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  1. Artikel ; Online: Sphenopalatine ganglion block for refractory COVID-19 headache: a descriptive case series.

    Machado, Felipe Chiodini / Carone Neto, Gilson / Carone, Rebeca Santiago Duarte

    Brazilian journal of anesthesiology (Elsevier)

    2021  Band 71, Heft 6, Seite(n) 667–669

    Abstract: Coronavirus SARS-CoV-2 is responsible for the COVID-19 pandemic, and headache is reported in 6.5% to 34% of all cases. There is little published evidence on the pharmacological treatment of COVID-19 headache. This case series presents six COVID-19 ... ...

    Abstract Coronavirus SARS-CoV-2 is responsible for the COVID-19 pandemic, and headache is reported in 6.5% to 34% of all cases. There is little published evidence on the pharmacological treatment of COVID-19 headache. This case series presents six COVID-19 infected patients with refractory headache in which intranasal bedside Sphenopalatine Ganglion Block was performed for analgesia. All patients had a reduction in headache intensity from severe to mild or no pain after the procedure with minor transient side effects. Proposed mechanisms of action include reduction of local autonomic stimuli, intracranial vasoconstriction, and reduction of vasoactive substances release in the pterygopalatine fossa.
    Mesh-Begriff(e) COVID-19 ; Headache/etiology ; Headache/therapy ; Humans ; Pandemics ; SARS-CoV-2 ; Sphenopalatine Ganglion Block
    Sprache Englisch
    Erscheinungsdatum 2021-04-28
    Erscheinungsland Brazil
    Dokumenttyp Case Reports
    ZDB-ID 1142792-9
    ISSN 0104-0014 ; 0104-0014
    ISSN (online) 0104-0014
    ISSN 0104-0014
    DOI 10.1016/j.bjane.2021.04.024
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients: a randomized controlled study.

    Machado, Felipe Chiodini / Palmeira, Claudia Carneiro de Araújo / Torres, João Nathanael Lima / Vieira, Joaquim Edson / Ashmawi, Hazem Adel

    Journal of pain research

    2018  Band 11, Seite(n) 2123–2129

    Abstract: Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in ... ...

    Abstract Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population.
    Materials and methods: Patients with a body mass index of 35 kg/m
    Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1-9.6;
    Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients.
    Sprache Englisch
    Erscheinungsdatum 2018-10-02
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S172235
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Uso da buprenorfina transdérmica na dor aguda pós‐operatória: revisão sistemática.

    Machado, Felipe Chiodini / Neto, Gilson Carone / Paiva, Luisa Oliveira de / Soares, Tamiris Cristina / Nakamura, Ricardo Kenithi / Nascimento, Leonardo de Freitas / Campana, Camila Sato / Lustosa, Lia Alves Martins Mota / Cortez, Rachel Andrade / Ashmawi, Hazem Adel

    Brazilian journal of anesthesiology (Elsevier)

    2020  Band 70, Heft 4, Seite(n) 419–428

    Abstract: Background and objectives: Postoperative pain is still a major concern in several surgical procedures. Multimodal analgesia is best for postoperative pain management; however, opioid therapy is still the main treatment for pain after surgical procedures. ...

