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  1. Book ; Conference proceedings: DIZZYNET 2019: approaching the future of vestibular research

    Zwergal, Andreas

    (Journal of neurology ; volume 266, supplement 1 (September 2019))

    2019  

    Event/congress DIZZYNET Meeting (5., 2018, Starnberg)
    Author's details guest editors: Andreas Zwergal, Eva Grill, Christophe Lopez, Marianne Dieterich
    Series title Journal of neurology ; volume 266, supplement 1 (September 2019)
    Collection
    Language English
    Size A8, S159 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Conference proceedings
    HBZ-ID HT020233026
    Database Catalogue ZB MED Medicine, Health

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  2. Book: DIZZYNET 2018: visions and perspectives in future vestibular research

    Zwergal, Andreas

    (Journal of neurology ; volume 265, supplement 1 (October 2018))

    2018  

    Title variant Visions and perspectives in future vestibular research
    Institution DIZZYNET - The European Network for Vertigo and Balance Research
    Author's details guest editors: Andreas Zwergal, Thomas Brandt, Hans Straka, Dominik Straumann, Marianne Dieterich
    Series title Journal of neurology ; volume 265, supplement 1 (October 2018)
    Collection
    Language English
    Size S133 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book
    HBZ-ID HT019889871
    Database Catalogue ZB MED Medicine, Health

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  3. Book: DIZZYNET - The European Network for Vertigo and Balance Research

    Zwergal, Andreas

    (Journal of neurology ; volume 263, supplement 1 (April 2016))

    2016  

    Institution DIZZYNET - The European Network for Vertigo and Balance Research
    Author's details guest editors: Andreas Zwergal, Thomas Brandt, Mans Magnusson, Christopher Kennard
    Series title Journal of neurology ; volume 263, supplement 1 (April 2016)
    Collection
    Language English
    Size S96 Seiten, Illustrationen
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book
    HBZ-ID HT019003181
    Database Catalogue ZB MED Medicine, Health

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  4. Book: DIZZYNET 2017 - The vestibular system: sensory, motor and cognitive functions

    Dieterich, Marianne / Zwergal, Andreas

    in honor of Marianne Dieterich

    (Journal of neurology ; volume 264, supplement 1 (October 2017))

    2017  

    Title variant The vestibular system: sensory, motor and cognitive functions
    Institution DIZZYNET - The European Network for Vertigo and Balance Research
    Author's details guest editors: Andreas Zwergal, Hans Straka, Thomas Brandt, Michael Strupp
    Series title Journal of neurology ; volume 264, supplement 1 (October 2017)
    Collection
    Language English
    Size S103 Seiten, Illustrationen, Diagramme
    Publisher Springer
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book
    Note Based on talks and posters presented at a conference in Hohenkammer, Bavaria, Germany, on October 20-22, 2016
    HBZ-ID HT019482676
    Database Catalogue ZB MED Medicine, Health

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  5. Book ; Thesis: Molekulare Mechanismen der TNF-induzierten Toleranz

    Zwergal, Andreas

    2007  

    Author's details Andreas Zwergal
    Language German
    Size 85 BL., graph. Darst., 30 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Techn. Univ., Diss., 2007
    HBZ-ID HT015732065
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Conference proceedings: Ginkgo-biloba-Extrakte: multimodale Wirkung bei Schwindelerkrankungen

    Zwergal, Andreas

    Zeitschrift für Phytotherapie

    2022  Volume 43, Issue S 01

    Event/congress Phytotherapie 2022 - innovativ: Abstracts der Poster, Zürich, 2022-06-16
    Language German
    Publishing date 2022-06-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 2201963-7
    ISSN 1438-9584 ; 0722-348X
    ISSN (online) 1438-9584
    ISSN 0722-348X
    DOI 10.1055/s-0042-1749472
    Database Thieme publisher's database

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  7. Article ; Online: Histaminergic System and Vestibular Function in Normal and Pathological Conditions.

