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Article: Chronic Obstructive Pulmonary Disease Risk and Smoking Cessation Changes Induced by

Zhao, L / Zou, L-Y / Cheng, B-F / Yu, X-J / Zou, J-H / Han, W

Balkan journal of medical genetics : BJMG

2019 Volume 22, Issue 2, Page(s) 51–58

Abstract: Most studies in the field ... ...

Abstract	Most studies in the field of
Language	English
Publishing date	2019-12-21
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2039837-2
ISSN	2199-5761 ; 1311-0160
ISSN (online)	2199-5761
ISSN	1311-0160
DOI	10.2478/bjmg-2019-0018
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Article ; Online: High expression of long noncoding RNA Sox2ot is associated with the aggressive progression and poor outcome of gastric cancer.

Zou, J-H / Li, C-Y / Bao, J / Zheng, G-Q

European review for medical and pharmacological sciences

2016 Volume 20, Issue 21, Page(s) 4482–4486

Abstract: Objective: The aim of our study was to investigate the expression of long non-coding RNA Sox2ot (Sox2ot) in gastric cancer (GC) patients and its association with clinicopathologic parameters and the prognosis.: Patients and methods: Quantitative real- ...

Abstract	Objective: The aim of our study was to investigate the expression of long non-coding RNA Sox2ot (Sox2ot) in gastric cancer (GC) patients and its association with clinicopathologic parameters and the prognosis. Patients and methods: Quantitative real-time polymerase chain reaction was performed to detect Sox2ot expression in 155 GC tissues and paired adjacent normal tissues. The relationships between Sox2ot expression and the clinicopathological features of GC patients were analyzed. Furthermore, overall survival (OS) and disease-free survival (DFS) were evaluated using the Kaplan-Meier method, and multivariate analysis was performed using the Cox proportional hazard analysis. Results: Sox2ot expression levels were decreased in cancerous tissues compared to their corresponding non-cancerous controls (p < 0.01). Sox2ot expression was associated with T stage, distant metastasis and differentiation (p = 0.009, 0.034 and 0.001, respectively). In addition, patients with high Sox2ot expression tended to have poorer OS and DFS (p < 0.001, respectively). Finally, multivariate analysis showed Sox2ot expression was an independent prognostic factor for GC patients. Conclusions: Our ﬁndings showed that overexpressed Sox2ot was correlated with aggressive tumor behavior. Sox2ot may serve as a novel prognostic factor and a potential target to improve the long-term outcome of GC.
MeSH term(s)	Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Kaplan-Meier Estimate ; Prognosis ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism ; Up-Regulation
Chemical Substances	Biomarkers, Tumor ; RNA, Long Noncoding ; long non-coding RNA Sox2ot, human
Language	English
Publishing date	2016-11
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
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Article ; Online: miR-194 inhibits gastric cancer cell proliferation and tumorigenesis by targeting KDM5B.

Bao, J / Zou, J-H / Li, C-Y / Zheng, G-Q

European review for medical and pharmacological sciences

2016 Volume 20, Issue 21, Page(s) 4487–4493

Abstract: Objective: MicroRNAs play critical roles in regulating gene expression and various cellular processes in human cancer malignant progression. The aim of the present study was to examine the expression pattern of miR-194 in gastric cancer (GC) and its ... ...

Abstract	Objective: MicroRNAs play critical roles in regulating gene expression and various cellular processes in human cancer malignant progression. The aim of the present study was to examine the expression pattern of miR-194 in gastric cancer (GC) and its biological role in tumor progression. Materials and methods: Using quantitative RT-PCR, we detected miR-194 expression in GC cell lines and primary tumor tissues. The proliferation, migration, and invasion assays were performed to investigate the effect of miR-194 on the GC cells. The target of miR-194 was predicted by TargetScan and confirmed by luciferase reporter assay. KDM5B expression was detected by Western blot. Results: miR-194 was significantly down-regulated in GC tissues and cell lines. Over-expression of miRNA-194 could inhibit GC cell proliferation, migration, and invasion in vitro. Also, miR-194 inhibited tumor growth and progression in vivo. Dual luciferase-based reporter assay indicated direct regulation of KDM5B by miR-194. Conclusions: Our findings suggested that miR-194 directly targeted KDM5B and thereby acted as a tumor promoter in GC progression.
MeSH term(s)	Carcinogenesis ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Humans ; Jumonji Domain-Containing Histone Demethylases/genetics ; MicroRNAs/genetics ; Neoplasm Invasiveness ; Nuclear Proteins/genetics ; Repressor Proteins/genetics ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism
Chemical Substances	MIRN194 microRNA, human ; MicroRNAs ; Nuclear Proteins ; Repressor Proteins ; Jumonji Domain-Containing Histone Demethylases (EC 1.14.11.-) ; KDM5B protein, human (EC 1.14.11.-)
Language	English
Publishing date	2016-11
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
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Article: [Analysis of screening strategy of group B streptococcus in the third trimester and its influence on pregnancy outcome].

