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  1. Book ; Thesis: Bedeutung seriell erhobener PET-Parameter für das Therapieoutcome von Patienten mit NSCLC und kurativer Radiochemotherapie unter Einschluss des mitbestrahlten Normalgewebes

    Mersch, Shenja / Zöphel, Klaus / Zips, Daniel

    2021  

    Institution Klinik und Poliklinik für Nuklearmedizin
    Author's details von Shenja Mersch, geb. Raulfs aus Hannover ; Klinik und Poliklinik für Nuklearmedizin [Dresden]
    Language German
    Size IV, 78 Blätter, Illustrationen, Diagramme
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, Medizinische Fakultät, 2021
    HBZ-ID HT021364475
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 E 505 order for loan Magazin

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  2. Article ; Online: Magnetic Resonance Imaging Guided Radiation Therapy: Overview.

    Low, Daniel / Zips, Daniel

    Seminars in radiation oncology

    2023  Volume 34, Issue 1, Page(s) 1–3

    MeSH term(s) Humans ; Magnetic Resonance Imaging/methods ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy, Image-Guided/methods
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 1146999-7
    ISSN 1532-9461 ; 1053-4296
    ISSN (online) 1532-9461
    ISSN 1053-4296
    DOI 10.1016/j.semradonc.2023.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3654: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  3. Book: Advances in radiation therapy

    Guckenberger, Matthias / Combs, Stephanie / Zips, Daniel

    (Progress in Tumor Research ; Vol. 44)

    2018  

    Series title Progress in Tumor Research ; Vol. 44
    Progress in tumor research
    Collection Progress in tumor research
    Keywords Neoplasms / radiotherapy ; Radiotherapy ; Elementary Particles / therapeutic use ; Radiotherapy Planning, Computer-Assisted ; Oncology ; Radiology ; Krebs ; Strahlentherapie
    Subject Bestrahlung ; Radiotherapie ; Strahlenbehandlung ; Radioonkologie ; Carcinom ; Malignom ; Maligner Tumor ; Neoplasma ; Karzinom ; Bösartiger Tumor ; Krebserkrankung
    Subject code 610
    Language English
    Size X, 133 Seiten, Illustrationen
    Edition 1. Auflage
    Publisher Karger
    Publishing place Basel
    Publishing country Switzerland ; Germany
    Document type Book
    HBZ-ID HT019699665
    ISBN 978-3-318-06361-5 ; 3-318-06361-4 ; 9783318063622 ; 3318063622
    Database Catalogue ZB MED Medicine, Health

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    Uh III Zs 200 -44- verfügbar in Königswinter Königswinter

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  4. Book ; Conference proceedings: Proceedings des 28. Symposiums Experimentelle Strahlentherapie und Klinische Strahlenbiologie "Präklinische und translationale Strahlentherapie"

    Cordes, Nils / Krause, Mechthild / Petersen, Cordula / Rodemann, Hans Peter / Rothkamm, Kai / Zips, Daniel / Baumann, Michael

    Dresden, 14.-16. März 2019

    (Experimentelle Strahlentherapie und klinische Strahlenbiologie ; 28)

    2019  

    Title variant Präklinische und translationale Strahlentherapie und personalisierte Medizin: -omics
    Event/congress Symposium Experimentelle Strahlentherapie und Klinische Strahlenbiologie "Präklinische und translationale Strahlentherapie (28., 2019, Dresden)
    Author's details Herausgegeben von Michael Baumann, Nils Cordes, Mechthild Krause, Cordula Petersen, H. Peter Rodemann, Kai Rothkamm, Daniel Zips
    Series title Experimentelle Strahlentherapie und klinische Strahlenbiologie ; 28
    Collection
    Language German ; English
    Size 95 Seiten, Illustrationen
    Publisher Selbstverlag
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Conference proceedings
    HBZ-ID HT020023730
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 A 417 available for loan (reading room) Lesesaal EG

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  5. Article: Positionierungs- und Trackingtechnologie: Optimierte Strahlentherapie bei Brustkrebs

    Zips, Daniel / Senger, Carolin

    kma - Klinik Management aktuell

    2023  Volume 28, Issue 02/03, Page(s) 46–48

    Abstract: Ein neuer herzschonender Deep-Inspiration-Breath-Hold-Workflow (DIBH) verbessert bei Patientinnen mit linksseitigem Mammakarzinom die Behandlungsqualität, sorgt für mehr Lebensqualität während der Therapie und kürzere Liegezeiten sowie für ein ... ...

