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  1. AU=Raabe Vanessa N AU=Raabe Vanessa N
  2. AU="Neuville, C"
  3. AU="Leal Denis, M Florencia"
  4. AU=Wheeler Deric L AU=Wheeler Deric L
  5. AU="Prabhu S. Arunachalam"
  6. AU="Crețu, Oana Iulia"
  7. AU="Kim, Y G"
  8. AU=Lejuste Florian
  9. AU="Xavier-Carvalho, Caroline"
  10. AU="Lamb, Keith"
  11. AU="Şenbabaoğlu, Yasin"
  12. AU="Papaparaskeva, Kleo" AU="Papaparaskeva, Kleo"
  13. AU="Hanmer, Stuart B"
  14. AU="de Graaf, Gimon"
  15. AU=Bryan Nathan S
  16. AU="Bhatia, Chitra"
  17. AU="Neufeld, Niko"
  18. AU="Martínez-Cruz, Nayeli"
  19. AU="Joffe, Marshall M"
  20. AU="Wilunda, Calistus"
  21. AU="Das, Partha Pratim"
  22. AU="Staiano, Leopoldo"
  23. AU="Tibbatts, Clare"
  24. AU="Bandeira, Igor D"
  25. AU="Papathanassiou, Dimitri"
  26. AU="Mazurek, Camille"
  27. AU="Jenkinson, Crispin"
  28. AU="Hernández-Huérfano, Emilio Ernesto"
  29. AU="Conowall, Peter"
  30. AU="Nesan, Daniel"
  31. AU="Ueda, Takashi"
  32. AU="Yuan, Jiacheng"
  33. AU="Kahama, C B"
  34. AU="D’Alessio, Roberto"
  35. AU="Reuhl, Kenneth"
  36. AU="Seeleman, Conny"
  37. AU="Delaquis, Pascal"
  38. AU="Bommineni, Gopal R"
  39. AU="Kuhn, Cynthia M."
  40. AU="Olson, Jason C"
  41. AU="Buchholz, V."
  42. AU="Urquhart, Bradley L"
  43. AU="Ezaki, Kazune"
  44. AU="Choi, Jong Hyun"
  45. AU="Xie, Qiaowei"
  46. AU=Rojas-Marte G AU=Rojas-Marte G
  47. AU="Belli, A"
  48. AU="Moolman, M Charl"
  49. AU="Mazzoni, Stefania"
  50. AU=Stryjewski Martin E
  51. AU=Vallon Volker AU=Vallon Volker
  52. AU="Knowland, K E"
  53. AU="Beker, M. G."

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  1. Artikel ; Online: Diagnostic Testing for Crimean-Congo Hemorrhagic Fever.

    Raabe, Vanessa N

    Journal of clinical microbiology

    2020  Band 58, Heft 4

    Abstract: Crimean-Congo hemorrhagic fever is the most geographically widespread tick-borne virus, with infection resulting in mortality in up to 30% of cases. Clinical diagnosis alone is difficult due to the nonspecific nature of symptoms; therefore, laboratory ... ...

    Abstract Crimean-Congo hemorrhagic fever is the most geographically widespread tick-borne virus, with infection resulting in mortality in up to 30% of cases. Clinical diagnosis alone is difficult due to the nonspecific nature of symptoms; therefore, laboratory diagnostics should be utilized for patients with residence in or travel to regions of endemicity in whom the disease is suspected. This minireview provides an overview of laboratory tests available for Crimean-Congo hemorrhagic fever (CCHF) and their utility in diagnosis with a focus on diagnosing CCHF in humans.
    Mesh-Begriff(e) Diagnostic Techniques and Procedures ; Diagnostic Tests, Routine ; Hemorrhagic Fever Virus, Crimean-Congo ; Hemorrhagic Fever, Crimean/diagnosis ; Humans ; Travel
    Sprache Englisch
    Erscheinungsdatum 2020-03-25
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.01580-19
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: A Pregnant Adolescent with COVID-19 and Multisystem Inflammatory Syndrome in Children.

    Trostle, Megan E / Grossman, Tracy B / Penfield, Christina A / Phoon, Colin K L / Raabe, Vanessa N / Sloane, Mark F / Roman, Ashley S

    AJP reports

    2024  Band 14, Heft 1, Seite(n) e66–e68

    Abstract: Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can ...

