Article ; Online: Extended pelvic lymph node dissection in robot-assisted radical prostatectomy is an independent risk factor for major complications.
2024 Volume 18, Issue 1, Page(s) 140
Abstract: The aim of this study is to evaluate the major postoperative complication rate after robot-assisted radical prostatectomy (RARP) and to identify related risk factors. A consecutive series of patients who underwent RARP between September 2016 and May 2021, ...
| Abstract | The aim of this study is to evaluate the major postoperative complication rate after robot-assisted radical prostatectomy (RARP) and to identify related risk factors. A consecutive series of patients who underwent RARP between September 2016 and May 2021, with or without extended pelvic lymph node dissection (ePLND) were analyzed for postoperative complications that occurred within 30 days following surgery. Potential risk factors related to complications were identified by means of a multivariate logistic analysis. Electronic medical records were retrospectively reviewed for the occurrence of major complications (Clavien-Dindo grade III or higher) on a per patient level. A multivariate logistic regression with risk factors was performed to identify contributors to complications. In total, 1280 patients were included, of whom 79 (6.2%) experienced at least 1 major complication. Concomitant ePLND was performed in 609 (48%) of patients. The majority of all complications were likely related to the surgical procedure, with anastomotic leakage and lymphoceles being the most common. Upon multivariate analysis, performing ePLND remained the only significant risk factor for the occurrence of major complications (OR 2.26, p = 0.001). In contrast to robot-assisted radical prostatectomy alone, the combination with extended pelvic lymph node dissection (ePLND) has a substantial risk of serious complications. Since the ePLND is performed mainly for staging purpose, the clinical contribution of the ePLND has to be reconsidered with the present use of the PSMA-PET/CT. |
|---|---|
| MeSH term(s) | Male ; Humans ; Robotic Surgical Procedures/methods ; Robotics ; Retrospective Studies ; Positron Emission Tomography Computed Tomography ; Pelvis/surgery ; Lymph Node Excision/adverse effects ; Lymph Node Excision/methods ; Prostatectomy/adverse effects ; Prostatectomy/methods ; Risk Factors |
| Language | English |
| Publishing date | 2024-03-30 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 2268283-1 |
| ISSN | 1863-2491 ; 1863-2483 |
| ISSN (online) | 1863-2491 |
| ISSN | 1863-2483 |
| DOI | 10.1007/s11701-024-01881-2 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.