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  1. Article: A systematic review and meta-analysis expounding the relationship between methylene tetrahydrofolate reductase gene polymorphism and the risk of intracerebral hemorrhage among populations.

    Zou, Xue-Lun / Yao, Tian-Xing / Deng, Lu / Chen, Lei / Li, Ye / Zhang, Le

    Frontiers in genetics

    2022  Volume 13, Page(s) 829672

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-08-03
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.829672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Childhood Obesity and Risk of Stroke: A Mendelian Randomisation Analysis.

    Zou, Xue-Lun / Wang, Sai / Wang, Lei-Yun / Xiao, Lin-Xiao / Yao, Tian-Xing / Zeng, Yi / Zhang, Le

    Frontiers in genetics

    2021  Volume 12, Page(s) 727475

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2021-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2021.727475
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Epidemiology of intracerebral hemorrhage: A systematic review and meta-analysis.

    Wang, Sai / Zou, Xue-Lun / Wu, Lian-Xu / Zhou, Hui-Fang / Xiao, Linxiao / Yao, Tianxing / Zhang, Yupeng / Ma, Junyi / Zeng, Yi / Zhang, Le

    Frontiers in neurology

    2022  Volume 13, Page(s) 915813

    Abstract: Background: Intracerebral hemorrhage (ICH) is associated with high mortality and disability rates. This study aimed to investigate the relationship between sex, age, study year, risk factors, bleeding site, median year of study, and the incidence of ICH. ...

    Abstract Background: Intracerebral hemorrhage (ICH) is associated with high mortality and disability rates. This study aimed to investigate the relationship between sex, age, study year, risk factors, bleeding site, median year of study, and the incidence of ICH.
    Method: Literature on the incidence of ICH published on 1 January 1980 and 1 January 2020, was systematically retrieved from PubMed and Embase databases. The random-effects model and subgroup analysis were used to explore the relationship between the incidence of ICH and different ages, sex, bleeding sites, and risk factors.
    Results: We summarized the epidemiological changes in ICH in the past 40 years according to 52 studies and found that the total incidence of ICH is 29.9 per 100,000 person-years (95% CI: 26.5-33.3), which has not decreased worldwide. The incidence of ICH in the Asian population is much higher than in other continents. In addition, the incidence of ICH increases with age and differs at the 85-year-old boundary. Men are more likely to develop ICH than women, and the basal ganglia region is the most common area for ICH. Of the 10 risk factors examined in this study, those with hypertension had the highest incidence of ICH, followed by those with excessive alcohol consumption and heart disease.
    Conclusion: The prevention and treatment of ICH still need to be improved continuously according to age, sex, risk factors, and other factors, and targeted and normative strategies should be gradually developed in the future.
    Language English
    Publishing date 2022-09-16
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2022.915813
    Database MEDical Literature Analysis and Retrieval System OnLINE

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