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  1. Article ; Online: Economizing Socialist Aid: China's Failed Surgical Plant in Algeria, 1973-80.

    Zou, Dongxin

    Technology and culture

    2022  Volume 63, Issue 3, Page(s) 718–748

    Abstract: China is currently a source of technology for the developing world, yet little is known about its transfer of modern technologies before the 1980s liberalization. This article excavates a failed surgical turn-key project that China planned in the mid- ... ...

    Abstract China is currently a source of technology for the developing world, yet little is known about its transfer of modern technologies before the 1980s liberalization. This article excavates a failed surgical turn-key project that China planned in the mid-1970s at Médéa in state socialist Algeria. The case of South-South collaboration analyzes how three principles-simplification, economization, and improvement of labor efficiency-dominated the negotiations and design process. The Chinese aspired to transfer technology suiting Algeria, but were restricted by capital input, technological capacity, and the pragmatism of convenience, as well as a distorted vision of Algerians' needs. This article puts Chinese industrial aid into perspective within the history of appropriate technology, examining the asymmetries in perceptions, interests, and priorities that sank this early attempt at South-South cooperation. By uncovering the often-neglected perspective of Chinese aid technocrats, it also breaks the stereotype of Maoist China ignoring cost effectiveness in its foreign aid.
    MeSH term(s) Algeria ; China ; General Surgery ; Humans ; International Cooperation ; Socialism
    Language English
    Publishing date 2022-07-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2021131-4
    ISSN 1097-3729 ; 0040-165X
    ISSN (online) 1097-3729
    ISSN 0040-165X
    DOI 10.1353/tech.2022.0107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Construction and validation of a colon cancer prognostic model based on tumor mutation burden-related genes.

    Zou, Daoyang / Xu, Tianwen

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2867

    Abstract: Currently, immunotherapy has entered the clinical diagnosis and treatment guidelines for colon cancer, but existing immunotherapy markers cannot predict the effectiveness of immunotherapy well. This study utilized the TCGA-COAD queue to perform ... ...

    Abstract Currently, immunotherapy has entered the clinical diagnosis and treatment guidelines for colon cancer, but existing immunotherapy markers cannot predict the effectiveness of immunotherapy well. This study utilized the TCGA-COAD queue to perform differential gene analysis on high and low-mutation burden samples, and screen differentially expressed genes (DEGs). To explore new molecular markers or predictive models of immunotherapy by using DEGs for NMF classification and prognostic model construction. Through systematic bioinformatics analysis, the TCGA-COAD cohort was successfully divided into high mutation burden subtypes and low mutation burden subtypes by NMF typing using DEGs. The proportion of MSI-H between high mutation burden subtypes was significantly higher than that of low mutation burden subtypes, but there was no significant difference in immunotherapy efficacy between the two subtypes. Drug sensitivity analysis showed significant differences in drug sensitivity between the two subtypes. Subsequently, we constructed a prognostic model using DEGs, which can effectively predict patient survival and immunotherapy outcomes. The prognosis and immunotherapy outcomes of the low-risk group were significantly better than those of the high-risk group. The external dataset validation of the constructed prognostic model using the GSE39582 dataset from the GEO database yielded consistent results. At the same time, we also analyzed the TMB and MSI situation between the high and low-risk groups, and the results showed that there was no significant difference in TMB between the high and low-risk groups, but the proportion of MSI-H in the high-risk group was significantly higher than that in the low-risk group. Finally, we conclude that TMB is not a suitable molecular marker for predicting the efficacy of immunotherapy in colon cancer. The newly constructed prognostic model can effectively differentiate the prognosis of colon cancer patients and predict their immunotherapy efficacy.
    MeSH term(s) Humans ; Prognosis ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/genetics ; Colonic Neoplasms/therapy ; Immunotherapy ; Computational Biology ; Microsatellite Instability ; Mutation
    Language English
    Publishing date 2024-02-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53257-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: "Please don't lyse me": Programmed cell death ligand-1 expression on neonatal islet cells promotes xenotransplant acceptance.

    Li, Shuang / Zou, Dawei

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2024  

    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Letter
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1016/j.ajt.2024.02.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5542: Show issues Location:
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  4. Article ; Online: Tirofiban-induced thrombocytopenia.

