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  1. Book ; Online: Introducing a Framework and a Decision Protocol to Calibrate Recommender Systems

    da Silva, Diego Corrêa / Durão, Frederico Araújo

    2022  

    Abstract: Recommender Systems use the user's profile to generate a recommendation list with unknown items to a target user. Although the primary goal of traditional recommendation systems is to deliver the most relevant items, such an effort unintentionally can ... ...

    Abstract Recommender Systems use the user's profile to generate a recommendation list with unknown items to a target user. Although the primary goal of traditional recommendation systems is to deliver the most relevant items, such an effort unintentionally can cause collateral effects including low diversity and unbalanced genres or categories, benefiting particular groups of categories. This paper proposes an approach to create recommendation lists with a calibrated balance of genres, avoiding disproportion between the user's profile interests and the recommendation list. The calibrated recommendations consider concomitantly the relevance and the divergence between the genres distributions extracted from the user's preference and the recommendation list. The main claim is that calibration can contribute positively to generate fairer recommendations. In particular, we propose a new trade-off equation, which considers the users' bias to provide a recommendation list that seeks for the users' tendencies. Moreover, we propose a conceptual framework and a decision protocol to generate more than one thousand combinations of calibrated systems in order to find the best combination. We compare our approach against state-of-the-art approaches using multiple domain datasets, which are analyzed by rank and calibration metrics. The results indicate that the trade-off, which considers the users' bias, produces positive effects on the precision and to the fairness, thus generating recommendation lists that respect the genre distribution and, through the decision protocol, we also found the best system for each dataset.

    Comment: 12 Tables and 5 figures. Submitted to a journal
    Keywords Computer Science - Information Retrieval ; Computer Science - Machine Learning
    Subject code 006
    Publishing date 2022-04-07
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Effects of aerobic, resistance, and combined training on endothelial function and arterial stiffness in older adults: study protocol for a systematic review and meta-analysis.

    da Silva, Raphael S N / da Silva, Diego S / Waclawovsky, Gustavo / Schaun, Maximiliano I

    Systematic reviews

    2022  Volume 11, Issue 1, Page(s) 171

    Abstract: Introduction: Aging is an independent risk factor for cardiovascular events. It promotes vascular dysfunction which is associated with risk factors for cardiovascular diseases (CVDs). Exercise can modulate vascular function parameters, but little is ... ...

    Abstract Introduction: Aging is an independent risk factor for cardiovascular events. It promotes vascular dysfunction which is associated with risk factors for cardiovascular diseases (CVDs). Exercise can modulate vascular function parameters, but little is known about the effects of different modalities of training (aerobic, resistance, and combined) on endothelial function and arterial stiffness in older adults.
    Methods: This systematic review study will include randomized controlled trials (RCTs) selected from the electronic databases MEDLINE (PubMed), Cochrane, LILACS, EMBASE, and Web of Science. We will follow the PRISMA guidelines and PICOS framework. Studies involving both male and female older adults (≥60 years old) with or without comorbidities undergoing aerobic, resistance, and/or combined training compared to a control group (no exercise) will be eligible. We will use the Cochrane Risk of Bias 2 (RoB 2) tool to evaluate the quality of individual studies and GRADE to assess the strength of evidence. Statistical analyses will be conducted with RStudio for Windows (v1.3.959) using R package meta.
    Discussion: A systematic review and meta-analysis involving data from studies of older adults would deepen our understanding of vascular adaptations to exercise training in this population. It could provide new insights into how health providers can improve patient management and prevention of cardiovascular events in older adults.
    Systematic review registration: PROSPERO 42021275451.
    MeSH term(s) Aged ; Cardiovascular Diseases/prevention & control ; Exercise ; Female ; Humans ; Male ; Meta-Analysis as Topic ; Middle Aged ; Randomized Controlled Trials as Topic ; Systematic Reviews as Topic ; Vascular Stiffness
    Language English
    Publishing date 2022-08-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-022-02036-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Intensifying the search-based optimization of product line architectures with crossover operators.

    da Silva, Diego Fernandes / Okada, Luiz Fernando / Assunção, Wesley K G / Colanzi, Thelma Elita

    Empirical software engineering

    2022  Volume 27, Issue 7, Page(s) 166

    Abstract: The Product Line Architecture (PLA) is a crucial artifact for the development of Software Product Lines. However, PLA is a complex artifact to be designed due to its large size and the multiple conflicting properties that need to be considered to ensure ... ...

