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  1. Article ; Online: Reply to the Editor- Ganglionated Plexus Modulation Inducing Vagal Response During Pulsed Field Ablation for Atrial Fibrillation: A Blessing in Disguise.

    Della Rocca, Domenico G / Del Monte, Alvise / de Asmundis, Carlo / Chierchia, Gian-Battista

    Heart rhythm

    2024  

    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Letter
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2024.03.1785
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Interference from lobe-and-disk left atrial appendage occluder affecting left superior pulmonary vein pulsed field ablation.

    Audiat, Charles / Della Rocca, Domenico Giovanni / de Asmundis, Carlo / Chierchia, Gian Battista

    Heart rhythm

    2024  

    Language English
    Publishing date 2024-04-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2024.03.1808
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  3. Article ; Online: Epicardial open chest ventricular tachycardia ablation in no entry left ventricle.

    Kronenberger, Rani / Pannone, Luigi / de Asmundis, Carlo / La Meir, Mark

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2023  Volume 63, Issue 4

    Abstract: A 57-year-old patient with a history of aortic and mitral mechanical valve replacement was admitted with recurrent implantable cardioverter device shocks and antitachycardia pacing therapies. On electrocardiogram, the clinical ventricular tachycardia (VT) ...

    Abstract A 57-year-old patient with a history of aortic and mitral mechanical valve replacement was admitted with recurrent implantable cardioverter device shocks and antitachycardia pacing therapies. On electrocardiogram, the clinical ventricular tachycardia (VT) was compatible with an antero-lateral peri-mitral basal exit. Because of the inability to access the left ventricle through a percutaneous approach, epicardial VT ablation was performed. The VT and a second VT, consistently induced and coming from the left ventricular apex, were successfully treated with epicardial cryoablation via median sternotomy under cardiopulmonary bypass.
    MeSH term(s) Humans ; Middle Aged ; Heart Ventricles/surgery ; Tachycardia, Ventricular/surgery ; Tachycardia, Ventricular/etiology ; Electrocardiography ; Defibrillators, Implantable/adverse effects ; Catheter Ablation/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-04-25
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezad140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stiff left atrial syndrome with pulmonary veins occlusion after percutaneous radiofrequency ablation: a life-long complication that can lead to heart transplantation.

    Kronenberger, Rani / Tanaka, Kaoru / de Asmundis, Carlo / Meir, Mark La

    Journal of cardiothoracic surgery

    2023  Volume 18, Issue 1, Page(s) 181

    Abstract: Background: Stiff left atrial syndrome (SLAS) and pulmonary vein (PV) occlusion are rare yet potentially major life-long complications after radiofrequency ablation for atrial fibrillation. While mostly controlled by medical management, SLAS can ... ...

    Abstract Background: Stiff left atrial syndrome (SLAS) and pulmonary vein (PV) occlusion are rare yet potentially major life-long complications after radiofrequency ablation for atrial fibrillation. While mostly controlled by medical management, SLAS can progress to refractory congestive heart failure. Treatment of PV stenosis and occlusion remains a challenging problem with ongoing risk for recurrence regardless of techniques employed. Herein we present the case of a now 51-year-old male with acquired PV occlusion and SLAS who, over the course of eleven years, despite multiple interventions, ultimately required heart transplantation.
    Case presentation: After undergoing three radiofrequency catheter procedures for paroxysmal atrial fibrillation (AF), a hybrid ablation was planned due to reappearance of symptomatic AF. Preoperative echocardiography and chest computed tomography (CT) revealed an occlusion of both left PVs. Furthermore, left atrial dysfunction, high pulmonary artery and pulmonary wedge pressures were diagnosed as well as an important reduction of the left atrial volume. The diagnosis of stiff left atrial syndrome was made. Primary surgical repair of the left-sided PVs was performed using a pericardial patch as a tubular neo-vein, combined with cryoablation in the left and right atrium to treat the patient's arrhythmia. Initial results were favorable, however, after two years the patient experienced progressive restenosis with hemoptysis. Therefore, stenting of the common left PV was performed. Over the years, progressive right heart failure with severe tricuspid regurgitation developed, despite maximal medical therapy, which led to the need for heart transplantation.
    Conclusion: The impact of PV occlusion and SLAS after percutaneous radiofrequency ablation can be lifelong and devastating for the clinical course of the patient. Since the presence of a small left atrium could be an important predictor for SLAS in case of redo ablation, preprocedural imaging should guide the operator to an algorithm of a decision-making containing lesion set, energy source, and safety of re-ablation.
    MeSH term(s) Male ; Humans ; Middle Aged ; Pulmonary Veins/surgery ; Atrial Fibrillation/diagnosis ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Heart Atria/surgery ; Radiofrequency Ablation ; Pulmonary Veno-Occlusive Disease/surgery ; Heart Transplantation/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-05-16
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-023-02193-6
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  5. Article ; Online: Brugada syndrome: 30 years of scientific adventure.

    Sieira, Juan / de Asmundis, Carlo / Brugada, Pedro

    Revista espanola de cardiologia (English ed.)

