Article ; Online: Association of Selenium and Risk of Esophageal Cancer
Medical Laboratory Journal, Vol 14, Iss 1, Pp 1-
A Review
2020 Volume 9
Abstract: ABSTRACT Esophageal cancer (EC) is one of the most common types of cancer, especially in Asia. Esophageal squamous cell cancer (ESCC) is the most important histological subtype of EC, which accounts for 90% of all EC cases worldwide. ESCC is highly ... ...
| Abstract | ABSTRACT Esophageal cancer (EC) is one of the most common types of cancer, especially in Asia. Esophageal squamous cell cancer (ESCC) is the most important histological subtype of EC, which accounts for 90% of all EC cases worldwide. ESCC is highly prevalent in Turkey, Iran, Kazakhstan and northern and central parts of China. Selenium is an essential micronutrient that is required for cellular functioning and synthesis of several selenoproteins. It also modulates the antioxidant defense system, cell cycle and apoptosis. This article reviews the most important molecular mechanisms of EC and investigates the association between selenium level and incidence of EC in high-risk areas. Keywords: Esophageal cancer, selenium, selenoprotein. |
|---|---|
| Keywords | esophageal cancer ; selenium ; selenoprotein ; Medicine ; R |
| Language | English |
| Publishing date | 2020-01-01T00:00:00Z |
| Publisher | Golestan University of Medical Sciences |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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