    Abstract The Product Line Architecture (PLA) is a crucial artifact for the development of Software Product Lines. However, PLA is a complex artifact to be designed due to its large size and the multiple conflicting properties that need to be considered to ensure its quality, requiring a great effort for the architect. PLA designing has been formulated as an optimization problem aiming at improving some architectural properties in order to maximize both the feature modularization and the relational cohesion, and to minimize the class coupling. This kind of problem was successfully solved by multi-objective evolutionary algorithm. Nevertheless, most of existing approaches optimize PLA designs without applying the crossover operator, one of the fundamental genetic operators. To overcome these limitations, this paper aims to intensify the search-based PLA design optimization by presenting three crossover operators. These operators were empirically evaluated in quantitative and qualitative studies using three well-studied PLA designs. The experiments were conducted with eight experimental configurations of NSGA-II in comparison with a baseline that uses only mutation operators. Empirical results showed that there are significant differences among the use of only mutation and mutation with crossover. Also, we observed that the crossover operators contributed to generate solutions with better feature modularization. Finally, we could see that the proposed operators complement each other, since the experiment that combines at least two of the proposed operators achieved better results.
    Language English
    Publishing date 2022-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1479898-0
    ISSN 1573-7616 ; 1382-3256
    ISSN (online) 1573-7616
    ISSN 1382-3256
    DOI 10.1007/s10664-022-10198-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Differences in MCF-7 response to endocrine disruptors in waste, superficial, and treated water from Southern Brazil.

    Moreira, Marina Griebeler / Rodrigues, Gabriela Zimmermann Prado / da Silva, Diego Araújo / Bianchi, Eloisa / Gehlen, Günther / Ziulkoski, Ana Luiza

    Environmental monitoring and assessment

    2023  Volume 195, Issue 12, Page(s) 1539

    Abstract: The aim of this study was to evaluate the effect of possible endocrine disruptors in surface and wastewater using a cell proliferation assay in an estrogen-responsive cell line (MCF-7). This study was conducted in the Sinos River (Brazil). The residual ... ...

    Abstract The aim of this study was to evaluate the effect of possible endocrine disruptors in surface and wastewater using a cell proliferation assay in an estrogen-responsive cell line (MCF-7). This study was conducted in the Sinos River (Brazil). The residual water was collected from a Pilot Treatment Plant (using Typha domingensis) and surface waters of the Luis Rau stream, the Sinos River, and the Water Treatment Station (WTS). After exposures (24-120 h), a Sulforhodamine B assay was performed to determine the proliferation rate. The higher increase in proliferation rate was observed with the Luiz Rau stream and the sewage treated by macrophytes in a flotation filter. The results from WTS water remained with a proliferation rate similar to the negative control at all times, suggesting that the conventional treatment is partially effective for the withdrawal of endocrine-disrupting agents. The study demonstrated the efficiency of the MCF-7 line in assessing endocrine disruption caused by wastewater and surface water samples. Our results indicate that conventional water treatment can partially remove the polluting load of endocrine disruptors, minimizing their environmental and public health impacts. Besides, it demonstrates the need to expand sanitary services to improve the population's quality of life.
    MeSH term(s) Humans ; Endocrine Disruptors/toxicity ; Endocrine Disruptors/analysis ; Wastewater ; Environmental Monitoring/methods ; Brazil ; MCF-7 Cells ; Quality of Life ; Water Pollutants, Chemical/toxicity ; Water Pollutants, Chemical/analysis ; Waste Disposal, Fluid/methods
    Chemical Substances Endocrine Disruptors ; isononanoyl oxybenzene sulfonate (123354-92-7) ; Wastewater ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-11-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 782621-7
    ISSN 1573-2959 ; 0167-6369
    ISSN (online) 1573-2959
    ISSN 0167-6369
    DOI 10.1007/s10661-023-12109-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Saxitoxin-producing Raphidiopsis raciborskii (cyanobacteria) inhibits swimming and physiological parameters in Daphnia similis.

    Ferrão-Filho, Aloysio da S / da Silva, Diego Amparo C

    The Science of the total environment

    2019  Volume 706, Page(s) 135751

    Abstract: In this study we tested the effects of a neurotoxic strain of the cyanobacterium Raphidiopsis raciborskii (CYRF-01) on the swimming activity and physiological parameters of Daphnia similis such as movements of the antennae, thoracic limbs, post-abdominal ...

    Abstract In this study we tested the effects of a neurotoxic strain of the cyanobacterium Raphidiopsis raciborskii (CYRF-01) on the swimming activity and physiological parameters of Daphnia similis such as movements of the antennae, thoracic limbs, post-abdominal claw and heart rate. An acute assay was performed to test the effect on swimming activity, exposing newborns (<24 h) to different concentrations of live cells and observing the number of immobilized animals over a period of 48 h. For testing the effects on physiological parameters adult females (10-15 days) were exposed in a flow-through system and recorded with a digital camera. Results showed rapid effect of the strain CYRF on all parameters. Animals started to be immobilized in the first 30 min exposure and showed complete paralysis after 2 h in 500 μg L
    MeSH term(s) Animals ; Cylindrospermopsis ; Daphnia ; Saxitoxin ; Swimming
    Chemical Substances Saxitoxin (35523-89-8)
    Language English
    Publishing date 2019-11-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2019.135751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Randomized comparison of oblique and perpendicular stabilizers for minimally invasive repair of pectus excavatum.