    Abstract Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can be affected, pregnant adolescents and young adults are susceptible. However, there is scant information on how MIS-C may affect pregnancy and whether the presentation differs in the pregnant population. We report a case of a pregnant adolescent with COVID-19 and MIS-C with a favorable outcome. This case highlights the considerations in managing a critically ill pregnant patient with a novel illness and the importance of a multidisciplinary team in coordinating care.
    Sprache Englisch
    Erscheinungsdatum 2024-02-18
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2628074-7
    ISSN 2157-7005 ; 2157-6998
    ISSN (online) 2157-7005
    ISSN 2157-6998
    DOI 10.1055/s-0044-1779032
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Group B

    Raabe, Vanessa N / Shane, Andi L

    Microbiology spectrum

    2019  Band 7, Heft 2

    Abstract: Invasive disease due to group ... ...

    Abstract Invasive disease due to group B
    Mesh-Begriff(e) Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Female ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/microbiology ; Infant, Newborn, Diseases/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/microbiology ; Streptococcal Infections/drug therapy ; Streptococcal Infections/epidemiology ; Streptococcal Infections/microbiology ; Streptococcus agalactiae/classification ; Streptococcus agalactiae/pathogenicity
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2019-04-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/microbiolspec.GPP3-0007-2018
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: A Pregnant Adolescent with COVID-19 and Multisystem Inflammatory Syndrome in Children

    Trostle, Megan E. / Grossman, Tracy B. / Penfield, Christina A. / Phoon, Colin K. L. / Raabe, Vanessa N. / Sloane, Mark F. / Roman, Ashley S.

    American Journal of Perinatology Reports

    2024  Band 14, Heft 01, Seite(n) e66–e68

    Abstract: Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can ...

    Abstract Multisystem inflammatory syndrome in children (MIS-C), a new condition related to coronavirus disease 2019 (COVID-19) in the pediatric population, was recognized by physicians in the United Kingdom in April 2020. Given those up to the age of 21 years can be affected, pregnant adolescents and young adults are susceptible. However, there is scant information on how MIS-C may affect pregnancy and whether the presentation differs in the pregnant population. We report a case of a pregnant adolescent with COVID-19 and MIS-C with a favorable outcome. This case highlights the considerations in managing a critically ill pregnant patient with a novel illness and the importance of a multidisciplinary team in coordinating care.
    Schlagwörter multisystem inflammatory syndrome in children ; COVID-19 ; pregnancy ; critical illness
    Sprache Englisch
    Erscheinungsdatum 2024-01-01
    Verlag Thieme Medical Publishers, Inc.
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2628074-7
    ISSN 2157-7005 ; 2157-6998
    ISSN (online) 2157-7005
    ISSN 2157-6998
    DOI 10.1055/s-0044-1779032
    Datenquelle Thieme Verlag

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  5. Artikel ; Online: Importance of Pediatric Inclusion in COVID-19 Therapeutic Trials.

    Raabe, Vanessa N / Lighter, Jennifer / Caplan, Arthur L / Ratner, Adam J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Band 71, Heft 12, Seite(n) 3248–3249

    Abstract: Pediatric patients are excluded from most coronavirus disease 2019 (COVID-19) therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials, which enabled us to include children of all ages in a therapeutic COVID- ...

    Abstract Pediatric patients are excluded from most coronavirus disease 2019 (COVID-19) therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials, which enabled us to include children of all ages in a therapeutic COVID-19 trial at our institution.
    Mesh-Begriff(e) Adolescent ; COVID-19/drug therapy ; COVID-19/therapy ; Child ; Clinical Trials as Topic ; Coronavirus Infections ; Humans ; Immunization, Passive ; SARS-CoV-2 ; United States
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-05-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa656
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Importance of Pediatric Inclusion in COVID-19 Therapeutic Trials

    Raabe, Vanessa N / Lighter, Jennifer / Caplan, Arthur L / Ratner, Adam J

    Clin. infect. dis

    Abstract: Pediatric patients are excluded from most COVID-19 therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials with enabled us to include children of all ages in a therapeutic COVID-19 trial at our institution. ...

