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  1. Buch: Plant chemical biology

    Audenaert, Dominique / Overvoorde, Paul

    2014  

    Abstract: The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to ... ...

    Verfasserangabe edited by Dominique Audenaert, Paul Overvoorde
    Abstract "The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to identify small molecules that can be used to identify the targets of currently used herbicides, as well as to develop new herbicides or plant growth regulators. The author introduces researchers and graduate students to the chemical biology toolbox required to perform successful chemical biology studies. The text also examines several chemical biology studies to show how they allowed novel insights into the field of plant physiology and plant cellular processes"--Provided by publisher.
    Mesh-Begriff(e) Plants/chemistry ; Plant Physiological Phenomena ; Biochemical Phenomena
    Sprache Englisch
    Umfang xi, 299 pages :, illustrations
    Dokumenttyp Buch
    ISBN 9780470946695 ; 0470946695
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  2. Buch: Plant chemical biology

    Audenaert, Dominique / Overvoorde, Paul

    2014  

    Abstract: The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to ... ...

    Verfasserangabe ed. by Dominique Audenaert; Paul Overvoorde
    Abstract "The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to identify small molecules that can be used to identify the targets of currently used herbicides, as well as to develop new herbicides or plant growth regulators. The author introduces researchers and graduate students to the chemical biology toolbox required to perform successful chemical biology studies. The text also examines several chemical biology studies to show how they allowed novel insights into the field of plant physiology and plant cellular processes"--Provided by publisher
    Mesh-Begriff(e) Biochemical Phenomena ; Plant Physiological Phenomena ; Plants/chemistry
    Schlagwörter Botanical chemistry
    Sprache Englisch
    Umfang XI, 299 S., [4 Bl.], Ill., graph. Darst.
    Verlag Wiley
    Erscheinungsort Hoboken, NJ
    Dokumenttyp Buch
    Anmerkung Literaturangaben
    ISBN 9780470946695 ; 0470946695
    Datenquelle Leibniz-Institut für Pflanzenbiochemie

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  3. Buch: Plant chemical biology

    Audenaert, Dominique / Overvoorde, Paul

    2014  

    Abstract: The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to ... ...

    Verfasserangabe ed. by Dominique Audenaert; Paul Overvoorde
    Abstract "The application of plant chemical biology is currently limited to specialized subfields of plant research. By examining how chemical biology can be applied to study plant biology, Plant Chemical Biology illustrates how chemical biology is a means to identify small molecules that can be used to identify the targets of currently used herbicides, as well as to develop new herbicides or plant growth regulators. The author introduces researchers and graduate students to the chemical biology toolbox required to perform successful chemical biology studies. The text also examines several chemical biology studies to show how they allowed novel insights into the field of plant physiology and plant cellular processes"--Provided by publisher
    Mesh-Begriff(e) Biochemical Phenomena ; Plant Physiological Phenomena ; Plants/chemistry
    Schlagwörter Botanical chemistry
    Sprache Englisch
    Umfang XI, 299 S., Ill., graph. Darst.
    Verlag Wiley
    Erscheinungsort Hoboken, NJ
    Dokumenttyp Buch
    Anmerkung Literaturangaben
    ISBN 9780470946695 ; 0470946695
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  4. Artikel ; Online: Auxin control of root development.

    Overvoorde, Paul / Fukaki, Hidehiro / Beeckman, Tom

    Cold Spring Harbor perspectives in biology

    2010  Band 2, Heft 6, Seite(n) a001537

    Abstract: A plant's roots system determines both the capacity of a sessile organism to acquire nutrients and water, as well as providing a means to monitor the soil for a range of environmental conditions. Since auxins were first described, there has been a tight ... ...

    Abstract A plant's roots system determines both the capacity of a sessile organism to acquire nutrients and water, as well as providing a means to monitor the soil for a range of environmental conditions. Since auxins were first described, there has been a tight connection between this class of hormones and root development. Here we review some of the latest genetic, molecular, and cellular experiments that demonstrate the importance of generating and maintaining auxin gradients during root development. Refinements in the ability to monitor and measure auxin levels in root cells coupled with advances in our understanding of the sources of auxin that contribute to these pools represent important contributions to our understanding of how this class of hormones participates in the control of root development. In addition, we review the role of identified molecular components that convert auxin gradients into local differentiation events, which ultimately defines the root architecture.
    Mesh-Begriff(e) Indoleacetic Acids/metabolism ; Plant Development ; Plant Roots/growth & development ; Plant Shoots/metabolism ; Plants/metabolism ; Signal Transduction/physiology
    Chemische Substanzen Indoleacetic Acids
    Sprache Englisch
    Erscheinungsdatum 2010-04-28
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
    ISSN 1943-0264
    ISSN (online) 1943-0264
    DOI 10.1101/cshperspect.a001537
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Development of a Biological Science Quantitative Reasoning Exam (BioSQuaRE).

