LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Idiopathic Nephrotic Syndrome in Pediatrics: An Up-to-date.

    da Silva Filha, Roberta / Burini, Kassia / Pires, Laura Gregório / Brant Pinheiro, Sérgio Veloso / Simões E Silva, Ana Cristina

    Current pediatric reviews

    2022  Volume 18, Issue 4, Page(s) 251–264

    Abstract: Background: Idiopathic or Primary Nephrotic Syndrome (INS) is a common glomerular disease in pediatric population, characterized by proteinuria, edema and hypoalbuminemia with variable findings in renal histopathology.: Objective: This review aims to ...

    Abstract Background: Idiopathic or Primary Nephrotic Syndrome (INS) is a common glomerular disease in pediatric population, characterized by proteinuria, edema and hypoalbuminemia with variable findings in renal histopathology.
    Objective: This review aims to summarize current data on the etiopathogenesis diagnosis, protocols of treatment and potential therapeutic advances in INS.
    Methods: This narrative review searched for articles on histopathology, physiopathology, genetic causes, diagnosis and treatment of INS in pediatric patients. The databases evaluated were PubMed and Scopus.
    Results: INS is caused by an alteration in the permeability of the glomerular filtration barrier with unknown etiology. There are several gaps in the etiopathogenesis, response to treatment and clinical course of INS that justify further investigation. Novel advances include the recent understanding of the role of podocytes in INS and the identification of genes associated with the disease. The role of immune system cells and molecules has also been investigated. The diagnosis relies on clinical findings, laboratory exams and renal histology for selected cases. The treatment is primarily based on steroids administration. In case of failure, other medications should be tried. Recent studies have also searched for novel biomarkers for diagnosis and alternative therapeutic approaches.
    Conclusion: The therapeutic response to corticosteroids still remains the main predictive factor for the prognosis of the disease. Genetic and pharmacogenomics tools may allow the identification of cases not responsive to immunosuppressive medications.
    MeSH term(s) Adrenal Cortex Hormones ; Child ; Glomerulosclerosis, Focal Segmental ; Humans ; Kidney ; Nephrotic Syndrome
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2022-03-14
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ISSN 1875-6336
    ISSN (online) 1875-6336
    DOI 10.2174/1573396318666220314142713
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Nephrotic Syndrome and Renin-angiotensin System: Pathophysiological Role and Therapeutic Potential.

    Dos Anjos, Alessandra Aguiar / de Paiva, Isadora Tucci / Simões Lima, Giovanna Letícia / da Silva Filha, Roberta / Fróes, Brunna Pinto E / Brant Pinheiro, Sérgio Veloso / Silva, Ana Cristina Simões E

    Current molecular pharmacology

    2022  Volume 16, Issue 4, Page(s) 465–474

    Abstract: Idiopathic Nephrotic Syndrome (INS) is the most frequent etiology of glomerulopathy in pediatric patients and one of the most common causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) in this population. In this review, we aimed to ...

    Abstract Idiopathic Nephrotic Syndrome (INS) is the most frequent etiology of glomerulopathy in pediatric patients and one of the most common causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) in this population. In this review, we aimed to summarize evidence on the pathophysiological role and therapeutic potential of the Renin-Angiotensin System (RAS) molecules for the control of proteinuria and for delaying the onset of CKD in patients with INS. This is a narrative review in which the databases PubMed, Web of Science, and Sci- ELO were searched for articles about INS and RAS. We selected articles that evaluated the pathophysiological role of RAS and the effects of the alternative RAS axis as a potential therapy for INS. Several studies using rodent models of nephropathies showed that the treatment with activators of the Angiotensin-Converting Enzyme 2 (ACE2) and with Mas receptor agonists reduces proteinuria and improves kidney tissue damage. Another recent paper showed that the reduction of urinary ACE2 levels in children with INS correlates with proteinuria and higher concentrations of inflammatory cytokines, although data with pediatric patients are still limited. The molecules of the alternative RAS axis comprise a wide spectrum, not yet fully explored, of potential pharmacological targets for kidney diseases. The effects of ACE2 activators and receptor Mas agonists show promising results that can be useful for nephropathies including INS.
    MeSH term(s) Humans ; Angiotensin-Converting Enzyme 2 ; Nephrotic Syndrome/drug therapy ; Proteinuria ; Renal Insufficiency, Chronic/drug therapy ; Renin-Angiotensin System/physiology
    Chemical Substances Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Language English
    Publishing date 2022-06-20
    Publishing country United Arab Emirates
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1874-4702
    ISSN (online) 1874-4702
    DOI 10.2174/1874467215666220616152312
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Costus spiralis extract restores kidney function in cisplatin-induced nephrotoxicity model: Ethnopharmacological use, chemical and toxicological investigation

