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  1. Article ; Online: Isolation and Identification of Pigment-Producing Endophytic Fungi from the Amazonian Species

    de Melo Pereira, Dorothy Ívila / Gurgel, Raiana Silveira / de Souza, Anne Terezinha Fernandes / Matias, Rosiane Rodrigues / de Souza Falcão, Lucas / Chaves, Francisco Celio Maia / da Silva, Gilvan Ferreira / Martínez, José Gregorio / de Lima Procópio, Rudi Emerson / Fantin, Cleiton / Albuquerque, Patrícia Melchionna

    Journal of fungi (Basel, Switzerland)

    2024  Volume 10, Issue 1

    Abstract: Pigments of fungal origin have aroused increasing interest in the food dye and cosmetic industries since the global demand for natural dyes has grown. Endophytic microorganisms are a source of bioactive compounds, and Amazonian plant species can harbor ... ...

    Abstract Pigments of fungal origin have aroused increasing interest in the food dye and cosmetic industries since the global demand for natural dyes has grown. Endophytic microorganisms are a source of bioactive compounds, and Amazonian plant species can harbor fungi with a wide range of biotechnological applications. Popularly known in Brazil as crajiru,
    Language English
    Publishing date 2024-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof10010077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pioneering in vitro characterization of macrophage response induced by scorpion venoms from the Brazilian Amazon.

    Reis, Mouzarllem Barros / Martins, Jonas Gama / Bordon, Karla de Castro Figueiredo / de Campos Fraga-Silva, Thais Fernanda / de Lima Procópio, Rudi Emerson / de Almeida, Bruno Rafael Ribeiro / Bonato, Vânia Luiza Deperon / Arantes, Eliane Candiani

    Toxicon : official journal of the International Society on Toxinology

    2023  Volume 230, Page(s) 107171

    Abstract: There are several scorpion species of medical relevance around the world. Some of them are well characterized by their toxins and clinical outcomes. Brazilian Amazon has a great amount of these arthropods that have an impact in the scorpionism events ... ...

    Abstract There are several scorpion species of medical relevance around the world. Some of them are well characterized by their toxins and clinical outcomes. Brazilian Amazon has a great amount of these arthropods that have an impact in the scorpionism events specifically in this region of Brazil. Recently, several studies pointed out the immune system activation during scorpion envenouming as an important facet of scorpionism, inducing a sepsis-like state that culminates in clinical severity and death. In this work, we characterized the macrophage response of three species of clinical relevance in Brazilian Amazon: Tityus silvestris, T. metuendus and T. obscurus and one specie with no toxic effects to humans, Brotheas amazonicus. All the four species analyzed were able to induce pro- and anti-inflammatory cytokine production in a J774.1 murine macrophage model. This activation was dependent on TLR2/TLR4/MyD88 activation and abolished by TLRs antagonists. These results suggest that the venoms of the four species analyzed were able to induce macrophage response in agreement to the well-established immune activation by T. serrulatus venom. Our findings provide new insights into the clinical repercussions of scorpionism of uncharacterized species and point to new biotechnological applications of these venoms and possible supportive therapies in scorpionism.
    MeSH term(s) Humans ; Mice ; Animals ; Brazil ; Scorpion Venoms/toxicity ; Scorpion Stings ; Scorpions ; Macrophages
    Chemical Substances Scorpion Venoms
    Language English
    Publishing date 2023-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 204479-1
    ISSN 1879-3150 ; 0041-0101
    ISSN (online) 1879-3150
    ISSN 0041-0101
    DOI 10.1016/j.toxicon.2023.107171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 501: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Antimicrobial and Antioxidant Activities of Endophytic Fungi Associated with

    Gurgel, Raiana Silveira / de Melo Pereira, Dorothy Ívila / Garcia, Ana Vyktória França / Fernandes de Souza, Anne Terezinha / Mendes da Silva, Thaysa / de Andrade, Cleudiane Pereira / Lima da Silva, Weison / Nunez, Cecilia Veronica / Fantin, Cleiton / de Lima Procópio, Rudi Emerson / Albuquerque, Patrícia Melchionna

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 8

    Abstract: The endophytic fungal community of the Amazonian medicinal ... ...

    Abstract The endophytic fungal community of the Amazonian medicinal plant
    Language English
    Publishing date 2023-08-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9080864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Characterization of a small cryptic plasmid from endophytic Pantoea agglomerans and its use in the construction of an expression vector.

    de Lima Procópio, Rudi Emerson / Araújo, Welington Luiz / Andreote, Fernando Dini / Azevedo, João Lúcio

    Genetics and molecular biology

    2011  Volume 34, Issue 1, Page(s) 103–109

    Abstract: A circular cryptic plasmid named pPAGA (2,734 bp) was isolated from Pantoea agglomerans strain EGE6 (an endophytic bacterial isolate from eucalyptus). Sequence analysis revealed that the plasmid has a G+C content of 51% and contains four potential ORFs, ... ...

    Abstract A circular cryptic plasmid named pPAGA (2,734 bp) was isolated from Pantoea agglomerans strain EGE6 (an endophytic bacterial isolate from eucalyptus). Sequence analysis revealed that the plasmid has a G+C content of 51% and contains four potential ORFs, 238(A), 250(B), 131(C), and 129(D) amino acids in length without homology to known proteins. The shuttle vector pLGM1 was constructed by combining the pPAGA plasmid with pGFPmut3.0 (which harbors a gene encoding green fluorescent protein, GFP), and the resulting construct was used to over-express GFP in E. coli and P. agglomerans cells. GFP production was used to monitor the colonization of strain EGE6gfp in various plant tissues by fluorescence microscopy. Analysis of EGE6gfp colonization showed that 14 days after inoculation, the strain occupied the inner tissue of Eucalyptus grandis roots, preferentially colonizing the xylem vessels of the host plants.
    Language English
    Publishing date 2011-03-01
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/S1415-47572010005000096
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3079: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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