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  1. Article ; Online: Management of Patients With Myocardial Infarction After Coronary Surgery: The Importance of Repeat Revascularization.

    Alfonso, Fernando / Del Val, David

    The American journal of cardiology

    2023  Volume 196, Page(s) 99–101

    MeSH term(s) Humans ; Myocardial Infarction/epidemiology ; Myocardial Infarction/surgery ; Coronary Artery Disease ; Coronary Artery Bypass ; Treatment Outcome ; Myocardial Revascularization ; Percutaneous Coronary Intervention
    Language English
    Publishing date 2023-04-17
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2023.03.020
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  2. Article ; Online: A novel coronary artery healing pattern suggesting the axial progression of coronary plaques.

    Del Val, David / Bastante, Teresa / Alfonso, Fernando

    European heart journal

    2023  Volume 44, Issue 28, Page(s) 2643

    MeSH term(s) Humans ; Coronary Vessels/diagnostic imaging ; Coronary Artery Disease/diagnostic imaging ; Plaque, Atherosclerotic/diagnostic imaging ; Heart ; Coronary Angiography
    Language English
    Publishing date 2023-04-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad218
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    Zs.MO 640: Show issues

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  3. Book ; Online: Relation between PLS and OLS regression in terms of the eigenvalue distribution of the regressor covariance matrix

    del Val, David / Berrendero, José R. / Suárez, Alberto

    2023  

    Abstract: Partial least squares (PLS) is a dimensionality reduction technique introduced in the field of chemometrics and successfully employed in many other areas. The PLS components are obtained by maximizing the covariance between linear combinations of the ... ...

    Abstract Partial least squares (PLS) is a dimensionality reduction technique introduced in the field of chemometrics and successfully employed in many other areas. The PLS components are obtained by maximizing the covariance between linear combinations of the regressors and of the target variables. In this work, we focus on its application to scalar regression problems. PLS regression consists in finding the least squares predictor that is a linear combination of a subset of the PLS components. Alternatively, PLS regression can be formulated as a least squares problem restricted to a Krylov subspace. This equivalent formulation is employed to analyze the distance between ${\hat{\boldsymbol\beta}\;}_{\mathrm{PLS}}^{\scriptscriptstyle {(L)}}$, the PLS estimator of the vector of coefficients of the linear regression model based on $L$ PLS components, and $\hat{\boldsymbol \beta}_{\mathrm{OLS}}$, the one obtained by ordinary least squares (OLS), as a function of $L$. Specifically, ${\hat{\boldsymbol\beta}\;}_{\mathrm{PLS}}^{\scriptscriptstyle {(L)}}$ is the vector of coefficients in the aforementioned Krylov subspace that is closest to $\hat{\boldsymbol \beta}_{\mathrm{OLS}}$ in terms of the Mahalanobis distance with respect to the covariance matrix of the OLS estimate. We provide a bound on this distance that depends only on the distribution of the eigenvalues of the regressor covariance matrix. Numerical examples on synthetic and real-world data are used to illustrate how the distance between ${\hat{\boldsymbol\beta}\;}_{\mathrm{PLS}}^{\scriptscriptstyle {(L)}}$ and $\hat{\boldsymbol \beta}_{\mathrm{OLS}}$ depends on the number of clusters in which the eigenvalues of the regressor covariance matrix are grouped.
    Keywords Statistics - Methodology ; Computer Science - Machine Learning ; Statistics - Machine Learning
    Subject code 519
    Publishing date 2023-12-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Comprehensive clinical assessment of coronary plaque phenotype: integrating optical coherence tomography and intravascular ultrasound co-registration.