    Amorim, Juliana Mendes / Ribeiro de Souza, Larissa Camila / Lemos de Souza, Rebecca Almeida / da Silva Filha, Roberta / de Oliveira Silva, Juliana / de Almeida Araújo, Stanley / Tagliti, Carlos Alberto / Simões e Silva, Ana Cristina / Castilho, Rachel Oliveira

    Journal of ethnopharmacology. 2022 June 22,

    2022  

    Abstract: Costus spiralis (Jacq.). Roscoe (Costaceae) is traditionally used in Brazil for the treatment of kidney diseases such as pyelonephritis, urethra inflammation, kidney stones, and inflammatory conditions. There are reports of its use by Brazilian Indians ... ...

    Abstract Costus spiralis (Jacq.). Roscoe (Costaceae) is traditionally used in Brazil for the treatment of kidney diseases such as pyelonephritis, urethra inflammation, kidney stones, and inflammatory conditions. There are reports of its use by Brazilian Indians since the 17th century when it was known as “pacocatinga.” Currently, the use of the Costus species in Brazil is widespread, which was evidenced by the inclusion of the genus in the Brazilian National List of Medicinal Plants of Interest to the Unified Health System (RENISUS). This study aimed to confirm the ethnopharmacological use of Costus spiralis in the treatment of kidney diseases, toxicity study using animal models, and the phytochemistry of the species. The chemical profile of Costus spiralis leaves extract (CSLE) was obtained for the hydroethanolic extract by ultra-performance liquid chromatography coupled to a mass spectrometer and ultraviolet detector with diode array (UPLC-UV/DAD-ESI-MS). The acute oral toxicity of the extract was predicted using the neutral red uptake cytotoxicity assay. Wistar rats were used in a model in vivo for confirmation of acute oral toxicity (2000 mg/kg p. o. for 14 days.) and determination of the effect on a cisplatin-induced nephrotoxicity model. The analysis by UPLC-UV/DAD-ESI-MS showed that the chemical composition of the extract is mostly di-glycosylated flavones of apigenin. In the extract were identified the flavones vicenin II and schaftoside. The quantification of total flavonoids by spectrometry showed 0.880%. CSLE proved to be safe for acute oral administration (2000 mg/kg) with an IC₅₀ value of 222.9 μg/mL and predicted oral toxic dose of 523.82 μg/mL in a neutral red uptake cytotoxicity assay. The absence of death allows the classification of the extract in class 5 according to OECD 423 guidelines and therefore it can be considered as a high acute safety product, which is highly relevant, considering the wide popular use of the species. In the cisplatin-induced nephrotoxicity model, C. spiralis extract (5, 15, and 30 mg/kg) significantly improved renal function, reversing almost completely the effects on plasma creatinine levels and creatinine clearance (p < 0.001). This study demonstrates that oral administration of Costus spiralis extract leaves is safe and effective in restoring the renal function in rats in a cisplatin-induced nephrotoxicity. It is suggested that the observed activity is related to the flavonoids present. This hypothesis should be confirmed, and the participation of other secondary metabolites should be investigated in the future.
    Keywords Costus ; acute oral toxicity ; apigenin ; chemical composition ; creatinine ; death ; diodes ; inflammation ; kidneys ; nephrotoxicity ; oral administration ; pyelonephritis ; renal function ; secondary metabolites ; spectrometers ; spectroscopy ; traditional medicine ; ultra-performance liquid chromatography ; urethra ; Brazil
    Language English
    Dates of publication 2022-0622
    Publishing place Elsevier B.V.
    Document type Article
    Note Pre-press version
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2022.115510
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 90/710: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Costus spiralis extract restores kidney function in cisplatin-induced nephrotoxicity model: Ethnopharmacological use, chemical and toxicological investigation.

