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  1. Article ; Online: Platelet reactivity in overweight and obese patients undergoing cardiac surgery.

    Ranucci, Marco / Aloisio, Tommaso / Dedda, Umberto Di / La Rovere, Maria Teresa / De Arroyabe, Blanca Martinez Lopez / Baryshnikova, Ekaterina

    Platelets

    2018  Volume 30, Issue 5, Page(s) 608–614

    Abstract: Body mass index (BMI) and specifically overweight and obesity have been associated with an increased platelet reactivity in different series of patients. This information is derived by different laboratory platelet function tests (PFTs) like mean ... ...

    Abstract Body mass index (BMI) and specifically overweight and obesity have been associated with an increased platelet reactivity in different series of patients. This information is derived by different laboratory platelet function tests (PFTs) like mean platelet volume (MPV), platelet microparticles, thromboxane B2 metabolites, and others. Point-of-care PFT, which are often used in cardiac surgery, are rarely addressed. The present study aims to verify platelet reactivity using multiple-electrode aggregometry (MEA) as a function of BMI in cardiac surgery patients. One-hundred ninety-eight cardiac surgery patients free from the effects of drugs acting on the P2Y
    MeSH term(s) Aged ; Biomarkers ; Blood Coagulation ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Cardiac Surgical Procedures ; Cohort Studies ; Comorbidity ; Female ; Heart Diseases/blood ; Heart Diseases/complications ; Heart Diseases/surgery ; Humans ; Male ; Middle Aged ; Obesity/blood ; Obesity/complications ; Overweight/blood ; Overweight/complications ; Platelet Activation/drug effects ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Function Tests
    Chemical Substances Biomarkers ; Platelet Aggregation Inhibitors
    Language English
    Publishing date 2018-07-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034283-7
    ISSN 1369-1635 ; 0953-7104
    ISSN (online) 1369-1635
    ISSN 0953-7104
    DOI 10.1080/09537104.2018.1492108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation of Left Ventricular Overload and Use of Unloading Techniques in Venoarterial Extracorporeal Life Support: A Nationwide Survey.

    Meani, Paolo / Veronese, Giacomo / Todaro, Serena / Marchese, Giuseppe / Mondellini, Giulio M / Protti, Ilaria / de Arroyabe, Blanca Martinez-Lopez / Epis, Francesco / Pappalardo, Federico / Pedrazzini, Giovanna / Munch, Christopher / Margari, Vito / Grazioli, Lorenzo / Lorini, Ferdinando Luca / Cattaneo, Sergio / Montisci, Andrea / Ballotta, Andrea / Raffa, Giuseppe Maria / Carboni, Pietro /
    Lucchelli, Matteo / Avalli, Leonello / Babuin, Luciano / Belliato, Mirko / Bertini, Pietro / Guarracino, Fabio / Paternoster, Gianluca / Ajello, Valentina / Catena, Emanuele / Scolletta, Sabino / Franchi, Federico / Musazzi, Andrea / Pacini, Davide / Sangalli, Fabio / Attisani, Matteo / Rinaldi, Mauro / Grasselli, Giacomo / Mondino, Michele / Ranucci, Marco / Lorusso, Roberto

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2023  Volume 70, Issue 4, Page(s) e57–e60

    MeSH term(s) Humans ; Heart Failure/surgery ; Shock, Cardiogenic ; Heart Ventricles
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000002113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Markers of cardiogenic shock predict persistent acute kidney injury after out of hospital cardiac arrest.

    Roman-Pognuz, Erik / Elmer, Jonathan / Rittenberger, Jon C / Guyette, Francis X / Berlot, Giorgio / De Rosa, Silvia / Peratoner, Alberto / de Arroyabe, Blanca Martinez Lopez / Lucangelo, Umberto / Callaway, Clifton W

    Heart & lung : the journal of critical care

    2018  Volume 48, Issue 2, Page(s) 126–130

    Abstract: Objective: Ischemia and reperfusion injury (IRI) in cardiac arrest patients after return to spontaneous circulation causes dysfunctions in multiple organs. Kidney injury is generally transient but in some patients persists and contributes both to ... ...

