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  1. Article ; Online: High prevalence of potential psychotropic drugs interactions among Brazilian dental patients.

    Cruz, Alex Junio Silva / Martins, Maria Auxiliadora Parreiras / de Aguilar, Diego Rodrigues / Santos, Jacqueline Silva / Sohn, Woosung / de Castilho, Lia Silva / Abreu, Mauro Henrique Nogueira Guimarães

    Oral diseases

    2023  Volume 30, Issue 3, Page(s) 1606–1613

    Abstract: Objective: To determine the prevalence of potential drug-drug interactions involving psychotropics prescribed by dentists, and dispensed by the public healthcare system, as well as to describe the severity and level of evidence of those interactions in ... ...

    Abstract Objective: To determine the prevalence of potential drug-drug interactions involving psychotropics prescribed by dentists, and dispensed by the public healthcare system, as well as to describe the severity and level of evidence of those interactions in the state of Minas Gerais, Brazil.
    Materials and methods: We conducted data analysis from pharmaceutical claims in which dental patients received systemic psychotropics in 2017. Data from the Pharmaceutical Management System provided the drug dispensing history of the patients, allowing the identification of those on concomitant medication use. The outcome was the occurrence of potential drug-drug interactions, which were detected according to IBM Micromedex®. Independent variables were the patient's sex, age, and the number of drugs used. Descriptive statistics was performed using SPSS v. 26.
    Results: Overall, 1480 individuals were prescribed psychotropic drugs. The prevalence of potential drug-drug interactions was 24.8% (n = 366). The total of 648 interactions was observed and, most of which were of major severity (n = 438, 67.6%). Most interactions occurred in female individuals (n = 235; 64.2%), with 46.0 (±17.3) years-old, concurrently taking 3.7 (±1.9) drugs.
    Conclusion: A substantial proportion of dental patients presented potential drug-drug interactions, mostly of major severity, which might be life-threatening.
    MeSH term(s) Humans ; Psychotropic Drugs/therapeutic use ; Brazil/epidemiology ; Drug Interactions ; Female ; Male ; Middle Aged ; Adult ; Prevalence ; Aged ; Young Adult ; Adolescent ; Dental Care/statistics & numerical data
    Chemical Substances Psychotropic Drugs
    Language English
    Publishing date 2023-03-13
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Association between Stress at Work and Temporomandibular Disorders: A Systematic Review.

    Aranha, Ricardo Luiz de Barreto / Martins, Renata de Castro / de Aguilar, Diego Rodrigues / Moreno-Drada, Johana Alejandra / Sohn, Woosung / Martins, Carolina de Castro / de Abreu, Mauro Henrique Nogueira Guimarães

    BioMed research international

    2021  Volume 2021, Page(s) 2055513

    Abstract: Temporomandibular disorders (TMD) have been traditionally associated with psychosocial factors; however, occupational stress as a factor related to TMD has not been adequately assessed in the literature. The aim was to investigate the association between ...

    Abstract Temporomandibular disorders (TMD) have been traditionally associated with psychosocial factors; however, occupational stress as a factor related to TMD has not been adequately assessed in the literature. The aim was to investigate the association between stress at work and TMD on adult paid workers. An electronic search included PubMed, Scopus, Web of Science, Embase, and LILACS databases. Manual searches in the included articles' reference and gray literature were performed. There were no restrictions regarding language or publication period. The inclusion criteria comprised observational studies with paid workers of any category, of both sexes, above 18 years old, assessing occupational stress/stress or distress and TMD as diagnosis or isolated signs and symptoms. Methodological quality was evaluated using Joanna Briggs tools. We narratively assessed the evidence using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. We collected 12 studies. 50% reported a positive association between stress and TMD diagnostic across various job categories. On the other hand, TMJ sounds (a TMD sign) and work stress were associated only in a musicians' population. However, the shortage of eligible articles and the methodological limitations provided a very low certainty of the evidence; only 4 of the studies used validated tools for both stress and TMD (2 reporting positive association). The association between stress and TMD is inconclusive by the available data. In the future, we expect more robust epidemiologic studies addressing these relevant aspects.
    MeSH term(s) Humans ; Occupational Stress/complications ; Publications ; Temporomandibular Joint Disorders/psychology
    Language English
    Publishing date 2021-05-15
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2021/2055513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Biosafety in Dental Health Care During the COVID-19 Pandemic: A Longitudinal Study.

    Miguita, Lucyene / Martins-Chaves, Roberta Rayra / Geddes, Victor Emmanuel Viana / Mendes, Suellen da Rocha / Costa, Sara Ferreira Dos Santos / Fonseca, Paula Luize Camargos / Menezes, Diego / de Souza, Rafael Marques / Queiroz, Daniel Costa / Alves, Hugo José / de Freitas, Raphaela Alvarenga Braga / Cruz, Aline Fernanda / Moreira, Rennan Garcias / Moreira, Filipe Romero Rebello / Bemquerer, Larissa Marques / de Aguilar, Diego Rodrigues / de Souza E Silva, Maria Elisa / Sampaio, Aline Araújo / Jardilino, Francisca Daniele Moreira /
    de Souza, Leandro Napier / da Silva, Tarcilia Aparecida / Gomes, Carolina Cavaliéri / de Abreu, Mauro Henrique Nogueira Guimarães / de Aguiar, Renato Santana / de Souza, Renan Pedra / Gomez, Ricardo Santiago

    Frontiers in oral health

    2022  Volume 3, Page(s) 871107

    Abstract: Background: The coronavirus disease 2019 (COVID-19) pandemic had quite an impact on dental health care. Concerns about the risk of SARS-CoV-2 transmission through contaminant fluids and droplet formation during several dental procedures highly impacted ... ...

    Abstract Background: The coronavirus disease 2019 (COVID-19) pandemic had quite an impact on dental health care. Concerns about the risk of SARS-CoV-2 transmission through contaminant fluids and droplet formation during several dental procedures highly impacted dental health care, drastically reducing the number of dental practices worldwide. To monitor SARS-CoV-2 contamination in dental clinics, a longitudinal study was carried out during the return of dental practice at university.
    Methods: Dental health care professionals [(DHCPs); teachers, undergraduate dental students, and dental assistants] and patients were screened for SARS-CoV-2 RNA in a dental school clinic environment from 11
    Results: We found a low number of dental staff (5.8%), patients (0.9%), and environment sites (0.8%) positive for SARS-CoV-2. Most positive cases had asymptomatic to mild symptoms, and two asymptomatic DHCPs presented prolonged infection. In the first week after previous exposure to COVID-19, 16.2% of DHCPs had IgM or IgG antibodies against SARS-CoV-2, and 1/3 of them had undetected antibodies in the last weeks. The variant zeta (P.2) could be detected. No cross-infection was observed between participants.
    Conclusion: Our study suggests that dental practice can be safely executed when adequate control measures and biosafety protocols are applied. DHCP and patient testing, patient telemonitoring, proper use of personal protection equipment, and sanitization of surfaces are essential to avoid SARS-CoV-2 cross-infection in dental practice.
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-4842
    ISSN (online) 2673-4842
    DOI 10.3389/froh.2022.871107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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