    Tighilet, Brahim / Trico, Jessica / Marouane, Emna / Zwergal, Andreas / Chabbert, Christian

    Current neuropharmacology

    2024  

    Abstract: Most neurotransmitter systems are represented in the central and peripheral vestibular system and are thereby involved both in normal vestibular signal processing and the pathophysiology of vestibular disorders. However, there is a special relationship ... ...

    Abstract Most neurotransmitter systems are represented in the central and peripheral vestibular system and are thereby involved both in normal vestibular signal processing and the pathophysiology of vestibular disorders. However, there is a special relationship between the vestibular system and the histaminergic system. The purpose of this review is to document how the histaminergic system interferes with normal and pathological vestibular function. In particular, we will discuss neurobiological mechanisms such as neuroinflammation that involve histamine to modulate and allow restoration of balance function in the situation of a vestibular insult. These adaptive mechanisms represent targets of histaminergic pharmacological compounds capable of restoring vestibular function in pathological situations. The clinical use of drugs targeting the histaminergic system in various vestibular disorders is critically discussed.
    Language English
    Publishing date 2024-03-19
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X22666240319123151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Vestibular contribution to spatial orientation and navigation.

    Zwergal, Andreas / Grabova, Denis / Schöberl, Florian

    Current opinion in neurology

    2023  Volume 37, Issue 1, Page(s) 52–58

    Abstract: Purpose of review: The vestibular system provides three-dimensional idiothetic cues for updating of one's position in space during head and body movement. Ascending vestibular signals reach entorhinal and hippocampal networks via head-direction pathways, ...

    Abstract Purpose of review: The vestibular system provides three-dimensional idiothetic cues for updating of one's position in space during head and body movement. Ascending vestibular signals reach entorhinal and hippocampal networks via head-direction pathways, where they converge with multisensory information to tune the place and grid cell code.
    Recent findings: Animal models have provided insight to neurobiological consequences of vestibular lesions for cerebral networks controlling spatial cognition. Multimodal cerebral imaging combined with behavioural testing of spatial orientation and navigation performance as well as strategy in the last years helped to decipher vestibular-cognitive interactions also in humans.
    Summary: This review will update the current knowledge on the anatomical and cellular basis of vestibular contributions to spatial orientation and navigation from a translational perspective (animal and human studies), delineate the behavioural and functional consequences of different vestibular pathologies on these cognitive domains, and will lastly speculate on a potential role of vestibular dysfunction for cognitive aging and impeding cognitive impairment in analogy to the well known effects of hearing loss.
    MeSH term(s) Animals ; Humans ; Orientation, Spatial ; Space Perception ; Vestibule, Labyrinth ; Cognition ; Cues
    Language English
    Publishing date 2023-11-27
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1182686-1
    ISSN 1473-6551 ; 1350-7540
    ISSN (online) 1473-6551
    ISSN 1350-7540
    DOI 10.1097/WCO.0000000000001230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Die sechs häufigsten peripheren vestibulären Syndrome.

    Strupp, Michael Leo / Zwergal, Andreas / Goldschagg, Nicolina

    Laryngo- rhino- otologie

    2023  Volume 103, Issue 3, Page(s) 196–206

    Abstract: Three forms of peripheral vestibular disorders, each with its typical symptoms and clinical signs, can be differentiated functionally, anatomically and pathophysiologically: 1. inadequate unilateral paroxysmal stimulation or rarely inhibition of the ... ...

