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Article ; Online: Estimating occupational disease burden: a way forward.

Cherrie, John W / van Tongeren, Martie / Kromhout, Hans

2024

Abstract: Estimates of occupational disease burden provide important information on which effective policy and regulations can be developed. However, there is no direct way that these data can be obtained, and most burden estimates are derived by merging different ...

Abstract	Estimates of occupational disease burden provide important information on which effective policy and regulations can be developed. However, there is no direct way that these data can be obtained, and most burden estimates are derived by merging different data from diverse sources to synthesize estimates of the number of people made ill or who have died from workplace exposures. In recent years, several research groups have published estimates of occupational health burden at national or global scales; these are not always consistent. The World Health Organisation and the International Labour Organisation have taken on the task of producing occupational disease burden estimates for several workplace agents, which we assume are to be seen as the definitive global, regional, and national data. In this commentary, we critique the WHO/ILO approach for their estimates of the non-melanoma skin cancer burden from solar ultraviolet radiation and some of their results for hazardous particulates. We provide recommendations for researchers undertaking occupational burden estimates that they should report along with their data.
Language	English
Publishing date	2024-05-20
Publishing country	England
Document type	Journal Article
ZDB-ID	2885096-8
ISSN	2398-7316 ; 2398-7308
ISSN (online)	2398-7316
ISSN	2398-7308
DOI	10.1093/annweh/wxae040
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Article ; Online: The application of the mobile application for the assessment of cleaning workers' exposure to cleaning products: a pilot study.

Lee, Sewon / Povey, Andrew / van Tongeren, Martie

Annals of work exposures and health

2023 Volume 68, Issue 2, Page(s) 211–216

Abstract: Background: Cleaning product use has been associated with adverse respiratory health effects such as asthma in cleaning staff and healthcare workers. Research in health effects from cleaning products has largely depended upon collecting exposure ... ...

Abstract	Background: Cleaning product use has been associated with adverse respiratory health effects such as asthma in cleaning staff and healthcare workers. Research in health effects from cleaning products has largely depended upon collecting exposure information by questionnaires which has limitations such as recall bias and underestimation of exposure. The aim of this study was to develop a Cleaning and Hazardous Products Exposure Logging (CHaPEL) app with a barcode scanner and to test the feasibility of this app with university cleaners. Methods: The CHaPEL app was developed to collect information on demographics, individual product information, and exposure information. It also included an ease-of-use survey. A pilot study with university cleaning workers was undertaken in which cleaning workers scanned each product after use and answered the survey. Respiratory hazards of cleaning substances in the scanned cleaning products were screened by safety data sheets, a Quantitative Structure-Activity Relationship model and an asthmagen list established by an expert group in the US. Results: Eighteen university cleaners participated in this study over a period of 5 weeks. In total, 77 survey responses and 6 cleaning products were collected and all reported that using the app was easy. The most frequently used product was a multi-surface cleaner followed by a disinfectant. Out of 14 substances in cleaning products, ethanolamine and Alkyl (C12-16) dimethyl benzyl ammonium chloride were found as respiratory hazardous substances. Conclusion: The CHaPEL app is a user-friendly immediate way to successfully collect exposure information using the barcodes of cleaning products. This tool could be useful for future epidemiological studies focused on exposure assessment with less interruption to the workers.
MeSH term(s)	Humans ; Occupational Exposure/adverse effects ; Pilot Projects ; Mobile Applications ; Hazardous Substances ; Asthma
Chemical Substances	Hazardous Substances
Language	English
Publishing date	2023-12-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2885096-8
ISSN	2398-7316 ; 2398-7308
ISSN (online)	2398-7316
ISSN	2398-7308
DOI	10.1093/annweh/wxad082
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Article ; Online: Letter to the editor.

Kromhout, Hans / Cherrie, John W / van Tongeren, Martie

Environment international

2023 Volume 179, Page(s) 108107

Language	English
Publishing date	2023-08-28
Publishing country	Netherlands
Document type	Letter
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2023.108107
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Article: Are platelet volume indices of clinical use in COVID-19? A systematic review.

