesize such partially coherent source using the principle of complex random modes decomposition by using a single phase-only spatial light modulator. The proposed robust Airy beam pattern may find applications in information transmission through complex media.
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.460191
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The plié by DNA-PK: dancing on DNA.

    Zha, Shan / Shao, Zhengping / Zhu, Yimeng

    Molecular cell

    2021  Volume 81, Issue 4, Page(s) 644–646

    Abstract: In this issue of Molecular Cell, Chen et al. (2020) report the structural transition during DNA-dependent activation of DNA-PK, shedding light on the mechanism by which kinase inhibitors and auto-phosphorylation-deficient DNA-PKcs compromise non- ... ...

    Abstract In this issue of Molecular Cell, Chen et al. (2020) report the structural transition during DNA-dependent activation of DNA-PK, shedding light on the mechanism by which kinase inhibitors and auto-phosphorylation-deficient DNA-PKcs compromise non-homologous end-joining (Chen et al., 2020).
    MeSH term(s) DNA/genetics ; DNA End-Joining Repair ; DNA-Activated Protein Kinase/genetics ; DNA-Activated Protein Kinase/metabolism ; DNA-Binding Proteins/metabolism ; Ku Autoantigen/metabolism ; Nuclear Proteins/metabolism ; Phosphorylation
    Chemical Substances DNA-Binding Proteins ; Nuclear Proteins ; DNA (9007-49-2) ; DNA-Activated Protein Kinase (EC 2.7.11.1) ; Ku Autoantigen (EC 4.2.99.-)
    Language English
    Publishing date 2021-03-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2021.01.025
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  4. Article ; Online: Correction to: Association of metformin treatment with enhanced effect of anti‑VEGF agents in diabetic macular edema patients.

    Shao, Yan / Wang, Manqiao / Zhu, Yimeng / Li, Xiaorong / Liu, Juping

    Acta diabetologica

    2022  Volume 59, Issue 4, Page(s) 561

    Language English
    Publishing date 2022-02-03
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1097676-0
    ISSN 1432-5233 ; 0940-5429
    ISSN (online) 1432-5233
    ISSN 0940-5429
    DOI 10.1007/s00592-022-01849-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Association of metformin treatment with enhanced effect of anti-VEGF agents in diabetic macular edema patients.

    Shao, Yan / Wang, Manqiao / Zhu, Yimeng / Li, Xiaorong / Liu, Juping

    Acta diabetologica

    2022  Volume 59, Issue 4, Page(s) 553–559

    Abstract: Purpose: To investigate the effect of metformin combined with anti-VEGF agents in patients with diabetic macular edema (DME).: Methods: This study was a prospective, nonrandomized case-control study. Patients were included in with a diagnosis of DME ... ...

    Abstract Purpose: To investigate the effect of metformin combined with anti-VEGF agents in patients with diabetic macular edema (DME).
    Methods: This study was a prospective, nonrandomized case-control study. Patients were included in with a diagnosis of DME who received anti-VEGF agents injection. Basic information, medical history, best-corrected visual acuity (BCVA), central macular thickness (CMT), the number of intravitreal injections, panretinal photocoagulation (PRP), and macular grid photocoagulation treatment during the 6-month follow-up, were recorded for each patient.
    Results: A total of 50 DME patients were collected (24 patients with a history of oral metformin ≥ 6 months and 26 patients who had not taken metformin). The BCVA and the CMT were significantly improved after anti-VEGF treatment in two groups (F1 = 19.35, F2 = 26.78; F1 = 65.45, F2 = 76.23; P < 0.05). The BCVA in the metformin group was better than that in non-metformin group at every point after treatment (F = 34.45, P < 0.05). The CMT in metformin group decreased much more than that in non-metformin group during the follow-up period (F = 87.05, P < 0.05). The injection numbers decreased in the metformin group compared with the non-metformin group (t = 5.14, P < 0.05). However, there was no difference in PRP and macular grid photocoagulation therapy between the two groups during the 6-month follow-up.
    Conclusion: Metformin can enhance the therapeutic effect of anti-VEGF agents on DME patients to improve their visual acuity, improve the structure of the macular area, and reduce the number of intravitreal injections 90.
    MeSH term(s) Angiogenesis Inhibitors/therapeutic use ; Case-Control Studies ; Diabetes Mellitus/drug therapy ; Diabetic Retinopathy/complications ; Diabetic Retinopathy/diagnosis ; Diabetic Retinopathy/drug therapy ; Humans ; Intravitreal Injections ; Macular Edema/diagnosis ; Macular Edema/drug therapy ; Macular Edema/etiology ; Metformin/therapeutic use ; Prospective Studies ; Tomography, Optical Coherence ; Treatment Outcome
    Chemical Substances Angiogenesis Inhibitors ; Metformin (9100L32L2N)
    Language English
    Publishing date 2022-01-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1097676-0
    ISSN 1432-5233 ; 0940-5429
    ISSN (online) 1432-5233
    ISSN 0940-5429
    DOI 10.1007/s00592-021-01833-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Colorimetric Sensing of the Peroxide Number of Milk Powder Using CsPbBr

