LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 121

Suchoptionen

  1. Artikel ; Online: Monitoring lung recruitment.

    Cammarota, Gianmaria / Vaschetto, Rosanna / Vetrugno, Luigi / Maggiore, Salvatore M

    Current opinion in critical care

    2024  Band 30, Heft 3, Seite(n) 268–274

    Abstract: Purpose of review: This review explores lung recruitment monitoring, covering techniques, challenges, and future perspectives.: Recent findings: Various methodologies, including respiratory system mechanics evaluation, arterial bold gases (ABGs) ... ...

    Abstract Purpose of review: This review explores lung recruitment monitoring, covering techniques, challenges, and future perspectives.
    Recent findings: Various methodologies, including respiratory system mechanics evaluation, arterial bold gases (ABGs) analysis, lung imaging, and esophageal pressure (Pes) measurement are employed to assess lung recruitment. In support to ABGs analysis, the assessment of respiratory mechanics with hysteresis and recruitment-to-inflation ratio has the potential to evaluate lung recruitment and enhance mechanical ventilation setting. Lung imaging tools, such as computed tomography scanning, lung ultrasound, and electrical impedance tomography (EIT) confirm their utility in following lung recruitment with the advantage of radiation-free and repeatable application at the bedside for sonography and EIT. Pes enables the assessment of dorsal lung tendency to collapse through end-expiratory transpulmonary pressure. Despite their value, these methodologies may require an elevated expertise in their application and data interpretation. However, the information obtained by these methods may be conveyed to build machine learning and artificial intelligence algorithms aimed at improving the clinical decision-making process.
    Summary: Monitoring lung recruitment is a crucial component of managing patients with severe lung conditions, within the framework of a personalized ventilatory strategy. Although challenges persist, emerging technologies offer promise for a personalized approach to care in the future.
    Mesh-Begriff(e) Humans ; Monitoring, Physiologic/methods ; Respiration, Artificial/methods ; Respiratory Mechanics/physiology ; Lung/diagnostic imaging ; Lung/physiopathology ; Electric Impedance ; Tomography, X-Ray Computed ; Blood Gas Analysis/methods ; Ultrasonography/methods
    Sprache Englisch
    Erscheinungsdatum 2024-03-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000001157
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel: Reverse Triggered Breath during Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist at Increasing Propofol Infusion.

    Longhini, Federico / Simonte, Rachele / Vaschetto, Rosanna / Navalesi, Paolo / Cammarota, Gianmaria

    Journal of clinical medicine

    2023  Band 12, Heft 14

    Abstract: Background: Reverse triggered breath (RTB) has been extensively described during assisted-controlled modes of ventilation. We aimed to assess whether RTB occurs during Pressure Support Ventilation (PSV) and Neurally Adjusted Ventilatory Assist (NAVA) at ...

    Abstract Background: Reverse triggered breath (RTB) has been extensively described during assisted-controlled modes of ventilation. We aimed to assess whether RTB occurs during Pressure Support Ventilation (PSV) and Neurally Adjusted Ventilatory Assist (NAVA) at varying depths of propofol sedation.
    Methods: This is a retrospective analysis of a prospective crossover randomized controlled trial conducted in an Intensive Care Unit (ICU) of a university hospital. Fourteen intubated patients for acute respiratory failure received six trials of 25 minutes randomly applying PSV and NAVA at three different propofol infusions: awake, light, and deep sedation. We assessed the occurrence of RTBs at each protocol step. The incidence level of RTBs was determined through the RTB index, which was calculated by dividing RTBs by the total number of breaths triggered and not triggered.
    Results: RTBs occurred during both PSV and NAVA. The RTB index was greater during PSV than during NAVA at mild (1.5 [0.0; 5.3]% vs. 0.6 [0.0; 1.1]%) and deep (5.9 [0.7; 9.0]% vs. 1.7 [0.9; 3.5]%) sedation.
    Conclusions: RTB occurs in patients undergoing assisted mechanical ventilation. The level of propofol sedation and the mode of ventilation may influence the incidence of RTBs.
    Sprache Englisch
    Erscheinungsdatum 2023-07-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12144857
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel: Is it feasible to collect exhaled breath condensate in COVID-19 patients undergoing noninvasive ventilatory support?

    Pierucci, Paola / Vaschetto, Rosanna / Carpagnano, Giovanna E

    ERJ open research

    2021  Band 7, Heft 2

    Abstract: In patients with #COVID19-related acute hypoxic respiratory failure requiring noninvasive ventilatory support, EBC collection with adequate precautions may be feasible and future studies will be needed to explore this research ... ...

    Abstract In patients with #COVID19-related acute hypoxic respiratory failure requiring noninvasive ventilatory support, EBC collection with adequate precautions may be feasible and future studies will be needed to explore this research field
    Sprache Englisch
    Erscheinungsdatum 2021-05-24
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00071-2021
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Is it feasible to collect exhaled breath condensate in COVID-19 patients undergoing noninvasive ventilatory support?

