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Article: Unilateral Biportal Endoscopy for the Resection of Thoracic Intradural Extramedullary Tumors: Technique Case Report and Literature Review.

Peng, Wei / Zhuang, Yin / Cui, Wei / Chen, Wenjin / Chu, Rupeng / Sun, Zhenzhong / Zhang, Shujun

International medical case reports journal

2024 Volume 17, Page(s) 301–309

Abstract: This study describes a patient with an intradural extramedullary (IDEM) tumor removed entirely using the unilateral biportal endoscopic technique (UBE), achieving satisfactory clinical outcomes. A 60-year-old woman had a diagnosis of meningioma with ... ...

Abstract	This study describes a patient with an intradural extramedullary (IDEM) tumor removed entirely using the unilateral biportal endoscopic technique (UBE), achieving satisfactory clinical outcomes. A 60-year-old woman had a diagnosis of meningioma with sensations and motor dysfunction in the lower extremities and perineum and gait disturbances for three years, which has worsened over the last month. Preoperative imaging data showed a sizeable IDEM tumor at the T10 level, significantly compressing the thoracic spinal cord to the right side, with 80% intraspinal encroachment. The IDEM tumor was removed entirely by UBE surgery. To the best of our knowledge, this study may be the first to report the application of UBE techniques for IDEM tumor treatment. In this case, UBE provides a magnified and clear surgical field, greater maneuverability, and a less invasive surgical procedure. The procedure objectives were pathological confirmation, spinal cord decompression, and complete tumor removal; all were met. The patient was satisfied with her dramatically improved clinical symptoms. UBE may be an alternative surgical treatment option for benign IDEM tumors presenting with symptomatic, especially the non-giant lateral and posterior tumors.
Language	English
Publishing date	2024-04-09
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495077-4
ISSN	1179-142X
ISSN	1179-142X
DOI	10.2147/IMCRJ.S444226
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Survey of Affective-Based Dialogue System

ZHUANG Yin, LIU Zhen, LIU Tingting, WANG Yuanyi, LIU Cuijuan, CHAI Yanjie

Jisuanji kexue yu tansuo, Vol 15, Iss 5, Pp 825-

2021 Volume 837

Abstract: As an important way of human-computer interaction, the dialogue system has broad application prospects. Existing dialogue systems focus on solving problems such as semantic consistency and content richness and paying little attention to improving human- ... ...

Abstract	As an important way of human-computer interaction, the dialogue system has broad application prospects. Existing dialogue systems focus on solving problems such as semantic consistency and content richness and paying little attention to improving human-computer interaction and human-computer resonance. How to make the generated sentences communicate with users more naturally on the basis of semantic relevance is one of the main problems in current dialogue system. First, it summarizes the overall situation of the dialogue system. Then it introduces the two major tasks of dialogue emotion perception and emotional dialogue generation in the emotional dialogue system. And further it investigates and summarizes related methods respectively. Dialogue emotion perception tasks are roughly divided into context-based and user-based methods. The emotional dialogue generation methods include rule matching algorithms, specified emotional response generation models, and non-specified emotional response generation models. The models are compared and analyzed in terms of emotional data categories and model methods. Next, for subsequent research, it summarizes characteristics and links of the data sets under the two major tasks. Further, different evaluation methods in the current emotional dialogue system are summarized. Finally, the work of the emotional dialogue system is summarized and prospected.
Keywords	emotional dialogue system ; dialogue emotional perception ; generation of emotional dialogue ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	200
Language	Chinese
Publishing date	2021-05-01T00:00:00Z
Publisher	Journal of Computer Engineering and Applications Beijing Co., Ltd., Science Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: EarthGPT

Zhang, Wei / Cai, Miaoxin / Zhang, Tong / Zhuang, Yin / Mao, Xuerui

A Universal Multi-modal Large Language Model for Multi-sensor Image Comprehension in Remote Sensing Domain

2024

Abstract: Multi-modal large language models (MLLMs) have demonstrated remarkable success in vision and visual-language tasks within the natural image domain. Owing to the significant diversities between the natural image and RS image hinder the development of ... ...