    Tedde, Miguel L / De Carvalho, Rafael Lucas Costa / De Campos, Jose Ribas Milanez / Da Silva, Diego Arley Gomes / Okumura, Erica Mie / Guilherme, Gustavo Falavigna / Marchesi, Alana Cozzer / Petrizzo, Paulla / Souto Maior, Barbara Siqueira / Pego-Fernandes, Paulo Manuel

    Interdisciplinary cardiovascular and thoracic surgery

    2024  Volume 38, Issue 3

    Abstract: Objectives: Bar dislocation is one of the most feared complications of the minimally invasive repair of pectus excavatum.: Methods: Prospective randomized parallel-group clinical trial intending to assess whether oblique stabilizers can reduce bar ... ...

    Abstract Objectives: Bar dislocation is one of the most feared complications of the minimally invasive repair of pectus excavatum.
    Methods: Prospective randomized parallel-group clinical trial intending to assess whether oblique stabilizers can reduce bar displacement in comparison with regular stabilizers used in minimally invasive repair of pectus excavatum. Additionally, we evaluated pain, quality of life and other postoperative complications. Participants were randomly assigned to surgery with perpendicular (n = 16) or oblique stabilizers (n = 14) between October 2017 and September 2018 and followed for 3 years. Bar displacements were evaluated with the bar displacement index. Pain scores were evaluated through visual analogue scale and quality of life through the Pectus Excavatum Evaluation Questionnaire.
    Results: Control group average displacement index was 17.7 (±26.7) and intervention group average displacement index was 8.2 (±10.9). There was 1 reoperation in each group that required correction with 2 bars. Bar displacement was similar among groups (P = 0.12). No other complications were recorded. There was no statistically significant difference on pain score. There was a significant difference between pre- and postoperative composite scores of the participants' body image domain and psycho-social aspects in both groups. The difference between the pre- and postoperative participants' perception of physical difficulties was greater and statistically significant in the intervention group.
    Conclusions: There was no statistical difference in the use of perpendicular or oblique stabilizers, but the availability of different models of stabilizers during the study suggested that this can be advantageous. The trial is registered at ClinicalTrials.gov, number NCT03087734.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ISSN 2753-670X
    ISSN (online) 2753-670X
    DOI 10.1093/icvts/ivae040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Assessing physiological responses and oxidative stress effects in Rhamdia voulezi exposed to high temperatures.

    da Silva, Diego Ortiz / Ratko, Jonathan / Côrrea, Ana Paula Nascimento / da Silva, Niumaique Gonçalves / Pereira, Diego Mauro Carneiro / Schleger, Ieda Cristina / Neundorf, Ananda Karla Alvez / de Souza, Maria Rosa Dmengeon Pedreiro / Herrerias, Tatiana / Donatti, Lucélia

    Fish physiology and biochemistry

    2024  Volume 50, Issue 2, Page(s) 617–633

    Abstract: Exposure to high temperatures induces changes in fish respiration, resulting in an increased production of reactive oxygen species. This, in turn, affects the enzymatic and non-enzymatic components of antioxidant defenses, which are essential for ... ...

