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  1. Article ; Online: Centralization and Quality Control in Esophageal Cancer Surgery: a Way Forward in Europe.

    Visser, Maurits R / van Berge Henegouwen, Mark I / van Hillegersberg, Richard

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2024  

    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doae035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnosis and management of pancreatic insufficiency in patients with gastrectomy due to cancer or gastric ulcers: a virtual roundtable expert discussion.

    Croagh, Daniel / Michalski, Christoph W / van Berge Henegouwen, Mark I / Alfieri, Sergio

    Expert review of gastroenterology & hepatology

    2024  Volume 17, Issue 12, Page(s) 1313–1319

    Abstract: Introduction: Pancreatic exocrine insufficiency (PEI) is common after gastric resection for cancer or ulcers but is under-recognized and undertreated. Although pancreatic enzyme replacement therapy (PERT) is the mainstay of PEI management, robust ... ...

    Abstract Introduction: Pancreatic exocrine insufficiency (PEI) is common after gastric resection for cancer or ulcers but is under-recognized and undertreated. Although pancreatic enzyme replacement therapy (PERT) is the mainstay of PEI management, robust evidence supporting its use after gastric surgery is limited.
    Areas covered: In the absence of guideline recommendations specific for patients with pancreatic insufficiency after gastrectomy, a panel of experts from different geographical regions convened in a virtual meeting to discuss their approach to patient management.
    Expert opinion: Pancreatic insufficiency after gastrointestinal surgery is not a simple post-surgical complication as several factors contribute to its development. Although the pancreas is unimpaired after gastrectomy, it cannot function normally in the altered environment. Pancreatic insufficiency can be challenging to diagnose in gastrectomy patients due to nonspecific symptoms and the absence of a simple diagnostic test. Fecal elastase appears to be the default test, although it is not sufficiently sensitive nor reliable for diagnosing or monitoring PEI. Patients with maldigestion symptoms after gastrectomy are treated pragmatically: those with clinical suspicion of pancreatic insufficiency receive a trial of PERT and are monitored for symptom improvement. There is a clear need for high-quality evidence from clinical trials to guide the management of this patient population.
    MeSH term(s) Humans ; Stomach Ulcer ; Exocrine Pancreatic Insufficiency/diagnosis ; Exocrine Pancreatic Insufficiency/etiology ; Exocrine Pancreatic Insufficiency/therapy ; Pancreas ; Gastrectomy/adverse effects ; Neoplasms/complications
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2481021-6
    ISSN 1747-4132 ; 1747-4124
    ISSN (online) 1747-4132
    ISSN 1747-4124
    DOI 10.1080/17474124.2023.2296762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: History and evidence for state of the art of lymphadenectomy in esophageal cancer surgery.

    Schuring, Nannet / van Berge Henegouwen, Mark I / Gisbertz, Suzanne S

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2023  Volume 37, Issue 4

    Abstract: The current curative multimodal treatment of advanced esophageal cancers consists of neoadjuvant or perioperative chemo(radio)therapy followed by a radical surgical resection of the primary tumor and a 2- or 3-field lymphadenectomy. One of the most ... ...

    Abstract The current curative multimodal treatment of advanced esophageal cancers consists of neoadjuvant or perioperative chemo(radio)therapy followed by a radical surgical resection of the primary tumor and a 2- or 3-field lymphadenectomy. One of the most important predictors of long-term survival of esophageal cancer patients is lymph node involvement. The distribution pattern of lymph node metastases in esophageal cancer is unpredictable and depends on the primary tumor location, histology, T-stage and application of neoadjuvant or perioperative treatment. The optimal extent of the lymphadenectomy remains controversial; there is no global consensus on this topic yet. Some surgeons advocate an aggressive and extended lymph node dissection to remove occult metastatic disease, to optimize oncological outcomes. Others promote a more restricted lymphadenectomy, since the benefit of an extended lymphadenectomy, especially after neoadjuvant chemoradiotherapy, has not been clearly demonstrated, and morbidity may be reduced. In this review, we describe the development of lymphadenectomy, followed by a summary of current evidence for lymphadenectomy in esophageal cancer treatment.
    MeSH term(s) Humans ; Esophagectomy ; Lymph Node Excision ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Esophageal Neoplasms/surgery
    Language English
    Publishing date 2023-12-04
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doad065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ASO Author Reflections: Safety of Performing Esophageal Cancer Surgery During the First Wave of the COVID-19 Pandemic in Europe: A Multicenter Study.