Daniels, Sarah / Wei, Hua / van Tongeren, Martie / Denning, David W

Frontiers in cardiovascular medicine

2022 Volume 9, Page(s) 1031092

Abstract: Background: The incidence of thrombotic complications is high in COVID-19 patients with severe disease. As key regulators of thrombus formation, platelets likely play a crucial role as mediators of severe acute respiratory syndrome coronavirus 2 ... ...

Abstract	Background: The incidence of thrombotic complications is high in COVID-19 patients with severe disease. As key regulators of thrombus formation, platelets likely play a crucial role as mediators of severe acute respiratory syndrome coronavirus 2 associated pathogenesis. Studies have reported that parameters reflecting platelet size, known as platelet volume indices (PVI), are raised in patients with thrombosis and can predict poor outcomes. This systematic review evaluates the potential for PVI to be used as a predictor of COVID-19 morbidity and mortality. Methods: English and Chinese databases were searched electronically to identify studies reporting data on mean platelet volume, platelet distribution width or platelet-large cell ratio in COVID-19 patients. Included articles underwent a quality rating and descriptive narrative analysis. Results: Thirty-two studies were included in the systematic review. The results show a general trend for PVI to be raised in severe COVID-19 patients and non-survivors, with 14 studies reporting significant differences of baseline PVI between severe and mild disease. Nonetheless, longitudinal studies showed varying PVI trends over the course of the disease and evidence for PVI to be associated with disease progression was limited. The quality rating of 12 studies was poor, 16 were rated fair and four were good. Most studies were retrospective in design, used small study populations and did not consider confounding factors that influence platelet volume. Studies also contained technical flaws in PVI measurement, limiting the reliability of the results. Conclusion: The evidence on the clinical usefulness of PVI is greatly limited by the lack of prospective evaluation, together with technical problems in measuring PVI. Carefully designed prospective studies are warranted. Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=304305, identifier CRD42022304305.
Language	English
Publishing date	2022-10-18
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2022.1031092
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Article ; Online: A deep dive into selected work sectors during the COVID-19 pandemic and the "living with COVID" phase: understanding similarities and differences in practice, perceptions, and preparedness.

Coleman, Anna / Canham, Rebecca / Clabon, Katie / Hosseini, Paniz / Johnson, Sheena / van Tongeren, Martie

Annals of work exposures and health

2023 Volume 67, Issue 9, Page(s) 1099–1110

Abstract: Objectives: When it comes to controlling workplace transmission of SARS-CoV-2, the virus that causes COVID-19, different workplaces and industrial sectors face different challenges, both in terms of likely transmission routes and which control measures ... ...

Abstract	Objectives: When it comes to controlling workplace transmission of SARS-CoV-2, the virus that causes COVID-19, different workplaces and industrial sectors face different challenges, both in terms of likely transmission routes and which control measures can be practically, economically, and effectively implemented. This article considers a large body of research in the United Kingdom across different work sectors and time points during the COVID-19 pandemic to better understand mitigation measures, challenges to mitigating the risk of SARS-COV-2 transmission, knowledge gaps, and barriers and enablers to control viral transmission. Methods: Data is drawn from 2 phases of research. Phase 1 gathered data from an interactive workshop (April 2022) where PROTECT researchers working across 8 work sectors shared knowledge and expertise from research conducted between 2020 and 2022. Phase 2 revisited 6 of these sectors to explore participants' views on the "living with COVID" phase of the pandemic (February-October 2022) through qualitative interviews. Results: Our findings emphasise the importance of considering the characteristics of each work sector (and their sub-sectors), relative to the physical workplace and workforce, the ways organisations operate, and how they interact with the public. Study findings show that participant's views and organisational practices changed quickly and significantly over the course of the pandemic. Most participants initially perceived that the majority of risk mitigations would remain in place for the foreseeable future. However, following the change in Government Guidance towards "living with COVID", most mitigation measures were quickly removed and it had become necessary for sectors/organisations to restore normal operations, thereby treating the COVID-19 virus like any other illness, while remaining prepared for future health emergencies that may arise. Conclusion: We suggest that national policy makers and organisational leaders remain mindful of the lessons learned and knowledge gained at all levels (national, regional, local, organisational, and individual) during the COVID-19 pandemic. We make recommendations in support of recovery as sectors/organisations continue "living with COVID" and other respiratory diseases; balanced with longer term planning for the next public health crisis.
MeSH term(s)	Humans ; COVID-19 ; Pandemics/prevention & control ; SARS-CoV-2 ; Occupational Exposure ; Workplace
Language	English
Publishing date	2023-09-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2885096-8
ISSN	2398-7316 ; 2398-7308
ISSN (online)	2398-7316
ISSN	2398-7308
DOI	10.1093/annweh/wxad053
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Article ; Online: how these findings canPublic transport: lessons learned by the sector through the COVID-19 pandemic.