    Amorim, Juliana Mendes / Ribeiro de Souza, Larissa Camila / Lemos de Souza, Rebecca Almeida / da Silva Filha, Roberta / de Oliveira Silva, Juliana / de Almeida Araújo, Stanley / Tagliti, Carlos Alberto / Simões E Silva, Ana Cristina / Castilho, Rachel Oliveira

    Journal of ethnopharmacology

    2022  Volume 299, Page(s) 115510

    Abstract: Ethnopharmacological relevance: Costus spiralis (Jacq.). Roscoe (Costaceae) is traditionally used in Brazil for the treatment of kidney diseases such as pyelonephritis, urethra inflammation, kidney stones, and inflammatory conditions. There are reports ... ...

    Abstract Ethnopharmacological relevance: Costus spiralis (Jacq.). Roscoe (Costaceae) is traditionally used in Brazil for the treatment of kidney diseases such as pyelonephritis, urethra inflammation, kidney stones, and inflammatory conditions. There are reports of its use by Brazilian Indians since the 17th century when it was known as "pacocatinga." Currently, the use of the Costus species in Brazil is widespread, which was evidenced by the inclusion of the genus in the Brazilian National List of Medicinal Plants of Interest to the Unified Health System (RENISUS).
    Aim of the study: This study aimed to confirm the ethnopharmacological use of Costus spiralis in the treatment of kidney diseases, toxicity study using animal models, and the phytochemistry of the species.
    Materials and methods: The chemical profile of Costus spiralis leaves extract (CSLE) was obtained for the hydroethanolic extract by ultra-performance liquid chromatography coupled to a mass spectrometer and ultraviolet detector with diode array (UPLC-UV/DAD-ESI-MS). The acute oral toxicity of the extract was predicted using the neutral red uptake cytotoxicity assay. Wistar rats were used in a model in vivo for confirmation of acute oral toxicity (2000 mg/kg p.o. for 14 days.) and determination of the effect on a cisplatin-induced nephrotoxicity model.
    Results: The analysis by UPLC-UV/DAD-ESI-MS showed that the chemical composition of the extract is mostly di-glycosylated flavones of apigenin. In the extract were identified the flavones vicenin II and schaftoside. The quantification of total flavonoids by spectrometry showed 0.880%. CSLE proved to be safe for acute oral administration (2000 mg/kg) with an IC
    Conclusions: This study demonstrates that oral administration of Costus spiralis extract leaves is safe and effective in restoring the renal function in rats in a cisplatin-induced nephrotoxicity. It is suggested that the observed activity is related to the flavonoids present. This hypothesis should be confirmed, and the participation of other secondary metabolites should be investigated in the future.
    MeSH term(s) Animals ; Apigenin ; Cisplatin/toxicity ; Costus/chemistry ; Creatinine ; Flavones/analysis ; Flavonoids/analysis ; Humans ; Kidney ; Neutral Red/analysis ; Plant Extracts/analysis ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plant Leaves/chemistry ; Rats ; Rats, Wistar
    Chemical Substances Flavones ; Flavonoids ; Plant Extracts ; Neutral Red (261QK3SSBH) ; Apigenin (7V515PI7F6) ; Creatinine (AYI8EX34EU) ; Cisplatin (Q20Q21Q62J)
    Language English
    Publishing date 2022-06-27
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2022.115510
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1494: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Beneficial Effects of the Angiotensin-Converting Enzyme 2 Activator Dize in Renovascular Hypertension.

    Kangussu, Lucas Miranda / de Almeida, Tatiane Cristine S / Prestes, Thiago Ruiz R / de Andrade De Maria, Marilda Luz / da Silva Filha, Roberta / Vieira, Maria Aparecida Ribeiro / Silva, Ana Cristina Simões E / Ferreira, Anderson José

    Protein and peptide letters

    2019  Volume 26, Issue 7, Page(s) 523–531

    Abstract: Background: Angiotensin Converting Enzyme (ACE) 2 is an important modulator of the Renin Angiotensin System (RAS) and the RAS plays a central role in renovascular hypertension. Very few studies investigated the role of components of the ... ...

