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  1. Article ; Online: Validation of manual to complement the transition of care at discharge from intensive care.

    Zucchetti, Martina / Severo, Isis Marques / Echer, Isabel Cristina / Borba, Daniela Dos Santos Marona / Nectoux, Carmen Lucia Silva / Azzolin, Karina de Oliveira

    Revista gaucha de enfermagem

    2022  Volume 43, Issue spe, Page(s) e20220142

    Abstract: Objective: To develop and validate an interprofessional manual for the transfer of care to critically ill adult patients.: Method: Methodological study, conducted from January to September 2019. The content of the manual was listed by the ... ...

    Abstract Objective: To develop and validate an interprofessional manual for the transfer of care to critically ill adult patients.
    Method: Methodological study, conducted from January to September 2019. The content of the manual was listed by the multidisciplinary team of an adult Intensive Care Unit, in southern Brazil. In the validation by the professionals, the content validity index (CVI) of the evaluation questions was calculated. Subsequently, a sample of 30 patients/caregivers evaluated the product, and the arithmetic mean of the questions was calculated.
    Results: The manual addresses important information and care transition guidance for patients and caregivers, from admission to the intensive care to discharge to the inpatient unit. The professionals' CVI ranged from 0.9 to 1. The arithmetic mean of 17 patients and 13 caregivers was 3.8.
    Final considerations: The validated manual can be used as a complementary material for health education and qualify the transition of care.
    MeSH term(s) Adult ; Humans ; Patient Discharge ; Patient Transfer ; Critical Care ; Body Fluids ; Intensive Care Units
    Language Portuguese
    Publishing date 2022-11-28
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2639673-7
    ISSN 1983-1447 ; 1983-1447
    ISSN (online) 1983-1447
    ISSN 1983-1447
    DOI 10.1590/1983-1447.2022.20220142.en
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A left atrial appendage closure combined procedure review: Past, present, and future perspectives.

    Gasperetti, Alessio / Fassini, Gaetano / Tundo, Fabrizio / Zucchetti, Martina / Dessanai, Mariantonietta / Tondo, Claudio

    Journal of cardiovascular electrophysiology

    2019  Volume 30, Issue 8, Page(s) 1345–1351

    Abstract: Background and objective: Atrial fibrillation (AF) represents the most common cardiac arrhythmia worldwide; it poses a great burden in terms of quality of life reduction and yearly stroke risk. Left atrial appendage closure (LAAC) is a stroke prevention ...

    Abstract Background and objective: Atrial fibrillation (AF) represents the most common cardiac arrhythmia worldwide; it poses a great burden in terms of quality of life reduction and yearly stroke risk. Left atrial appendage closure (LAAC) is a stroke prevention strategy that has been proven a viable alternative to antithrombotic regimens in nonvalvular AF patients. LAAC can be performed as a standalone procedure or alongside a concomitant AF transcatheter ablation, in a procedure known as "Combined procedure". Aim of this study is to summarize the scientific evidence backing this combined strategy.
    Methods: We reviewed the whole Medline indexed combined procedure literature, to summarize all the combined procedure study data.
    Results: Nine published studies regarding combined procedure were found. Data, aims, and scientific rationales were reported and commented.
    Conclusion: LAA combined procedure appears to be a safe and effective procedure; a careful patient selection is necessary to maximize its benefit.
    MeSH term(s) Action Potentials ; Atrial Appendage/physiopathology ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/physiopathology ; Atrial Fibrillation/therapy ; Atrial Function, Left ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/instrumentation ; Cardiac Catheterization/trends ; Catheter Ablation/adverse effects ; Catheter Ablation/instrumentation ; Catheter Ablation/trends ; Clinical Decision-Making ; Combined Modality Therapy ; Cryosurgery/adverse effects ; Cryosurgery/instrumentation ; Cryosurgery/trends ; Diffusion of Innovation ; Forecasting ; Heart Rate ; Humans ; Patient Selection ; Risk Assessment ; Risk Factors ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/physiopathology ; Stroke/prevention & control ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2019-05-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.13957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An ablation index operator-independent approach to improve efficacy in atrial fibrillation ablation at 24-month follow-up: a single center experience.

