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  1. Article: Epidemiology of unexplained chronic cough in adults: a population-based study.

    Arinze, Johnmary T / van der Veer, Tjeerd / Bos, Daniel / Stricker, Bruno / Verhamme, Katia M C / Brusselle, Guy

    ERJ open research

    2023  Volume 9, Issue 3

    Abstract: Unexplained chronic cough accounts for a significant proportion of chronic cough cases in adults, and its persistent phenotype shows female preponderance that is demographically similar to individuals with cough ... ...

    Abstract Unexplained chronic cough accounts for a significant proportion of chronic cough cases in adults, and its persistent phenotype shows female preponderance that is demographically similar to individuals with cough hypersensitivity
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00739-2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Structural Lung Disease and Clinical Phenotype in Bronchiectasis Patients: The EMBARC CT Study.

    Pieters, Angelina L P / van der Veer, Tjeerd / Meerburg, Jennifer J / Andrinopoulou, Eleni-Rosalina / Vd Eerden, Menno M / Ciet, Pierluigi / Aliberti, Stefano / Burgel, Pierre-Regis / Crichton, Megan L / Shoemark, Amelia / Goeminne, Pieter C / Shteinberg, Michal / Loebinger, Michael R / Haworth, Charles S / Blasi, Francesco / Tiddens, Harm Awm / Caudri, Daan / Chalmers, James D

    American journal of respiratory and critical care medicine

    2024  

    Abstract: Rationale: Chest computed tomography -scans (CTs) are essential to diagnose and monitor bronchiectasis (BE). To date, little quantitative data is available about the nature and extent of structural lung abnormalities (SLA) on CTs of BE patients.: ... ...

    Abstract Rationale: Chest computed tomography -scans (CTs) are essential to diagnose and monitor bronchiectasis (BE). To date, little quantitative data is available about the nature and extent of structural lung abnormalities (SLA) on CTs of BE patients.
    Objectives: to investigate SLA on CTs of patients with bronchiectasis and the relationship of SLAs to clinical features using the European Bronchiectasis Registry (EMBARC) Methods: CTs from BE patients included in the EMBARC registry were analyzed using the validated Bronchiectasis Scoring Technique for CT (BEST-CT). BEST-CT subscores are expressed as % of total lung volume. Scored items are: atelectasis/consolidation (%ATCON), bronchiectasis with and without mucus plugging (%BEMP, %BEwMP), airway wall thickening (%AWT), mucus plugging (%MP), ground-glass opacities (%GGO), bullae (%BUL), airways and parenchyma (%A,%P). Four composite scores were calculated: Total BE (%TBE=%BEMP+%BEwMP), total MP (%TMP=%BEMP+%MP), total inflammatory changes (%TinF=%ATCON+%BEMP+%MP+%GGO) and total disease (%DIS= all but %A & %P). Measurments and Main Results: CTs of 524 BE patients were analyzed. Mean (range) of subscores were: %TBE 4.6 (2.3-7.7), %TMP 4.2 (1.2-8.1), %TinF 8.3 (3.5-16.7) and %DIS 14.9 (9.1-25.9). BE associated with primary ciliary dyskinesia was associated with more SLA, while COPD was associated with less SLA. Lower FEV1, longer disease duration, Pseudomonas aeruginosa and NTM infection, and severe exacerbations were all independently associated with worse SLA.
    Conclusion: Patients with bronchiectasis have highly heterogeneous type and extent of structural lung abnormalities. Strong relationships between radiological disease and clinical features suggest CT analysis may be a useful tool for clinical phenotyping.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202311-2109OC
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The effect of beclomethasone-formoterol

    van der Veer, Tjeerd / de Koning Gans, Johanna Margaretha / Braunstahl, Gerrit J / Pieters, Angelina L P / van den Berg, Johanna M W / Hoek, Rogier A S / Kamphuis, Lieke S J / Bakker, Marleen / Dubois, Alain V F / Aerts, Joachim G J V / van der Eerden, Menno M