    Title translation The six most frequent peripheral vestibular syndromes.
    Abstract Three forms of peripheral vestibular disorders, each with its typical symptoms and clinical signs, can be differentiated functionally, anatomically and pathophysiologically: 1. inadequate unilateral paroxysmal stimulation or rarely inhibition of the peripheral vestibular system, e. g., BPPV, Menière's disease, vestibular paroxysmia or syndrome of the third mobile windows; 2. acute unilateral vestibulopathy leading to an acute vestibular tone imbalance manifesting as an acute peripheral vestibular syndrome; and 3. loss or impairment of function of the vestibular nerve and/or labyrinth: bilateral vestibulopathy. For all of these diseases, current diagnostic criteria by the Bárány-Society are available with a high clinical and scientific impact, also for clinical trials. The treatment depends on the underlying disease. It basically consists of 5 principles: 1. Explaining the symptoms and signs, pathophysiology, aetiology and treatment options to the patient; this is important for compliance, adherence and persistence. 2. Physical therapy: A) For BPPV specific liberatory maneuvers, depending on canal involved. Posterior canal: The new SémontPLUS maneuver is superior to the regular Sémont and Epley maneuvers; horizontal canal: the modified roll-maneuver; anterior canal the modified Yacovino-maneuver; 3. Symptomatic or causative drug therapy. There is still a deficit of placebo-controlled clinical trials so that the level of evidence for pharmacotherapy is most often low. 4. Surgery, mainly for the syndrome of the third mobile windows. 5. Psychotherapeutic measures for secondary functional dizziness.
    MeSH term(s) Humans ; Vestibular Diseases/diagnosis ; Vestibular Diseases/therapy ; Vertigo/diagnosis ; Vertigo/etiology ; Vertigo/therapy ; Meniere Disease/diagnosis ; Meniere Disease/therapy ; Bilateral Vestibulopathy ; Acute Disease ; Vestibule, Labyrinth
    Language German
    Publishing date 2023-12-22
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0340-1588 ; 0935-8943
    ISSN (online) 1438-8685
    ISSN 0340-1588 ; 0935-8943
    DOI 10.1055/a-2144-3801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Aktuelles zu den häufigen Schwindelsyndromen: Diagnostik und Therapie.

    Zwergal, Andreas / Dieterich, Marianne

    Fortschritte der Neurologie-Psychiatrie

    2021  Volume 89, Issue 5, Page(s) 211–220

    Abstract: The 8 most frequent vestibular disorders account for more than 70% of all presentations of vertigo, dizziness, and imbalance. In acute (and mostly non-repetitive) vestibular disorders acute unilateral vestibulopathy and vestibular stroke are most ... ...

    Title translation Update on diagnosis and therapy in frequent vestibular and balance disorders.
    Abstract The 8 most frequent vestibular disorders account for more than 70% of all presentations of vertigo, dizziness, and imbalance. In acute (and mostly non-repetitive) vestibular disorders acute unilateral vestibulopathy and vestibular stroke are most important, in episodic vestibulopathies benign paroxysmal positional vertigo (BPPV), Menière's disease and vestibular migraine, and in chronic vestibular disorders bilateral vestibulopathy/presbyvestibulopathy, functional dizziness and cerebellar dizziness. In the last decade, internationally consented diagnostic criteria and nomenclature were established for the most frequent vestibular disorders, which can be easily applied in clinical practice. The diagnostic guidelines are based on history taking (including onset, duration, course, triggers, accomanying symptoms), clinical examination, and only a few apparative tests (by videooculography and audiometry) for securing the diagnosis. Treatment of vestibular disorders includes physical training (repositioning maneuvers, multimodal balance training) and pharmacological approaches (e.g., corticosteroids, antiepileptics, antidepressants, potassium-canal-blockers, drugs enhancing neuroplasticity). For most drugs, high-level evidence from prospective controlled trials is lacking. In clinical practice, the most frequent vestibular disorders can be treated effectively, thus avoiding chronicity and secondary comorbidity (by immobility, falls or psychiatric disorders such as anxiety or depression).
    MeSH term(s) Dizziness ; Humans ; Migraine Disorders ; Prospective Studies ; Vertigo/diagnosis ; Vertigo/epidemiology ; Vertigo/therapy ; Vestibular Diseases/diagnosis ; Vestibular Diseases/therapy
    Language German
    Publishing date 2021-04-19
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 625328-3
    ISSN 1439-3522 ; 0720-4299
    ISSN (online) 1439-3522
    ISSN 0720-4299
    DOI 10.1055/a-1432-1849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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