    Casella, Michela / Dello Russo, Antonio / Riva, Stefania / Catto, Valentina / Negro, Gabriele / Sicuso, Rita / Cellucci, Selene / Gasperetti, Alessio / Zucchetti, Martina / Ribatti, Valentina / Biagioli, Viviana / Fassini, Gaetano / Di Biase, Luigi / Natale, Andrea / Tondo, Claudio

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2019  Volume 57, Issue 2, Page(s) 241–249

    Abstract: Purpose: Since the introduction of catheter ablation as a mainstream treatment for atrial fibrillation (AF), several technical improvements have been put forward. In this contest, Ablation Index (AI) is an accurate ablation quality marker by ... ...

    Abstract Purpose: Since the introduction of catheter ablation as a mainstream treatment for atrial fibrillation (AF), several technical improvements have been put forward. In this contest, Ablation Index (AI) is an accurate ablation quality marker by incorporating power, delivery time, contact force (CF), and catheter stability in a weighted formula. The aim of our study is to evaluate the efficacy of AI-guided AF ablation over 24 month follow-up.
    Methods: We evaluated 72 consecutive patients with drug-refractory paroxysmal (66.7%) and early-persistent AF (33.3%) undergoing AI-guided ablation, compared to 72 propensity-matched control patients who underwent CF-guided procedure. All procedures were performed by three skilled operators. Data concerning procedural characteristics and long-term freedom from AF recurrence were analyzed.
    Results: At 24-month follow-up, Kaplan-Meier curves of AF recurrence were significantly lower in AI group than in CF group (15.5% vs. 30.6%; p 0.042). These findings were confirmed in a sub analysis regardless of the continued use of antiarrhythmic drugs in the follow-up (42.2% in AI-guided group and 66.7% in CF-guided group, p 0.004). At 24-month follow-up, a positive trend in the decrease of arrhythmia recurrences was observed in AI-guided ablation for all operators.
    Conclusions: AI-guided ablation results more effective than CF-guided ablation as demonstrated by a lower incidence of AF recurrences regardless of the use of antiarrhythmic drugs in the follow-up. Each operator seems to improve the long-term success using an AI-guided ablation, thus showing both the efficacy and the reproducibility of this approach.
    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation/standards ; Female ; Humans ; Male ; Middle Aged ; Propensity Score ; Prospective Studies ; Quality Improvement ; Quality Indicators, Health Care ; Reproducibility of Results
    Language English
    Publishing date 2019-07-16
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-019-00587-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Acute outcome after a single cryoballoon ablation: Comparison between Arctic Front Advance and Arctic Front Advance PRO.

    Moltrasio, Massimo / Sicuso, Rita / Fassini, Gaetano M / Riva, Stefania I / Tundo, Fabrizio / Dello Russo, Antonio / Casella, Michela / Majocchi, Benedetta / Zucchetti, Martina / Cellucci, Selene / Tondo, Claudio

    Pacing and clinical electrophysiology : PACE

    2019  Volume 42, Issue 7, Page(s) 890–896

    Abstract: Background: The novel fourth-generation cryoballoon (CB4) potentially allows for enhanced catheter maneuverability and more frequent capture of pulmonary vein (PV) potentials which can be used to monitor real-time PV isolation (PVI). The aim of our ... ...