    Borgstein, Alexander B J / van Berge Henegouwen, Mark I

    Annals of surgical oncology

    2021  Volume 28, Issue 9, Page(s) 4814–4815

    MeSH term(s) COVID-19 ; Esophageal Neoplasms/epidemiology ; Esophageal Neoplasms/surgery ; Esophagectomy ; Europe/epidemiology ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-03-24
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-09891-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: ASO Author Reflections: Failure to Cure in Patients Undergoing Surgery for Gastric Cancer: A Nationwide Cohort Study.

    Voeten, Daan M / van Berge Henegouwen, Mark I

    Annals of surgical oncology

    2021  Volume 28, Issue 8, Page(s) 4497–4498

    MeSH term(s) Cohort Studies ; Humans ; Stomach Neoplasms/surgery
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-09539-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Analgesia in esophagectomy: a narrative review.

    Feenstra, Minke L / van Berge Henegouwen, Mark I / Hollmann, Markus W / Hermanides, Jeroen / Eshuis, Wietse J

    Journal of thoracic disease

    2023  Volume 15, Issue 9, Page(s) 5099–5111

    Abstract: Background and objective: Optimal pain management for esophagectomy facilitates prevention of postoperative complications such as pneumonia, but also chronic pain. Historically, multimodal intravenous analgesia was employed. In the last decades, ... ...

    Abstract Background and objective: Optimal pain management for esophagectomy facilitates prevention of postoperative complications such as pneumonia, but also chronic pain. Historically, multimodal intravenous analgesia was employed. In the last decades, regional anesthesia including epidural and paravertebral analgesia is frequently used. In this narrative review, we provide a comprehensive overview of the available evidence for the different analgesia regimens for esophagectomy.
    Methods: A search was conducted in the PubMed/MEDLINE database in November 2022. Only reports in English or Dutch were included. Editorials or articles lacking full text were excluded. A review of different analgesia regimens after esophagectomy is provided.
    Key content and findings: Epidural analgesia (EA) was suggested to reduce postoperative pneumonia and prevent chronic postsurgical pain (CPSP) as compared to opioid-based systemic analgesia and was considered the gold standard of pain management for esophagectomy. In the last decades, the side-effects of EA became more evident. Next to mild or moderate side-effects such as hypotension and urinary retention, several reports emphasized the incidence of serious neurologic complications to be much higher than estimated before. In addition, minimally invasive surgery fostered that other regional analgesia (RA) techniques are potential alternatives for EA. Paravertebral catheter placement can be performed under videoscope view during the thoracic phase of esophagectomy, making it a safe and easily placed block. Evidence on the effectiveness of erector spinae plane block (ESPB) is limited in this context.
    Conclusions: Several analgesia regimens after esophagectomy are described. EA is most common, however paravertebral analgesia is a good alternative. Other techniques are also gaining ground but randomized clinical trials are lacking. Future studies should focus on the efficacy of paravertebral and erector spinae blocks for postoperative pain management for esophagectomy.
    Language English
    Publishing date 2023-09-01
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-23-241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Reply to B. P. L. Wijnhoven et al and F. Nuytens et al.

    Markar, Sheraz R / van Berge Henegouwen, Mark I

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2020  Volume 39, Issue 1, Page(s) 92–93

    MeSH term(s) Esophagectomy ; Humans
    Language English
    Publishing date 2020-09-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.20.02354
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  8. Article ; Online: Textbook outcome for esophageal cancer surgery: an international consensus-based update of a quality measure.

    Kalff, Marianne C / van Berge Henegouwen, Mark I / Gisbertz, Suzanne S

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2021  Volume 34, Issue 7

    Abstract: Textbook outcome for esophageal cancer surgery is a composite quality measure including 10 short-term surgical outcomes reflecting an uneventful perioperative course. Achieved textbook outcome is associated with improved long-term survival. This study ... ...