Wu, L J / Wang, F L / Zou, J H / Yang, J / Huang, Y E / Ming, F / Chen, X R / Chen, R R / Zhu, Y F

Zhonghua fu chan ke za zhi

2019 Volume 54, Issue 3, Page(s) 154–159

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis/methods ; Child ; Female ; Humans ; Incidence ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/drug therapy ; Pregnancy Complications, Infectious/microbiology ; Pregnancy Outcome ; Pregnancy Trimester, Third ; Streptococcal Infections/diagnosis ; Streptococcal Infections/drug therapy ; Streptococcal Infections/epidemiology ; Streptococcal Infections/prevention & control ; Streptococcus agalactiae/isolation & purification
Chemical Substances	Anti-Bacterial Agents
Language	Chinese
Publishing date	2019-03-20
Publishing country	China
Document type	Journal Article
ZDB-ID	604570-4
ISSN	0529-567X
ISSN	0529-567X
DOI	10.3760/cma.j.issn.0529-567x.2019.03.003
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Zs.A 1619: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: Simultaneous and confirmative detection of multi-residues of β2-agonists and β-blockers in urine using LC-MS/MS/MS coupled with β-receptor molecular imprinted polymer SPE clean-up

Fan, S / Zou, J.H / Miao, H / Zhao, Y.F / Chen, H.J / Zhao, R / Wu, Y.N

Food additives & contaminants. 2013 Dec. 1, v. 30, no. 12

2013

Abstract: A liquid chromatography–linear ion-trap spectrometry (LC-MS ³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β ₂-agonists and ...

Abstract	A liquid chromatography–linear ion-trap spectrometry (LC-MS ³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β ₂-agonists and 21 β-blockers in urine samples. Urine samples were subjected to enzymatic hydrolysis by β-glucoronidase/arylsulphatase, and then extracted with perchloric acid. Sample clean-up was performed using β-receptor MIP SPE. A Supelco Ascentis ® express Rp-Amide column was used to separate the analytes, and MS ³ detection used an electrospray ionisation source in positive-ion mode. Recovery studies were carried out using blank urine samples fortified with the 46 analytes at the levels of 0.5, 1.0 and 2.0 μg l –¹. Recoveries were obtained ranging from 60.1% to 109.9% with relative standard deviations (RSDs, n = 7) from 0.5% to 19.4%. The limits of detection (LODs) and limits of quantitation (LOQs) of the 46 analytes in urine were 0.02–0.18 and 0.05–0.60 μg l –¹, respectively. As a result of the selective clean-up by MIP SPE and MS ³ detection of the target drugs, the sensitivity and accuracy of the present method was high enough for monitoring β ₂-agonist and β-blocker residues in urine samples. Satisfactory results were obtained in the process of the determination of positive urine samples.
Keywords	beta-adrenergic antagonists ; detection limit ; enzymatic hydrolysis ; ionization ; molecular imprinting ; monitoring ; perchloric acid ; polymers ; solid phase extraction ; spectroscopy ; urine
Language	English
Dates of publication	2013-1201
Size	p. 2093-2101.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	2462951-0
ISSN	1944-0057 ; 1944-0049
ISSN (online)	1944-0057
ISSN	1944-0049
DOI	10.1080/19440049.2013.840929
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Article: Acylated flavone C-glycosides from Trollius ledebouri

Zou, J.H / Yang, J.S / Zhou, L

Journal of natural products. 2004 Apr., v. 67, no. 4

2004

Language	English
Dates of publication	2004-04
Size	p. 664-667.
Document type	Article
ZDB-ID	304325-3
ISSN	1520-6025 ; 0163-3864
ISSN (online)	1520-6025
ISSN	0163-3864
Database	NAL-Catalogue (AGRICOLA)

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Zs.A 1144: Show issues

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Article ; Online: Simultaneous and confirmative detection of multi-residues of β₂-agonists and β-blockers in urine using LC-MS/MS/MS coupled with β-receptor molecular imprinted polymer SPE clean-up.

