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  1. Article ; Online: Outpatient Video Visits During the COVID-19 Pandemic: Cross-Sectional Survey Study of Patients' Experiences and Characteristics.

    van den Bosch, Stefanie C / van Dalen, Demi / Meinders, Marjan / van Goor, Harry / Bergé, Stefaan / Stommel, Martijn / van Dulmen, Sandra

    Journal of medical Internet research

    2024  Volume 26, Page(s) e49058

    Abstract: Background: During the first lockdown of the COVID-19 pandemic, an exponential increase in video consultations replacing in-person outpatient visits was observed in hospitals. Insight into patients' experiences with this type of consultation is helpful ... ...

    Abstract Background: During the first lockdown of the COVID-19 pandemic, an exponential increase in video consultations replacing in-person outpatient visits was observed in hospitals. Insight into patients' experiences with this type of consultation is helpful for a broad, sustainable, and patient-centered implementation of video consultation.
    Objective: This study aims to examine patients' experiences with video consultation during the COVID-19 pandemic and identify discriminative patient and consultation characteristics to determine when video consultation is most feasible.
    Methods: A cross-sectional survey study was conducted. Patients aged ≥18 years and scheduled for a video consultation at the outpatient clinic of a Dutch university medical center from August 2020 to December 2020 for all medical specialties were eligible. Patients' experiences were explored through a study-specific survey using descriptive quantitative statistics. Open-ended questions were qualitatively analyzed and thematically categorized into appreciated aspects and aspects for improvement. Discriminative patient and consultation characteristics were identified using 3 distinctive survey items. Characteristics of patients who scored and those who did not score all 3 items positively were analyzed using binary logistic regression.
    Results: A total of 1054 patients were included in the analysis. Most patients (964/1054, 91.46%) were satisfied with their video consultation, with a mean overall grade of 8.6 (SD 1.3) of 10. In the qualitative analyses, 70.02% (738/1054) of the patients cited aspects they appreciated and 44.97% (474/1054) mentioned aspects for improvement during their consultation. Patients with better self-rated health reported a positive evaluation significantly more often (P=.001), which also held true for other medical specialties (vs surgical and nonsurgical specialties; P<.001).
    Conclusions: Video consultation was perceived as highly satisfactory by patients during the COVID-19 pandemic, with the best experience reported by healthy participants and those undergoing their first consultation. Appreciated aspects are mainly at the individual professional level, organizational level, and innovation level itself. The aspects that were mentioned for improvement can be changed for the better.
    MeSH term(s) Humans ; Adolescent ; Adult ; Outpatients ; Cross-Sectional Studies ; Pandemics ; COVID-19 ; Communicable Disease Control
    Language English
    Publishing date 2024-03-27
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/49058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Designing a video consultation area for hybrid care delivery: the Garden Room with a view.

    Smits, Merlijn / van Dalen, Demi / Popping, Danny / Bleeker, René / Stommel, Martijn W J / van Goor, Harry

    Frontiers in digital health

    2023  Volume 5, Page(s) 1198565

    Abstract: Introduction: Accelerated by the coronavirus pandemic, the healthcare landscape is rapidly evolving, with a shift towards hybrid care models combining in-person and online care. To support this shift, the Radboudumc, an academic hospital in the ... ...

    Abstract Introduction: Accelerated by the coronavirus pandemic, the healthcare landscape is rapidly evolving, with a shift towards hybrid care models combining in-person and online care. To support this shift, the Radboudumc, an academic hospital in the Netherlands, decided to redesign an existing space facilitating the conduction of video consultations.
    Method: The design process involved participation of end-users to ensure that the physical space met their needs. The look and feel of the area was based on evidence-based design guidelines. Two prototype setups were built and tested, and the feedback informed the final design of the Garden Room.
    Results: Identified end-user needs were divided into 3 major categories entailing consultation room setup, optimal use of technology and practical issues involving room availability. Combined with the look and feel of the hospital, final design requirements were developed. The Garden Room consists of 18 video consultation rooms, 4 shared workspaces, relaxation area with kitchen, and meeting rooms. Specific attention is given to the ergonomics, technology and privacy in the rooms to facilitate optimal video conversations between patients and healthcare providers. In the Garden Room, natural elements and an open design supports working in a healing environment.
    Discussion: Next challenge will be optimizing the use of the Garden Room, which may be hindered by various barriers like resistance to change, existing work processes, and lack of skills training. To address these barriers and support use of the Garden Room, the hospital should focus on the implementation of education, changes in work processes, and the presence of advocates for telehealth.
    Language English
    Publishing date 2023-07-25
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-253X
    ISSN (online) 2673-253X
    DOI 10.3389/fdgth.2023.1198565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The inter-rater and test-retest reliability of skin thickness and skin elasticity measurements by the DermaLab Combo in healthy participants.