    Abstract Objective: Ischemia and reperfusion injury (IRI) in cardiac arrest patients after return to spontaneous circulation causes dysfunctions in multiple organs. Kidney injury is generally transient but in some patients persists and contributes both to mortality and increased resource utilisation. Ongoing shock may compound renal injury from IRI, resulting in persistent dysfunction. We tested whether cardiac dysfunction was associated with the development of persistent acute kidney injury (PAKI) in the first 72 h after cardiac arrest.
    Methods: We performed an observational retrospective study from January 2013 to April 2017. We included consecutive patients treated after out-of-hospital cardiac arrest at a single academic medical center with renal function measured and immediately and for 48 h post arrest. We also recorded each patient's pre arrest baseline creatinine, demographic and clinical characteristics. Our primary outcome of interest was PAKI, defined as acute kidney injury (AKI) on at least 2 measurements 24 h apart. We compared demographics and outcomes between patients with PAKI and those without, and used logistic regression to identify independent predictors of PAKI.
    Results: Of 98 consecutive patients, we excluded 24 for missing data. AKI was present in 75% of subjects on arrival. PAKI developed in 35% of patients. PAKI patients had a longer hospital length of stay (median 21 vs 11 days) and lower hospital survival (47% vs 71%). Serum lactate levels, dosage of adrenaline during resuscitation and days of dobutamine infusion strongly predicted PAKI.
    Conclusions: Among patient who survive cardiac arrest, acute AKI is common and PAKI occurs in more than one third. PAKI is associated both with survival and with length of stay at the hospital. High doses of adrenaline, high serial serum lactate levels, and dose of dobutamine predict PAKI. Evaluation of the trajectory of renal function over the first few days after resuscitation can provide prognostic information about patient recovery.
    MeSH term(s) Acute Kidney Injury/blood ; Acute Kidney Injury/etiology ; Aged ; Biomarkers/blood ; Creatinine/blood ; Female ; Humans ; Male ; Middle Aged ; Out-of-Hospital Cardiac Arrest/complications ; Out-of-Hospital Cardiac Arrest/therapy ; Predictive Value of Tests ; Prognosis ; Resuscitation/methods ; Retrospective Studies ; Risk Factors ; Shock, Cardiogenic/blood ; Shock, Cardiogenic/complications
    Chemical Substances Biomarkers ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2018-11-22
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 193129-5
    ISSN 1527-3288 ; 0147-9563
    ISSN (online) 1527-3288
    ISSN 0147-9563
    DOI 10.1016/j.hrtlng.2018.10.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: European Association of Cardiothoracic Anesthesiology and Intensive Care (EACTAIC) Fellowship Curriculum: Second Edition.

    Erdoes, Gabor / Wouters, Patrick F / Alston, R Peter / Schreiber, Jan-Uwe / Bettex, Dominique / Antoniou, Theofani / Benedetto, Maria / Bouchez, Stefaan / Szegedi, Laszlo / Wilkinson, Kirstin / Landoni, Giovanni / Treskatsch, Sascha / Matute, Purificación / von Dossow, Vera / Van Beersel, Dieter / Unic-Stojanovic, Dragana / Momeni, Mona / Gaudard, Philippe / Szekely, Andrea /
    Burtin, Philippe / Flo-Forner, Anna / Neto, Caetano Nigro / Fassl, Jens / Granell, Manuel / Erb, Joachim M / Navarro-Ripoll, Ricard / Vives, Marc / Fetouh, Fawzia Aboul / Howell, Simon J / Marczin, Nandor / Martinez, Alberto Hernandez / Vuylsteke, Alain / El-Ashmawi, Hossam / de Arroyabe, Blanca Martinez Lopez / Mukherjee, Chirojit / Rex, Steffen / Paternoster, Gianluca / Guarracino, Fabio / El-Tahan, Mohamed R

    Journal of cardiothoracic and vascular anesthesia

    2022  Volume 36, Issue 9, Page(s) 3483–3500

    MeSH term(s) Anesthesia, Cardiac Procedures ; Anesthesiology/education ; Critical Care ; Curriculum ; Fellowships and Scholarships ; Humans ; Internship and Residency
    Language English
    Publishing date 2022-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2022.05.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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