Article: [Oncological results of repeat partial nephrectomy in patients with recurrence after nephron-sparing procedures].
Urologiia (Moscow, Russia : 1999)
2024 , Issue 1, Page(s) 86–91
Abstract: Aim: To carried out a comparative analysis of the risk of complications and oncological results of repeat partial nephrectomy and radical nephrectomy in patients with local recurrence after previous organ-sparing procedures.: Materials and methods: ... ...
| Abstract | Aim: To carried out a comparative analysis of the risk of complications and oncological results of repeat partial nephrectomy and radical nephrectomy in patients with local recurrence after previous organ-sparing procedures. Materials and methods: Retrospective and prospective data of 64 patients with local recurrence of kidney cancer after nephron-sparing procedures. who underwent surgical treatment in the department of oncourology of the National Medical Research Center of Oncology named after N.N. Blokhin in the period from 2000 to 2022. A total of 37 (57.8%) patients of the main group underwent repeat partial nephrectomy, while in 27 (42.2%) patients in the control group a radical nephrectomy was done. Median follow-up was 35 (3-131; Q1-Q3: 13-57) months. Both groups were comparable in terms of demographic and clinical characteristics (p>0.05). The median time to detect relapse after previous partial nephrectomy was 24 (2-172) months. Results: Complications were noted in 8 (21.6%) patients after repeat partial nephrectomy, compared to 29.6% in the control group (n=8) (p=0.563). A comparative analysis revealed a significant advantage in overall survival in patients of the main group (p=0.042). There were no significant differences between groups in cancer-specific and disease-free survival (p=0.369 and p=0.537, respectively). Conclusion: Repeat partial nephrectomy for local recurrence of kidney cancer leads to an increase in overall survival compared to radical nephrectomy, in the absence of significant differences in cancer-specific and relapse-free survival. |
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| MeSH term(s) | Humans ; Nephrectomy/methods ; Female ; Kidney Neoplasms/surgery ; Kidney Neoplasms/pathology ; Male ; Middle Aged ; Neoplasm Recurrence, Local ; Aged ; Retrospective Studies ; Nephrons/surgery ; Adult ; Organ Sparing Treatments/methods ; Carcinoma, Renal Cell/surgery ; Carcinoma, Renal Cell/pathology ; Prospective Studies | |||||
| Language | Russian | |||||
| Publishing date | 2024-04-22 | |||||
| Publishing country | Russia (Federation) | |||||
| Document type | English Abstract ; Journal Article | |||||
| ZDB-ID | 43204-0 | |||||
| ISSN | 1728-2985 ; 0042-1154 | |||||
| ISSN | 1728-2985 ; 0042-1154 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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