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  1. Article ; Online: A targeted approach to vaccine hesitancy.

    Leston, Meredith / de Lusignan, Simon / Hobbs, F D Richard

    Oxford open immunology

    2023  Volume 4, Issue 1, Page(s) iqad007

    Abstract: This short communication makes the case for targeted vaccine research when attempting to counter hesitancy, especially amongst vulnerable or rarefied patient groups. Far from disincentivizing vaccination, the freedom to research and publicize the ... ...

    Abstract This short communication makes the case for targeted vaccine research when attempting to counter hesitancy, especially amongst vulnerable or rarefied patient groups. Far from disincentivizing vaccination, the freedom to research and publicize the limitations of these technologies for certain groups and personalizing dosing, pacing, adjuvants, and time-sensitive alternatives in response is essential for optimizing health outcomes while neutralizing the vaccine research landscape itself. Vaccine evangelism only arouses suspicion when it is not tempered by rigorous research into differential vaccine benefit-risk in this way. That said, the long-standing politicization of vaccination-a topic vulnerable to misinterpretation and media sensationalism-along with the commercial incentives associated with universal adoption makes more comparative and critical research difficult to fund and promote in practice. Likewise, a prescriptive approach to vaccination does little to address the issues of vaccine inequality that contribute to both hesitancy and conspiracy globally and will likely prove financially prohibitive in certain markets. These obstacles are not insurmountable, however, provided that comparative research is centrally subsidized, regulations ensure that vaccine development trials explore differentiated outcomes, especially amongst high-risk or rare groups, and findings are used to prioritize global vaccine allocation to those that stand to benefit most from them.
    Language English
    Publishing date 2023-10-28
    Publishing country England
    Document type Journal Article
    ISSN 2633-6960
    ISSN (online) 2633-6960
    DOI 10.1093/oxfimm/iqad007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lessons from the English primary care sentinel network's response to the COVID-19 pandemic.

    de Lusignan, Simon / Hobbs, Fd Richard / Sheikh, Aziz

    The Lancet. Infectious diseases

    2023  Volume 24, Issue 1, Page(s) 14–16

    MeSH term(s) Humans ; Pandemics ; COVID-19 ; Primary Health Care
    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(23)00736-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correcting flaws in GP funding: avoid missing pockets of deprivation and don't penalise areas with reduced life expectancy.

    Denton, Susan / de Lusignan, Simon

    BMJ (Clinical research ed.)

    2021  Volume 374, Page(s) n1674

    MeSH term(s) General Practice/organization & administration ; Health Care Rationing/organization & administration ; Healthcare Disparities/organization & administration ; Humans ; Life Expectancy
    Language English
    Publishing date 2021-07-02
    Publishing country England
    Document type Letter
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.n1674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The effect of general practice team composition and climate on staff and patient experiences: a systematic review.

    Abrams, Ruth / Jones, Bridget / Campbell, John / de Lusignan, Simon / Peckham, Stephen / Gage, Heather

    BJGP open

    2024  Volume 8, Issue 1

    Abstract: Background: Recent policy initiatives seeking to address the workforce crisis in general practice have promoted greater multidisciplinarity. Evidence is lacking on how changes in staffing and the relational climate in practice teams affect the ... ...

    Abstract Background: Recent policy initiatives seeking to address the workforce crisis in general practice have promoted greater multidisciplinarity. Evidence is lacking on how changes in staffing and the relational climate in practice teams affect the experiences of staff and patients.
    Aim: To synthesise evidence on how the composition of the practice workforce and team climate affect staff job satisfaction and burnout, and the processes and quality of care for patients.
    Design & setting: A systematic literature review of international evidence.
    Method: Four different searches were carried out using MEDLINE, Embase, Cochrane Library, CINAHL, PsycINFO, and Web of Science. Evidence from English language articles from 2012-2022 was identified, with no restriction on study design. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed and data were synthesised thematically.
    Results: In total, 11 studies in primary healthcare settings were included, 10 from US integrated healthcare systems, one from Canada. Findings indicated that when teams are understaffed and work environments are stressful, patient care and staff wellbeing suffer. However, a good relational climate can buffer against burnout and protect patient care quality in situations of high workload. Good team dynamics and stable team membership are important for patient care coordination and job satisfaction. Female physicians are at greater risk of burnout.
    Conclusion: Evidence regarding team composition and team climate in relation to staff and patient outcomes in general practice remains limited. Challenges exist when drawing conclusions across different team compositions and definitions of team climate. Further research is needed to explore the conditions that generate a 'good' climate.
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/BJGPO.2023.0111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Assessment and management of medical emergencies in eating disorders: guidance for GPs.