    Abstract Background: Angiotensin Converting Enzyme (ACE) 2 is an important modulator of the Renin Angiotensin System (RAS) and the RAS plays a central role in renovascular hypertension. Very few studies investigated the role of components of the counterregulatory RAS axis (ACE2, Ang-(1-7) and Mas receptor) in renovascular hypertension and the results are controversial.
    Objective: The aim of this study was to investigate the effects of Diminazene Aceturate (DIZE) administration on renal function and renal inflammation parameters in 2K1C hypertensive rats.
    Methods: Male Wistar rats were divided into three experimental groups: sham-operated animals, 2K1C+saline and 2K1C+DIZE orally (1 mg/kg/day). At the end of the 30 days of treatment, renal function was analyzed and kidneys from all the groups were collected and processed separately for measurement of N-acetyl-beta-D-glucosaminidase (NAG) and Myeloperoxidase (MPO) activities, cytokines, chemokines and nitric oxide levels.
    Results: Oral DIZE administration for 4 weeks in hypertensive rats attenuated renal dysfunction and reduced the levels of MPO and NAG, cytokines and chemokines (IL1β, IL-6, TNF-α and MCP-1) and increased urinary nitrate/nitrite levels in 2K1C hypertensive rats.
    Conclusion: Our findings showed that ACE2 activation may effectively improve renal alterations and inflammation induced by renovascular hypertension.
    MeSH term(s) Acetylglucosaminidase/metabolism ; Angiotensin I/metabolism ; Animals ; Cytokines/metabolism ; Diminazene/analogs & derivatives ; Diminazene/pharmacology ; Diminazene/therapeutic use ; Enzyme Activators/pharmacology ; Enzyme Activators/therapeutic use ; Hypertension, Renovascular/drug therapy ; Hypertension, Renovascular/metabolism ; Hypertension, Renovascular/physiopathology ; Inflammation/drug therapy ; Inflammation/metabolism ; Kidney/drug effects ; Kidney/physiopathology ; Male ; Nitric Oxide/metabolism ; Peptide Fragments/metabolism ; Peptidyl-Dipeptidase A/metabolism ; Peroxidase/metabolism ; Rats, Wistar ; Renin-Angiotensin System/drug effects
    Chemical Substances Cytokines ; Enzyme Activators ; Peptide Fragments ; Nitric Oxide (31C4KY9ESH) ; Angiotensin I (9041-90-1) ; Peroxidase (EC 1.11.1.7) ; Acetylglucosaminidase (EC 3.2.1.52) ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; angiotensin converting enzyme 2 (EC 3.4.17.-) ; angiotensin I (1-7) (IJ3FUK8MOF) ; diminazene aceturate (JI8SAD85NO) ; Diminazene (Y5G36EEA5Z)
    Language English
    Publishing date 2019-08-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1280776-x
    ISSN 1875-5305 ; 0929-8665
    ISSN (online) 1875-5305
    ISSN 0929-8665
    DOI 10.2174/0929866526666190405123422
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4452: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: ACE2 activator diminazene aceturate exerts renoprotective effects in gentamicin-induced acute renal injury in rats.

    Silva de Almeida, Tatiane Cristine / Lanza, Katharina / da Silva Filha, Roberta / C Campos, Leda Maria de Castro / Fonseca, Esdras G / Chagas, Mariana W / Rocha, Natalia Pessoa / de Sá, Marcos Augusto / Vieira, Maria Aparecida Ribeiro / Caliari, Marcelo Vidigal / Kangussu, Lucas M / Ferreira, Anderson José / Simões E Silva, Ana Cristina

    Clinical science (London, England : 1979)

    2020  Volume 134, Issue 23, Page(s) 3093–3106

    Abstract: Acute Kidney Injury (AKI) comprises a rapidly developed renal failure and is associated with high mortality rates. The Renin-Angiotensin System (RAS) plays a pivotal role in AKI, as the over-active RAS axis exerts major deleterious effects in disease ... ...