Abstract	Multi-modal large language models (MLLMs) have demonstrated remarkable success in vision and visual-language tasks within the natural image domain. Owing to the significant diversities between the natural image and RS image hinder the development of MLLMs in the remote sensing (RS) domain. Currently, the unified and powerful MLLM capable of various RS visual tasks is still under-explored. To fill the gap, a pioneer MLLM called EarthGPT is proposed for universal RS image comprehension, which integrates various multi-sensor RS interpretation tasks uniformly. More importantly, a large-scale multi-sensor multi-modal RS instruction-following dataset named MMRS is carefully constructed, which comprises 1005.842k image-text pairs based on 34 existing diverse RS datasets and includes multi-sensor images such as optical, synthetic aperture radar (SAR), and infrared. The MMRS addresses the issue of MLLMs lacking RS expert knowledge and stimulates the development of MMLMs in the RS domain. Extensive experiments demonstrate the EarthGPT's superior performance in various RS visual interpretation tasks compared with the other specialist models and MLLMs, which proves the effectiveness of the proposed EarthGPT and provides a versatile paradigm for open-set reasoning tasks.
Keywords	Computer Science - Computer Vision and Pattern Recognition
Subject code	004
Publishing date	2024-01-30
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: In vivo effects of low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring.

Zhuang, Yin / Sun, Xiangying / Deng, Siting / Wen, Ya / Xu, Qiujin / Guan, Quanquan

Ecotoxicology and environmental safety

2023 Volume 257, Page(s) 114946

Abstract: Background: Bisphenol A (BPA) is known to exhibit endocrine disrupting activities and is associated with adiposity. We examined the obesogenic effect of prenatal BPA exposure in the present study.: Methods: Pregnant ICR mice were exposed to vehicle ... ...

Abstract	Background: Bisphenol A (BPA) is known to exhibit endocrine disrupting activities and is associated with adiposity. We examined the obesogenic effect of prenatal BPA exposure in the present study. Methods: Pregnant ICR mice were exposed to vehicle or BPA via the drinking water at a dose of 0.5 μg/kg·d throughout the gestation. Obesity-related indexes were investigated in the 12-wk-old offspring. Primary mouse embryonic fibroblasts (MEFs) collected from treated embryos were used to test effects of BPA on adipocyte differentiation. Results: Offspring presented a significantly higher rate of weight gain than the control, with impaired insulin sensitivity and increased adipocyte size. Differentiation of MEFs from BPA-treated mice showed a higher propensity for the adipocyte commitment as well as up-regulation of genes enriched in lipid biosynthesis. TGF-β signaling pathway was found to modulate obesogenic effect of BPA in MEF model, but estrogen signaling pathway had no effect. Conclusions: The present study provides strong evidence of the association between prenatal exposure to low dose of BPA and a significant increase in body weight in the offspring mice with a critical role played by TGF-β signaling pathway. The potential interactions modulating the binding of BPA and TGF-β that activate its obesogenic effects need to be examined.
MeSH term(s)	Pregnancy ; Humans ; Animals ; Male ; Mice ; Female ; Adiposity ; Prenatal Exposure Delayed Effects/chemically induced ; Mice, Inbred ICR ; Fibroblasts ; Obesity ; Benzhydryl Compounds/toxicity
Chemical Substances	bisphenol A (MLT3645I99) ; Benzhydryl Compounds
Language	English
Publishing date	2023-04-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	436536-7
ISSN	1090-2414 ; 0147-6513
ISSN (online)	1090-2414
ISSN	0147-6513
DOI	10.1016/j.ecoenv.2023.114946
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Article: Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.

Chen, Wen-Jin / Zhuang, Yin / Peng, Wei / Cui, Wei / Zhang, Shu-Jun / Wang, Jian-Wei

Chinese medicine

2023 Volume 18, Issue 1, Page(s) 80

Abstract: Background: Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand years, but its mechanism for ... ...