    Peperkamp, Kirsten / Verhulst, Arico C / Tielemans, Hanneke J P / Winters, Harm / van Dalen, Demi / Ulrich, Dietmar J O

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

    2019  Volume 25, Issue 6, Page(s) 787–792

    Abstract: Background: For several purposes, skin parameters like thickness and elasticity can be measured. However, little is known about the accuracy of those measurements.: Aim: The aim of this study was to determine the intrarater and test-retest ... ...

    Abstract Background: For several purposes, skin parameters like thickness and elasticity can be measured. However, little is known about the accuracy of those measurements.
    Aim: The aim of this study was to determine the intrarater and test-retest reliability of skin thickness and elasticity measurements performed with the DermaLab Combo®.
    Methods: A total of 49 participants were included in this study. Skin thickness and elasticity were measured at six defined locations on the dominant arm. Measurements were repeated two times by the same observer to determine the test-retest reliability. To determine the inter-rater reliability, a second observer repeated the measurements once.
    Results: Inter-rater and test-retest reliability for elasticity measurements fluctuates per location and per parameter: Inter-rater intraclass correlation coefficient (ICC) ranged from 0.23 to 0.80, and test-retest ICC ranged from 0.25 to 0.84. Skin thickness was measured reliable by every observer on every location, with a test-retest ICC ranging from 0.71 to 0.83 and an inter-rater ICC ranging from 0.69 to 0.80.
    Conclusion: The DermaLab Combo® showed a good inter-rater reliability when measuring skin thickness and elasticity. Not all locations are suitable for reliable inter-rater or test-retest measurements. The device is difficult to use by inexperienced users, as the echo probe is sensitive to small movements.
    MeSH term(s) Adult ; Aged ; Arm/diagnostic imaging ; Arm/physiology ; Diagnostic Imaging/instrumentation ; Diagnostic Imaging/methods ; Elasticity/physiology ; Equipment Design ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Observer Variation ; Reproducibility of Results ; Skin/diagnostic imaging ; Young Adult
    Language English
    Publishing date 2019-05-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1229160-2
    ISSN 1600-0846 ; 0909-752X ; 1397-1344
    ISSN (online) 1600-0846
    ISSN 0909-752X ; 1397-1344
    DOI 10.1111/srt.12718
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4278: Show issues Location:
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  4. Article ; Online: Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate.

    van den Berg, Fons F / van Dalen, Demi / Hyoju, Sanjiv K / van Santvoort, Hjalmar C / Besselink, Marc G / Wiersinga, Willem Joost / Zaborina, Olga / Boermeester, Marja A / Alverdy, John

    Gut

    2020  Volume 70, Issue 5, Page(s) 915–927

    Abstract: Objective: The gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising ... ...

    Abstract Objective: The gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising pancreatitis and its reversal by butyrate supplementation.
    Design: C57BL/6 mice were fed either standard chow or a Western-type diet for 4 weeks and were then subjected to taurocholate-induced necrotising pancreatitis. Blood and pancreas were collected for bacteriology and immune analysis. The cecum microbiota composition of mice was analysed using 16S rRNA gene amplicon sequencing and cecal content metabolites were analysed by targeted (ie, butyrate) and untargeted metabolomics. Prevention of necrotising pancreatitis in this model was compared between faecal microbiota transplantation (FMT) from healthy mice, antibiotic decontamination against Gram-negative bacteria and oral or systemic butyrate administration. Additionally, the faecal microbiota of patients with pancreatitis and healthy subjects were analysed.
    Results: Mortality, systemic inflammation and bacterial dissemination were increased in mice fed Western diet and their gut microbiota were characterised by a loss of diversity, a bloom of
    Conclusion: Butyrate depletion and its repletion appear to play a central role in disease progression towards necrotising pancreatitis.
    MeSH term(s) Animals ; Butyrates/pharmacology ; Diet, Western ; Disease Models, Animal ; Disease Progression ; Fecal Microbiota Transplantation ; Gastrointestinal Microbiome ; Humans ; Mice ; Mice, Inbred C57BL ; Pancreatitis, Acute Necrotizing/diet therapy ; Pancreatitis, Acute Necrotizing/microbiology ; Pancreatitis, Acute Necrotizing/mortality ; Phenotype
    Chemical Substances Butyrates
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2019-320430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 160: Show issues Location:
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  5. Article ; Online: Preoperative misdiagnosis of pancreatic and periampullary cancer in patients undergoing pancreatoduodenectomy: A multicentre retrospective cohort study.