    Wang, Jun / Zou, Dongna

    Annals of medicine

    2023  Volume 55, Issue 1, Page(s) 2233425

    Abstract: Tirofiban is a small non-peptide ligand-mimetic Glycoprotein (GP) IIb/IIIa inhibitor which can reversibly bind to the arginine-glycine-aspartic acid (RGD) recognition site of GP IIb/IIIa to prevent platelet aggregation. It reduces the incidence of ... ...

    Abstract Tirofiban is a small non-peptide ligand-mimetic Glycoprotein (GP) IIb/IIIa inhibitor which can reversibly bind to the arginine-glycine-aspartic acid (RGD) recognition site of GP IIb/IIIa to prevent platelet aggregation. It reduces the incidence of thrombotic cardiovascular events in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Although generally considered safe, tirofiban has been reported to be associated with thrombocytopenia in several case reports and clinical trials. The pathogenesis for this adverse reaction is not entirely understood, is thought to be due to immune-mediated reaction. This side effect caused by tirofiban is especially concerning given how frequently it is used in the practice of contemporary cardiovascular care. The present review provides an overview of the pathophysiology, clinical presentation, management, and risk factors associated with tirofiban-induced thrombocytopenia.
    MeSH term(s) Humans ; Tirofiban/adverse effects ; Platelet Aggregation Inhibitors/adverse effects ; Tyrosine/adverse effects ; Thrombocytopenia/chemically induced ; Thrombocytopenia/drug therapy ; Platelet Glycoprotein GPIIb-IIIa Complex/adverse effects ; Acute Coronary Syndrome/drug therapy
    Chemical Substances Tirofiban (GGX234SI5H) ; Platelet Aggregation Inhibitors ; Tyrosine (42HK56048U) ; Platelet Glycoprotein GPIIb-IIIa Complex
    Language English
    Publishing date 2023-07-13
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1004226-x
    ISSN 1365-2060 ; 1651-2219 ; 0785-3890 ; 1743-1387
    ISSN (online) 1365-2060 ; 1651-2219
    ISSN 0785-3890 ; 1743-1387
    DOI 10.1080/07853890.2023.2233425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Association of CT phenotype with pulmonary function in patients with chronic obstructive pulmonary disease and influencing factors of prognosis.

    Zou, Dianjun / Zhu, Xiaolong

    American journal of translational research

    2023  Volume 15, Issue 3, Page(s) 2164–2174

    Abstract: Objective: To determine the correlation between computed tomography (CT) phenotype and pulmonary function in patients with chronic obstructive pulmonary disease (COPD) and to analyze the influencing factors of prognosis.: Methods: In this ... ...

    Abstract Objective: To determine the correlation between computed tomography (CT) phenotype and pulmonary function in patients with chronic obstructive pulmonary disease (COPD) and to analyze the influencing factors of prognosis.
    Methods: In this retrospective study, a total of 174 COPD patients admitted to the First Affiliated Hospital of Hebei North University from May 2017 to October 2020 were enrolled and assigned to the M-type group (n = 48), E-type group (n = 56) or A-type group (n = 70) according to their CT features. The CT features and pulmonary function indexes of all the patients and their correlation were analyzed, and the acute exacerbation in one-year follow-up of the patients was recorded. Logistic regression was carried out to analyze the influencing factors for the prognosis of COPD.
    Results: The A-type group showed significantly better pulmonary function than the E-type group and M-type group (P < 0.05), and the degree of emphysema was negatively correlated with pulmonary function. The A-type group showed a significantly lower one-year acute exacerbation rate than the other two groups (P < 0.05). A relatively longer course of disease, a relatively lower forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC) ratio and CT phenotype were correlated with the unfavorable prognosis of patients.
    Conclusion: According to determination of the pulmonary function of patients with COPD through CT, the degree of emphysema worsens with the progression of the disease. A relatively longer course of disease, a relatively lower FEV1/FVC ratio and CT phenotype are independent risk factors for unfavorable prognosis of COPD patients.
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
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  6. Article ; Online: Enhanced tunneling electroresistance through interfacial charge-modulated barrier in

    He, Shiying / Zou, Daifeng

    Journal of physics. Condensed matter : an Institute of Physics journal

    2023  Volume 36, Issue 11

    Abstract: The manipulation of tunneling resistance is critical for ferroelectric tunnel junction (FTJ) devices. In this work, we propose a mechanism to manipulate tunneling resistance through interfacial charge-modulated barrier in two-dimensional (2D) ...