    Alfonso, Fernando / Del Val, David / Prati, Francesco

    Coronary artery disease

    2021  Volume 33, Issue 2, Page(s) 125–127

    MeSH term(s) Aged ; Female ; Humans ; Male ; Middle Aged ; Plaque, Atherosclerotic/classification ; Plaque, Atherosclerotic/physiopathology ; Retrospective Studies ; Tomography, Optical Coherence/methods ; Tomography, Optical Coherence/statistics & numerical data ; Ultrasonography, Interventional/methods ; Ultrasonography, Interventional/statistics & numerical data
    Language English
    Publishing date 2021-12-10
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1047268-x
    ISSN 1473-5830 ; 0954-6928
    ISSN (online) 1473-5830
    ISSN 0954-6928
    DOI 10.1097/MCA.0000000000001104
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    Zs.A 3039: Show issues Location:
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  5. Article ; Online: Calcified Nodule: A Rare Clinical Diagnosis in Patients Presenting With ST-Segment Elevation Myocardial Infarction.

    Marschall, Alexander / Rivero, Fernando / Del Val, David / Bastante, Teresa / Cuesta, Javier / Alfonso, Fernando

    JACC. Case reports

    2023  Volume 28, Page(s) 102122

    Abstract: Calcified nodules (CNs) represent the least common cause of acute coronary syndrome. Furthermore, case reports describing CNs as the underlying cause for ST-segment elevation myocardial infarction are exceptional. We present a patient with ST-segment ... ...

    Abstract Calcified nodules (CNs) represent the least common cause of acute coronary syndrome. Furthermore, case reports describing CNs as the underlying cause for ST-segment elevation myocardial infarction are exceptional. We present a patient with ST-segment elevation myocardial infarction caused by a CN and outline the corresponding diagnostic angiographic and intracoronary imaging findings.
    Language English
    Publishing date 2023-11-09
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2023.102122
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  6. Article ; Online: Lithotripsy for calcified in-stent restenosis. The "rock strata peeling pattern": A novel fracture pattern detected by optical coherence tomography.

    Del Val, David / Cuesta, Javier / Roquero, Pilar / Alfonso, Fernando

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2022  Volume 100, Issue 6, Page(s) 1036–1038

    Abstract: Calcified neoatherosclerosis represents a particularly challenging scenario in patients with in-stent restenosis (ISR), frequently associated with worse angiographic and optical coherence tomography (OCT) results compared with other patients with typical ...

    Abstract Calcified neoatherosclerosis represents a particularly challenging scenario in patients with in-stent restenosis (ISR), frequently associated with worse angiographic and optical coherence tomography (OCT) results compared with other patients with typical ISR. Intravascular lithotripsy (IVL) has emerged as a safe and effective technology to circumferentially modify calcium in heavily calcified coronary lesions. Preliminary data also suggest its usefulness in calcified neoatheroscerosis. This case report aims to describe a novel fracture pattern after IVL identified by OCT (the "rock strata peeling pattern") in patients presenting with ISR due to calcified neoatherosclerosis.
    MeSH term(s) Humans ; Tomography, Optical Coherence/methods ; Coronary Restenosis/diagnostic imaging ; Coronary Restenosis/etiology ; Coronary Restenosis/therapy ; Treatment Outcome ; Lithotripsy/methods ; Constriction, Pathologic ; Percutaneous Coronary Intervention/adverse effects ; Coronary Angiography
    Language English
    Publishing date 2022-10-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.30420
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    Zs.A 1226: Show issues Location:
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  7. Article ; Online: Infective Endocarditis After Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review.

    Del Val, David / Panagides, Vassili / Mestres, Carlos A / Miró, José M / Rodés-Cabau, Josep

    Journal of the American College of Cardiology

    2023  Volume 81, Issue 4, Page(s) 394–412

    Abstract: Infective endocarditis (IE) is a rare but serious complication following transcatheter aortic valve replacement (TAVR). Despite substantial improvements in the TAVR procedure (less invasive) and its expansion to younger and healthier patients, the ... ...