    Abstract Ein neuer herzschonender Deep-Inspiration-Breath-Hold-Workflow (DIBH) verbessert bei Patientinnen mit linksseitigem Mammakarzinom die Behandlungsqualität, sorgt für mehr Lebensqualität während der Therapie und kürzere Liegezeiten sowie für ein erleichtertes Handling im Routinebetrieb der Klinik.
    Language German
    Publishing date 2023-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2106067-8
    ISSN 2197-621X ; 1439-3514
    ISSN (online) 2197-621X
    ISSN 1439-3514
    DOI 10.1055/s-0043-1768307
    Database Thieme publisher's database

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  6. Book ; Thesis: Untersuchung zum Purinkatabolismus bei Patienten mit Merkmalen des metabolischen Syndroms durch Bestimmung der enzymatischen Aktivität der Adenosindesaminase und Purinnukleosidphosphorylase in Erythrozyten

    Zips, Daniel

    1999  

    Author's details vorgelegt von Daniel Zips
    Language German
    Size 83, [18] Bl., Ill., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dresden, Techn. Univ., Diss., 2000
    HBZ-ID HT012966012
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 E 923 order for loan Magazin

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  7. Article ; Online: Plasma sICAM-1 correlates with tumor volume before primary radiochemotherapy of head and neck squamous cell carcinoma patients

    Clasen Kerstin / Welz Stefan / Faltin Heidrun / Zips Daniel / Eckert Franziska

    Radiology and Oncology, Vol 56, Iss 4, Pp 501-

    2022  Volume 507

    Abstract: Biomarkers are of major interest to optimize diagnosis, prognosis and to guide treatment in head and neck cancer patients. Especially blood-based biomarkers appear promising as they can be easily collected and repeatedly analyzed during the course of ... ...

    Abstract Biomarkers are of major interest to optimize diagnosis, prognosis and to guide treatment in head and neck cancer patients. Especially blood-based biomarkers appear promising as they can be easily collected and repeatedly analyzed during the course of radiochemotherapy.
    Keywords head and neck cancer ; biomarker ; radiotherapy ; tumor volume ; gross tumor volume ; sicam-1 ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Full daily re-optimization improves plan quality during online adaptive radiotherapy.

    Tengler, Benjamin / Künzel, Luise A / Hagmüller, Markus / Mönnich, David / Boeke, Simon / Wegener, Daniel / Gani, Cihan / Zips, Daniel / Thorwarth, Daniela

    Physics and imaging in radiation oncology

    2024  Volume 29, Page(s) 100534

    Abstract: Background and purpose: Daily online treatment plan adaptation requires a fast workflow and planning process. Current online planning consists of adaptation of a predefined reference plan, which might be suboptimal in cases of large anatomic changes. ... ...

    Abstract Background and purpose: Daily online treatment plan adaptation requires a fast workflow and planning process. Current online planning consists of adaptation of a predefined reference plan, which might be suboptimal in cases of large anatomic changes. The aim of this study was to investigate plan quality differences between the current online re-planning approach and a complete re-optimization.
    Material and methods: Magnetic resonance linear accelerator reference plans for ten prostate cancer patients were automatically generated using particle swarm optimization (PSO). Adapted plans were created for each fraction using (1) the current re-planning approach and (2) full PSO re-optimization and evaluated overall compliance with institutional dose-volume criteria compared to (3) clinically delivered fractions. Relative volume differences between reference and daily anatomy were assessed for planning target volumes (PTV60, PTV57.6), rectum and bladder and correlated with dose-volume results.
    Results: The PSO approach showed significantly higher adherence to dose-volume criteria than the reference approach and clinical fractions (p < 0.001). In 74 % of PSO plans at most one criterion failed compared to 56 % in the reference approach and 41 % in clinical plans. A fair correlation between PTV60 D98% and relative bladder volume change was observed for the reference approach. Bladder volume reductions larger than 50 % compared to the reference plan recurrently decreased PTV60 D98% below 56 Gy.
    Conclusion: Complete re-optimization maintained target coverage and organs at risk sparing even after large anatomic variations. Re-planning based on daily magnetic resonance imaging was sufficient for small variations, while large variations led to decreasing target coverage and organ-at-risk sparing.
    Language English
    Publishing date 2024-01-10
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2405-6316
    ISSN (online) 2405-6316
    DOI 10.1016/j.phro.2024.100534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Plasma sICAM-1 correlates with tumor volume before primary radiochemotherapy of head and neck squamous cell carcinoma patients.

    Clasen, Kerstin / Welz, Stefan / Faltin, Heidrun / Zips, Daniel / Eckert, Franziska

    Radiology and oncology

    2022  Volume 56, Issue 4, Page(s) 501–507

    Abstract: Background: Biomarkers are of major interest to optimize diagnosis, prognosis and to guide treatment in head and neck cancer patients. Especially blood-based biomarkers appear promising as they can be easily collected and repeatedly analyzed during the ... ...

