Article ; Online: Inhibition of pannexin-1 does not restore electrolyte balance in precystic Pkd1 knockout mice.
2024 Volume 12, Issue 7, Page(s) e15956
Abstract: Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease (ADPKD), which is characterized by the formation of fluid-filled cysts in the kidney. In a subset of ADPKD patients, reduced blood calcium ( ... ...
| Abstract | Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease (ADPKD), which is characterized by the formation of fluid-filled cysts in the kidney. In a subset of ADPKD patients, reduced blood calcium (Ca |
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| MeSH term(s) | Animals ; Humans ; Mice ; Adenosine Triphosphate/metabolism ; Kidney/metabolism ; Mice, Knockout ; Mutation ; Polycystic Kidney, Autosomal Dominant/metabolism ; TRPP Cation Channels/genetics ; TRPP Cation Channels/metabolism ; TRPP Cation Channels/pharmacology ; Water-Electrolyte Balance |
| Chemical Substances | Adenosine Triphosphate (8L70Q75FXE) ; TRPP Cation Channels ; polycystic kidney disease 1 protein ; Panx1 protein, mouse |
| Language | English |
| Publishing date | 2024-04-01 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2724325-4 |
| ISSN | 2051-817X ; 2051-817X |
| ISSN (online) | 2051-817X |
| ISSN | 2051-817X |
| DOI | 10.14814/phy2.15956 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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