    Zhang, Li / Zhu, Yimeng / Guo, Zhiyong / You, Longjie / Zhang, Chen / Chen, Xi

    Biosensors

    2023  Volume 13, Issue 4

    Abstract: In this study, a wavelength-shift-based colorimetric sensing approach for the peroxide number of milk powder using ... ...

    Abstract In this study, a wavelength-shift-based colorimetric sensing approach for the peroxide number of milk powder using CsPbBr
    MeSH term(s) Animals ; Peroxides ; Powders ; Colorimetry ; Milk ; Nanoparticles
    Chemical Substances perovskite (12194-71-7) ; Peroxides ; Powders
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios13040493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Phosphorylation of DNA-PKcs at the S2056 cluster ensures efficient and productive lymphocyte development in XLF-deficient mice.

    Zhu, Yimeng / Jiang, Wenxia / Lee, Brian J / Li, Angelina / Gershik, Steven / Zha, Shan

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 25, Page(s) e2221894120

    Abstract: The nonhomologous end-joining (NHEJ) pathway is a major DNA double-strand break repair pathway in mammals and is essential for lymphocyte development. Ku70 and Ku80 heterodimer (KU) initiates NHEJ, thereby recruiting and activating the catalytic subunit ... ...

    Abstract The nonhomologous end-joining (NHEJ) pathway is a major DNA double-strand break repair pathway in mammals and is essential for lymphocyte development. Ku70 and Ku80 heterodimer (KU) initiates NHEJ, thereby recruiting and activating the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs). While DNA-PKcs deletion only moderately impairs end-ligation, the expression of kinase-dead DNA-PKcs completely abrogates NHEJ. Active DNA-PK phosphorylates DNA-PKcs at two clusters-PQR around S2056 (S2053 in mouse) and ABCDE around T2609. Alanine substitution at the S2056 cluster moderately compromises end-ligation on plasmid-based assays. But, mice carrying alanine substitution at all five serine residues within the S2056 cluster (
    MeSH term(s) Animals ; Mice ; Phosphorylation ; Protein Kinases ; Protein Processing, Post-Translational ; Alanine ; B-Lymphocytes ; DNA-Activated Protein Kinase ; Mammals ; DNA-Binding Proteins
    Chemical Substances Protein Kinases (EC 2.7.-) ; Alanine (OF5P57N2ZX) ; DNA-Activated Protein Kinase (EC 2.7.11.1) ; XLF protein, mouse ; DNA-Binding Proteins
    Language English
    Publishing date 2023-06-12
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2221894120
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  8. Article ; Online: The Role and Mechanism of Hydrogen-Rich Water in the

    Wang, Xue / An, Zhonghui / Liao, Jiameng / Ran, Nana / Zhu, Yimeng / Ren, Shufeng / Meng, Xiangnan / Cui, Na / Yu, Yang / Fan, Haiyan

    International journal of molecular sciences

    2023  Volume 24, Issue 7

    Abstract: Cucumber is a warm climate vegetable that is sensitive to chilling reactions. Chilling can occur at any period of cucumber growth and development and seriously affects the yield and quality of cucumber. Hydrogen ( ... ...

    Abstract Cucumber is a warm climate vegetable that is sensitive to chilling reactions. Chilling can occur at any period of cucumber growth and development and seriously affects the yield and quality of cucumber. Hydrogen (H
    MeSH term(s) Cucumis sativus/metabolism ; Hydrogen Peroxide/metabolism ; Antioxidants/metabolism ; Hydrogen/metabolism ; Water/metabolism ; Superoxide Dismutase/metabolism ; Seedlings/metabolism
    Chemical Substances Hydrogen Peroxide (BBX060AN9V) ; Antioxidants ; Hydrogen (7YNJ3PO35Z) ; Water (059QF0KO0R) ; Superoxide Dismutase (EC 1.15.1.1)
    Language English
    Publishing date 2023-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24076702
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  9. Article ; Online: CDK14 expression is elevated in patients with non-small cell lung cancer and correlated with poor prognosis.

