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  1. Article ; Online: How New Developments Will Change Neuroradiology.

    Zimmer, Claus

    Clinical neuroradiology

    2019  Volume 29, Issue 4, Page(s) 593

    MeSH term(s) Humans ; Image Interpretation, Computer-Assisted/methods ; Nervous System Diseases/diagnostic imaging ; Neuroimaging/methods ; Neuroimaging/trends ; Radiology/methods ; Radiology/trends ; Stroke/therapy
    Language English
    Publishing date 2019-11-29
    Publishing country Germany
    Document type Congress ; Editorial
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-019-00856-3
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    Zs.A 3413: Show issues Location:
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  2. Article ; Online: neuroRAD 2022: Precision. Individualized.

    Schramm, Peter / Zimmer, Claus

    Clinical neuroradiology

    2022  Volume 32, Issue 2, Page(s) 323–324

    Language English
    Publishing date 2022-06-10
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-022-01163-0
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  3. Article ; Online: The impact of spectral basis set composition on estimated levels of cingulate glutamate and its associations with different personality traits.

    Demler, Verena F / Sterner, Elisabeth F / Wilson, Martin / Zimmer, Claus / Knolle, Franziska

    BMC psychiatry

    2024  Volume 24, Issue 1, Page(s) 320

    Abstract: Background: 1: Methods: To ensure comparability, we utilized five different exemplar basis sets, used in research, and two different analysis tools, r-based spant applying the ABfit method and Osprey using the LCModel.: Results: Our findings ... ...

    Abstract Background: 1
    Methods: To ensure comparability, we utilized five different exemplar basis sets, used in research, and two different analysis tools, r-based spant applying the ABfit method and Osprey using the LCModel.
    Results: Our findings revealed that the types of metabolites included in the basis set significantly affected the glutamate concentration. We observed that three basis sets led to more consistent results across different concentration types (i.e., absolute Glu in mol/kg, Glx (glutamate + glutamine), Glu/tCr), spectral fit and quality measurements. Interestingly, all three basis sets included phosphocreatine. Importantly, our findings also revealed that glutamate levels were differently associated with both schizotypal and autistic traits depending on basis set configuration and analysis tool, with the same three basis sets showing more consistent results.
    Conclusions: Our study highlights that scientific results may be significantly altered depending on the choices of metabolites included in the basis set, and with that emphasizes the importance of carefully selecting the configuration of the basis set to ensure accurate and consistent results, when using MR spectroscopy. Overall, our study points out the need for standardized analysis pipelines and reporting.
    MeSH term(s) Humans ; Gyrus Cinguli/metabolism ; Glutamic Acid/metabolism ; Male ; Adult ; Female ; Proton Magnetic Resonance Spectroscopy/methods ; Young Adult ; Personality/physiology ; Psychotic Disorders/metabolism ; Magnetic Resonance Spectroscopy/methods ; Glutamine/metabolism
    Chemical Substances Glutamic Acid (3KX376GY7L) ; Glutamine (0RH81L854J)
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2050438-X
    ISSN 1471-244X ; 1471-244X
    ISSN (online) 1471-244X
    ISSN 1471-244X
    DOI 10.1186/s12888-024-05646-x
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  4. Book ; Online ; Thesis: Software-basierte, automatische Berechnung des ASPECT Scores bei Patienten mit neu aufgetretenem großem Verschluss der vorderen Zirkulation: Klinische Umsetzbarkeit und Zuverlässigkeit

    Fischer, Johanna Maria [Verfasser] / Zimmer, Claus [Akademischer Betreuer] / Zimmer, Claus [Gutachter] / Stollfuss, Jens [Gutachter]

    2023  

    Author's details Johanna Maria Fischer ; Gutachter: Claus Zimmer, Jens Stollfuss ; Betreuer: Claus Zimmer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der TU München
    Publishing place München
    Document type Book ; Online ; Thesis
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  5. Book ; Online ; Thesis: Postinterventionelle Analyse von Rupturprädiktoren und Risikofaktoren hinsichtlich Rezidiventwicklung zerebraler Aneurysmen nach endovasculärer Coilversorgung

    Sukopp, Maximilian Michael [Verfasser] / Zimmer, Claus [Akademischer Betreuer] / Zimmer, Claus [Gutachter] / Wostrack, Maria [Gutachter]

    2023  

    Author's details Maximilian Michael Sukopp ; Gutachter: Claus Zimmer, Maria Wostrack ; Betreuer: Claus Zimmer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der TU München
    Publishing place München
    Document type Book ; Online ; Thesis
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  6. Book ; Online ; Thesis: Determinanten des klinischen Outcomes nach mechanischer Thrombektomie bei Verschlüssen der A. cerebri media

    Kaesmacher, Mirjam [Verfasser] / Zimmer, Claus [Akademischer Betreuer] / Zimmer, Claus [Gutachter] / Hohlweg-Majert, Bettina [Gutachter]

    2023  

    Author's details Mirjam Kaesmacher ; Gutachter: Claus Zimmer, Bettina Hohlweg-Majert ; Betreuer: Claus Zimmer
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der TU München
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Article ; Online: Future Neuroradiology.

    Zimmer, Claus / Trenkler, Johannes

    Clinical neuroradiology

    2019  Volume 29, Issue 2, Page(s) 187–188

    MeSH term(s) Humans ; Neuroradiography/trends
    Language English
    Publishing date 2019-03-30
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2234662-4
    ISSN 1869-1447 ; 0939-7116 ; 1869-1439
    ISSN (online) 1869-1447
    ISSN 0939-7116 ; 1869-1439
    DOI 10.1007/s00062-019-00796-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3413: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Impact of ischemic stroke topography on early clinical outcome of basilar artery occlusion: a retrospective study.

