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  1. Article: Multimodal, open-source big data analysis in asthma: A novel approach to inform public health programming.

    Gangemi, Sebastiano / Tonacci, Alessandro / Costanzo, Giulia / Firinu, Davide / Del Giacco, Stefano

    The World Allergy Organization journal

    2023  Volume 16, Issue 4, Page(s) 100764

    Abstract: Asthma is a chronic respiratory disease affecting over 358 million people worldwide; for this reason analysing big data on asthma from different countries could give a more detailed picture of current disease burden. We aim to investigate the ... ...

    Abstract Asthma is a chronic respiratory disease affecting over 358 million people worldwide; for this reason analysing big data on asthma from different countries could give a more detailed picture of current disease burden. We aim to investigate the correlations between asthma and key socio-demographic parameters from different world databases. We found a direct correlation with the gross domestic product (GDP) per capita and its nominal counterpart, with wealthiest countries seen to have the highest prevalence of asthma, as also confirmed by a similar correlation with the human development index (HDI). A positive correlation was also seen between asthma prevalence and a number of socio-cultural data being representative of a good life quality index and prevalent in more developed and wealthier countries. Concerning medical data, an inverse relationship was seen between asthma prevalence and helminthiasis. Those data indicate a higher prevalence for asthma in more developed countries, where socio-economic status is higher and also the access to medical care is more ubiquitous. The approach used in our study highlighted the role of medical literacy and access to healthcare facilities in the correct diagnosis of asthma and vice versa. Our data appear to be suitable in terms of a health programming approach because of the high burden of disease worldwide.
    Language English
    Publishing date 2023-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2581968-9
    ISSN 1939-4551
    ISSN 1939-4551
    DOI 10.1016/j.waojou.2023.100764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Next generation health guidelines: The role of real-life data in evidence-based medicine.

    Canonica, G Walter / Agache, Ioana / Schünemann, Holger J / Roche, Nicolas / Price, David / Del Giacco, Stefano

    Allergy

    2023  Volume 79, Issue 1, Page(s) 12–14

    MeSH term(s) Humans ; Evidence-Based Medicine ; Practice Guidelines as Topic
    Language English
    Publishing date 2023-09-07
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15887
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exercise, Asthma and the Olympics: A 2000-year-old tale.

    Del Giacco, Stefano

    Porto biomedical journal

    2016  Volume 1, Issue 4, Page(s) 127–128

    Abstract: Two separated phenotypes of Exercise-Induced-Asthma existOlympic Athletes have won more medals than their non-asthmatic peersCompetitive swimmers show an increased asthma prevalenceAsthmatics have no limitations in sports practice if they receive ... ...

    Abstract Two separated phenotypes of Exercise-Induced-Asthma existOlympic Athletes have won more medals than their non-asthmatic peersCompetitive swimmers show an increased asthma prevalenceAsthmatics have no limitations in sports practice if they receive adequate medical treatmentAerobic exercise programs are beneficial for asthmatics and should be included in asthma action plans.
    Language English
    Publishing date 2016-09-01
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2444-8672
    ISSN (online) 2444-8672
    DOI 10.1016/j.pbj.2016.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exercise and physical activity for asthma management: The European Academy of Allergy and Clinical Immunology perspective.

    Price, Oliver J / Del Giacco, Stefano / Gawlik, Radoslaw / Janson, Christer / Odemyr, Mikaela / Papadopoulos, Nikolaos G / Bonini, Matteo

    Allergy

    2023  Volume 78, Issue 11, Page(s) 2823–2825

    MeSH term(s) Humans ; Hypersensitivity/diagnosis ; Hypersensitivity/therapy ; Asthma/diagnosis ; Asthma/therapy ; Exercise ; Allergy and Immunology
    Language English
    Publishing date 2023-06-20
    Publishing country Denmark
    Document type News
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Is hereditary angioedema related to an increased risk of atherosclerosis?

    Bassareo, Pier Paolo / Firinu, Davide / Del Giacco, Stefano

    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

    2019  Volume 122, Issue 2, Page(s) 228–229

    MeSH term(s) Angioedema ; Angioedemas, Hereditary ; Atherosclerosis ; Complement C1 Inhibitor Protein ; Humans ; Vasodilation
    Chemical Substances Complement C1 Inhibitor Protein
    Language English
    Publishing date 2019-01-24
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1228189-x
    ISSN 1534-4436 ; 0003-4738 ; 1081-1206
    ISSN (online) 1534-4436
    ISSN 0003-4738 ; 1081-1206
    DOI 10.1016/j.anai.2018.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cognitive Impairment in People Living with HIV and the Impact of Mood: Results from a Cross-Sectional Study.

    Salis, Francesco / Belfiori, Maristella / Bellisai, Alice / Bernardini, Eleonora / Murtas, Michele / Piras, Rossella / Serreli, Silvia / Ortu, Francesco / Piano, Paola / Del Giacco, Stefano / Mandas, Antonella

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: COVID-19 Clinical Features and Outcome in Italian Patients Treated with Biological Drugs Targeting Type 2 Inflammation.