Abstract	Background: Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand years, but its mechanism for treating KOA has not been revealed. In our previous study, we confirmed that DHJST inhibited the activation of NLRP3 signaling in rats and humans. In the current study, we aimed to determine how DHJST inhibits NLRP3 to alleviate knee cartilage damage. Methods: Mice were injected with NLRP3 shRNA or Notch1-overexpressing adenovirus into the tail vein to construct systemic NLRP3 low-expressing or Notch1 high-expressing mice. Mice were injected with papain into the knee joint to replicate the KOA model. DHJST was used to treat KOA model mice with different backgrounds. The thickness of the right paw was measured to evaluate toe swelling. The pathohistological changes and the levels of IL-1β, MMP2, NLRP3, Notch1, collagen 2, collagen 4, HES1, HEY1, and Caspase3 were detected by HE staining, ELISA, immunohistochemical staining, western blotting, or real-time qPCR. Results: DHJST reduced tissue swelling and serum and knee cartilage IL-1β levels, inhibited cartilage MMP2 expression, increased collagen 2 and collagen 4 levels, decreased Notch1 and NLRP3 positive expression rates in cartilage, and decreased HES1 and HEY1 mRNA levels in KOA model mice. In addition, NLRP3 interference decreased cartilage MMP2 expression and increased collagen 2 and collagen 4 levels without affecting the expression levels of notch1, HES1 and HEY1 mRNA levels in the synovium of KOA mice. In KOA mice with NLRP interference, DHJST further reduced tissue swelling and knee cartilage damage in mice. Finally, Notch1-overexpressing mice not only showed more severe tissue swelling and knee cartilage degradation but also abolished the therapeutic effect of DHJST on KOA mice. Importantly, the inhibitory effects of DHJST on the mRNA expression of NLRP3, Caspase3 and IL-1β in the knee joint of KOA mice were completely limited after Notch1 overexpression. Conclusion: DHJST significantly reduced inflammation and cartilage degradation in KOA mice by inhibiting Ntoch1 signaling and its subsequent NLRP3 activation in the knee joint.
Language	English
Publishing date	2023-06-29
Publishing country	England
Document type	Journal Article
ZDB-ID	2260322-0
ISSN	1749-8546
ISSN	1749-8546
DOI	10.1186/s13020-023-00784-y
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Article ; Online: Correction: Inflammatory myofibroblastic tumor of the thigh without bone involvement: a case report.

Lin, Jun / Liu, Hao / Zhuang, Yin / Yang, Peng / Zheng, Yifei / Yang, Yan / Yang, Huilin

World journal of surgical oncology

2023 Volume 21, Issue 1, Page(s) 278

Language	English
Publishing date	2023-09-05
Publishing country	England
Document type	Published Erratum
ZDB-ID	2118383-1
ISSN	1477-7819 ; 1477-7819
ISSN (online)	1477-7819
ISSN	1477-7819
DOI	10.1186/s12957-023-03158-8
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Article ; Online: Clinical efficacy and safety of targeted injection of PRP with skin booster in the treatment of aging face.

Shen, Jinwen / Yu, Xia / Zhuang, Yin / Kong, Yuwei / Zhao, Jingjun / Yao, Zhirong

Biotechnology & genetic engineering reviews

2023 , Page(s) 1–17

Abstract: Platelet-rich plasma (PRP) with skin booster is a popular treatment for improving skin quality and reducing the signs of aging. However, few studies have evaluated its clinical efficacy in patients with aging face. This study aimed to evaluate the ... ...

Abstract	Platelet-rich plasma (PRP) with skin booster is a popular treatment for improving skin quality and reducing the signs of aging. However, few studies have evaluated its clinical efficacy in patients with aging face. This study aimed to evaluate the clinical efficacy, adverse reactions, and follow-up results of targeted injection of PRP with skin booster in treating patients with aging face. The study included 80 patients treated with targeted injection of PRP with skin booster from July 2022 to February 2023. The doctors compared the changes of the patients' facial skin indicators, quality of life, and satisfaction with their appearance before and after treatment, and analyzed the clinical efficacy, adverse reactions, and follow-up results of the patients after treatment. After one course of treatment, the patients' facial skin indicators, quality of life, and satisfaction with their appearance improved significantly, with
Language	English
Publishing date	2023-04-10
Publishing country	England
Document type	Journal Article
ZDB-ID	49457-4
ISSN	2046-5556 ; 0264-8725
ISSN (online)	2046-5556
ISSN	0264-8725
DOI	10.1080/02648725.2023.2199233
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Article ; Online: Retraction notice to "Role of microRNA-15a-5p/Sox9/NF-κB axis in inflammatory factors and apoptosis of murine nucleus pulposus cells in intervertebral disc degeneration" [Life Sci. 277 (2021) 119408].