    Abstract Background: The novel fourth-generation cryoballoon (CB4) potentially allows for enhanced catheter maneuverability and more frequent capture of pulmonary vein (PV) potentials which can be used to monitor real-time PV isolation (PVI). The aim of our study is to compare the acute procedural endpoints between the CB4 and second-generation cryoballoon (CB2).
    Methods: A single-center retrospective chart review was used to examine 50 consecutive patients with drug-refractory atrial fibrillation undergoing CB4-based PVI. Procedural data and acute success of these patients were compared to 50 propensity-matched controls who underwent cryoballoon ablation procedure using CB2.
    Results: Procedures performed with the CB4 showed significant shorter fluoroscopy time (14.8 ± 5.5 vs 18.0 ± 6.5 minutes, P = .04), shorter procedure time (58.3 ± 15.7 vs 65.3 ± 21 minutes, P = .13), and shorter total ablation time (10.8 ± 1.5 vs 13.8 ± 1.9 minutes, P = .42). The real-time PVI visualization rate was 33.3% in the CB2 group and 74.7% in the CB4 group (P < .001). CB4 was correlated to significant increase of acute real-time recordings with regard to all the single PV (left superior PV: 58% vs 84%, P = .02; left inferior PV: 26% vs 71%, P = .001; right superior PV 29% vs 61%, P = .01; and right inferior PV 19% vs 58%, P = .002).
    Conclusion: The CB4 was more often able to capture real-time recordings of PV potentials and the subsequent acute PV isolation.
    MeSH term(s) Atrial Fibrillation/surgery ; Balloon Occlusion/instrumentation ; Cryosurgery/instrumentation ; Female ; Fluoroscopy ; Humans ; Male ; Middle Aged ; Operative Time ; Propensity Score ; Pulmonary Veins/surgery ; Retrospective Studies
    Language English
    Publishing date 2019-05-15
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.13718
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  5. Article ; Online: Long-Term Outcomes of Near-Zero Radiation Ablation of Paroxysmal Supraventricular Tachycardia: A Comparison With Fluoroscopy-Guided Approach.

    Bergonti, Marco / Dello Russo, Antonio / Sicuso, Rita / Ribatti, Valentina / Compagnucci, Paolo / Catto, Valentina / Gasperetti, Alessio / Zucchetti, Martina / Cellucci, Selene / Vettor, Giulia / Dessanai, Maria Antonietta / Majocchi, Benedetta / Moltrasio, Massimo / Russo, Eleonora / Stronati, Giulia / Guerra, Federico / Di Biase, Luigi / Natale, Andrea / Tondo, Claudio /
    Casella, Michela

    JACC. Clinical electrophysiology

    2021  Volume 7, Issue 9, Page(s) 1108–1117

    Abstract: Objectives: This study aimed to assess the long-term outcomes of minimally fluoroscopic approach (MFA) compared with conventional fluoroscopic ablation (ConvA) in terms of recurrences of arrhythmia and long-term complications.: Background: Catheter ... ...

    Abstract Objectives: This study aimed to assess the long-term outcomes of minimally fluoroscopic approach (MFA) compared with conventional fluoroscopic ablation (ConvA) in terms of recurrences of arrhythmia and long-term complications.
    Background: Catheter ablation (CA) of supraventricular tachycardia (SVT) with an MFA, under the guidance of electroanatomic mapping (EAM) systems, results in a significant reduction in exposure to ionizing radiations without impairing acute procedural success and complication rate. However, data regarding long-term outcomes of MFA compared with ConvA are lacking.
    Methods: This is a retrospective observational study. All patients undergoing MFA CA of SVT (atrioventricular nodal re-entrant tachycardia and atrioventricular re-entrant tachycardia) between 2010 and 2015 were enrolled and were compared with matched subjects (1 MFA: 2 ConvA) undergoing ConvA during the same period. The 2 co-primary outcomes were recurrence of arrhythmias and long-term complications.
    Results: A total of 618 patients (mean age 38 ± 15 years, 60% female) were enrolled. MFA included 206 patients, whereas 412 were treated with ConvA. Acute success (99% vs. 97%; p = 0.10) and acute complications (2.4% vs. 5.3%; p = 0.14) were similar in the 2 groups. During a median follow-up of 4.4 years, 5.9% of patients experienced recurrence of arrhythmias. At multivariate analysis, ConvA (hazard ratio [HR]: 3.03) and procedural success (HR: 0.10) were independently associated with recurrence of arrhythmias. Late complications (i.e., advance atrioventricular block and need for pacemaker implantation) occurred more frequently in ConvA (3.4% vs. 0.5%; p = 0.03) compared with MFA.
    Conclusions: CA guided by EAM systems with MFA provided better long-term results and reduced risk of complications compared with ConvA.
    MeSH term(s) Adult ; Catheter Ablation ; Female ; Fluoroscopy ; Humans ; Male ; Middle Aged ; Tachycardia, Supraventricular/surgery ; Tachycardia, Ventricular ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2021-04-28
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2021.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Difficult case of a trans-septal puncture: Use of a "SafeSept" guidewire.