    Sambugaro, Giada / Brambilla, Elena / Costanzo, Giulia / Bonato, Vera / Ledda, Andrea Giovanni / Del Giacco, Stefano / Scarpa, Riccardo / Rattazzi, Marcello / Favero, Elisabetta / Cinetto, Francesco / Firinu, Davide

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: This is a multicentric investigation involving two Italian centers that examined the clinical course of COVID-19 in patients receiving biological therapy targeting type 2 inflammation and those not receiving biologicals. Since the beginning of the COVID- ... ...

    Abstract This is a multicentric investigation involving two Italian centers that examined the clinical course of COVID-19 in patients receiving biological therapy targeting type 2 inflammation and those not receiving biologicals. Since the beginning of the COVID-19 pandemic, the management of respiratory and allergic disorders and the potential impact of biological therapy in the most severe forms has been a point of uncertainty. Our multicentric investigation aimed to compare the clinical course of COVID-19 and the impact of vaccination in an Italian cohort of patients with atopic disorders caused by a type 2 inflammation, such as eosinophilic asthma, chronic rhinosinusitis with nasal polyposis (CRSwNP), atopic dermatitis (AD), and chronic spontaneous urticaria (CSU). A questionnaire was given to patients coming to our outpatient clinic for the first evaluation or follow-up visit, asking for the clinical characteristics of the infection, the ongoing therapy during the infection, any relevant change, and the patient's vaccination status. We enrolled 132 atopic patients from two Italian centers; 62 patients were on biological therapy at the time of infection (omalizumab 31%, mepolizumab 26%, benralizumab 19%, and dupilumab 24%). The median age was 56 (IQR 22.8) for patients on biologicals and 48 (IQR 26.5) for those not on biologicals (
    Language English
    Publishing date 2024-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14030378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: The Stability of Social and Behavioral Rhythms and Unexpected Low Rate of Relevant Depressive Symptoms in Old Adults during the COVID-19 Pandemic.

    Sancassiani, Federica / Cossu, Giulia / Cantone, Elisa / Romano, Ferdinando / Perra, Alessandra / Urban, Antonio / Pinna, Samantha / Del Giacco, Stefano / Littera, Roberto / Firinu, Davide / Chessa, Luchino / Tramontano, Enzo / Nardi, Antonio Egidio / Carta, Mauro Giovanni

    Journal of clinical medicine

    2024  Volume 13, Issue 7

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13072005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Management of Intermittent and Persistent Asthma in Adolescent and High School Athletes.

    Del Giacco, Stefano / Couto, Mariana / Firinu, Davide / Garcia-Larsen, Vanessa

    The journal of allergy and clinical immunology. In practice

    2020  Volume 8, Issue 7, Page(s) 2166–2181

    Abstract: Asthma is the most common chronic condition during childhood and adolescence, affecting an estimated 8% of children and youngsters below 18 years in the United States and the United Kingdom. In adolescent athletes, asthma-like symptoms may represent a ... ...

    Abstract Asthma is the most common chronic condition during childhood and adolescence, affecting an estimated 8% of children and youngsters below 18 years in the United States and the United Kingdom. In adolescent athletes, asthma-like symptoms may represent a common consequence of regular sport practice. Asthma in young athletes poses several challenges, including the ambiguity of definitions and diagnosis of asthma resulting from exercise-induced symptoms, the best pharmacological treatments, and the nonpharmacological options for the management of disease and the challenges inherent to this age group. At a time when the regular practice of sports is increasingly being recommended for a healthy living, the support network around the young athletes is crucial to reduce the impact of asthma on their physical and emotional well-being. In this review, we examine the main issues around the definitions and clinical differentiations of asthma in young sport athletes. We discuss best practice approaches to improve the adherence to the clinical management, including nonpharmacological strategies directed at the family and trainers of athlete adolescents.
    MeSH term(s) Adolescent ; Asthma/diagnosis ; Asthma/epidemiology ; Asthma/therapy ; Asthma, Exercise-Induced/diagnosis ; Asthma, Exercise-Induced/epidemiology ; Asthma, Exercise-Induced/therapy ; Athletes ; Child ; Humans ; Schools ; United Kingdom ; United States
    Language English
    Publishing date 2020-07-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2020.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Oxidative stress in hereditary angioedema caused by C1 inhibitor deficiency: an interesting finding that deserves further studies.

    Firinu, Davide / Costanzo, Giulia A M L / Del Giacco, Stefano R

    Polish archives of internal medicine

    2020  Volume 130, Issue 2, Page(s) 73–75

    MeSH term(s) Angioedemas, Hereditary ; Bradykinin ; Humans ; Oxidative Stress
    Chemical Substances Bradykinin (S8TIM42R2W)
    Language English
    Publishing date 2020-02-27
    Publishing country Poland
    Document type Editorial ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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