    Abstract The manipulation of tunneling resistance is critical for ferroelectric tunnel junction (FTJ) devices. In this work, we propose a mechanism to manipulate tunneling resistance through interfacial charge-modulated barrier in two-dimensional (2D)
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/ad1301
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  7. Article ; Online: The impact of the COVID-19 pandemic on the mental health of new mothers in China: A qualitative study of mothers with infants aged 0-1 year old.

    Zou, Dandan / Chen, Chen

    Frontiers in public health

    2023  Volume 11, Page(s) 1138349

    Abstract: Background: China has implemented a strict epidemic control policy (ECP) for 3 years during the COVID-19 pandemic. New mothers are under great psychological pressure to protect themselves against the virus, following the ECP, as well as taking on the ... ...

    Abstract Background: China has implemented a strict epidemic control policy (ECP) for 3 years during the COVID-19 pandemic. New mothers are under great psychological pressure to protect themselves against the virus, following the ECP, as well as taking on the main responsibility of raising their children. However, the mental health of this group has been neglected by the public. This article aims to understand the mental health of new mothers during the COVID-19 pandemic.
    Method: Qualitative research methods were adopted in this study. From 1 October to 1 November 2022, we conducted in-depth interviews with 36 new mothers in Guiyang, Guizhou, China, and used thematic analysis to examine their emotional status, as well as the origins of their negative and positive emotions.
    Results: (1) New mothers are chronically depressed, feeling anxious, and upset. (2) Negative emotions are caused either by the virus or by the ECP. (3) New mothers are mainly anxious about their children's physical health, feeding options, childcare, and family income. (4) Positive emotions are reflected by tight parent-child bonds, a better understanding of childcare, and an increased ability to perceive risks.
    Conclusion: The anxiety of new mothers has revealed the shortcomings of the Chinese health system in the emergency management of the mother and child. At the same time, the outbreak is an opportunity to improve the response management capacity of the health system in order to prevent the recurrence of similar problems for mothers and infants.
    MeSH term(s) Female ; Humans ; Infant ; Infant, Newborn ; Mothers/psychology ; COVID-19/epidemiology ; Mental Health ; Pandemics ; China/epidemiology ; Qualitative Research
    Language English
    Publishing date 2023-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1138349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Progresses and hot spots of type 1 autoimmune pancreatitis in the past decade].

    Zhou, C H / Zou, D W

    Zhonghua nei ke za zhi

    2023  Volume 63, Issue 1, Page(s) 13–16

    MeSH term(s) Humans ; Autoimmune Pancreatitis
    Language Chinese
    Publishing date 2023-12-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    DOI 10.3760/cma.j.cn112138-20231015-00215
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  9. Article ; Online: A bibliometric analysis on research hot-spot and publication trends in immunotherapy for cervical cancer after surgery.

    Zou, Dan / Liang, Ailin

    Asian journal of surgery

    2023  Volume 46, Issue 8, Page(s) 3178–3179

    MeSH term(s) Humans ; Female ; Uterine Cervical Neoplasms/surgery ; Bibliometrics ; Immunotherapy
    Language English
    Publishing date 2023-03-09
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.02.109
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  10. Article ; Online: Harnessing mixed chimerism and programmed cell death protein 1/programmed death ligand 1 signaling for transplant tolerance.

    Li, Shuang / Zou, Dawei

    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

    2023  Volume 24, Issue 1, Page(s) 147–148

    MeSH term(s) B7-H1 Antigen/metabolism ; Programmed Cell Death 1 Receptor/metabolism ; Chimerism ; Transplantation Tolerance
    Chemical Substances B7-H1 Antigen ; Programmed Cell Death 1 Receptor
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Letter
    ZDB-ID 2060594-8
    ISSN 1600-6143 ; 1600-6135
    ISSN (online) 1600-6143
    ISSN 1600-6135
    DOI 10.1016/j.ajt.2023.09.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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