    Abstract Exposure to high temperatures induces changes in fish respiration, resulting in an increased production of reactive oxygen species. This, in turn, affects the enzymatic and non-enzymatic components of antioxidant defenses, which are essential for mitigating cellular stress. Rhamdia voulezi, an economically important fish species endemic to Brazil's Iguaçu River, served as the subject of our study. Our goal was to assess enzymatic antioxidant biomarkers (superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase, glutathione reductase, glucose-6-phosphate dehydrogenase), non-protein thiol levels (reduced glutathione), and markers of oxidative damage (lipoperoxidation and carbonylation) in the liver, gills, and kidneys of R. voulezi after acute exposure to high temperatures (31°C) for 2, 6, 12, 24, and 96 h. Control groups were maintained at 21°C. Our findings revealed that the liver exhibited increased superoxide dismutase levels up to 12 h and elevated glutathione S-transferase levels at 12 and 96 h at 31°C. In the gills, superoxide dismutase levels increased up to 24 h, along with increased lipoperoxidation at 2, 6, 12, and 96 h of exposure to high temperatures. The kidneys responded to heat stress at 12 h, with an increase in superoxide dismutase and catalase activity, and lipid peroxidation was observed at 2 and 6 h at 31°C. The three tissues evaluated responded differently to heat stress, with the liver demonstrating greater physiological adjustment to high temperatures. The intricate interplay of various antioxidant defense biomarkers and oxidative damage suggests the presence of oxidative stress in R. voulezi when exposed to high temperatures.
    MeSH term(s) Animals ; Antioxidants/metabolism ; Catalase/metabolism ; Temperature ; Oxidative Stress/physiology ; Glutathione/metabolism ; Catfishes/metabolism ; Superoxide Dismutase/metabolism ; Biomarkers/metabolism ; Glutathione Peroxidase/metabolism ; Glutathione Transferase/metabolism ; Gills/metabolism ; Lipid Peroxidation
    Chemical Substances Antioxidants ; Catalase (EC 1.11.1.6) ; Glutathione (GAN16C9B8O) ; Superoxide Dismutase (EC 1.15.1.1) ; Biomarkers ; Glutathione Peroxidase (EC 1.11.1.9) ; Glutathione Transferase (EC 2.5.1.18)
    Language English
    Publishing date 2024-01-04
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 292907-7
    ISSN 1573-5168 ; 0920-1742
    ISSN (online) 1573-5168
    ISSN 0920-1742
    DOI 10.1007/s10695-023-01294-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Application of Artificial Intelligence to Automate the Reconstruction of Muscle Cross-Sectional Area Obtained by Ultrasound.

    da Silva, Deivid Gomes / da Silva, Diego Gomes / Angleri, Vitor / Scarpelli, Maíra Camargo / Bergamasco, João Guilherme Almeida / Nóbrega, Sanmy Rocha / Damas, Felipe / Chaves, Talisson Santos / de Arruda Camargo, Heloísa / Ugrinowitsch, Carlos / Libardi, Cleiton Augusto

    Medicine and science in sports and exercise

    2024  

    Abstract: Purpose: Manual reconstruction (MR) of the vastus lateralis (VL) muscle cross sectional area (CSA) from sequential ultrasound (US) images is accessible, reproducible and has concurrent validity with magnetic resonance imaging. However, this technique ... ...

    Abstract Purpose: Manual reconstruction (MR) of the vastus lateralis (VL) muscle cross sectional area (CSA) from sequential ultrasound (US) images is accessible, reproducible and has concurrent validity with magnetic resonance imaging. However, this technique requires numerous controls and procedures during image acquisition and reconstruction, making it laborious and time-consuming. The aim of this study was to determine the concurrent validity of VL CSA assessments between MR and computer vision-based automatic reconstruction (AR) of CSA from sequential images of the VL obtained by US.
    Methods: The images from each sequence were manually rotated to align the fascia between images and thus visualize the VL CSA. For the AR, an artificial neural network model was utilized to segment areas of interest in the image, such as skin, fascia, deep aponeurosis, and femur. This segmentation was crucial to impose necessary constraints for the main assembly phase. At this stage, an image registration application, combined with differential evolution, was employed to achieve appropriate adjustments between the images. Next, the VL CSA obtained from the MR (n = 488) and AR (n = 488) techniques were used to determine their concurrent validity.
    Results: Our findings demonstrated a low coefficient of variation (CV) (1.51%) for AR compared to MR. The Bland-Altman plot showed low bias and close limits of agreement (+1.18 cm2, -1.19 cm2), containing more than 95% of the data points.
    Conclusions: The AR technique is valid compared to MR when measuring VL CSA in a heterogeneous sample.
    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603994-7
    ISSN 1530-0315 ; 0195-9131 ; 0025-7990
    ISSN (online) 1530-0315
    ISSN 0195-9131 ; 0025-7990
    DOI 10.1249/MSS.0000000000003456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diacetylcurcumin: a novel strategy against

    Souza, Vanessa de / Polaquini, Carlos Roberto / de Moraes, Graciele Ribeiro / Oliveira Braga, Arthur Rodrigues / da Silva, Priscila Vieira / da Silva, Diego Romário / Ribeiro Lima, Francisco Ricardo / Regasini, Luís Octávio / Cássia Orlandi Sardi, Janaina de

    Future microbiology

    2024  

    Abstract: Aim: ...

    Abstract Aim:
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254620-0
    ISSN 1746-0921 ; 1746-0913
    ISSN (online) 1746-0921
    ISSN 1746-0913
    DOI 10.2217/fmb-2023-0235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dermatomyositis: A diagnostic dilemma.

    Da Silva, Diego M / Patel, Basil / Werth, Victoria P

    Journal of the American Academy of Dermatology

    2018  Volume 79, Issue 2, Page(s) 371–373

    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Biopsy ; Dermatomyositis/diagnosis ; Dermatomyositis/pathology ; Diagnosis, Differential ; Diagnostic Errors ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Language English
    Publishing date 2018-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2017.12.074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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