    Yang, Yong / Yuan, Guangda / Xie, Hongya / Wei, Tengteng / Zhu, Donglin / Zhu, Yimeng / Zheng, Shiying

    publication RETRACTED

    The Journal of international medical research

    2021  Volume 49, Issue 10, Page(s) 3000605211013199

    Abstract: Objective: To investigate the clinical significance of cyclin-dependent kinase 14 (CDK14) expression in patients with non-small cell lung cancer (NSCLC).: Methods: The present prospective observational study included 193 patients diagnosed with NSCLC ...

    Abstract Objective: To investigate the clinical significance of cyclin-dependent kinase 14 (CDK14) expression in patients with non-small cell lung cancer (NSCLC).
    Methods: The present prospective observational study included 193 patients diagnosed with NSCLC between January 2010 and December 2014. NSCLC tumor tissues and paired paracancerous normal tissues were obtained from all patients. CDK14, thyroid transcription factor 1 (TTF-1), cytokeratin 5/6 (CK5/6), and Ki67 expression was measured
    Results: CDK14 staining was strong (>3) in 129 patients (66.49%) and weak (≤3) in 64 patients (33.16%). The mean IHC scores were markedly higher in tumor tissues than in paracancerous tissues. Pearson's analysis demonstrated that the IHC scores of CDK14 expression were positively correlated with TTF-1, CK5/6, and Ki67 scores. Kaplan-Meier analysis illustrated that 5-year overall survival was markedly longer in patients with weak CDK14 staining. TNM stage, pleural invasion, lymph node metastasis, CDK14 expression, and Ki67 expression were risk factors for 5-year overall survival in patients with NSCLC.
    Conclusion: CDK14 overexpression portended poor outcomes in patients with NSCLC, and CDK14 expression was correlated with TTF-1, CK5/5, and Ki67 expression.
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/diagnosis ; Carcinoma, Non-Small-Cell Lung/genetics ; Cyclin-Dependent Kinases ; Humans ; Immunohistochemistry ; Lung Neoplasms/diagnosis ; Lung Neoplasms/genetics ; Lymphatic Metastasis ; Prognosis
    Chemical Substances CDK14 protein, human (EC 2.7.11.22) ; Cyclin-Dependent Kinases (EC 2.7.11.22)
    Language English
    Publishing date 2021-10-08
    Publishing country England
    Document type Journal Article ; Observational Study ; Retracted Publication
    ZDB-ID 184023-x
    ISSN 1473-2300 ; 0300-0605 ; 0142-2596
    ISSN (online) 1473-2300
    ISSN 0300-0605 ; 0142-2596
    DOI 10.1177/03000605211013199
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  10. Article ; Online: Colorimetric sensing of chloride in sweat based on fluorescence wavelength shift via halide exchange of CsPbBr

    Li, Feiming / Feng, Yufeng / Huang, Yipeng / Yao, Qiuhong / Huang, Guihua / Zhu, Yimeng / Chen, Xi

    Mikrochimica acta

    2021  Volume 188, Issue 1, Page(s) 2

    Abstract: Considering the high importance of the rapid detection of chloride ion ( ... ...

    Abstract Considering the high importance of the rapid detection of chloride ion (Cl
    MeSH term(s) Bromides/chemistry ; Cesium/chemistry ; Chlorides/analysis ; Colorimetry/methods ; Fluorescent Dyes/chemistry ; Humans ; Lead/chemistry ; Nanoparticles/chemistry ; Spectrometry, Fluorescence/methods ; Sweat/chemistry
    Chemical Substances Bromides ; Chlorides ; Fluorescent Dyes ; Cesium (1KSV9V4Y4I) ; Lead (2P299V784P)
    Language English
    Publishing date 2021-01-02
    Publishing country Austria
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 89-9
    ISSN 1436-5073 ; 0026-3672
    ISSN (online) 1436-5073
    ISSN 0026-3672
    DOI 10.1007/s00604-020-04653-5
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