    Titelübersetzung Transdermal buprenorphine for acute postoperative pain: a systematic review.
    Abstract Background and objectives: Postoperative pain is still a major concern in several surgical procedures. Multimodal analgesia is best for postoperative pain management; however, opioid therapy is still the main treatment for pain after surgical procedures. Transdermal buprenorphine is a partial μ agonist opioid widely used for chronic pain syndromes, with limited evidence for acute postoperative pain. A systematic review of studies examining transdermal buprenorphine for acute pain management after surgery was conducted.
    Contents: Data from PubMed, Embase, The Cochrane Central Register of Controlled Trials (CENTRAL), CINAHL via EBSCOhost, and LILACS were reviewed, including randomized clinical trials that evaluated total postoperative pain, postoperative analgesic consumption, drug-related side effects and patient satisfaction with analgesia regimen. Data from nine studies (615 patients) were included in this review. Most studies initiated transdermal buprenorphine use 6 to 48 hours before surgery, maintaining use from 1 to 8 days after the procedure. Most studies showed lower or similar postoperative pain scores, postoperative analgesic consumption and patient satisfaction comparing buprenorphine to placebo, tramadol, celecoxib, flurbiprofen and parecoxib. The incidence of side effects varied between studies, with most showing no increase in drug-related side effects with buprenorphine use, except one study, which compared buprenorphine to oral tramadol, and one to transdermal fentanyl. However, most results were derived from evidence with an overall high or unclear risk of bias.
    Conclusions: Although more studies are necessary, initial results show that transdermal buprenorphine seems to be an effective and safe opioid choice for management of acute postoperative pain.
    Mesh-Begriff(e) Administration, Cutaneous ; Analgesics, Opioid/administration & dosage ; Analgesics, Opioid/adverse effects ; Buprenorphine/administration & dosage ; Buprenorphine/adverse effects ; Humans ; Pain Measurement ; Pain, Postoperative/drug therapy ; Patient Satisfaction ; Randomized Controlled Trials as Topic ; Time Factors
    Chemische Substanzen Analgesics, Opioid ; Buprenorphine (40D3SCR4GZ)
    Sprache Portugiesisch
    Erscheinungsdatum 2020-07-08
    Erscheinungsland Brazil
    Dokumenttyp Comparative Study ; Journal Article ; Systematic Review
    ISSN 2352-2291
    ISSN (online) 2352-2291
    DOI 10.1016/j.bjan.2020.04.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Intraoperative use of methadone improves control of postoperative pain in morbidly obese patients

    Machado FC / Palmeira CCA / Torres JNL / Vieira JE / Ashmawi HA

    Journal of Pain Research, Vol Volume 11, Pp 2123-

    a randomized controlled study

    2018  Band 2129

    Abstract: Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim ...

    Abstract Felipe Chiodini Machado, Claudia Carneiro de Araújo Palmeira, João Nathanael Lima Torres, Joaquim Edson Vieira, Hazem Adel Ashmawi Anesthesiology Department, hcFMUsP, Universidade de São Paulo, São Paulo, Brazil Objectives: Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population. Materials and methods: Patients with a body mass index of 35 kg/m2 or more undergoing bariatric surgery were randomly assigned to receive either fentanyl (group F) or methadone (group M) in anesthesia induction and maintenance. The primary outcome was morphine consumption during the first 24 hours after surgery through a patient-controlled analgesia device. Secondary outcomes were pain scores at rest and while coughing, opioid related side effects, and patient satisfaction. The patients were also evaluated 3 months after surgery for the presence of pain, dysesthesia, or paresthesia at surgical site. Results: Postoperative morphine consumption was significantly higher for patients receiving fentanyl than methadone during the postoperative period at 2 hours (mean difference [MD] 6.4 mg; 95% CI 3.1–9.6; P<0.001), 2–6 hours (MD 11.4 mg; 95% CI 6.5–16.2; P<0.001), 6–24 hours (MD 10.4 mg; 95% CI 5.0–15.7; P<0.001), and 24–48 hours (MD 14.5 mg; 95% CI 3.9–25.1; P=0.01). Patients from group F had higher pain scores until 24 hours postoperatively, higher incidence of nausea and vomiting, lower satisfaction, and more evoked pain at surgical scar at the 3-month postoperative evaluation than group M. Conclusion: Intraoperative methadone can safely lower postoperative opioid consumption and improve postoperative pain scores compared with fentanyl in morbidly obese patients. Keywords: postoperative pain, bariatric surgery, acute pain, postoperative pain, methadone
    Schlagwörter Methadone ; Bariatric surgery ; Acute pain ; Postoperative pain ; Medicine (General) ; R5-920
    Sprache Englisch
    Erscheinungsdatum 2018-10-01T00:00:00Z
    Verlag Dove Medical Press
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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