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  1. Article ; Online: Guide catheter extension use are associated with higher procedural success in chronic total occlusion percutaneous coronary interventions.

    Filho, Evandro M / Araujo, Gustavo N / Machado, Guilherme P / Padilla, Lucio / de Paula, João E T / Botelho, Antonio C / Campos, Carlos M / Quesada, Franklin L H / Alcantara, Marco / Santiago, Ricardo / de Los Santos, Félix D / Oliveira, Marcos D / Ribeiro, Marcelo H / Perez, Luiz / Pinto, Mauro E / Côrtes, Leandro A / Piccaro, Pedro / Brilakis, Emmanouil S / Quadros, Alexandre S

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2024  Volume 103, Issue 4, Page(s) 539–547

    Abstract: Background: Guide catheter extensions (GCEs) increase support and facilitate equipment delivery, but aggressive instrumentation may be associated with a higher risk of complications.: Aim: Our aim was to assess the impact of GCEs on procedural ... ...

    Abstract Background: Guide catheter extensions (GCEs) increase support and facilitate equipment delivery, but aggressive instrumentation may be associated with a higher risk of complications.
    Aim: Our aim was to assess the impact of GCEs on procedural success and complications in patients submitted to chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
    Methods: We analyzed data from the multicenter LATAM CTO Registry. Procedural success was defined as <30% residual stenosis and TIMI 3 distal flow. Major adverse cardiac and cerebrovascular events (MACCE) was defined as the composite of all-cause death, myocardial infarction, target vessel revascularization, and stroke. Propensity score matching (PSM) was used to compare outcomes with and without GCE use.
    Results: From August 2010 to August 2021, 3049 patients were included. GCEs were used in 438 patients (14.5%). In unadjusted analysis, patients in the GCE group were older and had more comorbidities. The median J-CTO score and its components were higher in the GCE group. After PSM, procedural success was higher with GCE use (87.7% vs. 80.5%, p = 0.007). The incidence of coronary perforation (odds ratio [OR]: 1.46, 95% confidence interval [CI]: 0.78-2.71, p = 0.230), bleeding (OR: 1.99, 95% CI: 0.41-2.41, p = 0.986), in-hospital death (OR: 1.39, 95% CI: 0.54-3.62, p = 0.495) and MACCE (OR: 1.07, 95% CI: 0.52-2.19, p = 0.850) were similar in both groups.
    Conclusion: In a contemporary, multicenter cohort of patients undergoing CTO PCI, GCEs were used in older patients, with more comorbidities and complex anatomy. After PSM, GCE use was associated with higher procedural success, and similar incidence of adverse outcomes.
    MeSH term(s) Aged ; Humans ; Catheters ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/therapy ; Coronary Occlusion/etiology ; Hospital Mortality ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2024-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chronic total occlusion percutaneous coronary intervention in Latin America.

    Quadros, Alexandre / Belli, Karlyse C / de Paula, João E T / de Magalhães Campos, Carlos A H / da Silva, Antonio C B / Santiago, Ricardo / Ribeiro, Marcelo H / de Oliveira, Pedro P / Lamelas, Pablo / Abelin, Aníbal P / Bezerra, Cristiano G / Filho, Evandro M / Fuchs, Felipe C / de Los Santos, Félix D / de Andrade, Pedro B / Quesada, Franklin L H / Araya, Mario / Perez, Luis A / Côrtes, Leandro A /
    Zukowski, Cleverson N / Alcantara, Marco / Muniz, Antônio J / Martinelli, Gustavo C / de Carvalho Cantarelli, Marcelo J / Brito, Fábio S / Baradel, Sandra / de Alencar Araripe Falcão, Breno / Mangione, José A / Medeiros, César R / Degrazia, Ramiro C / Lecaro, José A N / Gioppato, Silvio / Ybarra, Luiz F / Weilenmann, Daniel / Gottschall, Carlos A M / Lemke, Viviana / Padilla, Lucio

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2020  Volume 96, Issue 5, Page(s) 1046–1055

    Abstract: Objectives: To report clinical, angiographic characteristics, outcomes, and predictors of unsuccessful procedures in patients who underwent chronic total occlusion (CTO) percutaneous coronary interventions (PCI) in Latin America.: Background: CTO PCI ...

    Abstract Objectives: To report clinical, angiographic characteristics, outcomes, and predictors of unsuccessful procedures in patients who underwent chronic total occlusion (CTO) percutaneous coronary interventions (PCI) in Latin America.
    Background: CTO PCI has been increasingly performed worldwide, but there is a lack of information in this region.
    Methods: An international multicenter registry was developed to collect data on CTO PCI performed in centers in Latin America. Patient, angiographic, procedural and outcome data were evaluated. Predictors of unsuccessful procedures were assessed by multivariable analysis.
    Results: We have included data related to 1,040 CTO PCIs performed in seven countries in Latin America (Argentina, Brazil, Chile, Colombia, Ecuador, Mexico, and Puerto Rico). The mean age was 64 ± 10 years, and CTO PCI was performed mainly for angina control (81%) or treatment of a large ischemic area (30%). Overall technical success rate was 82.5%, and it was achieved with antegrade wire escalation in 81%, antegrade dissection/re-entry in 8% and with retrograde techniques in 11% of the successful procedures. Multivariable analysis identified moderate/severe calcification, a blunt proximal cap and a previous attempt as independent predictors of unsuccessful procedures. In-hospital major adverse cardiovascular events (MACE) occurred in 3.1% of the cases, death in 1% and cardiac tamponade in 0.9% CONCLUSIONS: CTO PCI in Latin America has been performed mainly for ischemia relief. Procedures were associated with a success rate above 80% and low incidence of MACE. Predictors of unsuccessful procedures were similar to those previously reported in the literature.
    MeSH term(s) Aged ; Chronic Disease ; Coronary Angiography ; Coronary Occlusion/diagnostic imaging ; Coronary Occlusion/mortality ; Coronary Occlusion/therapy ; Female ; Hospital Mortality ; Humans ; Latin America ; Male ; Middle Aged ; Myocardial Infarction/mortality ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/mortality ; Registries ; Risk Assessment ; Risk Factors ; Stroke/mortality ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2020-01-28
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.28744
    Database MEDical Literature Analysis and Retrieval System OnLINE

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