    Abstract Acute Kidney Injury (AKI) comprises a rapidly developed renal failure and is associated with high mortality rates. The Renin-Angiotensin System (RAS) plays a pivotal role in AKI, as the over-active RAS axis exerts major deleterious effects in disease progression. In this sense, the conversion of Angiotensin II (Ang II) into Angiotensin-(1-7) (Ang-(1-7)) by the Angiotensin-converting enzyme 2 (ACE2) is of utmost importance to prevent worse clinical outcomes. Previous studies reported the beneficial effects of oral diminazene aceturate (DIZE) administration, an ACE2 activator, in renal diseases models. In the present study, we aimed to evaluate the therapeutic effects of DIZE administration in experimental AKI induced by gentamicin (GM) in rats. Our findings showed that treatment with DIZE improved renal function and tissue damage by increasing Ang-(1-7) and ACE2 activity, and reducing TNF-α. These results corroborate with a raising potential of ACE2 activation as a strategy for treating AKI.
    MeSH term(s) Acute Kidney Injury/drug therapy ; Acute Kidney Injury/enzymology ; Acute Kidney Injury/physiopathology ; Acute Kidney Injury/urine ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Biomarkers/metabolism ; Body Weight/drug effects ; Cytokines/metabolism ; Diminazene/analogs & derivatives ; Diminazene/pharmacology ; Diminazene/therapeutic use ; Enzyme Activators/pharmacology ; Gentamicins/adverse effects ; Inflammation/pathology ; Kidney/drug effects ; Kidney/pathology ; Kidney/physiopathology ; Male ; Protective Agents/pharmacology ; Protective Agents/therapeutic use ; Rats, Wistar ; Renin-Angiotensin System
    Chemical Substances Biomarkers ; Cytokines ; Enzyme Activators ; Gentamicins ; Protective Agents ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) ; diminazene aceturate (JI8SAD85NO) ; Diminazene (Y5G36EEA5Z)
    Language English
    Publishing date 2020-11-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 206835-7
    ISSN 1470-8736 ; 0301-0538 ; 0009-0360 ; 0143-5221
    ISSN (online) 1470-8736
    ISSN 0301-0538 ; 0009-0360 ; 0143-5221
    DOI 10.1042/CS20201022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.220: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: The Curcumin Supplementation with Piperine Can Influence the Acute Elevation of Exercise-Induced Cytokines: Double-Blind Crossover Study.

    Miranda-Castro, Stéfani / Aidar, Felipe J / de Moura, Samara Silva / Marcucci-Barbosa, Lucas / Lobo, Lázaro Fernandes / de Assis Dias Martins-Júnior, Francisco / da Silva Filha, Roberta / Vaz de Castro, Pedro Alves Soares / Simões E Silva, Ana Cristina / da Glória de Souza, Danielle / da Silva, Siomara Aparecida / de Castro Pinto, Kelerson Mauro / de Paula Costa, Guilherme / Silva, Ana Filipa / Clemente, Filipe Manuel / Pereira, William Valadares Campos / Nunes-Silva, Albená

    Biology

    2022  Volume 11, Issue 4

    Abstract: Background: to evaluate the effects of one week of supplementation with curcumin combined with piperine on physical performance, immune system cell counts, muscle damage, and plasma levels of inflammatory markers after a treadmill running training ... ...

    Abstract Background: to evaluate the effects of one week of supplementation with curcumin combined with piperine on physical performance, immune system cell counts, muscle damage, and plasma levels of inflammatory markers after a treadmill running training session.
    Methods: This study is a double-blind, crossover-balanced clinical trial with a three-week intervention. Sixteen male runners with a mean age of 36 ± 9 years and VO2 max of 60.6 ± 9.03 mL.kg
    Results: curcumin and piperine supplementation could not change the physical performance, immune cell counts, and muscle damage; however, the aerobic fatiguing exercise protocol inhibited the elevation of the plasmatic levels of some cytokines. The running exercise protocol could elevate the circulating levels of IL-2 (from 49.7 to 59.3 pg/mL), TNF-α (from 48.5 to 51.5 pg/mL), INF (from 128.8 to 165.0 pg/mL), IL-6 (from 63.1 to 77.3 pg/mL), and IL-10 (from 48.9 to 59.6 pg/mL) 1 h after the end of the running protocol. However, the curcumin and piperine supplementation could inhibit this elevation.
    Conclusions: curcumin and piperine supplementation had no effect on physical performance, immune cell counts, or muscle damage; however, the supplementation could modulate the kinetics of IL-2, TNF-α, INF, IL-6, and IL-10 1 h after the end of exercise.
    Language English
    Publishing date 2022-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661517-4
    ISSN 2079-7737
    ISSN 2079-7737
    DOI 10.3390/biology11040573
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top