    Abstract Textbook outcome for esophageal cancer surgery is a composite quality measure including 10 short-term surgical outcomes reflecting an uneventful perioperative course. Achieved textbook outcome is associated with improved long-term survival. This study aimed to update the original textbook outcome based on international consensus. Forty-five international expert esophageal cancer surgeons received a personal invitation to evaluate the 10 items in the original textbook outcome for esophageal cancer surgery and to rate 18 additional items divided over seven subcategories for their importance in the updated textbook outcome. Items were included in the updated textbook outcome if ≥80% of the respondents agreed on inclusion. In case multiple items within one subcategory reached ≥80% agreement, only the most inclusive item with the highest agreement rate was included. With a response rate of 80%, 36 expert esophageal cancer surgeons, from 34 hospitals, 16 countries, and 4 continents responded to this international survey. Based on the inclusion criteria, the updated quality indicator 'textbook outcome for esophageal cancer surgery' should consist of: tumor-negative resection margins, ≥20 lymph nodes retrieved and examined, no intraoperative complication, no complications Clavien-Dindo ≥III, no ICU/MCU readmission, no readmission related to the surgical procedure, no anastomotic leakage, no hospital stay ≥14 days, and no in-hospital mortality. This study resulted in an international consensus-based update of a quality measure, textbook outcome for esophageal cancer surgery. This updated textbook outcome should be implemented in quality assurance programs for centers performing esophageal cancer surgery, and could standardize quality measures used internationally.
    MeSH term(s) Consensus ; Esophageal Neoplasms/surgery ; Esophagectomy ; Gastrectomy ; Humans ; Postoperative Complications ; Quality Indicators, Health Care ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doab011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Improved anastomotic leakage rates after the "flap and wrap" reconstruction in Ivor Lewis esophagectomy for cancer.

    Slaman, Annelijn E / Eshuis, Wietse J / van Berge Henegouwen, Mark I / Gisbertz, Suzanne S

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2022  

    Abstract: Anastomotic leakage after esophagectomy has serious consequences. In Ivor Lewis esophagectomy, a shorter and possibly better vascularized gastric conduit is created than in McKeown esophagectomy. Intrathoracic anastomoses can additionally be wrapped in ... ...

    Abstract Anastomotic leakage after esophagectomy has serious consequences. In Ivor Lewis esophagectomy, a shorter and possibly better vascularized gastric conduit is created than in McKeown esophagectomy. Intrathoracic anastomoses can additionally be wrapped in omentum and concealed behind the pleura ("flap and wrap" reconstruction). Aims of this observational study were to assess the anastomotic leakage incidence after transhiatal esophagectomy (THE), McKeown esophagectomy (McKeown), Ivor Lewis esophagectomy (IL) without "flap and wrap" reconstruction, and IL with "flap and wrap" reconstruction. Consecutive patients undergoing esophagectomy at a tertiary referral center between January 2013 and April 2019 were included. Primary outcome was the anastomotic leakage rate. Secondary outcomes were postoperative outcomes, mortality, and 3-year overall survival. A total of 463 patients were included. The anastomotic leakage incidence after THE (n = 37), McKeown (n = 97), IL without "flap and wrap" reconstruction (n = 39), and IL with "flap and wrap" reconstruction (n = 290) were 24.3, 32.0, 28.2, and 7.2% (P < 0.001). THE and IL with "flap and wrap" reconstruction required fewer reoperations for anastomotic leakage (0 and 1.4%) than McKeown and IL without "flap and wrap" reconstruction (6.2 and 17.9%, P < 0.001). Fewer anastomotic leakages are observed after Ivor Lewis esophagectomy with "flap and wrap" reconstruction compared to transhiatal, McKeown and Ivor Lewis esophagectomy without "flap and wrap" reconstruction. The "flap and wrap" reconstruction seems a promising technique to further reduce anastomotic leakages and its severity in esophageal cancer patients who have an indication for Ivor Lewis esophagectomy.
    Language English
    Publishing date 2022-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doac036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Author response to: Comment on: Outcomes after totally minimally invasive versus hybrid and open Ivor Lewis oesophagectomy: results from the International Esodata Study Group.

    van der Wilk, Berend J / Lagarde, Sjoerd M / van Berge Henegouwen, Mark I

    The British journal of surgery

    2022  Volume 110, Issue 1, Page(s) 118

    MeSH term(s) Humans ; Esophagectomy/methods ; Esophageal Neoplasms/surgery ; Minimally Invasive Surgical Procedures/methods ; Postoperative Complications/surgery ; Retrospective Studies ; Laparoscopy/methods ; Treatment Outcome
    Language English
    Publishing date 2022-10-19
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znac338
    Database MEDical Literature Analysis and Retrieval System OnLINE

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