    The European respiratory journal

    2023  Volume 61, Issue 6

    MeSH term(s) Humans ; Formoterol Fumarate/therapeutic use ; Beclomethasone/therapeutic use ; Cough/drug therapy ; Asthma/drug therapy ; Bronchiectasis/complications ; Bronchiectasis/drug therapy ; Double-Blind Method ; Administration, Inhalation
    Chemical Substances Formoterol Fumarate (W34SHF8J2K) ; Beclomethasone (KGZ1SLC28Z)
    Language English
    Publishing date 2023-06-29
    Publishing country England
    Document type Randomized Controlled Trial ; Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.00186-2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Reduced exacerbation frequency and prednisone dose in patients with ABPA and asthma treated with dupilumab.

    van der Veer, Tjeerd / Dallinga, Marloes A / van der Valk, Johanna P M / Kappen, Jasper H / In 't Veen, Johannes C C M / van der Eerden, Menno M / Braunstahl, Gert-Jan

    Clinical and translational allergy

    2021  Volume 11, Issue 10, Page(s) e12081

    Language English
    Publishing date 2021-12-28
    Publishing country England
    Document type Letter
    ZDB-ID 2630865-4
    ISSN 2045-7022
    ISSN 2045-7022
    DOI 10.1002/clt2.12081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Do-not-intubate status and COVID-19 mortality in patients admitted to Dutch non-ICU wards.

    van der Veer, Tjeerd / van der Sar-van der Brugge, Simone / Paats, Marthe S / van Nood, Els / de Backer, Ingrid C / Aerts, Joachim G J V / van der Eerden, Menno M

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2021  Volume 40, Issue 10, Page(s) 2207–2209

    Abstract: Mortality from COVID-19 has been particularly high in elderly patients on mechanical ventilation. Treatment outcomes for patients with do-not-intubate (DNI) status are unknown. One hundred patients admitted to the non-ICU ward during the "first wave" ... ...

    Abstract Mortality from COVID-19 has been particularly high in elderly patients on mechanical ventilation. Treatment outcomes for patients with do-not-intubate (DNI) status are unknown. One hundred patients admitted to the non-ICU ward during the "first wave" were retrospectively analyzed. Mortality rate was 49% in patients with a DNI order. This subgroup was characterized by significantly higher age, more comorbidity, and care dependency. Mortality among DNI patients was three times higher than other patients, but not higher than some of the published mortality rates for elderly mechanically ventilated patients. Advanced care planning is essential in COVID-19 to assist patient autonomy and prevent non-beneficial medical interventions.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/mortality ; COVID-19/therapy ; Hospital Mortality ; Humans ; Intensive Care Units/statistics & numerical data ; Intubation ; Male ; Middle Aged ; Netherlands ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2021-03-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-021-04223-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Levamisole-contaminated cocaine: a hairy affair.

    van der Veer, Tjeerd / Pennings, Ed / Tervaert, J W Cohen / Korswagen, Lindy-Anne

    BMJ case reports

    2015  Volume 2015

    Abstract: Levamisole-contaminated cocaine can induce severe systemic vasculitis. The diagnosis can be challenging, especially when substance abuse is uncertain. We present the case of a 42-year-old woman suffering from vasculitis due to levamisole-contaminated ... ...

    Abstract Levamisole-contaminated cocaine can induce severe systemic vasculitis. The diagnosis can be challenging, especially when substance abuse is uncertain. We present the case of a 42-year-old woman suffering from vasculitis due to levamisole-contaminated cocaine, who persistently denied substance abuse. Symptoms included ulcerating skin lesions, arthralgia and myalgia, and the occurrence of an ileal intussusception. The definitive diagnosis was made using hair testing for toxins. She recovered through cocaine abstinence, but re-exposure resulted in a severe relapse with glomerulonephritis. Importantly, at time of the relapse, the patient became positive for both myeloperoxidase-antineutrophil cytoplasmic antibody (ANCA) and proteinase 3-ANCA. Cocaine-levamisole-induced vasculitis poses a great clinical challenge. The proper diagnostic strategy and therapy is still controversial. We highlight our diagnostic and therapeutic considerations, including hair testing for definitive proof of exposure.
    MeSH term(s) Adjuvants, Immunologic/adverse effects ; Adjuvants, Immunologic/metabolism ; Adult ; Antibodies, Antineutrophil Cytoplasmic/metabolism ; Cocaine/administration & dosage ; Cocaine-Related Disorders/complications ; Drug Contamination ; Female ; Glomerulonephritis/chemically induced ; Hair/metabolism ; Humans ; Levamisole/adverse effects ; Levamisole/metabolism ; Peroxidase/metabolism ; Recurrence ; Vasculitis/chemically induced
    Chemical Substances Adjuvants, Immunologic ; Antibodies, Antineutrophil Cytoplasmic ; Levamisole (2880D3468G) ; Peroxidase (EC 1.11.1.7) ; Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2015-08-26
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-210970
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A 79-Year-Old Woman With Dyspnea and Hypoxemia That Worsened in an Upright Position.