    Stanhope, Liz / Ziegler, Laura / Haque, Tabassum / Le, Laura / Vinces, Marcelo / Davis, Gregory K / Zieffler, Andrew / Brodfuehrer, Peter / Preest, Marion / M Belitsky, Jason / Umbanhowar, Charles / Overvoorde, Paul J

    CBE life sciences education

    2017  Band 16, Heft 4

    Abstract: Multiple reports highlight the increasingly quantitative nature of biological research and the need to innovate means to ensure that students acquire quantitative skills. We present a tool to support such innovation. The Biological Science Quantitative ... ...

    Abstract Multiple reports highlight the increasingly quantitative nature of biological research and the need to innovate means to ensure that students acquire quantitative skills. We present a tool to support such innovation. The Biological Science Quantitative Reasoning Exam (BioSQuaRE) is an assessment instrument designed to measure the quantitative skills of undergraduate students within a biological context. The instrument was developed by an interdisciplinary team of educators and aligns with skills included in national reports such as
    Mesh-Begriff(e) Biological Science Disciplines/education ; Educational Measurement ; Models, Educational ; Reproducibility of Results
    Sprache Englisch
    Erscheinungsdatum 2017-11-28
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 2465176-X
    ISSN 1931-7913 ; 1931-7913
    ISSN (online) 1931-7913
    ISSN 1931-7913
    DOI 10.1187/cbe.16-10-0301
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: SAUR Inhibition of PP2C-D Phosphatases Activates Plasma Membrane H+-ATPases to Promote Cell Expansion in Arabidopsis.

    Spartz, Angela K / Ren, Hong / Park, Mee Yeon / Grandt, Kristin N / Lee, Sang Ho / Murphy, Angus S / Sussman, Michael R / Overvoorde, Paul J / Gray, William M

    The Plant cell

    2014  Band 26, Heft 5, Seite(n) 2129–2142

    Abstract: The plant hormone auxin promotes cell expansion. Forty years ago, the acid growth theory was proposed, whereby auxin promotes proton efflux to acidify the apoplast and facilitate the uptake of solutes and water to drive plant cell expansion. However, the ...

    Abstract The plant hormone auxin promotes cell expansion. Forty years ago, the acid growth theory was proposed, whereby auxin promotes proton efflux to acidify the apoplast and facilitate the uptake of solutes and water to drive plant cell expansion. However, the underlying molecular and genetic bases of this process remain unclear. We have previously shown that the SAUR19-24 subfamily of auxin-induced SMALL AUXIN UP-RNA (SAUR) genes promotes cell expansion. Here, we demonstrate that SAUR proteins provide a mechanistic link between auxin and plasma membrane H
    Sprache Englisch
    Erscheinungsdatum 2014-05-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1105/tpc.114.126037
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: The small molecule 2-furylacrylic acid inhibits auxin-mediated responses in Arabidopsis thaliana.

    Sungur, Can / Miller, Sarah / Bergholz, Johann / Hoye, Rebecca C / Brisbois, Ronald G / Overvoorde, Paul

    Plant & cell physiology

    2007  Band 48, Heft 12, Seite(n) 1693–1701

    Abstract: Auxins, typified by IAA, are a class of plant hormones involved in a wide array of processes including cell division, cell elongation, tissue patterning, phototropism, gravitropism and root development. Despite recent descriptions of the machinery ... ...