Gartland, Nicola / Coleman, Anna / Farrell, Bernadine / Fishwick, David / Johnson, Sheena / van Tongeren, Martie

BMC public health

2023 Volume 23, Issue 1, Page(s) 1904

Abstract: Background: The COVID-19 pandemic had a significant impact on the operations and functionality of the public transport sector in the UK. This paper reflects on the experience of this sector through the pandemic period, and considers recommendations for ... ...

Abstract	Background: The COVID-19 pandemic had a significant impact on the operations and functionality of the public transport sector in the UK. This paper reflects on the experience of this sector through the pandemic period, and considers recommendations for any future mitigations required for either new COVID-19 waves or a different public health emergency. Methods: Semi-structured interviews were carried out with public transport experts, organisational leaders, workers and passengers in two phases: Phase 1 from January to May 2021, and Phase 2 from December 2021 to February 2022. Interviews were analysed thematically. Results: Using the 'What? So What? Now What?' reflective model, ideas are drawn out to describe (a) what changes occurred, (b) what effects these changes had on service provision as well as perceptions of risk and mitigation and (c) what lessons have been learned and how these findings can feed into pandemic preparedness for the future. Respondent reflections focussed on the importance of communication, leadership, and maintaining compliance. Conclusions: The wealth of experience gained through the COVID-19 pandemic in the public transport sector is extremely valuable. Through reflection on this experience, specific recommendations are made relating to these factors, covering: maintaining links across industry, access to information and data, understanding of mitigation effectiveness, improving messaging, challenges of behavioural mitigations, and clear lines of accountability. The recommendations made on the basis of this reflective process will help to improve public health strategy within the public transport sector.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics/prevention & control ; Communication ; Industry ; Leadership
Language	English
Publishing date	2023-10-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-16062-3
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Article ; Online: X2018-The 9th International Conference on the Science of Exposure Assessment.

Jones, Kate / van Tongeren, Martie

Annals of work exposures and health

2019 Volume 63, Issue 6, Page(s) 605–607

Language	English
Publishing date	2019-06-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2885096-8
ISSN	2398-7316 ; 2398-7308
ISSN (online)	2398-7316
ISSN	2398-7308
DOI	10.1093/annweh/wxz050
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Article ; Online: Occupation and SARS-CoV-2 infection risk among workers during the first pandemic wave in Germany: potential for bias.

Martie van Tongeren, Martie van Tongeren / Rhodes, Sarah / Pearce, Neil

Scandinavian journal of work, environment & health

2022 Volume 48, Issue 7, Page(s) 586–587

MeSH term(s)	Adult ; BNT162 Vaccine ; COVID-19/epidemiology ; Germany/epidemiology ; Humans ; Occupations ; Pandemics ; Prospective Studies ; RNA, Viral ; SARS-CoV-2
Chemical Substances	RNA, Viral ; BNT162 Vaccine (N38TVC63NU)
Language	English
Publishing date	2022-08-08
Publishing country	Finland
Document type	Letter ; Comment
ZDB-ID	191563-0
ISSN	1795-990X ; 0355-3140
ISSN (online)	1795-990X
ISSN	0355-3140
DOI	10.5271/sjweh.4052
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Article ; Online: The impact of occupational exposures on infection rates during the COVID-19 pandemic: a test-negative design study with register data of 207 034 Dutch workers.

Eekhout, Iris / van Tongeren, Martie / Pearce, Neil / Oude Hengel, Karen M

Scandinavian journal of work, environment & health

2023 Volume 49, Issue 4, Page(s) 259–270

Abstract: Objective: This study aimed to investigate the effects of occupational exposures on the risk of a positive COVID-19 test, and whether this differed across pandemic waves.: Methods: Data from 207 034 workers from The Netherlands with test data on ... ...