    Zucchetti, Martina / Casella, Michela / DelloRusso, Antonio / Fassini, Gaetano / Carbucicchio, Corrado / Russo, Eleonora / Marino, Vittoria / Catto, Valentina / Tondo, Claudio

    World journal of cardiology

    2015  Volume 7, Issue 8, Page(s) 499–503

    Abstract: A 69-year-old man was admitted to our center to undergo catheter ablation of paroxysmal atrial fibrillation refractory to antiarrhythmic drug therapy. This procedure required access to the left atrium through the interatrial septum. During ... ...

    Abstract A 69-year-old man was admitted to our center to undergo catheter ablation of paroxysmal atrial fibrillation refractory to antiarrhythmic drug therapy. This procedure required access to the left atrium through the interatrial septum. During hospitalization, the patient performed routinely pre-procedure transthoracic echocardiography and gadolinium-enhanced cardiac magnetic resonance showing a normal anatomy of both the fossa ovalis and the interatrial septum. Access to the left atrium proved difficult and several unsuccessful attempts to perform the trans-septal puncture were made under both fluoroscopy and intracardiac echocardiography guidance, even with radiofrequency energy delivery. Finally, trans-septal puncture was successfully carried out using a novel nitinol J-shaped "SafeSept" trans-septal guidewire, designed to cross the interatrial septum through the trans-septal needle thanks to a special sharp tip. Moreover, thanks to its rounded J shape that reduces the risk of atrial perforation, the "SafeSept" guidewire, when advanced into the left atrium, becomes atraumatic.
    Language English
    Publishing date 2015-08-17
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2573665-6
    ISSN 1949-8462
    ISSN 1949-8462
    DOI 10.4330/wjc.v7.i8.499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Concomitant cryoballoon ablation and percutaneous closure of left atrial appendage in patients with atrial fibrillation.

    Fassini, Gaetano / Conti, Sergio / Moltrasio, Massimo / Maltagliati, Anna / Tundo, Fabrizio / Riva, Stefania / Dello Russo, Antonio / Casella, Michela / Majocchi, Benedetta / Zucchetti, Martina / Russo, Eleonora / Marino, Vittoria / Pepi, Mauro / Tondo, Claudio

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2016  Volume 18, Issue 11, Page(s) 1705–1710

    Abstract: Aims: Pulmonary veins (PVs) isolation is the cornerstone of atrial fibrillation (AF) ablation and can be achieved either by conventional radiofrequency ablation or by cryoenergy. Left atrial appendage (LAA) closure has been proposed as alternative ... ...

    Abstract Aims: Pulmonary veins (PVs) isolation is the cornerstone of atrial fibrillation (AF) ablation and can be achieved either by conventional radiofrequency ablation or by cryoenergy. Left atrial appendage (LAA) closure has been proposed as alternative treatment to vitamin K antagonists (VKA). We aimed to evaluate the feasibility of combining cryoballoon (CB) ablation and LAA occlusion in patients with AF and a high thromboembolic risk or contraindication to antithrombotic therapy.
    Methods and results: Thirty-five patients (28 males, 74 ± 2 years) underwent CB ablation. Left atrial appendage occlusion was carried out by using two occluder devices (Amplatz Cardiac Plug, ACP, St. Jude Medical, MN, USA, in 25 patients; Watchman, Boston Scientific, MA, USA, in 10 patients). Thirty patients (86%) had previous stroke/TIA episodes, 6 patients (17%) had major bleeding while on VKA therapy, and 7 patients (20%) had inherited bleeding disorders. Over the follow-up (24 ± 12 months), atrial arrhythmias recurred in 10 (28%) patients. Thirty patients (86%) had complete sealing; 5 patients (14%) showed a residual flow (<5 mm) at first transoesophageal echocardiography (TEE) check, while at 1-year TEE residual flow was detected in 3 patients. In 13 patients (37%), VKA therapy was immediately discontinued. Six patients (17%) received novel oral anticoagulants treatment and then discontinued 3 months thereafter. No device-related complications or clinical thromboembolic events occurred.
    Conclusion: Combined CB ablation and LAA closure using different devices appears to be feasible in patients with non-valvular AF associated with high risk of stroke or contraindication to antithrombotic treatment.
    MeSH term(s) Aged ; Anticoagulants/administration & dosage ; Atrial Appendage/surgery ; Atrial Fibrillation/therapy ; Catheter Ablation/methods ; Echocardiography, Three-Dimensional ; Female ; Follow-Up Studies ; Hemorrhage/etiology ; Humans ; Male ; Prospective Studies ; Pulmonary Veins/surgery ; Recurrence ; Septal Occluder Device ; Stroke/etiology ; Treatment Outcome ; United States
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2016-11
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euw007
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  8. Article: Idiopathic Ventricular Tachycardia: Transcatheter Ablation or Antiarrhythmic Drugs?