    Abstract Pediatric patients are excluded from most COVID-19 therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials with enabled us to include children of all ages in a therapeutic COVID-19 trial at our institution.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #381729
    Datenquelle COVID19

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  7. Artikel ; Online: Importance of Pediatric Inclusion in COVID-19 Therapeutic Trials

    Raabe, Vanessa N / Lighter, Jennifer / Caplan, Arthur L / Ratner, Adam J

    Clinical Infectious Diseases ; ISSN 1058-4838 1537-6591

    2020  

    Abstract: Abstract Pediatric patients are excluded from most coronavirus disease 2019 (COVID-19) therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials, which enabled us to include children of all ages in a ... ...

    Abstract Abstract Pediatric patients are excluded from most coronavirus disease 2019 (COVID-19) therapeutic trials. We outline a rationale for the inclusion of children in COVID-19 therapeutic trials, which enabled us to include children of all ages in a therapeutic COVID-19 trial at our institution.
    Schlagwörter Microbiology (medical) ; Infectious Diseases ; covid19
    Sprache Englisch
    Verlag Oxford University Press (OUP)
    Erscheinungsland uk
    Dokumenttyp Artikel ; Online
    DOI 10.1093/cid/ciaa656
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Hydroxychloroquine pre-exposure prophylaxis to prevent SARS-CoV-2 among health care workers at risk for SARS-CoV-2 exposure: A nonrandomized controlled trial

    Raabe, Vanessa N / Fleming, Andrew / Samanovic, Marie I / Lai, Lilin / Belli, Hayley M / Mulligan, Mark J / Belmont, H. Michael

    medRxiv

    Abstract: Background: Aerosol-generating procedures increase the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs). An effective pre-exposure prophylaxis would mitigate this risk. Objective: To ... ...

    Abstract Background: Aerosol-generating procedures increase the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs). An effective pre-exposure prophylaxis would mitigate this risk. Objective: To determine the efficacy of pre-exposure prophylactic hydroxychloroquine for the prevention of SARS-CoV-2 infection and symptomatic coronavirus 19 disease (COVID-19) among HCWs at high occupational risk of SARS-CoV-2 exposure. Methods: 130 HCWs in the New York University Langone Health System (NYULHS) who performed aerosol-generating procedures on patients with COVID-19 or provided bedside care for inpatients with COVID-19 or persons with suspected COVID-19 in an emergency department, for at least three shifts in a 7-day period, during the first 2020 COVID-19 wave in New York City were enrolled. Participants elected to take oral hydroxychloroquine, 600 mg on day 1 followed by 200 mg daily, or not take hydroxychloroquine for up to 90 days. Participants self-collected dried blood spots and completed digital questionnaires regarding COVID-19 symptoms, adverse events, and other COVID-19 medication use. Results: Six participants (7.5%) seroconverted during the trial: four who took hydroxychloroquine (6.8%) and two who declined hydroxychloroquine (9.5%). All participants not taking hydroxychloroquine reported COVID-19 symptoms at seroconversion compared to one of four participants (25%) who took hydroxychloroquine. Adverse events occurred in eight participants (9.6%) on hydroxychloroquine and were mostly mild. Conclusions: This study (ClinicalTrials.gov NCT04354870) did not demonstrate a statistically significant difference in SARS-CoV-2 seroconversion associated with hydroxychloroquine pre-exposure prophylaxis among HCWs at high risk of occupational SARS-CoV-2 exposure, although was underpowered and a high rate of hydroxychloroquine discontinuation was observed.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2022-07-03
    Verlag Cold Spring Harbor Laboratory Press
    Dokumenttyp Artikel ; Online
    DOI 10.1101/2022.07.01.22277058
    Datenquelle COVID19

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  9. Artikel ; Online: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Febrile Infants Without Respiratory Distress.

    Paret, Michal / Lighter, Jennifer / Pellett Madan, Rebecca / Raabe, Vanessa N / Shust, Gail F / Ratner, Adam J

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2020  Band 71, Heft 16, Seite(n) 2243–2245

    Abstract: We report 2 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) in infants presenting with fever in the absence of respiratory distress who required hospitalization for evaluation of possible invasive bacterial ... ...