    2022  Volume 75, Issue 12, Page(s) 988–991

    MeSH term(s) Humans ; Brugada Syndrome/diagnosis ; Brugada Syndrome/therapy ; Electrocardiography
    Language Spanish
    Publishing date 2022-09-13
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2022.07.016
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  6. Article: Anti-Arrhythmic Effects of Heart Failure Guideline-Directed Medical Therapy and Their Role in the Prevention of Sudden Cardiac Death: From Beta-Blockers to Sodium-Glucose Cotransporter 2 Inhibitors and Beyond.

    Zaher, Wael / Della Rocca, Domenico Giovanni / Pannone, Luigi / Boveda, Serge / de Asmundis, Carlo / Chierchia, Gian-Battista / Sorgente, Antonio

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Sudden cardiac death (SCD) accounts for a substantial proportion of mortality in heart failure with reduced ejection fraction (HFrEF), frequently triggered by ventricular arrhythmias (VA). This review aims to analyze the pathophysiological mechanisms ... ...

    Abstract Sudden cardiac death (SCD) accounts for a substantial proportion of mortality in heart failure with reduced ejection fraction (HFrEF), frequently triggered by ventricular arrhythmias (VA). This review aims to analyze the pathophysiological mechanisms underlying VA and SCD in HFrEF and evaluate the effectiveness of guideline-directed medical therapy (GDMT) in reducing SCD. Beta-blockers, angiotensin receptor-neprilysin inhibitors, and mineralocorticoid receptor antagonists have shown significant efficacy in reducing SCD risk. While angiotensin-converting enzyme inhibitors and angiotensin receptor blockers exert beneficial impacts on the renin-angiotensin-aldosterone system, their direct role in SCD prevention remains less clear. Emerging treatments like sodium-glucose cotransporter 2 inhibitors show promise but necessitate further research for conclusive evidence. The favorable outcomes of those molecules on VA are notably attributable to sympathetic nervous system modulation, structural remodeling attenuation, and ion channel stabilization. A multidimensional pharmacological approach targeting those pathophysiological mechanisms offers a complete and synergy approach to reducing SCD risk, thereby highlighting the importance of optimizing GDMT for HFrEF. The current landscape of HFrEF pharmacotherapy is evolving, with ongoing research needed to clarify the full extent of the anti-arrhythmic benefits offered by both existing and new treatments.
    Language English
    Publishing date 2024-02-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051316
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  7. Article ; Online: First in human surgical implantation of a leadless pacemaker on the epicardial portion of the right atrial appendage in a patient with a cardiac electronic devices mediated dermatitis.

    Eltsov, Ivan / Sorgente, Antonio / de Asmundis, Carlo / La Meir, Mark

    Interactive cardiovascular and thoracic surgery

    2022  Volume 35, Issue 1

    Abstract: A 33-year-old woman with Sick Sinus Node syndrome and persistent atrial fibrillation underwent a Maze IV procedure in order treat atrial fibrillation and concomitant atrial epicardial implantation of a leadless pacemaker to manage her sinus node ... ...

    Abstract A 33-year-old woman with Sick Sinus Node syndrome and persistent atrial fibrillation underwent a Maze IV procedure in order treat atrial fibrillation and concomitant atrial epicardial implantation of a leadless pacemaker to manage her sinus node insufficiency. Last option has been chosen due to rare pocket complication after previous classic dual-chamber pacemaker implantation.
    MeSH term(s) Adult ; Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Atrial Fibrillation/complications ; Atrial Fibrillation/surgery ; Cardiac Pacing, Artificial/adverse effects ; Dermatitis/complications ; Dermatitis/therapy ; Electronics ; Female ; Humans ; Pacemaker, Artificial/adverse effects ; Sick Sinus Syndrome/complications ; Sick Sinus Syndrome/therapy
    Language English
    Publishing date 2022-02-26
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivac050
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  8. Article ; Online: A novel noncontact high-resolution charge density mapping system to guide ablation of complex atrial arrhythmias: overview of device technology and application.

    Bala, Gezim / De Asmundis, Carlo / Chierchia, Gian-Battista

    Expert review of medical devices

    2021  Volume 18, Issue 4, Page(s) 343–350

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation/instrumentation ; Catheter Ablation/methods ; Clinical Trials as Topic ; Electricity ; Humans ; Ultrasonics
    Language English
    Publishing date 2021-04-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2250857-0
    ISSN 1745-2422 ; 1743-4440
    ISSN (online) 1745-2422
    ISSN 1743-4440
    DOI 10.1080/17434440.2021.1902302
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  9. Article ; Online: Pulsed field ablation: have we finally found the holy grail?

    de Asmundis, Carlo / Chierchia, Gian-Battista

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2021  Volume 23, Issue 11, Page(s) 1691–1692

    Language English
    Publishing date 2021-07-10
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euab169
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  10. Article ; Online: On the Dutch Registry of catheter ablation of atrial fibrillation.

    Jordaens, Luc / de Asmundis, Carlo / Chierchia, Gian-Battista

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2021  Volume 23, Issue 8, Page(s) 1331

    MeSH term(s) Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/surgery ; Catheter Ablation ; Humans ; Registries
    Language English
    Publishing date 2021-03-29
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euab067
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