    Abstract Infective endocarditis (IE) is a rare but serious complication following transcatheter aortic valve replacement (TAVR). Despite substantial improvements in the TAVR procedure (less invasive) and its expansion to younger and healthier patients, the incidence of IE after TAVR remains stable, with incidence rates similar to those reported after surgical aortic valve replacement. Although IE after TAVR is recognized as a subtype of prosthetic valve endocarditis, this condition represents a particularly challenging scenario given its unique clinical and microbiological profile, the high incidence of IE-related complications, the uncertain role of cardiac surgery, and the dismal prognosis in most patients with TAVR-IE. The number of TAVR procedures is expected to grow exponentially in the coming years, increasing the number of patients at risk of developing this life-threatening complication. Therefore, a detailed understanding of this disease and its complications will be essential to improve clinical outcomes.
    MeSH term(s) Humans ; Transcatheter Aortic Valve Replacement/adverse effects ; Endocarditis, Bacterial/complications ; Heart Valve Prosthesis/adverse effects ; Endocarditis/diagnosis ; Endocarditis/epidemiology ; Endocarditis/etiology ; Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Aortic Valve Stenosis/complications ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2022.11.028
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    Zs.MO 196: Show issues

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  8. Article ; Online: "Lotus root": a novel optical coherence tomography imaging pattern in spontaneous coronary artery dissection.

    Del Val, David / Bastante, Teresa / Rivero, Fernando / Cuesta, Javier / Martinez-Avial, Maria / Alfonso, Fernando

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2023  Volume 18, Issue 17, Page(s) 1458–1459

    MeSH term(s) Humans ; Tomography, Optical Coherence/methods ; Coronary Vessels/diagnostic imaging ; Vascular Diseases/diagnostic imaging ; Coronary Vessel Anomalies/diagnostic imaging ; Coronary Angiography/methods
    Language English
    Publishing date 2023-01-18
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-22-00775
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  9. Article ; Online: Angiographic patterns in spontaneous coronary artery dissection: novel diagnostic insights.

    García-Guimarães, Marcos / Bastante, Teresa / Del Val, David / Fernández-Rodríguez, Diego / Guiberteau-Diaz, Teresa / Salamanca, Jorge / Rivero, Fernando / Alfonso, Fernando

    Expert review of cardiovascular therapy

    2024  Volume 22, Issue 4-5, Page(s) 167–175

    Abstract: Introduction: Spontaneous coronary artery dissection (SCAD) is a rare but well-recognized cause of acute coronary syndrome, especially important in women. Invasive coronary angiography (ICA) is the fundamental diagnostic technique for the confirmation ... ...

    Abstract Introduction: Spontaneous coronary artery dissection (SCAD) is a rare but well-recognized cause of acute coronary syndrome, especially important in women. Invasive coronary angiography (ICA) is the fundamental diagnostic technique for the confirmation of SCAD. Knowing the angiographic patterns suggestive of SCAD is essential for the correct identification of patients with this entity.
    Areas covered: In this narrative review, the main angiographic characteristics of SCAD lesions as detected by ICA are presented and discussed.
    Expert opinion: In addition to the specific angiographic classification of SCAD, several authors have described complementary angiographic patterns suggestive of SCAD. Knowledge and correct identification of these angiographic patterns is essential for the correct diagnosis of patients with clinical suspicion of SCAD.
    MeSH term(s) Humans ; Coronary Angiography/methods ; Coronary Vessel Anomalies/diagnostic imaging ; Vascular Diseases/congenital ; Vascular Diseases/diagnostic imaging ; Vascular Diseases/diagnosis ; Acute Coronary Syndrome/diagnostic imaging ; Female ; Male ; Sex Factors
    Language English
    Publishing date 2024-05-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2024.2349103
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  10. Article ; Online: Paclitaxel-coated balloons: Are all created equal?

    Alfonso, Fernando / Del Val, David / Cortese, Bernardo

    International journal of cardiology

    2020  Volume 322, Page(s) 101–102

    MeSH term(s) Angioplasty, Balloon ; Coronary Vessels ; Humans ; Paclitaxel ; Pharmaceutical Preparations ; Popliteal Artery
    Chemical Substances Pharmaceutical Preparations ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2020-10-19
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2020.10.044
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