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  1. Article ; Online: Een jongen met een zeldzame longziekte.

    van Gansewinkel, Tessa A G / de Rooy, Rick / Latten, Gideon / Krdzalic, Jasenko / Rosias, Philippe R

    Nederlands tijdschrift voor geneeskunde

    2020  Volume 164

    Abstract: Background: In times of coronavirus, a patient with respiratory symptoms whose chest CT scan reveals ground-glass opacities, COVID-19 may seem an obvious diagnosis.: Case description: At the (currently assumed) peak of the coronavirus crisis, a 12- ... ...

    Title translation A boy with a rare pulmonary disease; COVID-19 is clouding our judgment.
    Abstract Background: In times of coronavirus, a patient with respiratory symptoms whose chest CT scan reveals ground-glass opacities, COVID-19 may seem an obvious diagnosis.
    Case description: At the (currently assumed) peak of the coronavirus crisis, a 12-year-old boy was admitted to the hospital twice for severe respiratory symptoms. A chest CT scan revealed ground-glass opacities.COVID-19 pneumonia was initially thought of. However, it turned out to be a rare interstitial pulmonary disease.
    Conclusion: Due to the increased awareness about COVID-19, tunnel vision is lurking. Even during a health crisis, doctors should remain alert to alternative diagnoses.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/physiopathology ; COVID-19/psychology ; COVID-19 Testing ; Child ; Clinical Decision-Making ; Diagnosis, Differential ; Humans ; Judgment ; Lung/diagnostic imaging ; Lung/physiopathology ; Lung Diseases, Interstitial/diagnosis ; Lung Diseases, Interstitial/physiopathology ; Male ; SARS-CoV-2 ; Symptom Assessment/methods ; Tomography, X-Ray Computed/methods
    Language Dutch
    Publishing date 2020-09-17
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 82073-8
    ISSN 1876-8784 ; 0028-2162
    ISSN (online) 1876-8784
    ISSN 0028-2162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Growth, health, and motor development of 5-year-old children born after preimplantation genetic diagnosis.

    Heijligers, Malou / Peeters, Andrea / van Montfoort, Aafke / Nijsten, Joyce / Janssen, Etienne / Gunnewiek, Femke Klein / de Rooy, Rick / van Golde, Ron / Coonen, Edith / Meijer-Hoogeveen, Madelon / Broekmans, Frank / van der Hoeven, Mark / Arens, Yvonne / de Die-Smulders, Christine

    Fertility and sterility

    2019  Volume 111, Issue 6, Page(s) 1151–1158

    Abstract: Objective: To evaluate the growth, health, and motor development of children born after preimplantation genetic diagnosis (PGD).: Design: Observational cohort study and comparison of 5-year-old children born after PGD to similar aged children born ... ...

    Abstract Objective: To evaluate the growth, health, and motor development of children born after preimplantation genetic diagnosis (PGD).
    Design: Observational cohort study and comparison of 5-year-old children born after PGD to similar aged children born after IVF/intracytoplasmic sperm injection (ICSI) and children from families with a genetic disorder born after natural conception (NC).
    Setting: University hospital.
    Patient(s): One hundred three children were included in the PGD group. The two control groups consisted of 90 children born after IVF/ICSI and 58 children born after NC.
    Intervention(s): PGD.
    Main outcome measure(s): We measured height, weight, body circumferences, body mass index, and blood pressure and performed a dysmorphological and neurological examination. We also collected data about the children's medical history, health care consultations, and motor milestones.
    Result(s): The mean height, weight, and body mass index were comparable for all groups. Six (5.8%) PGD, four (4.4%) IVF/ICSI, and five (8.6%) NC children had a major congenital abnormality. The incidence of acute and chronic illnesses was similar in all groups. Motor milestones were achieved on time, but the IVF/ICSI group had a slightly younger mean sitting age. None of the children had severe neurological problems.
    Conclusion(s): Five-year-old children born after PGD show normal growth, health, and motor development when compared with children born after IVF/ICSI and NC children from families with a genetic disorder.
    Trial registration number: NCT02149485.
    MeSH term(s) Age Factors ; Blood Pressure ; Body Height ; Body Mass Index ; Child Development ; Child Health ; Child, Preschool ; Female ; Fertilization in Vitro/adverse effects ; Genetic Diseases, Inborn/diagnosis ; Genetic Diseases, Inborn/genetics ; Genetic Diseases, Inborn/physiopathology ; Genetic Testing ; Health Status ; Humans ; Infertility/diagnosis ; Infertility/physiopathology ; Infertility/therapy ; Male ; Motor Skills ; Preimplantation Diagnosis/methods ; Risk Assessment ; Risk Factors ; Sperm Injections, Intracytoplasmic/adverse effects ; Treatment Outcome ; Weight Gain
    Language English
    Publishing date 2019-04-17
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2019.01.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    ab Jg. 2022: Lesesaal (EG)

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