Abstract	Objective: This study aimed to investigate the effects of occupational exposures on the risk of a positive COVID-19 test, and whether this differed across pandemic waves. Methods: Data from 207 034 workers from The Netherlands with test data on COVID-19 from June 2020 until August 2021 were available. Occupational exposure was estimated by using the eight dimensions of a COVID-19 job exposure matrix (JEM). Personal characteristics, household composition and residence area were derived from Statistics Netherlands. A test-negative design was applied in which the risk of a positive test was analyzed in a conditional logit model. Results: All eight dimensions of occupational exposure included in the JEM increased the odds of a positive test for the entire study period and three pandemic waves [OR ranging from 1.09, (95% confidence interval (CI) 1.02-1.17) to 1.77 (95% CI 1.61-1.96)]. Adjusting for a previous positive test and other covariates strongly reduced the odds to be infected, but most dimensions remained at elevated risk. Fully adjusted models showed that contaminated work spaces and face covering were mostly relevant in the first two pandemic waves, whereas income insecurity showed higher odds in the third wave. Several occupations have a higher predicted value for a positive COVID-19 test, with variation over time. Discussion Occupational exposures are associated with a higher risk of a positive test, but variations over time exist in occupations with the highest risks. These findings provide insights for interventions among workers for future pandemic waves of COVID-19 or other respiratory epidemics.
MeSH term(s)	Humans ; COVID-19 ; Pandemics ; Occupational Exposure ; Occupations ; Netherlands
Language	English
Publishing date	2023-03-13
Publishing country	Finland
Document type	Journal Article
ZDB-ID	191563-0
ISSN	1795-990X ; 0355-3140
ISSN (online)	1795-990X
ISSN	0355-3140
DOI	10.5271/sjweh.4086
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Article ; Online: Irritant asthma and work: cases from the UK SWORD reporting scheme from 1999 to 2018.

Fishwick, David / Carder, Melanie / Iskandar, Ireny / Fishwick, Beth Charlotte / van Tongeren, Martie

Occupational and environmental medicine

2023 Volume 80, Issue 10, Page(s) 553–557

Abstract: Background: Acute irritant asthma is a preventable health consequence of a workplace exposure and has a number of adverse outcomes. While cases and case series are reported, little is known about the causes and incidence of this condition over prolonged ...

Abstract	Background: Acute irritant asthma is a preventable health consequence of a workplace exposure and has a number of adverse outcomes. While cases and case series are reported, little is known about the causes and incidence of this condition over prolonged periods of time. Aims: We aimed to estimate the reported incidence of irritant asthma referred to a national reporting scheme, and how this has changed over time. Methods: Cases of irritant asthma reported to SWORD, the UK-based Surveillance of Work-related Occupational Respiratory Diseases scheme, were grouped into four 5-year time periods from 1999 onwards. Likely causative exposures, job, work sector and incidence rates were analysed over time. Results: 307 actual cases equated to 1066 estimated cases; actual cases had a mean age of 46 years (SD 17.8); 70.7% were male. The annual incidence fell from 1.98 per million employed in the first 5-year period, to 0.56 in the most recent. Eleven occupational codes were associated with six or more attributed cases, and between them accounted for 38% of all cases. Thirteen exposure categories were associated with five or more cases. These were formaldehyde (n=5), cutting oils and coolants (n=6), isocyanates (n=6), pesticides and herbicides (n=6), welding fumes (n=7), paints (n=7), solder and colophony (n=7), solvents (n=9), fuel oil, diesel and ill-defined fumes (n=10), chlorine and hypochlorites (n=15), acids (n=23), smoke (n=25) and cleaning products and sterilising agents (n=39). Conclusions: While the incidence of irritant asthma may have fallen, cases are persistently attributed to well-described causes. A persistence of cases attributed to cleaning agents was seen.
MeSH term(s)	Humans ; Male ; Middle Aged ; Female ; Irritants/adverse effects ; Occupational Diseases/epidemiology ; Occupational Diseases/etiology ; Asthma/epidemiology ; Asthma/etiology ; Incidence ; United Kingdom/epidemiology ; Occupational Exposure/adverse effects
Chemical Substances	Irritants
Language	English
Publishing date	2023-09-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1180733-7
ISSN	1470-7926 ; 1351-0711
ISSN (online)	1470-7926
ISSN	1351-0711
DOI	10.1136/oemed-2023-108884
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