    Abstract Auxins, typified by IAA, are a class of plant hormones involved in a wide array of processes including cell division, cell elongation, tissue patterning, phototropism, gravitropism and root development. Despite recent descriptions of the machinery involved in auxin transport and perception, additional regulatory mechanisms and components remain to be identified and characterized. Chemical genetics has proven to be a valuable means by which to investigate the auxin response pathway in Arabidopsis thaliana. A screen for small molecules that block auxin signaling was performed previously, leading to the characterization of four compounds with this inhibitory activity. Here, we have synthesized various analogs of one of these molecules, compound A, a furyl acrylate ester of a thiadiazole heterocycle. The biological activity of these derivatives was initially assessed based on their ability to inhibit the auxin-inducible expression of the BA3-GUS reporter gene and indicated that the active portion of the molecule was 2-furylacrylic acid (2-FAA). In the micromolar range, 2-FAA attenuates the auxin-inducible expression of IAA5, fails to alter the interaction of IAA7/AXR2 with the SCF(TIR1) complex and inhibits both root and hypocotyl elongation of wild-type seedlings. Based on our structure-function analysis of compound A, we conclude that 2-furylacrylic acid is liberated by hydrolysis of an ester linkage. Identification of the cellular target of this molecule will add to our understanding of auxin-mediated events.
    Mesh-Begriff(e) Acrylates/chemistry ; Acrylates/metabolism ; Arabidopsis/physiology ; Hydrolysis ; Indoleacetic Acids/metabolism ; Structure-Activity Relationship
    Chemische Substanzen Acrylates ; Indoleacetic Acids ; acrylic acid (J94PBK7X8S)
    Sprache Englisch
    Erscheinungsdatum 2007-12
    Erscheinungsland Japan
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208907-5
    ISSN 1471-9053 ; 0032-0781
    ISSN (online) 1471-9053
    ISSN 0032-0781
    DOI 10.1093/pcp/pcm141
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: SAUR Inhibition of PP2C-D Phosphatases Activates Plasma Membrane H⁺-ATPases to Promote Cell Expansion in Arabidopsis

    Spartz, Angela K / Angus S. Murphy / Hong Ren / Kristin N. Grandt / Mee Yeon Park / Michael R. Sussman / Paul J. Overvoorde / Sang Ho Lee / William M. Gray

    plant cell. 2014 May, v. 26, no. 5

    2014  

    Abstract: This study demonstrates that SMALL AUXIN UP-RNA (SAUR) proteins negatively regulate PP2C-D family phosphatases to modulate the phosphorylation status and activity of plasma membrane H ⁺-ATPases to promote cell expansion. This work provides crucial ... ...

    Abstract This study demonstrates that SMALL AUXIN UP-RNA (SAUR) proteins negatively regulate PP2C-D family phosphatases to modulate the phosphorylation status and activity of plasma membrane H ⁺-ATPases to promote cell expansion. This work provides crucial molecular and genetic support for the decades-old acid growth theory of auxin-mediated cell expansion.
    Schlagwörter Arabidopsis ; auxins ; phosphorylation ; plasma membrane ; proteins
    Sprache Englisch
    Erscheinungsverlauf 2014-05
    Umfang p. 2129-2142.
    Erscheinungsort American Society of Plant Biologists
    Dokumenttyp Artikel
    ZDB-ID 623171-8
    ISSN 1532-298X ; 1040-4651
    ISSN (online) 1532-298X
    ISSN 1040-4651
    DOI 10.1105/tpc.114.126037
    Datenquelle NAL Katalog (AGRICOLA)

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  9. Artikel ; Online: The SAUR19 subfamily of SMALL AUXIN UP RNA genes promote cell expansion.

    Spartz, Angela K / Lee, Sang H / Wenger, Jonathan P / Gonzalez, Nathalie / Itoh, Hironori / Inzé, Dirk / Peer, Wendy A / Murphy, Angus S / Overvoorde, Paul J / Gray, William M

    The Plant journal : for cell and molecular biology

    2012  Band 70, Heft 6, Seite(n) 978–990

    Abstract: The plant hormone auxin controls numerous aspects of plant growth and development by regulating the expression of hundreds of genes. SMALL AUXIN UP RNA (SAUR) genes comprise the largest family of auxin-responsive genes, but their function is unknown. ... ...

    Abstract The plant hormone auxin controls numerous aspects of plant growth and development by regulating the expression of hundreds of genes. SMALL AUXIN UP RNA (SAUR) genes comprise the largest family of auxin-responsive genes, but their function is unknown. Although prior studies have correlated the expression of some SAUR genes with auxin-mediated cell expansion, genetic evidence implicating SAURs in cell expansion has not been reported. The Arabidopsis SAUR19, SAUR20, SAUR21, SAUR22, SAUR23, and SAUR24 (SAUR19-24) genes encode a subgroup of closely related SAUR proteins. We demonstrate that these SAUR proteins are highly unstable in Arabidopsis. However, the addition of an N-terminal GFP or epitope tag dramatically increases the stability of SAUR proteins. Expression of these stabilized SAUR fusion proteins in Arabidopsis confers numerous auxin-related phenotypes indicative of increased and/or unregulated cell expansion, including increased hypocotyl and leaf size, defective apical hook maintenance, and altered tropic responses. Furthermore, seedlings expressing an artificial microRNA targeting multiple members of the SAUR19-24 subfamily exhibit short hypocotyls and reduced leaf size. Together, these findings demonstrate that SAUR19-24 function as positive effectors of cell expansion. This regulation may be achieved through the modulation of auxin transport, as SAUR gain-of-function and loss-of-function seedlings exhibit increased and reduced basipetal indole-3-acetic acid transport, respectively. Consistent with this possibility, SAUR19-24 proteins predominantly localize to the plasma membrane.
    Mesh-Begriff(e) Arabidopsis/cytology ; Arabidopsis/genetics ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Cell Enlargement ; Gene Expression Regulation, Plant ; Indoleacetic Acids/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Multigene Family ; Plant Cells/metabolism ; Plant Growth Regulators/metabolism ; Protein Stability ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism
    Chemische Substanzen Arabidopsis Proteins ; Indoleacetic Acids ; Membrane Proteins ; Plant Growth Regulators ; Recombinant Fusion Proteins ; SAUR-AC1 protein, Arabidopsis
    Sprache Englisch
    Erscheinungsdatum 2012-03-31
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/j.1365-313X.2012.04946.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Student Attitudes Contribute to the Effectiveness of a Genomics CURE.