    Hernandez Petzsche, Moritz R / Maegerlein, Christian / Wunderlich, Silke / Ikenberg, Benno / Zimmer, Claus / Kirschke, Jan S / Boeckh-Behrens, Tobias / Berndt, Maria

    European radiology

    2024  

    Abstract: Objectives: Basilar artery occlusion (BAO) may be etiologically attributed to embolism or in situ thrombosis due to basilar stenosis (BS). Patients with BAO due to BS (BAOS) are known to have worse outcomes than patients with embolic occlusions (BAOE). ... ...

    Abstract Objectives: Basilar artery occlusion (BAO) may be etiologically attributed to embolism or in situ thrombosis due to basilar stenosis (BS). Patients with BAO due to BS (BAOS) are known to have worse outcomes than patients with embolic occlusions (BAOE). BAOS occurs more proximally in the basilar artery (BA) than BAOE. We hypothesize that differing brain stem infarct patterns contribute to outcome differences between these stroke etiologies.
    Methods: This retrospective study includes 199 consecutive patients with BAO who received endovascular treatment at a single center. Final infarction in brain parenchyma dependent on the posterior circulation was graded semiquantitatively on magnetic resonance imaging (MRI). Associations to underlying stenosis and angiographic and clinical outcome variables were tested. The primary endpoint was early good clinical outcome (EGCO, mRS score ≤ 3 at discharge).
    Results: Infarct extension of the medulla oblongata (OR = 0.25; 95% CI = 0.07-0.86; p = 0.03), the inferior pons (OR = 0.328; 95% CI = 0.17-0.63; p = 0.001), the superior pons (OR = 0.57; 95% CI = 0.33-0.99; p = 0.046), and the occipital lobes (OR = 0.46; 95% CI = 0.26-0.80; p = 0.006) negatively predicted EGCO. Infarct extension for other posterior-circulation-dependent brain regions was not independently associated with unfavorable early outcomes. Patients with BAOS had more proximal occlusions and greater infarct volumes in the inferior brain stem. Successful reperfusion (mTICI 2b-3) occurred more often in patients with BAOE than in BAOS (BAOE: 131 (96.3%); BAOS: 47 (83.9%), p = 0.005).
    Conclusion: Unfavorable early outcomes in patients with BAOS may be explained by a higher likelihood of inferior brain stem infarcts and lower rates of reperfusion success.
    Clinical relevance statement: Basilar artery occlusion due to underlying stenosis is associated with a poorer prognosis than that caused by embolism; these results suggest that aggressive endovascular therapy, usually involving the placement of a permanent stent, may be warranted in these patients.
    Key points: Inferior brain stem and occipital infarcts are prognostically unfavorable in basilar artery occlusion. Basilar artery occlusion due to stenosis occurs more proximally and is associated with worse outcomes. Differentiating etiologies of basilar artery occlusion may influence how aggressively treated the occlusion is.
    Language English
    Publishing date 2024-04-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-024-10755-y
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    Zs.A 3300: Show issues Location:
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  9. Article ; Online: Erratum to: Less is More: Removing a Modality of an Expected Olfactory-Visual Stimulation Enhances Brain Activation.

    Schicker, Doris / Blankenagel, Sonja / Zimmer, Claus / Hauner, Hans / Freiherr, Jessica

    Human brain mapping

    2022  Volume 43, Issue 13, Page(s) 4219

    Language English
    Publishing date 2022-07-22
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26023
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    Zs.A 4028: Show issues Location:
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  10. Article ; Online: Less is more: Removing a modality of an expected olfactory-visual stimulation enhances brain activation.

    Schicker, Doris / Blankenagel, Sonja / Zimmer, Claus / Hauner, Hans / Freiherr, Jessica

    Human brain mapping

    2022  Volume 43, Issue 8, Page(s) 2567–2581

    Abstract: In recent years, multisensory integration of visual and olfactory stimuli has extensively been explored resulting in the identification of responsible brain areas. As the experimental designs of previous research often include alternating presentations ... ...

    Abstract In recent years, multisensory integration of visual and olfactory stimuli has extensively been explored resulting in the identification of responsible brain areas. As the experimental designs of previous research often include alternating presentations of unimodal and bimodal stimuli, the conditions cannot be regarded as completely independent. This could lead to effects of an expected but surprisingly missing sensory modality. In our experiment, we used a common functional magnetic resonance imaging (fMRI) study design with alternating strong unimodal and bimodal olfactory-visual food stimuli, in addition to a slight overhang of the bimodal stimuli in an effort to examine the effects of removing a visual or olfactory congruent stimulus for older people (41-83 years). Our results suggest that the processing of olfactory and visual stimuli stays intact over a wide age-range and that the utilization of strong stimuli does not lead to superadditive multisensory integration in accordance with the principle of inverse effectiveness. However, our results demonstrate that the removal of a stimulus modality leads to an activation of additional brain areas. For example, when the visual stimulus modality is missing, the right posterior superior temporal gyrus shows higher activation, whereas the removal of the olfactory stimulus modality leads to higher activation in the amygdala/hippocampus and the postcentral gyrus. These brain areas are related to attention, memory, and the search of the missing stimulus. Consequently, careful attention must be paid to the design of a valid, multimodal sensory experiment while also controlling for cognitive expectancy effects that might confound multimodal results.
    MeSH term(s) Acoustic Stimulation ; Aged ; Auditory Perception/physiology ; Brain/diagnostic imaging ; Brain Mapping ; Humans ; Magnetic Resonance Imaging ; Photic Stimulation ; Smell ; Visual Perception/physiology
    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.25806
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