Article ; Online: Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post-COVID-19 era: an extra challenge for healthcare institutions.
The Journal of hospital infection
2021 Volume 120, Page(s) 43–47
Abstract: The incidence density trend of the carbapenem-resistant Gram-negative bacteria was analysed in device-associated infections and antimicrobial consumption in 99 critical care facilities in a low/middle-income country, between January 2019 and December ... ...
Abstract | The incidence density trend of the carbapenem-resistant Gram-negative bacteria was analysed in device-associated infections and antimicrobial consumption in 99 critical care facilities in a low/middle-income country, between January 2019 and December 2020. Carbapenem-resistant Acinetobacter baumannii (CRAB) per 1000 patient-days increased in 2020 and this finding had a strong positive correlation with the incidence density of COVID-19 by the Spearman test. Polymyxin consumption also increased in 2020 but without significant correlation with CRAB or COVID-19 incidence density, presumably due to empirical and untargeted prescribing as a consequence of concern about CRAB infections. These findings are a warning to infection control programmes and antimicrobial stewardship. |
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MeSH term(s) | Acinetobacter baumannii ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; COVID-19 ; Carbapenems ; Delivery of Health Care ; Drug Resistance, Bacterial ; Gram-Negative Bacteria ; Humans ; Microbial Sensitivity Tests ; SARS-CoV-2 | |||||
Chemical Substances | Anti-Bacterial Agents ; Anti-Infective Agents ; Carbapenems | |||||
Language | English | |||||
Publishing date | 2021-11-19 | |||||
Publishing country | England | |||||
Document type | Journal Article | |||||
ZDB-ID | 779366-2 | |||||
ISSN | 1532-2939 ; 0195-6701 | |||||
ISSN (online) | 1532-2939 | |||||
ISSN | 0195-6701 | |||||
DOI | 10.1016/j.jhin.2021.11.011 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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