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  1. Article: Molecular imaging as biomarker for treatment response and outcome in breast cancer.

    van Geel, Jasper J L / de Vries, Erik F J / van Kruchten, Michel / Hospers, Geke A P / Glaudemans, Andor W J M / Schröder, Carolina P

    Therapeutic advances in medical oncology

    2023  Volume 15, Page(s) 17588359231170738

    Abstract: Molecular imaging, such as positron emission tomography (PET), is increasingly used as biomarker to predict and assess treatment response in breast cancer. The number of biomarkers is expanding with specific tracers for tumour characteristics throughout ... ...

    Abstract Molecular imaging, such as positron emission tomography (PET), is increasingly used as biomarker to predict and assess treatment response in breast cancer. The number of biomarkers is expanding with specific tracers for tumour characteristics throughout the body and this information can be used to aid the decision-making process. These measurements include metabolic activity using [
    Language English
    Publishing date 2023-05-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2503443-1
    ISSN 1758-8359 ; 1758-8340
    ISSN (online) 1758-8359
    ISSN 1758-8340
    DOI 10.1177/17588359231170738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Correlation between Histopathological Prognostic Tumor Characteristics and [

    Boers, Jorianne / Eisses, Bertha / Zwager, Mieke C / van Geel, Jasper J L / Bensch, Frederike / de Vries, Erik F J / Hospers, Geke A P / Glaudemans, Andor W J M / Brouwers, Adrienne H / den Dekker, Martijn A M / Elias, Sjoerd G / Kuip, Evelien J M / van Herpen, Carla M L / Jager, Agnes / van der Veldt, Astrid A M / Oprea-Lager, Daniela E / de Vries, Elisabeth G E / van der Vegt, Bert / Menke-van der Houven van Oordt, Willemien C /
    Schröder, Carolina P

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 4

    Abstract: Background: In metastatic breast cancer (MBC), [: Patients and methods: Patients with non-rapidly progressive MBC of all subtypes prospectively underwent a baseline histological metastasis biopsy and [: Results: Of 200 patients, 188 had evaluable ... ...

    Abstract Background: In metastatic breast cancer (MBC), [
    Patients and methods: Patients with non-rapidly progressive MBC of all subtypes prospectively underwent a baseline histological metastasis biopsy and [
    Results: Of 200 patients, 188 had evaluable metastasis biopsies, and 182 of these contained tumor. HER2 positivity and Ki-67 ≥ 20% were correlated with higher [
    Conclusions: [
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14040416
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Clinical Validity of 16α-[

    van Geel, Jasper J L / Boers, Jorianne / Elias, Sjoerd G / Glaudemans, Andor W J M / de Vries, Erik F J / Hospers, Geke A P / van Kruchten, Michel / Kuip, Evelien J M / Jager, Agnes / Menke-van der Houven van Oordt, Willemien C / van der Vegt, Bert / de Vries, Elisabeth G E / Schröder, Carolina P

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2022  Volume 40, Issue 31, Page(s) 3642–3652

    Abstract: Purpose: Determining the estrogen receptor (ER) status is essential in metastatic breast cancer (MBC) management. Whole-body ER imaging with 16α-[: Methods: In a prospective multicenter trial, 200 patients with newly diagnosed MBC underwent extensive ...

    Abstract Purpose: Determining the estrogen receptor (ER) status is essential in metastatic breast cancer (MBC) management. Whole-body ER imaging with 16α-[
    Methods: In a prospective multicenter trial, 200 patients with newly diagnosed MBC underwent extensive workup including molecular imaging. For this subanalysis, ER expression in the biopsied metastasis was related to qualitative whole-body [
    Results: Whole-body [
    Conclusion: In this largest prospective series so far, we established the clinical validity of [
    MeSH term(s) Humans ; Female ; Estradiol ; Breast Neoplasms/pathology ; Receptors, Estrogen/metabolism ; Positron Emission Tomography Computed Tomography/methods ; Positron-Emission Tomography/methods ; Multicenter Studies as Topic
    Chemical Substances Estradiol (4TI98Z838E) ; Receptors, Estrogen
    Language English
    Publishing date 2022-05-18
    Publishing country United States
    Document type Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.00400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Article ; Online: PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial.

    Voorwerk, Leonie / Isaeva, Olga I / Horlings, Hugo M / Balduzzi, Sara / Chelushkin, Maksim / Bakker, Noor A M / Champanhet, Elisa / Garner, Hannah / Sikorska, Karolina / Loo, Claudette E / Kemper, Inge / Mandjes, Ingrid A M / de Maaker, Michiel / van Geel, Jasper J L / Boers, Jorianne / de Boer, Maaike / Salgado, Roberto / van Dongen, Marloes G J / Sonke, Gabe S /
    de Visser, Karin E / Schumacher, Ton N / Blank, Christian U / Wessels, Lodewyk F A / Jager, Agnes / Tjan-Heijnen, Vivianne C G / Schröder, Carolien P / Linn, Sabine C / Kok, Marleen

    Nature cancer

    2023  Volume 4, Issue 4, Page(s) 535–549

    Abstract: Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, synergy between immune ... ...

    Abstract Invasive lobular breast cancer (ILC) is the second most common histological breast cancer subtype, but ILC-specific trials are lacking. Translational research revealed an immune-related ILC subset, and in mouse ILC models, synergy between immune checkpoint blockade and platinum was observed. In the phase II GELATO trial ( NCT03147040 ), patients with metastatic ILC were treated with weekly carboplatin (area under the curve 1.5 mg ml
    MeSH term(s) Humans ; B7-H1 Antigen ; Carboplatin/therapeutic use ; Carcinoma, Lobular/drug therapy ; Carcinoma, Lobular/pathology ; Triple Negative Breast Neoplasms/drug therapy ; Triple Negative Breast Neoplasms/pathology
    Chemical Substances B7-H1 Antigen ; Carboplatin (BG3F62OND5)
    Language English
    Publishing date 2023-04-10
    Publishing country England
    Document type Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2662-1347
    ISSN (online) 2662-1347
    DOI 10.1038/s43018-023-00542-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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