    Lopatto, David / Rosenwald, Anne G / Burgess, Rebecca C / Silver Key, Catherine / Van Stry, Melanie / Wawersik, Matthew / DiAngelo, Justin R / Hark, Amy T / Skerritt, Matthew / Allen, Anna K / Alvarez, Consuelo / Anderson, Sara / Arrigo, Cindy / Arsham, Andrew / Barnard, Daron / Bedard, James E J / Bose, Indrani / Braverman, John M / Burg, Martin G /
    Croonquist, Paula / Du, Chunguang / Dubowsky, Sondra / Eisler, Heather / Escobar, Matthew A / Foulk, Michael / Giarla, Thomas / Glaser, Rivka L / Goodman, Anya L / Gosser, Yuying / Haberman, Adam / Hauser, Charles / Hays, Shan / Howell, Carina E / Jemc, Jennifer / Jones, Christopher J / Kadlec, Lisa / Kagey, Jacob D / Keller, Kimberly L / Kennell, Jennifer / Kleinschmit, Adam J / Kleinschmit, Melissa / Kokan, Nighat P / Kopp, Olga Ruiz / Laakso, Meg M / Leatherman, Judith / Long, Lindsey J / Manier, Mollie / Martinez-Cruzado, Juan C / Matos, Luis F / McClellan, Amie Jo / McNeil, Gerard / Merkhofer, Evan / Mingo, Vida / Mistry, Hemlata / Mitchell, Elizabeth / Mortimer, Nathan T / Myka, Jennifer Leigh / Nagengast, Alexis / Overvoorde, Paul / Paetkau, Don / Paliulis, Leocadia / Parrish, Susan / Toering Peters, Stephanie / Preuss, Mary Lai / Price, James V / Pullen, Nicholas A / Reinke, Catherine / Revie, Dennis / Robic, Srebrenka / Roecklein-Canfield, Jennifer A / Rubin, Michael R / Sadikot, Takrima / Sanford, Jamie Siders / Santisteban, Maria / Saville, Kenneth / Schroeder, Stephanie / Shaffer, Christopher D / Sharif, Karim A / Sklensky, Diane E / Small, Chiyedza / Smith, Sheryl / Spokony, Rebecca / Sreenivasan, Aparna / Stamm, Joyce / Sterne-Marr, Rachel / Teeter, Katherine C / Thackeray, Justin / Thompson, Jeffrey S / Velazquez-Ulloa, Norma / Wolfe, Cindy / Youngblom, James / Yowler, Brian / Zhou, Leming / Brennan, Janie / Buhler, Jeremy / Leung, Wilson / Elgin, Sarah C R / Reed, Laura K

    Journal of microbiology & biology education

    2022  Band 23, Heft 2

    Abstract: The Genomics Education Partnership (GEP) engages students in a course-based undergraduate research experience (CURE). To better understand the student attributes that support success in this CURE, we asked students about their attitudes using previously ... ...

    Abstract The Genomics Education Partnership (GEP) engages students in a course-based undergraduate research experience (CURE). To better understand the student attributes that support success in this CURE, we asked students about their attitudes using previously published scales that measure epistemic beliefs about work and science, interest in science, and grit. We found, in general, that the attitudes students bring with them into the classroom contribute to two outcome measures, namely, learning as assessed by a pre- and postquiz and perceived self-reported benefits. While the GEP CURE produces positive outcomes overall, the students with more positive attitudes toward science, particularly with respect to epistemic beliefs, showed greater gains. The findings indicate the importance of a student's epistemic beliefs to achieving positive learning outcomes.
    Sprache Englisch
    Erscheinungsdatum 2022-05-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1935-7877
    ISSN 1935-7877
    DOI 10.1128/jmbe.00208-21
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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