Fan, S / Zou, J H / Miao, H / Zhao, Y F / Chen, H J / Zhao, R / Wu, Y N

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment

2013 Volume 30, Issue 12, Page(s) 2093–2101

Abstract: A liquid chromatography-linear ion-trap spectrometry (LC-MS³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β₂-agonists and ... ...

Abstract	A liquid chromatography-linear ion-trap spectrometry (LC-MS³) method using β-receptor molecular-imprinted polymer (MIP) solid-phase extraction (SPE) as clean-up was developed to determine simultaneously and confirmatively residues of 25 β₂-agonists and 21 β-blockers in urine samples. Urine samples were subjected to enzymatic hydrolysis by β-glucoronidase/arylsulphatase, and then extracted with perchloric acid. Sample clean-up was performed using β-receptor MIP SPE. A Supelco Ascentis® express Rp-Amide column was used to separate the analytes, and MS³ detection used an electrospray ionisation source in positive-ion mode. Recovery studies were carried out using blank urine samples fortified with the 46 analytes at the levels of 0.5, 1.0 and 2.0 μg l⁻¹. Recoveries were obtained ranging from 60.1% to 109.9% with relative standard deviations (RSDs, n = 7) from 0.5% to 19.4%. The limits of detection (LODs) and limits of quantitation (LOQs) of the 46 analytes in urine were 0.02-0.18 and 0.05-0.60 μg l⁻¹, respectively. As a result of the selective clean-up by MIP SPE and MS³ detection of the target drugs, the sensitivity and accuracy of the present method was high enough for monitoring β₂-agonist and β-blocker residues in urine samples. Satisfactory results were obtained in the process of the determination of positive urine samples.
MeSH term(s)	Adrenergic beta-Agonists/metabolism ; Adrenergic beta-Agonists/urine ; Adrenergic beta-Antagonists/metabolism ; Adrenergic beta-Antagonists/urine ; Analytic Sample Preparation Methods/veterinary ; Animals ; Arylsulfatases/metabolism ; China ; Chromatography, High Pressure Liquid/veterinary ; Glucuronidase/metabolism ; Humans ; Hydrolysis ; Immobilized Proteins/agonists ; Immobilized Proteins/antagonists & inhibitors ; Immobilized Proteins/metabolism ; Limit of Detection ; Molecular Imprinting ; Receptors, Adrenergic, beta/chemistry ; Receptors, Adrenergic, beta/metabolism ; Reproducibility of Results ; Solid Phase Extraction/veterinary ; Spectrometry, Mass, Electrospray Ionization/veterinary ; Substance Abuse Detection/methods ; Substance Abuse Detection/veterinary ; Sus scrofa ; Tandem Mass Spectrometry/veterinary
Chemical Substances	Adrenergic beta-Agonists ; Adrenergic beta-Antagonists ; Immobilized Proteins ; Receptors, Adrenergic, beta ; Arylsulfatases (EC 3.1.6.1) ; Glucuronidase (EC 3.2.1.31)
Language	English
Publishing date	2013
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2462951-0
ISSN	1944-0057 ; 1944-0049
ISSN (online)	1944-0057
ISSN	1944-0049
DOI	10.1080/19440049.2013.840929
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Article ; Online: High expression of CXCR7 combined with Alpha fetoprotein in hepatocellular carcinoma correlates with extra-hepatic metastasis to lung after hepatectomy.

Xue, T C / Han, D / Chen, R X / Zou, J H / Wang, Y / Tang, Z Y / Ye, S L

Asian Pacific journal of cancer prevention : APJCP

2011 Volume 12, Issue 3, Page(s) 657–663

Abstract: The lung is the most frequent metastatic site of hepatocellular carcinoma (HCC), negatively impacting on survival rates. In this study, we evaluated the prognostic role of the chemokine receptor CXCR7 in lung metastasis of HCC after hepatectomy, using ... ...