    Tondo, Claudio / Carbucicchio, Corrado / Dello Russo, Antonio / Majocchi, Benedetta / Zucchetti, Martina / Pizzamiglio, Francesca / Bologna, Fabrizio / Cattaneo, Fabio / Colombo, Daniele / Russo, Eleonora / Casella, Michela

    Journal of atrial fibrillation

    2015  Volume 7, Issue 5, Page(s) 1164

    Abstract: Introduction: Ventricular tachycardia or frequent premature ventricular contractions (PVCs) can occur in the absence of any detectable structural heart disease. In this clinical setting, these arrhythmias are termed idiopathic. Usually, they carry a ... ...

    Abstract Introduction: Ventricular tachycardia or frequent premature ventricular contractions (PVCs) can occur in the absence of any detectable structural heart disease. In this clinical setting, these arrhythmias are termed idiopathic. Usually, they carry a benign prognosis and any potential ablative intervention is carried out if patients are highly symptomatic or, more importantly, if frequent ventricular arrhythmias can lead to ventricular dysfunction.
    Methods: In this paper, different forms of idiopathic ventricular tachycardia are reviewed. Outflow tract ventricular tachycardia from the right ventricle is the most frequent form of the so-called idiopathic ventricular tachycardia. Other forms of idiopathic ventricular arrhythmias include ventricular tachycardia/PVCs arising from tricuspid annulus, from the mitral annulus, inter-fascicular ventricular tachycardia and papillary muscle ventricular tachycardia. When interventional treatment is deemed necessary, detailed mapping ( earliest activation during VT/PVC, pace mapping ) is crucial as to identify the successful ablation site. Catheter ablation more than antiarrhythmic drug treatment is usually highly effective in eliminating idiopathic ventricular arrhythmias and providing prevention of recurrence.
    Conclusions: Idiopathic VTs are not considered life-threatening arrhythmias and, prevention of recurrences is often achieved by means of catheter ablation that provides an improvement of quality of life. The overall acute success rate of catheter ablation is about 85-90% with a long-term prevention of arrhythmia recurrence of about 75-80%. It is advisable that the procedure is carried out by electrophysiologists with expertise in VT catheter ablation and extensive knowledge of cardiac anatomy as to ensure a high success rate and reduce the likelihood of major complications.
    Language English
    Publishing date 2015-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2451936-4
    ISSN 1941-6911
    ISSN 1941-6911
    DOI 10.4022/jafib.1164
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  9. Article: Electrical storm: A clinical and electrophysiological overview.

    Conti, Sergio / Pala, Salvatore / Biagioli, Viviana / Del Giorno, Giuseppe / Zucchetti, Martina / Russo, Eleonora / Marino, Vittoria / Dello Russo, Antonio / Casella, Michela / Pizzamiglio, Francesca / Catto, Valentina / Tondo, Claudio / Carbucicchio, Corrado

    World journal of cardiology

    2015  Volume 7, Issue 9, Page(s) 555–561

    Abstract: Electrical storm (ES) is a clinical condition characterized by three or more ventricular arrhythmia episodes leading to appropriate implantable cardioverter-defibrillator (ICD) therapies in a 24 h period. Mostly, arrhythmias responsible of ES are ... ...

