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  1. Book: Urticaria and Angioedema

    Zuberbier, Torsten / Maurer, Marcus / Grattan, Clive

    2021  

    Abstract: Urticaria is one of the most common diseases in dermatology and allergy. Unlike many other diseases, the ? eeting nature of the wheals makes ? rst diagnosis by both patients and phy- cians in many cases easy. However, this only refers to the ordinary ... ...

    Author's details Torsten Zuberbier is Professor at Charité Berlin and President of the Global Allergy and Asthma European Network (GA²LEN). In addition, he is chairman of the European Centre for Allergy Research Foundation (ECARF). Prof. Zuberbier completed his clinical and scientific education in the field of dermatology at the Charité Virchow Klinikum and wrote his post-doctoral dissertation on the differentiation and function of human mast cells. In 2003, he was appointed Head of Allergy and Co-Director of the Department of Dermatology and Allergy at the Charité Berlin. Prof. Zuberbier¿s research focuses on urticaria since 1990, initiating systematic guidelines from 2000 onwards. Further research interest is, airways allergies, atopic eczema, food allergies and human mast cells. He has published more than 500 papers and is a member of numerous scientific bodies. Clive Grattan, MA, MD, FRCP, is Consultant Dermatologist at St John¿s Institute of Dermatology, London. He has led the difficult urticar
    Abstract Urticaria is one of the most common diseases in dermatology and allergy. Unlike many other diseases, the ? eeting nature of the wheals makes ? rst diagnosis by both patients and phy- cians in many cases easy. However, this only refers to the ordinary wheals. The disease itself is highly complex in nature, with variety of clinical manifestations ranging from pinpoi- sized wheals to extensive angiodema. Complexity is also seen in the diversity of possible eliciting factors, the many different c...
    Keywords Dermatitis ; allergy ; contactdermatitis ; diagnosis ; Inflammation ; Internalmedicine ; itching ; management ; medicine ; physiology ; pressureurticaria ; qualityoflife ; therapy ; treatment ; Urticaria ; contact dermatitis ; inflammation ; internal medicine ; pressure urticaria ; quality of life
    Language English
    Size 264 p.
    Edition 2
    Publisher Springer International Publishing
    Document type Book
    Note PDA Manuell_12
    Format 160 x 241 x 19
    ISBN 9783030845735 ; 3030845737
    Database PDA

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  2. Book ; Online ; E-Book: Allergic diseases - from basic mechanisms to comprehensive management and prevention

    Traidl-Hoffmann, Claudia / Zuberbier, Torsten / Werfel, Thomas

    (Handbook of experimental pharmacology ; 268)

    2022  

    Author's details Claudia Traidl-Hoffmann, Torsten Zuberbier, Thomas Werfel editors
    Series title Handbook of experimental pharmacology ; 268
    Collection
    Keywords Pharmacology
    Subject code 615
    Language English
    Size 1 Online-Ressource (xi, 500 Seiten), Illustrationen, Diagramme
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021292335
    ISBN 978-3-030-84048-8 ; 9783030840471 ; 3-030-84048-4 ; 3030840476
    DOI 10.1007/978-3-030-84048-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Another PROM That Children as Well as Adults Can Use to Monitor Their Chronic Disease.

    Zuberbier, Torsten

    The journal of allergy and clinical immunology. In practice

    2022  Volume 10, Issue 12, Page(s) 3299

    Language English
    Publishing date 2022-12-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2022.09.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Guideline for the definition, classification and diagnosis of urticaria

    Zuberbier, Torsten

    (Česko-slovenská dermatologie ; 82, Suppl. 1)

    2007  

    Title variant Guideline for the management of urticaria ; Diagnostika a léčba urtikárie
    Institution European Dermatology Forum
    Author's details European Dermatology Forum. T. Zuberbier
    Series title Česko-slovenská dermatologie ; 82, Suppl. 1
    Česko-Slovenská dermatologie
    Collection Česko-Slovenská dermatologie
    Language English
    Size S16 S.
    Publishing place Praha
    Publishing country Czech Republic
    Document type Book
    HBZ-ID HT015012957
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: [No title information]

    Zuberbier, Torsten

    Drug research

    2020  Volume 70, Issue S 01, Page(s) S15

    Title translation Arzneimittelreaktion: Allergie vs. Intoleranz gegenüber Wirkstoffen.
    Language German
    Publishing date 2020-11-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-1119-2729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Beyond Allergies-Updates on The Role of Mas-Related G-Protein-Coupled Receptor X2 in Chronic Urticaria and Atopic Dermatitis.

    Lerner, Liron / Babina, Magda / Zuberbier, Torsten / Stevanovic, Katarina

    Cells

    2024  Volume 13, Issue 3

    Abstract: Mast cells (MCs) are an important part of the immune system, responding both to pathogens and toxins, but they also play an important role in allergic diseases, where recent data show that non-IgE-mediated activation is also of relevance, especially in ... ...

    Abstract Mast cells (MCs) are an important part of the immune system, responding both to pathogens and toxins, but they also play an important role in allergic diseases, where recent data show that non-IgE-mediated activation is also of relevance, especially in chronic urticaria (CU) and atopic dermatitis (AD). Skin MCs express Mas-related G-protein-coupled receptor X2 (MRGPRX2), a key protein in non-IgE-dependent MC degranulation, and its overactivity is one of the triggering factors for the above-mentioned diseases, making MRGPRX2 a potential therapeutic target. Reviewing the latest literature revealed our need to focus on the discovery of MRGPRX2 activators as well as the ongoing vast research towards finding specific MRGPRX2 inhibitors for potential therapeutic approaches. Most of these studies are in their preliminary stages, with one drug currently being investigated in a clinical trial. Future studies and improved model systems are needed to verify whether any of these inhibitors may have the potential to be the next therapeutic treatment for CU, AD, and other pseudo-allergic reactions.
    MeSH term(s) Humans ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/metabolism ; Hypersensitivity/metabolism ; Mast Cells/metabolism ; Chronic Urticaria/drug therapy ; Receptors, G-Protein-Coupled/metabolism ; Nerve Tissue Proteins/metabolism ; Receptors, Neuropeptide/metabolism
    Chemical Substances Receptors, G-Protein-Coupled ; MRGPRX2 protein, human ; Nerve Tissue Proteins ; Receptors, Neuropeptide
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells13030220
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Individual wearable air purifier protects against pollen, house dust mite, and cat allergens: Report from an allergen exposure chamber.