    Abstract Background: Biomarkers are of major interest to optimize diagnosis, prognosis and to guide treatment in head and neck cancer patients. Especially blood-based biomarkers appear promising as they can be easily collected and repeatedly analyzed during the course of radiochemotherapy.
    Patients and methods: At first, for a broad overview, multiple immune markers were evaluated in six plasma samples of three head and neck squamous cell carcinoma (HNSCC) patients at the beginning and the end of radio-chemotherapy. In this pre-selection, the soluble Intercellular Adhesion Molecule 1 (sICAM-1) appeared most promising. Thus, this marker was measured in multiple samples (n = 86) during treatment and follow-up in a cohort of eleven patients and correlated with tumor features and clinical data.
    Results: We found a strong correlation between the initial levels of sICAM-1 in the plasma and the gross tumor volumes of the primary tumor and the involved lymph nodes. However, during the course of treatment no systematic dynamics could be identified. Toxicity or infections did not seem to influence sICAM-1 concentrations.
    Conclusions: sICAM-1 appears to reflect the pre-treatment total tumor burden (primary tumor and involved lymph nodes) in head and neck tumor patients. However, it does not seem to be a dynamic marker reflecting response during radiochemotherapy. Thus, if our findings are confirmed in future, sICAM-1 could be used as a staging marker: if high sICAM-1 levels but low tumor burden are found it might be reasonable to intensify staging investigations to rule out further, yet undetected, tumor sites.
    MeSH term(s) Humans ; Squamous Cell Carcinoma of Head and Neck/therapy ; Tumor Burden ; Intercellular Adhesion Molecule-1 ; Chemoradiotherapy ; Head and Neck Neoplasms/therapy
    Chemical Substances Intercellular Adhesion Molecule-1 (126547-89-5)
    Language English
    Publishing date 2022-12-13
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 1128829-2
    ISSN 1581-3207 ; 0485-893X ; 1318-2099
    ISSN (online) 1581-3207
    ISSN 0485-893X ; 1318-2099
    DOI 10.2478/raon-2022-0043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2674: Show issues Location:
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  10. Article ; Online: PSMA PET-based stereotactic body radiotherapy for locally recurrent prostate cancer after definitive first-line therapy.

    Gruen, Arne / Tegel, Katharina / Kluge, Anne / Budach, Volker / Zips, Daniel / Boehmer, Dirk

    The Prostate

    2023  Volume 83, Issue 13, Page(s) 1298–1305

    Abstract: Background: Advances in prostate-specific membrane antigen (PSMA) PET-computed tomography (CT) and magnetic resonance imaging (MRI) allow the detection and localization of exclusively local prostate-cancer-recurrences after definitive first-line therapy. ...

    Abstract Background: Advances in prostate-specific membrane antigen (PSMA) PET-computed tomography (CT) and magnetic resonance imaging (MRI) allow the detection and localization of exclusively local prostate-cancer-recurrences after definitive first-line therapy. PSMA-based early detection of circumscribed local recurrences followed by hypofractionated high-precision stereotactic body radiotherapy (SBRT) might yield long-term disease control at moderate rates of adverse effects.
    Methods: Retrospective analysis of 35 patients treated for locally recurrent prostate cancer between November 2012 and December 2021 with PSMA PET- and MRI-based robotic SBRT.
    Results: Thirty-five patients treated with local prostate cancer recurrence post surgery, post surgery, and adjuvant/salvage radiotherapy (RT) and after definitive RT. All but one patients had fractionated SBRT in 3-5 fractions. Median progression-free survival (PFS) was 52.2 months for all patients and 52.2 months in the radical prostatectomy (RPE) group, 31.2 months in the RPE + RT group and not reached in the RT group. The most common event was increased urinary frequency grade 1-2. 54.3% of all patients had no acute and 79.4% no late toxicity during follow-up.
    Discussion: Our PFS of 52.2 months (RPE), 31.2 months (RPE + RT) and not reached (RT) compares favorably with published data. This method constitutes a valid alternative to morbidity-prone invasive approaches or palliative systemic therapy.
    MeSH term(s) Male ; Humans ; Radiosurgery/methods ; Prostate/pathology ; Retrospective Studies ; Positron Emission Tomography Computed Tomography/methods ; Neoplasm Recurrence, Local/diagnostic imaging ; Neoplasm Recurrence, Local/radiotherapy ; Neoplasm Recurrence, Local/pathology ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/radiotherapy ; Prostatic Neoplasms/pathology ; Prostate-Specific Antigen ; Prostatectomy ; Gallium Radioisotopes
    Chemical Substances Prostate-Specific Antigen (EC 3.4.21.77) ; Gallium Radioisotopes
    Language English
    Publishing date 2023-07-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604707-5
    ISSN 1097-0045 ; 0270-4137
    ISSN (online) 1097-0045
    ISSN 0270-4137
    DOI 10.1002/pros.24592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1608: Show issues Location:
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