    van der Veer, Tjeerd / In 't Veen, Johannes C C M / den Dekker, Wijnand K / Miedema, Jelle

    Chest

    2017  Volume 152, Issue 6, Page(s) e139–e142

    Abstract: Case presentation: A 79-year-old woman presented to the ED with complaints of gradually worsening exertional dyspnea, dizziness, and chest discomfort. For several weeks she had not been able to perform light household work. The patient's medical history ...

    Abstract Case presentation: A 79-year-old woman presented to the ED with complaints of gradually worsening exertional dyspnea, dizziness, and chest discomfort. For several weeks she had not been able to perform light household work. The patient's medical history mentioned pulmonary embolism following immobilization (2012), several fractures after trauma, an ischemic cerebral vascular accident (2014), and curative treatment for breast cancer (1995). Her current medication included esomeprazole, clopidogrel, simvastatin, calcium/vitamin D, amitriptyline, and acetaminophen.
    MeSH term(s) Abnormalities, Multiple ; Aged ; Aortic Aneurysm, Thoracic/complications ; Aortic Aneurysm, Thoracic/diagnosis ; Cardiac Catheterization ; Cardiac Surgical Procedures/methods ; Diagnosis, Differential ; Dyspnea/diagnosis ; Dyspnea/etiology ; Echocardiography ; Female ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/diagnosis ; Foramen Ovale, Patent/surgery ; Humans ; Hypoxia/diagnosis ; Hypoxia/etiology ; Septal Occluder Device ; Syndrome ; Tomography, X-Ray Computed
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2017.07.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Health behaviors, care needs and attitudes towards self-prescription: a cross-sectional survey among Dutch medical students.

    Van der Veer, Tjeerd / Frings-Dresen, Monique H W / Sluiter, Judith K

    PloS one

    2011  Volume 6, Issue 11, Page(s) e28038

    Abstract: Purpose: There is a growing awareness of the potent ways in which the wellbeing of physicians impacts the health of their patients. The purpose of this study was to investigate the health behaviors, care needs and attitudes towards self-prescription of ... ...

    Abstract Purpose: There is a growing awareness of the potent ways in which the wellbeing of physicians impacts the health of their patients. The purpose of this study was to investigate the health behaviors, care needs and attitudes towards self-prescription of Dutch medical students, and any differences between junior preclinical and senior clinically active students.
    Methods: All students (n = 2695) of a major Dutch medical school were invited for an online survey. Physical activity, eating habits, alcohol consumption, smoking, Body Mass Index, substance use and amount of sleep per night were inquired, as well as their need for different forms of care and their attitude towards self-prescription.
    Results: Data of 902 students were used. Physical activity levels (90% sufficient) and smoking prevalence (94% non-smokers) were satisfying. Healthy eating habits (51% insufficient) and alcohol consumption (46% excessive) were worrying. Body Mass Indexes were acceptable (20% unhealthy). We found no significant differences in health behaviors between preclinical and clinically active students. Care needs were significantly lower among clinically active students. (p<0.05) Student acceptance of self-prescription was significantly higher among clinically active students. (p<0.001)
    Conclusions: Unhealthy behaviors are prevalent among medical students, but are no more prevalent during the clinical study phase. The need for specific forms of care appears lower with study progression. This could be worrying as the acceptance of self-care and self-prescription is higher among senior clinical students. Medical faculties need to address students' unhealthy behaviors and meet their care needs for the benefit of both the future physicians as well as their patients.
    MeSH term(s) Cross-Sectional Studies ; Demography ; Drug Prescriptions/statistics & numerical data ; Female ; Habits ; Health Behavior ; Health Knowledge, Attitudes, Practice ; Health Services Needs and Demand/statistics & numerical data ; Humans ; Male ; Netherlands/epidemiology ; Self Medication ; Students, Medical/classification ; Students, Medical/statistics & numerical data
    Language English
    Publishing date 2011-11-21
    Publishing country United States
    Document type Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0028038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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