    Bergmann, Karl-Christian / Hartung, Teresa / Zuberbier, Torsten

    Allergologie select

    2024  Volume 8, Page(s) 70–77

    Abstract: Purpose: Evaluation of a new individual wearable air purifier (Respiray Wear A+) for birch pollen, house dust mite (HDM), and cat-allergic rhinoconjunctivitis (ARC) patients in a standardized allergen exposure chamber (AEC).: Materials and methods: ... ...

    Abstract Purpose: Evaluation of a new individual wearable air purifier (Respiray Wear A+) for birch pollen, house dust mite (HDM), and cat-allergic rhinoconjunctivitis (ARC) patients in a standardized allergen exposure chamber (AEC).
    Materials and methods: Eligible allergic patients were exposed to birch pollen, HDM raw material, and cat allergen in an AEC for 60 minutes without (V1) and with (V3) the use of the Respiray device. Nasal, ocular, bronchial, and other symptoms were rated by the patients every 10 minutes, and their wellbeing, peak nasal inspiratory flow (PNIF), and lung function parameters were assessed every 30 minutes. The primary endpoint was the change in the median of the total symptom score (TSS) at V3 compared to V1 at 60 minutes of exposure. The secondary endpoints consisted of the total nasal symptom score (TNSS) and total eye symptom score (TESS).
    Results: 23 patients with birch pollen allergy, 37 patients with HDM allergy, and 41 patients with cat allergy were included in the analysis. Significant reduced symptom scores of ~ 49% were observed when using Respiray Wea A+ under birch pollen exposure (p < 0.05) in the primary endpoint TSS (V3 2.43 compared to V1 4.78). An 48% reduction of symptoms was seen in TSS in case of HDM exposure (V3 3.59; V1 6.92, (t-test: p < 0.01)) and the highest reduction of TSS (60%) under Respiray A+ using cat allergens (V3 2.95, V1 7.44, (t-test p < 0.01) after 60 minutes of exposure. The personal wellbeing revealed clinically meaningful improvements over time in all three studies which manifested in a lower symptom increase during the final allergen exposures.
    Conclusion: The individual wearable air purifier Respiray Wear A+ protects significantly against airborne pollen, HDM, and cat allergens and may be a very useful device for avoiding indoor allergens in a new way.
    Language English
    Publishing date 2024-03-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2893503-2
    ISSN 2512-8957 ; 2512-8957
    ISSN (online) 2512-8957
    ISSN 2512-8957
    DOI 10.5414/ALX02473E
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Urticaria and angioedema

    Zuberbier, Torsten / Grattan, Clive / Maurer, Marcus

    2010  

    Author's details Torsten Zuberbier ; Clive Grattan ; Marcus Maurer
    Language English
    Size X, 158 S. : Ill., 24 cm
    Publisher Springer
    Publishing place Heidelberg u.a.
    Publishing country Germany
    Document type Book
    Note Formerly CIP Uk. - Includes bibliographical references and index
    HBZ-ID HT017026816
    ISBN 978-3-540-79047-1 ; 3-540-79047-0 ; 9783540790488 ; 3540790489
    Database Catalogue ZB MED Medicine, Health

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  9. Article: Arzneimittelreaktion: Allergie vs. Intoleranz gegenüber Wirkstoffen

    Zuberbier, Torsten

    Drug Research

    2020  Volume 70, Issue S 01, Page(s) S15–S15

    Language German
    Publishing date 2020-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-1119-2729
    Database Thieme publisher's database

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  10. Article ; Online: Nickel Challenge In Vitro Affects CD38 and HLA-DR Expression in T Cell Subpopulations from the Blood of Patients with Nickel Allergy.

    Artuc, Metin / Zuberbier, Torsten / Peiser, Matthias

    International journal of molecular sciences

    2023  Volume 25, Issue 1

    Abstract: Nickel allergy is a major health problem and shows clinical manifestation of contact eczema. The response of specific lymphocyte subpopulations in sensitized patients after new challenge to nickel has until now not been studied in detail. To evaluate if ... ...

    Abstract Nickel allergy is a major health problem and shows clinical manifestation of contact eczema. The response of specific lymphocyte subpopulations in sensitized patients after new challenge to nickel has until now not been studied in detail. To evaluate if nickel-based elicitation reaction could be objectively identified by multi-parametric flow cytometry, immunophenotyping of specific T cells was applied. White blood cells from 7 patients (4 positive in patch test, 3 negative) were challenged by nickel and in vitro short-term culture. Standardized antibody-dye combinations, specific for T helper(h)1, Th17 and cytotoxic T cell activation, were selected according to the recommendations of Stanford Human Immune Monitoring Center. In cytotoxic CD8
    MeSH term(s) Humans ; Nickel/adverse effects ; Receptors, CCR7 ; Hypersensitivity ; HLA-DR Antigens
    Chemical Substances Nickel (7OV03QG267) ; Receptors, CCR7 ; HLA-DR Antigens
    Language English
    Publishing date 2023-12-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25010298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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