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  1. Article ; Online: Selective Suppression of Cellular Immunity and Increased Cytotoxicity in Skin Lesions of Disseminated Leishmaniasis Uncovered by Transcriptome-Wide Analysis.

    Ramos, Pablo Ivan Pereira / Cristal, Juqueline Rocha / Khouri, Ricardo / Boaventura, Viviane / Azevedo, Lucas Gentil / Correia, Thaizza Cavalcante / Sharma, Rohit / Cardoso, Cristina R de Barros / Pinzan, Camila Figueiredo / de Noronha, Almério Libório Lopes / Van Weyenbergh, Johan / Queiroz, Artur Trancoso Lopo de / de Oliveira, Camila I / Barral-Netto, Manoel / Barral, Aldina

    The Journal of investigative dermatology

    2021  Volume 141, Issue 10, Page(s) 2542–2546.e5

    MeSH term(s) Humans ; Immunity, Cellular ; Leishmaniasis, Cutaneous/immunology ; Leishmaniasis, Cutaneous/pathology ; Skin/pathology ; Th1 Cells/immunology ; Th2 Cells/immunology ; Transcriptome
    Language English
    Publishing date 2021-04-03
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 80136-7
    ISSN 1523-1747 ; 0022-202X
    ISSN (online) 1523-1747
    ISSN 0022-202X
    DOI 10.1016/j.jid.2021.03.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by

    Nunes, Sara / Silva, Icaro Bonyek / Ampuero, Mariana Rosa / de Noronha, Almério Libório Lopes / de Souza, Lígia Correia Lima / Correia, Thaizza Cavalcante / Khouri, Ricardo / Boaventura, Viviane Sampaio / Barral, Aldina / Ramos, Pablo Ivan Pereira / Brodskyn, Cláudia / Oliveira, Pablo Rafael Silveira / Tavares, Natalia Machado

    Frontiers in immunology

    2018  Volume 9, Page(s) 640

    Abstract: Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about ... ...

    Abstract Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about posttranscriptional regulation during LCL. MicroRNAs (miRNAs) are non-coding small RNAs that regulate gene expression and can be implicated in the pathogenesis of LCL. We investigated the involvement of miRNAs and their targets genes in human LCL using publicly available transcriptome data sets followed by
    MeSH term(s) Biomarkers, Pharmacological ; CD40 Antigens/genetics ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Regulatory Networks ; Humans ; Leishmania braziliensis/physiology ; Leishmaniasis, Cutaneous/drug therapy ; Leishmaniasis, Cutaneous/genetics ; MicroRNAs/genetics ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Skin Physiological Phenomena/genetics ; Treatment Outcome ; Triggering Receptor Expressed on Myeloid Cells-1/genetics ; Wound Healing/genetics
    Chemical Substances Biomarkers, Pharmacological ; CD40 Antigens ; MIRN193 microRNA, human ; MIRN671 microRNA, human ; MicroRNAs ; Receptors, Tumor Necrosis Factor, Type I ; Triggering Receptor Expressed on Myeloid Cells-1
    Language English
    Publishing date 2018-04-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2018.00640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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