    van Roessel, Stijn / Soer, Eline C / Daamen, Lois A / van Dalen, Demi / Fariña Sarasqueta, Arantza / Stommel, Martijn W J / Molenaar, I Quintus / van Santvoort, Hjalmar C / van de Vlasakker, Vincent C J / de Hingh, Ignace H J T / Groen, Jesse V / Mieog, J Sven D / van Dam, Jacob L / van Eijck, Casper H J / van Tienhoven, Geertjan / Klümpen, Heinz-Josef / Wilmink, Johanna W / Busch, Olivier R / Brosens, Lodewijk A A /
    Groot Koerkamp, Bas / Verheij, Joanne / Besselink, Marc G

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2021  Volume 47, Issue 10, Page(s) 2525–2532

    Abstract: Introduction: Whereas neoadjuvant chemo(radio)therapy is increasingly used in pancreatic cancer, it is currently not recommended for other periampullary (non-pancreatic) cancers. This has important implications for the relevance of the preoperative ... ...

    Abstract Introduction: Whereas neoadjuvant chemo(radio)therapy is increasingly used in pancreatic cancer, it is currently not recommended for other periampullary (non-pancreatic) cancers. This has important implications for the relevance of the preoperative diagnosis for pancreatoduodenectomy. This retrospective multicentre cohort study aimed to determine the frequency of clinically relevant misdiagnoses in patients undergoing pancreatoduodenectomy for pancreatic or other periampullary cancer.
    Methods: Data from all consecutive patients who underwent a pancreatoduodenectomy between 2014 and 2018 were obtained from the prospective Dutch Pancreatic Cancer Audit. The preoperative diagnosis as concluded by the multidisciplinary team (MDT) meeting was compared with the final postoperative diagnosis at pathology to determine the rate of clinically relevant misdiagnosis (defined as missed pancreatic cancer or incorrect diagnosis of pancreatic cancer).
    Results: In total, 1244 patients underwent pancreatoduodenectomy of whom 203 (16%) had a clinically relevant misdiagnosis preoperatively. Of all patients with a final diagnosis of pancreatic cancer, 13% (87/679) were preoperatively misdiagnosed as distal cholangiocarcinoma (n = 41, 6.0%), ampullary cancer (n = 27, 4.0%) duodenal cancer (n = 16, 2.4%), or other (n = 3, 0.4%). Of all patients with a final diagnosis of periampullary (non-pancreatic) cancer, 21% (116/565) were preoperatively incorrectly diagnosed as pancreatic cancer. Accuracy of preoperative diagnosis was 84% for pancreatic cancer, 71% for distal cholangiocarcinoma, 73% for ampullary cancer and 73% for duodenal cancer. A prediction model for the preoperative likelihood of pancreatic cancer (versus other periampullary cancer) prior to pancreatoduodenectomy demonstrated an AUC of 0.88.
    Discussion: This retrospective multicentre cohort study showed that 16% of patients have a clinically relevant misdiagnosis that could result in either missing the opportunity of neoadjuvant chemotherapy in patients with pancreatic cancer or inappropriate administration of neoadjuvant chemotherapy in patients with non-pancreatic periampullary cancer. A preoperative prediction model is available on www.pancreascalculator.com.
    MeSH term(s) Aged ; Ampulla of Vater ; Blood Vessels/diagnostic imaging ; Cholangiocarcinoma/diagnosis ; Cholangiocarcinoma/surgery ; Common Bile Duct Neoplasms/diagnosis ; Common Bile Duct Neoplasms/surgery ; Diagnostic Errors/statistics & numerical data ; Duodenal Neoplasms/diagnosis ; Duodenal Neoplasms/surgery ; Endoscopic Ultrasound-Guided Fine Needle Aspiration ; Female ; Humans ; Male ; Middle Aged ; Pancreas/blood supply ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery ; Pancreaticoduodenectomy ; Predictive Value of Tests ; Preoperative Period ; Retrospective Studies ; Survival Rate ; Tumor Burden
    Language English
    Publishing date 2021-03-15
    Publishing country England
    Document type Journal Article ; Multicenter Study
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2021.03.228
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