    Abstract We report 2 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) in infants presenting with fever in the absence of respiratory distress who required hospitalization for evaluation of possible invasive bacterial infections. The diagnoses resulted from routine isolation and real-time reverse-transcription polymerase chain reaction-based testing for SARS-CoV-2 for febrile infants in an outbreak setting.
    Mesh-Begriff(e) COVID-19/diagnosis ; Dyspnea/virology ; Fever/virology ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Male ; Nasopharynx/virology ; Respiratory Distress Syndrome, Newborn ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-04-17
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciaa452
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Cellular and humoral immunity to Ebola Zaire glycoprotein and viral vector proteins following immunization with recombinant vesicular stomatitis virus-based Ebola vaccine (rVSVΔG-ZEBOV-GP).

    Raabe, Vanessa / Lai, Lilin / Morales, Juliet / Xu, Yongxian / Rouphael, Nadine / Davey, Richard T / Mulligan, Mark J

    Vaccine

    2023  Band 41, Heft 8, Seite(n) 1513–1523

    Abstract: While effective at preventing Zaire ebolavirus (ZEBOV) disease, cellular immunity to ZEBOV and vector-directed immunity elicited by the recombinant vesicular stomatitis virus expressing ZEBOV glycoprotein (rVSVΔG-ZEBOV-GP) vaccine remain poorly ... ...

    Abstract While effective at preventing Zaire ebolavirus (ZEBOV) disease, cellular immunity to ZEBOV and vector-directed immunity elicited by the recombinant vesicular stomatitis virus expressing ZEBOV glycoprotein (rVSVΔG-ZEBOV-GP) vaccine remain poorly understood. Sera and peripheral blood mononuclear cells were collected from 32 participants enrolled in a prospective multicenter study [ClinicalTrials.gov NCT02788227] before vaccination and up to six months post-vaccination. IgM and IgG antibodies, IgG-producing memory B cells (MBCs), and T cell reactivity to ZEBOV glycoprotein (ZEBOV-GP), vesicular stomatitis virus-Indiana strain (VSV-I) matrix (M) protein, and VSV-I nucleoprotein (NP) were measured using ELISA, ELISpot, and flow cytometry, respectively. 11/32 (34.4%) participants previously received a different investigational ZEBOV vaccine prior to enrollment and 21/32 (65.6%) participants were ZEBOV vaccine naïve. Both ZEBOV vaccine naïve and experienced participants had increased ZEBOV-GP IgG optical densities (ODs) post-rVSVΔG-ZEBOV-GP vaccination while only ZEBOV vaccine naïve participants had increased ZEBOV-GP IgM ODs. Transient IgM and IgG antibody responses to VSV-I M protein and NP were observed in a minority of participants. All participants had detectable ZEBOV-GP specific IgG-producing MBCs by 6 months post-vaccination while no changes were observed in the median IgG-producing MBCs to VSV-I proteins. T cell responses to ZEBOV-GP differed between ZEBOV vaccine experienced and ZEBOV vaccine naïve participants. T cell responses to both VSV-I M protein and VSV-I NP were observed, but were of a low magnitude. The rVSVΔG-ZEBOV-GP vaccine elicits robust humoral and memory B cell responses to ZEBOV glycoprotein in both ZEBOV vaccine naïve and experienced individuals and can generate vector-directed T cell immunity. Further research is needed to understand the significance of pre-existing vector and target antigen immunity on responses to booster doses of rVSVΔG-ZEBOV-GP and other rVSV-vectored vaccines.
    Mesh-Begriff(e) Animals ; Humans ; Hemorrhagic Fever, Ebola ; Ebolavirus ; Ebola Vaccines ; Viral Proteins ; Immunity, Humoral ; Democratic Republic of the Congo ; Leukocytes, Mononuclear ; Vesicular Stomatitis ; Prospective Studies ; Antibodies, Viral ; Vaccination ; Immunization ; Glycoproteins ; Immunoglobulin G ; Immunoglobulin M
    Chemische Substanzen Ebola Vaccines ; Viral Proteins ; Antibodies, Viral ; Glycoproteins ; Immunoglobulin G ; Immunoglobulin M
    Sprache Englisch
    Erscheinungsdatum 2023-01-31
    Erscheinungsland Netherlands
    Dokumenttyp Multicenter Study ; Journal Article ; Research Support, N.I.H., Intramural ; Research Support, N.I.H., Extramural
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2023.01.059
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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