Article ; Online: Platelet reactivity in overweight and obese patients undergoing cardiac surgery.
2018 Volume 30, Issue 5, Page(s) 608–614
Abstract: Body mass index (BMI) and specifically overweight and obesity have been associated with an increased platelet reactivity in different series of patients. This information is derived by different laboratory platelet function tests (PFTs) like mean ... ...
Abstract | Body mass index (BMI) and specifically overweight and obesity have been associated with an increased platelet reactivity in different series of patients. This information is derived by different laboratory platelet function tests (PFTs) like mean platelet volume (MPV), platelet microparticles, thromboxane B2 metabolites, and others. Point-of-care PFT, which are often used in cardiac surgery, are rarely addressed. The present study aims to verify platelet reactivity using multiple-electrode aggregometry (MEA) as a function of BMI in cardiac surgery patients. One-hundred ninety-eight cardiac surgery patients free from the effects of drugs acting on the P2Y |
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MeSH term(s) | Aged ; Biomarkers ; Blood Coagulation ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Cardiac Surgical Procedures ; Cohort Studies ; Comorbidity ; Female ; Heart Diseases/blood ; Heart Diseases/complications ; Heart Diseases/surgery ; Humans ; Male ; Middle Aged ; Obesity/blood ; Obesity/complications ; Overweight/blood ; Overweight/complications ; Platelet Activation/drug effects ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Function Tests |
Chemical Substances | Biomarkers ; Platelet Aggregation Inhibitors |
Language | English |
Publishing date | 2018-07-09 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 1034283-7 |
ISSN | 1369-1635 ; 0953-7104 |
ISSN (online) | 1369-1635 |
ISSN | 0953-7104 |
DOI | 10.1080/09537104.2018.1492108 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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