    Abstract Electrical storm (ES) is a clinical condition characterized by three or more ventricular arrhythmia episodes leading to appropriate implantable cardioverter-defibrillator (ICD) therapies in a 24 h period. Mostly, arrhythmias responsible of ES are multiple morphologies of monomorphic ventricular tachycardia (VT), but polymorphic VT and ventricular fibrillation can also result in ES. Clinical presentation is very dramatic in most cases, strictly related to the cardiac disease that may worsen electrical and hemodynamic decompensation. Therefore ES management is challenging in the majority of cases and a high mortality is the rule both in the acute and in the long-term phases. Different underlying cardiomyopathies provide significant clues into the mechanism of ES, which can arise in the setting of structural arrhythmogenic cardiomyopathies or rarely in patients with inherited arrhythmic syndrome, impacting on pharmacological treatment, on ICD programming, and on the opportunity to apply strategies of catheter ablation. This latter has become a pivotal form of treatment due to its high efficacy in modifying the arrhythmogenic substrate and in achieving rhythm stability, aiming at reducing recurrences of ventricular arrhythmia and at improving overall survival. In this review, the most relevant epidemiological and clinical aspects of ES, with regard to the acute and long-term follow-up implications, were evaluated, focusing on these novel therapeutic strategies of treatment.
    Language English
    Publishing date 2015-07-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2573665-6
    ISSN 1949-8462
    ISSN 1949-8462
    DOI 10.4330/wjc.v7.i9.555
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  10. Article ; Online: X-Ray Exposure in Cardiac Electrophysiology: A Retrospective Analysis in 8150 Patients Over 7 Years of Activity in a Modern, Large-Volume Laboratory.

    Casella, Michela / Dello Russo, Antonio / Russo, Eleonora / Catto, Valentina / Pizzamiglio, Francesca / Zucchetti, Martina / Majocchi, Benedetta / Riva, Stefania / Vettor, Giulia / Dessanai, Maria Antonietta / Fassini, Gaetano / Moltrasio, Massimo / Tundo, Fabrizio / Vignati, Carlo / Conti, Sergio / Bonomi, Alice / Carbucicchio, Corrado / Di Biase, Luigi / Natale, Andrea /
    Tondo, Claudio

    Journal of the American Heart Association

    2018  Volume 7, Issue 11

    Abstract: Background: Only a few studies have systematically evaluated fluoroscopy data of electrophysiological and device implantation procedures. Aims of this study were to quantify ionizing radiation exposure for electrophysiological/device implantation ... ...

    Abstract Background: Only a few studies have systematically evaluated fluoroscopy data of electrophysiological and device implantation procedures. Aims of this study were to quantify ionizing radiation exposure for electrophysiological/device implantation procedures in a large series of patients and to analyze the x-ray exposure trend over years and radiation exposure in patients undergoing atrial fibrillation ablation considering different technical aspects.
    Methods and results: We performed a retrospective analysis of all electrophysiological/device implantation procedures performed during the past 7 years in a modern, large-volume laboratory. We reported complete fluoroscopy data on 8150 electrophysiological/device implantation procedures (6095 electrophysiological and 2055 device implantation procedures); for each type of procedure, effective dose and lifetime attributable risk of cancer incidence and mortality were calculated. Over the 7-year period, we observed a significant trend reduction in fluoroscopy time, dose area product, and effective dose for all electrophysiological procedures (
    Conclusions: Electrophysiological procedures involve a nonnegligible x-ray use, leading to an increased risk of malignancy. Awareness of radiation-related risk, together with technological advances, can successfully optimize fluoroscopy use.
    MeSH term(s) Aged ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/therapy ; Cardiac Catheterization/adverse effects ; Catheter Ablation/adverse effects ; Cryosurgery/adverse effects ; Electrophysiologic Techniques, Cardiac/adverse effects ; Female ; Fluoroscopy/adverse effects ; Humans ; Male ; Middle Aged ; Occupational Exposure/adverse effects ; Occupational Health ; Operative Time ; Prosthesis Implantation/adverse effects ; Radiation Dosage ; Radiation Exposure/adverse effects ; Radiography, Interventional/adverse effects ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors
    Language English
    Publishing date 2018-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.117.008233
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