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  1. Article ; Online: Recognizing the zebra: a carboplatin-induced haemolytic anaemia.

    Vleeshouwers, A T / den Haan, N G J / Broen, K C J / van de Wouw, A J

    The Netherlands journal of medicine

    2019  Volume 77, Issue 4, Page(s) 150–152

    MeSH term(s) Anemia, Hemolytic/chemically induced ; Anemia, Hemolytic/diagnosis ; Anticarcinogenic Agents/adverse effects ; Carboplatin/adverse effects ; Carcinoma/drug therapy ; Diagnosis, Differential ; Fatal Outcome ; Female ; Humans ; Middle Aged ; Ovarian Neoplasms/drug therapy
    Chemical Substances Anticarcinogenic Agents ; Carboplatin (BG3F62OND5)
    Language English
    Publishing date 2019-09-09
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 193149-0
    ISSN 1872-9061 ; 0300-2977
    ISSN (online) 1872-9061
    ISSN 0300-2977
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 576: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Functional bowel complaints and quality of life after surgery for colon cancer: prevalence and predictive factors.

    van Heinsbergen, M / den Haan, N / Maaskant-Braat, A J / Melenhorst, J / Belgers, E H / Leijtens, J W / Bloemen, J G / Rutten, H J / Bouvy, N D / Janssen-Heijnen, M L / Konsten, J L

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2019  Volume 22, Issue 2, Page(s) 136–145

    Abstract: Aim: Low anterior resection syndrome (LARS) severely affects the quality of life (QoL) of patients after surgery for rectal cancer. There are very few studies that have investigated LARS-like symptoms and their effect on QoL after colon cancer surgery. ... ...

    Abstract Aim: Low anterior resection syndrome (LARS) severely affects the quality of life (QoL) of patients after surgery for rectal cancer. There are very few studies that have investigated LARS-like symptoms and their effect on QoL after colon cancer surgery. The aim of this study was to investigate the prevalence of functional abdominal complaints and related QoL after colon cancer surgery compared with patients with similar complaints after rectal cancer surgery.
    Method: All patients who underwent colorectal cancer resections between January 2008 and December 2015, and who were free of colostomy for at least 1 year, were eligible (n = 2136). Bowel function was assessed by the LARS score, QoL by the EORTC QLQ-C30 and QLQ-CR29 questionnaires. QoL was compared between the LARS score categories and tumour height categories.
    Results: A total of 1495 patients (70.0%) were included in the analyses, of whom 1145 had a colonic and 350 a rectal tumour. Symptoms of LARS were observed in 55% after rectal cancer resection compared with 21% after colon cancer resection. Female gender (OR 1.88, CI 1.392-2.528) and a previous diverting stoma (OR 1.84, CI 1.14-2.97) were independently associated with a higher prevalence of LARS after colon cancer surgery. Patients with LARS after colon cancer surgery performed significantly worse in most QoL domains.
    Conclusion: The results of this study highlight the presence of LARS-like symptoms after surgery for colonic cancer. Patients suffering from major LARS-like symptoms after colon resection reported the same debilitating effect on their QoL as patients with major LARS after rectal resection. This should be addressed by colorectal cancer specialists in order to adequately inform patients.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Colectomy/adverse effects ; Colectomy/psychology ; Colonic Neoplasms/psychology ; Colonic Neoplasms/surgery ; Cross-Sectional Studies ; Defecation ; Female ; Gastrointestinal Diseases/epidemiology ; Gastrointestinal Diseases/etiology ; Gastrointestinal Diseases/psychology ; Humans ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/psychology ; Prevalence ; Proctectomy/adverse effects ; Proctectomy/psychology ; Quality of Life ; Rectal Neoplasms/surgery ; Retrospective Studies ; Risk Factors ; Sex Factors ; Syndrome ; Treatment Outcome
    Language English
    Publishing date 2019-09-03
    Publishing country England
    Document type Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.14818
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5799: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The abundance of arbuscular mycorrhiza in soils is linked to the total length of roots colonized at ecosystem level.

    Barceló, Milagros / van Bodegom, Peter M / Tedersoo, Leho / den Haan, Nadja / Veen, G F Ciska / Ostonen, Ivika / Trimbos, Krijn / Soudzilovskaia, Nadejda A

    PloS one

    2020  Volume 15, Issue 9, Page(s) e0237256

    Abstract: Arbuscular mycorrhizal fungi (AMF) strongly affect ecosystem functioning. To understand and quantify the mechanisms of this control, knowledge about the relationship between the actual abundance and community composition of AMF in the soil and in plant ... ...

    Abstract Arbuscular mycorrhizal fungi (AMF) strongly affect ecosystem functioning. To understand and quantify the mechanisms of this control, knowledge about the relationship between the actual abundance and community composition of AMF in the soil and in plant roots is needed. We collected soil and root samples in a natural dune grassland to test whether, across a plant community, the abundance of AMF in host roots (measured as the total length of roots colonized) is related to soil AMF abundance (using the neutral lipid fatty acids (NLFA) 16:1ω5 as proxy). Next-generation sequencing was used to explore the role of community composition in abundance patterns. We found a strong positive relationship between the total length of roots colonized by AMF and the amount of NLFA 16:1ω5 in the soil. We provide the first field-based evidence of proportional biomass allocation between intra-and extraradical AMF mycelium, at ecosystem level. We suggest that this phenomenon is made possible by compensatory colonization strategies of individual fungal species. Finally, our findings open the possibility of using AMF total root colonization as a proxy for soil AMF abundances, aiding further exploration of the AMF impacts on ecosystems functioning.
    MeSH term(s) Ecosystem ; Mycorrhizae/growth & development ; Soil Microbiology
    Language English
    Publishing date 2020-09-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0237256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Consumer perception of beneficial effects of probiotics for human health.

    Rijkers, G T / Bimmel, D / Grevers, D / den Haan, N / Hristova, Y

    Beneficial microbes

    2013  Volume 4, Issue 1, Page(s) 117–121

    Abstract: The purpose of this study was to evaluate the knowledge, perception and buying behaviour of probiotics. 72 participants in Middelburg, the Netherlands, filled out a detailed questionnaire regarding probiotics and their customer and consumer behaviour. It ...

    Abstract The purpose of this study was to evaluate the knowledge, perception and buying behaviour of probiotics. 72 participants in Middelburg, the Netherlands, filled out a detailed questionnaire regarding probiotics and their customer and consumer behaviour. It can be concluded from this study that the concept of probiotics is generally poorly understood. Health-conscious consumers seem to be the group most aware of the correct meaning of the term probiotics. Almost 50% of the participants did not believe that probiotics had any health effect. Independent organisations and/or government agencies appeared to be the preferred source of information on the functionality of probiotics.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Middle Aged ; Netherlands ; Patient Acceptance of Health Care ; Probiotics/administration & dosage ; Probiotics/pharmacology ; Surveys and Questionnaires ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2013-03-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2561259-1
    ISSN 1876-2891 ; 1876-2883
    ISSN (online) 1876-2891
    ISSN 1876-2883
    DOI 10.3920/BM2012.0050
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7963: Show issues

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