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  1. Article: Skin manifestations of diabetes.

    Van Hattem, Simone / Bootsma, Aart H / Thio, H Bing

    Cleveland Clinic journal of medicine

    2008  Volume 75, Issue 11, Page(s) 772, 774, 776–7 passim

    Abstract: Diabetes mellitus can be complicated by a variety of cutaneous manifestations. Good metabolic control may prevent some of these manifestations and may support cure. Unfortunately, most glucose-lowering drugs also have cutaneous side effects. It is ... ...

    Abstract Diabetes mellitus can be complicated by a variety of cutaneous manifestations. Good metabolic control may prevent some of these manifestations and may support cure. Unfortunately, most glucose-lowering drugs also have cutaneous side effects. It is important to be able to recognize these signs and symptoms and to either treat them appropriately or refer the patient to a dermatologist or diabetologist.
    MeSH term(s) Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/physiopathology ; Humans ; Hypoglycemic Agents/adverse effects ; Insulin/analogs & derivatives ; Risk Factors ; Skin Diseases/chemically induced ; Skin Diseases/etiology ; Skin Diseases/physiopathology
    Chemical Substances Hypoglycemic Agents ; Insulin
    Language English
    Publishing date 2008-12-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639116-3
    ISSN 0891-1150
    ISSN 0891-1150
    DOI 10.3949/ccjm.75.11.772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Surgical treatment of sinuses by deroofing in hidradenitis suppurativa.

    van Hattem, Simone / Spoo, Julia R / Horváth, Barbara / Jonkman, Marcel F / Leeman, Fredrik W J

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2012  Volume 38, Issue 3, Page(s) 494–497

    MeSH term(s) Electrosurgery/methods ; Female ; Hidradenitis Suppurativa/surgery ; Humans ; Male ; Recurrence ; Treatment Outcome ; Wound Healing
    Language English
    Publishing date 2012-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1111/j.1524-4725.2011.02255.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Patient Perception of Imiquimod Treatment for Actinic Keratosis and Superficial Basal Cell Carcinoma in 202 Patients.

    Waalboer-Spuij, Rick / Holterhues, Cynthia / van Hattem, Simone / Schuttelaar, Marie Louise A / Gaastra, Menno T W / Kuijpers, Daniëlle I M / Hollestein, Loes M / Nijsten, Tamar E C

    Dermatology (Basel, Switzerland)

    2015  Volume 231, Issue 1, Page(s) 56–62

    Abstract: Objective: To document the impact on patient-reported outcomes and health-related quality of life (HRQoL) of treatment with imiquimod cream in patients with actinic keratosis (AK) and superficial basal cell carcinoma (sBCC).: Methods: This open-label, ...

    Abstract Objective: To document the impact on patient-reported outcomes and health-related quality of life (HRQoL) of treatment with imiquimod cream in patients with actinic keratosis (AK) and superficial basal cell carcinoma (sBCC).
    Methods: This open-label, multicenter study included AK and sBCC patients eligible for treatment with imiquimod 5% cream. HRQoL was measured by the Skindex-17 and the Skin Cancer Index (SCI) and treatment satisfaction by the Treatment Satisfaction Questionnaire for Medication.
    Results: 118 AK patients and 84 patients with sBCC were included. Low baseline HRQoL impairment was found on both questionnaires, which remained low after treatment, except for a small dip at the end of the application period.
    Conclusion: Imiquimod 5% cream treatment has no clinically relevant HRQoL impact in AK and sBCC patients according to the Skindex-17 and SCI. The effect of imiquimod treatment on HRQoL may be limited or these questionnaires do not fully capture relevant issues, such as fear of recurrence.
    MeSH term(s) Aged ; Aminoquinolines/adverse effects ; Aminoquinolines/therapeutic use ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Carcinoma, Basal Cell/drug therapy ; Female ; Humans ; Keratosis, Actinic/drug therapy ; Male ; Middle Aged ; Patient Satisfaction ; Quality of Life ; Skin Cream/therapeutic use ; Skin Neoplasms/drug therapy ; Surveys and Questionnaires
    Chemical Substances Aminoquinolines ; Antineoplastic Agents ; imiquimod (P1QW714R7M)
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000381420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Patient Perception of Imiquimod Treatment for Actinic Keratosis and Superficial Basal Cell Carcinoma in 202 Patients

    Waalboer-Spuij, Rick / Holterhues, Cynthia / van Hattem, Simone / Schuttelaar, Marie Louise A. / Gaastra, Menno T.W. / Kuijpers, Daniëlle I.M. / Hollestein, Loes M. / Nijsten, Tamar E.C.

    Dermatology

    2015  Volume 231, Issue 1, Page(s) 56–62

    Abstract: Objective: To document the impact on patient-reported outcomes and health-related quality of life (HRQoL) of treatment with imiquimod cream in patients with actinic keratosis (AK) and superficial basal cell carcinoma (sBCC). Methods: This open-label, ... ...

    Institution Dermatology Department, Erasmus MC University Medical Center, Rotterdam Dermatology Department, University Medical Center, Groningen Center Oosterwal, Alkmaar, and Dermatology Department, Amphia Hospital, Breda, The Netherlands
    Abstract Objective: To document the impact on patient-reported outcomes and health-related quality of life (HRQoL) of treatment with imiquimod cream in patients with actinic keratosis (AK) and superficial basal cell carcinoma (sBCC). Methods: This open-label, multicenter study included AK and sBCC patients eligible for treatment with imiquimod 5% cream. HRQoL was measured by the Skindex-17 and the Skin Cancer Index (SCI) and treatment satisfaction by the Treatment Satisfaction Questionnaire for Medication. Results: 118 AK patients and 84 patients with sBCC were included. Low baseline HRQoL impairment was found on both questionnaires, which remained low after treatment, except for a small dip at the end of the application period. Conclusion: Imiquimod 5% cream treatment has no clinically relevant HRQoL impact in AK and sBCC patients according to the Skindex-17 and SCI. The effect of imiquimod treatment on HRQoL may be limited or these questionnaires do not fully capture relevant issues, such as fear of recurrence.
    Keywords Health-related quality of life ; Treatment satisfaction ; Imiquimod ; Actinic keratosis ; Superficial basal cell carcinoma ; Patient-reported outcomes
    Language English
    Publishing date 2015-04-22
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 1099692-8
    ISSN 1421-9832 ; 1018-8665
    ISSN (online) 1421-9832
    ISSN 1018-8665
    DOI 10.1159/000381420
    Database Karger publisher's database

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