Zhang, Shujun / Song, Sheng / Zhuang, Yin / Hu, Jun / Cui, Wei / Wang, Xin / Zhao, Zhigang / Liu, Xueguang / Sun, Zhenzhong

Life sciences

2023 Volume 325, Page(s) 121731

Language	English
Publishing date	2023-05-11
Publishing country	Netherlands
Document type	Journal Article ; Retraction of Publication
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2023.121731
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Article: Understanding the relationship between microstructure and mechanical behavior of plasma-sprayed amorphous Al2O3–YAG ceramic coating based on depth-sensing indentation measurements

Yang, Kai / Ai, Yizhaotong / Qiang, Linya / Zhang, Xiaozhen / Zhuang, Yin / Sheng, Jing / Ni, Jinxing / Ding, Chuanxian

Journal of materials science. 2022 Aug., v. 57, no. 31

2022

Abstract: Based on depth-sensing indentation measurements, the relationship between microstructure and mechanical behavior of plasma-sprayed amorphous Al₂O₃–YAG ceramic coating was investigated. The Al₂O₃ and Al₂O₃–Y₂O₃ coatings were also deposited for performance ...

Abstract	Based on depth-sensing indentation measurements, the relationship between microstructure and mechanical behavior of plasma-sprayed amorphous Al₂O₃–YAG ceramic coating was investigated. The Al₂O₃ and Al₂O₃–Y₂O₃ coatings were also deposited for performance comparison and mechanism discussion. In nanoindentation tests, the load-control mode was selected. Constant loading rate/load (P′/P) method was applied to obtain the steady-state indentation process by control loading. Scanning electron microscope, electron backscatter diffraction, depth-sensing indentation method of Oliver and Pharr, Weertman–Dorn equation and elastic–viscoelastic–viscous (EVEV) model were combined to analyze microstructural features, phase distribution and nanomechanical behavior of the coatings. The results revealed that amorphous Al₂O₃–YAG coating possessed excellent microstructure/mechanical performance uniformity, larger recovery resistance Rₛ, higher fraction of energy dissipation rd and better creep performance. Compared with the Al₂O₃ and Al₂O₃–Y₂O₃ coatings, the Al₂O₃–YAG coating showed a significant increase in creep compliance, which denoted corresponding decrease in coating elastic modulus and reflected more pronounced relaxation phenomenon.
Keywords	X-ray diffraction ; ceramics ; energy ; equations ; mechanical properties ; microstructure ; models ; modulus of elasticity
Language	English
Dates of publication	2022-08
Size	p. 14681-14698.
Publishing place	Springer US
Document type	Article
ZDB-ID	2015305-3
ISSN	1573-4803 ; 0022-2461
ISSN (online)	1573-4803
ISSN	0022-2461
DOI	10.1007/s10853-022-07585-y
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Estimating the effects of policies on infertility prevalence worldwide.

Zhang, Xiaochen / Guan, Quanquan / Yu, Qiurun / Xiao, Wenwen / Chen, Ziyu / Dong, Chao / Deng, Siting / Zhuang, Yin / Xia, Yankai

BMC public health

2022 Volume 22, Issue 1, Page(s) 1378

Abstract: Background: Infertility has troubled millions of people worldwide while always being an ignored issue. The high cost of treatment or lack of services placed a barrier to the alleviation of infertility status. Governments play a significant role to ... ...

Abstract	Background: Infertility has troubled millions of people worldwide while always being an ignored issue. The high cost of treatment or lack of services placed a barrier to the alleviation of infertility status. Governments play a significant role to promote infertility-related policies for better access to infertility services and comprehensive supports for infertile people. Methods: Data of infertility status indicators and infertility-related policies in ten representative countries were collected. An infertility-related policy system was established, then classification and quantification were processed according to specific criteria, and different policy implementation patterns were identified. The effectiveness of specific infertility-related policy and various patterns on infertility prevalence relief between 1990 and 2017 were evaluated via generalized linear models and analyses of covariance for the first time. Results: Economic support policies would be less prioritized compared with social security policies, while economic support policy had a significant positive role in the decline of female infertility prevalence (β = -2·16, p = 0·042). In detail, insurance coverage and economic reward policies were crucial (β = -3·31, p = 0·031; β = -4·10, p = 0·025) with adjusted with covariates. The effect of economic support-oriented pattern was relatively better than other patterns for both male and female infertility prevalence relief. Nevertheless, the effectiveness of gradual-promotion pattern seemed preferable for male infertility prevalence relief while was similar with simultaneous-promotion pattern for females. Conclusions: Our data-driven analysis revealed that insurance coverage and economic reward policies played the pivotal role in moderation of female infertility status. Economic support-oriented pattern and gradual-promotion pattern were preferable when promoting infertility-related policies.
MeSH term(s)	Female ; Humans ; Infertility, Female ; Insurance Coverage ; Male ; Policy ; Prevalence
Language	English
Publishing date	2022-07-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-022-13802-9
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