    Mughal, Faraz / de Lusignan, Simon / Schmidt, Ulrike / Bhui, Kamaldeep

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2023  Volume 73, Issue 730, Page(s) 232–233

    MeSH term(s) Humans ; Emergencies ; Family Practice ; Feeding and Eating Disorders/diagnosis ; Feeding and Eating Disorders/therapy
    Language English
    Publishing date 2023-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp23X732849
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Integrated respiratory surveillance after the COVID-19 pandemic.

    Elson, William / Zambon, Maria / de Lusignan, Simon

    Lancet (London, England)

    2022  Volume 400, Issue 10367, Page(s) 1924–1925

    MeSH term(s) Humans ; COVID-19 ; Pandemics
    Language English
    Publishing date 2022-12-03
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)02325-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: To monitor the COVID-19 pandemic we need better quality primary care data.

    de Lusignan, Simon / Williams, John

    BJGP open

    2020  Volume 4, Issue 2

    Keywords covid19
    Language English
    Publishing date 2020-06-23
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/bjgpopen20X101070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: In this issue: Prerequisites for precision medicine are genomics, computerised medical record systems, and big data analytics.

    De Lusignan, Simon

    Journal of innovation in health informatics

    2018  Volume 24, Issue 4, Page(s) 1009

    MeSH term(s) Big Data ; Genomics ; Humans ; Medical Records Systems, Computerized ; Precision Medicine
    Language English
    Publishing date 2018-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2105081-8
    ISSN 2058-4563 ; 2058-4555
    ISSN (online) 2058-4563
    ISSN 2058-4555
    DOI 10.14236/jhi.v24i4.1009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: In this issue: Digital disparities, complexity and patient safety.

    De Lusignan, Simon

    Journal of innovation in health informatics

    2018  Volume 25, Issue 3, Page(s) 1129

    Abstract: In this issue we publish articles about how digital health and the skills needed to use it may increase disparities. ...

    Abstract In this issue we publish articles about how digital health and the skills needed to use it may increase disparities.
    MeSH term(s) Age Factors ; Comorbidity ; Healthcare Disparities ; Humans ; Patient Safety ; Socioeconomic Factors ; Telemedicine/organization & administration
    Language English
    Publishing date 2018-10-31
    Publishing country England
    Document type Introductory Journal Article
    ZDB-ID 2105081-8
    ISSN 2058-4563 ; 2058-4555
    ISSN (online) 2058-4563
    ISSN 2058-4555
    DOI 10.14236/jhi.v25i3.1129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Real World Evidence to an eHealth tool: The 2017 top ten papers from Journal of Innovation in Health Informatics.

    De Lusignan, Simon

    Journal of innovation in health informatics

    2018  Volume 24, Issue 4, Page(s) 347–349

    Abstract: We report the top ten papers published by the Journal ofInnovation in Health Informatics in 2017. ...

    Abstract We report the top ten papers published by the Journal ofInnovation in Health Informatics in 2017.
    MeSH term(s) Electronic Health Records/utilization ; Humans ; Inventions ; Medical Informatics ; Publications ; Telemedicine/methods
    Language English
    Publishing date 2018-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2105081-8
    ISSN 2058-4563 ; 2058-4555
    ISSN (online) 2058-4563
    ISSN 2058-4555
    DOI 10.14236/jhi.v24i4.1004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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