Abstract	The lung is the most frequent metastatic site of hepatocellular carcinoma (HCC), negatively impacting on survival rates. In this study, we evaluated the prognostic role of the chemokine receptor CXCR7 in lung metastasis of HCC after hepatectomy, using immunohistochemical detection on tissue microarrays of HCCs, with and without lung metastasis. Using three categories based on staining characteristics, patients with high CXCR7 expression demonstrated a shorter time to development of lung metastasis compared with patients with low CXCR7 expression (log-rank test) with no effet on overall survival. Analysis of tissue adjacent to tumor showed patients with microvascular invasion to have higher CXCR7. Stratification based on alpha fetoprotein level >20 ng/ml also showed high expression of CXCR7 to be a strong independent prognostic factor. These findings suggest that high expression of CXCR7 in HCCs with elevated alpha fetoprotein levels correlates with metastasis to lung and poor survival after hepatectomy, indicating potential use as a prognostic factor.
MeSH term(s)	Adolescent ; Adult ; Aged ; Biomarkers, Tumor/metabolism ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Cohort Studies ; Female ; Follow-Up Studies ; Hepatectomy ; Humans ; Immunoenzyme Techniques ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Lung Neoplasms/metabolism ; Lung Neoplasms/secondary ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Receptors, CXCR/metabolism ; Survival Rate ; Tissue Array Analysis ; Young Adult ; alpha-Fetoproteins/metabolism
Chemical Substances	ACKR3 protein, human ; Biomarkers, Tumor ; Receptors, CXCR ; alpha-Fetoproteins
Language	English
Publishing date	2011-07-21
Publishing country	Thailand
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2218955-5
ISSN	2476-762X ; 1513-7368
ISSN (online)	2476-762X
ISSN	1513-7368
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Article: [Preliminary application of postoperative fast track transfer to intensive care unit for the geriatric hip fractures under enhanced recovery after surgery].

Xie, T / Rui, Y F / Liu, S Q / Chen, H / Yang, Y / Qiu, X D / Li, H / Li, Q / Chen, C / Huang, Y Z / Ma, B B / Lu, P P / Qi, Y M / Li, R Y / Hu, S Y / Shi, L / Cui, X L / Sun, J / Wang, Z /

Lu, X J / Cui, Y / Zhang, M / Li, Y J / Ren, L Q / Zou, J H / Wang, C

Zhonghua yi xue za zhi

2020 Volume 100, Issue 37, Page(s) 2897–2902

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Aged ; Enhanced Recovery After Surgery ; Hip Fractures/surgery ; Humans ; Intensive Care Units ; Postoperative Period ; Retrospective Studies
Language	Chinese
Publishing date	2020-09-26
Publishing country	China
Document type	Journal Article
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
DOI	10.3760/cma.j.cn112137-20200421-01256
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Zs.B 2011: Show issues

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Article: Flavone C-glycosides from flowers of Trollius ledebouri

Zou, J.H / Yang, J.S / Dong, Y.S / Zhou, L / Lin, G

Phytochemistry. 2005 May, v. 66, no. 10

2005

Abstract: The ethanol extract of the flowers of Trollius ledebouri yielded four flavone C-glycosides, 2"-O-vanilloylvitexin, 2"-O-feruloylorientin, 2"-O-beta-L-galactopyranosylvitexin, and 2"-O-beta-L-galactopyranosylorientin, along with known compounds, 6"-O- ... ...

Abstract	The ethanol extract of the flowers of Trollius ledebouri yielded four flavone C-glycosides, 2"-O-vanilloylvitexin, 2"-O-feruloylorientin, 2"-O-beta-L-galactopyranosylvitexin, and 2"-O-beta-L-galactopyranosylorientin, along with known compounds, 6"-O-acetylorientin, 2"-O-(4'"-hydroxybenzoyl)vitexin, vitexin, and orientin. Their structures were elucidated by means of UV, IR, MS and NMR spectroscopic analyses.
Keywords	Trollius ; plant extracts ; phytochemicals ; flavones ; glycosides ; chemical structure ; spectral analysis ; China
Language	English
Dates of publication	2005-05
Size	p. 1121-1125.
Document type	Article
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
Database	NAL-Catalogue (AGRICOLA)

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