Article ; Online: Shape-defined solid micro-objects from poly(d,l-lactic acid) as cell-supportive counterparts in bottom-up tissue engineering.
Materials today. Bio
2019 Volume 4, Page(s) 100025
Abstract: In bottom-up tissue engineering, small modular units of cells and biomaterials are assembled toward larger and more complex ones. In conjunction with a new implementation of this approach, a novel method to fabricate microscale objects from biopolymers ... ...
| Abstract | In bottom-up tissue engineering, small modular units of cells and biomaterials are assembled toward larger and more complex ones. In conjunction with a new implementation of this approach, a novel method to fabricate microscale objects from biopolymers by thermal imprinting on water-soluble sacrificial layers is presented. By this means, geometrically well-defined objects could be obtained without involving toxic agents in the form of photoinitiators. The micro-objects were used as cell-adhesive substrates and cell spacers in engineered tissues created by cell-guided assembly of the objects. Such constructs can be applied both for |
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| Language | English |
| Publishing date | 2019-08-20 |
| Publishing country | England |
| Document type | Journal Article |
| ISSN | 2590-0064 |
| ISSN (online) | 2590-0064 |
| DOI | 10.1016/j.mtbio.2019.100025 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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