    Paola Pierucci / Rosanna Vaschetto / Giovanna E. Carpagnano

    ERJ Open Research, Vol 7, Iss

    2021  Band 2

    Schlagwörter Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2021-05-01T00:00:00Z
    Verlag European Respiratory Society
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  5. Artikel ; Online: Diaphragmatic excursion tissue Doppler sonographic assessment.

    Cammarota, Gianmaria / Boniolo, Ester / Tarquini, Riccardo / Vaschetto, Rosanna

    Intensive care medicine

    2020  Band 46, Heft 9, Seite(n) 1759–1760

    Mesh-Begriff(e) Diaphragm/diagnostic imaging ; Humans ; Ultrasonography ; Ultrasonography, Doppler
    Sprache Englisch
    Erscheinungsdatum 2020-03-25
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06015-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Ten tips to optimize weaning and extubation success in the critically ill.

    Jung, Boris / Vaschetto, Rosanna / Jaber, Samir

    Intensive care medicine

    2020  Band 46, Heft 12, Seite(n) 2461–2463

    Mesh-Begriff(e) Airway Extubation ; Critical Illness ; Humans ; Respiration, Artificial ; Ventilator Weaning ; Weaning
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-10-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06300-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel: The Role of New Morphological Parameters Provided by the BC 6800 Plus Analyzer in the Early Diagnosis of Sepsis.

    Sacchetti, Sara / Vidali, Matteo / Esposito, Teresa / Zorzi, Stefano / Burgener, Alessia / Ciccarello, Lorenzo / Cammarota, Gianmaria / Zanotti, Valentina / Giacomini, Luca / Bellan, Mattia / Pirisi, Mario / Lopez, Ramon Simon / Dianzani, Umberto / Vaschetto, Rosanna / Rolla, Roberta

    Diagnostics (Basel, Switzerland)

    2024  Band 14, Heft 3

    Abstract: Background: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that reflect the cell morphology of blood cells, ... ...

    Abstract Background: Late diagnosis of sepsis is associated with adverse consequences and high mortality rate. The aim of this study was to evaluate the diagnostic value of hematologic research parameters, that reflect the cell morphology of blood cells, available on the BC 6800 plus automated analyzer (Mindray) for the early detection of sepsis.
    Materials and methods: A complete blood count (CBC) was performed by Mindray BC 6800 Plus Analyzer in 327 patients (223 with a confirmed diagnosis of sepsis following sepsis-3 criteria, 104 without sepsis), admitted at the Intensive Care Unit of the Novara's Hospital (Italy) and in 56 patients with localized infection.
    Results: In univariate logistic regression, age, Hb, RDW, MO#, NMR, NeuX, NeuY, NeuZ, LymX, MonX, MonY, MonZ were associated with sepsis (
    Conclusions: In addition to already established biomarkers and basic CBC parameters, new morphological cell parameters can be a valuable aid in the early diagnosis of sepsis at no additional cost.
    Sprache Englisch
    Erscheinungsdatum 2024-02-04
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14030340
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: Personalised mechanical ventilation in acute respiratory distress syndrome: the right idea with the wrong tools?

    Mongodi, Silvia / Santangelo, Erminio / Bouhemad, Bélaïd / Vaschetto, Rosanna / Mojoli, Francesco

    The Lancet. Respiratory medicine

    2020  Band 7, Heft 12, Seite(n) e38

    Mesh-Begriff(e) France ; Humans ; Positive-Pressure Respiration ; Respiration, Artificial ; Respiratory Distress Syndrome ; Single-Blind Method
    Sprache Englisch
    Erscheinungsdatum 2020-08-03
    Erscheinungsland England
    Dokumenttyp Letter ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(19)30353-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: High levels of circulating osteopontin in inflammatory lung disease regardless of SARS-CoV-2 infection.

    Cappellano, Giuseppe / Abreu, Hugo / Raineri, Davide / Scotti, Lorenza / Castello, Luigi / Vaschetto, Rosanna / Chiocchetti, Annalisa

    EMBO molecular medicine

    2021  Band 13, Heft 11, Seite(n) e15217

    Sprache Englisch
    Erscheinungsdatum 2021-11-03
    Erscheinungsland England
    Dokumenttyp Published Erratum
    ZDB-ID 2467145-9
    ISSN 1757-4684 ; 1757-4676
    ISSN (online) 1757-4684
    ISSN 1757-4676
    DOI 10.15252/emmm.202115217
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: Plasma Redox Balance in Advanced-Maternal-Age Pregnant Women and Effects of Plasma on Umbilical Cord Mesenchymal Stem Cells.

    Grossini, Elena / Aquino, Carmen Imma / Venkatesan, Sakthipriyan / Troìa, Libera / Tizzoni, Eleonora / Fumagalli, Federica / Ferrante, Daniela / Vaschetto, Rosanna / Remorgida, Valentino / Surico, Daniela

    International journal of molecular sciences

    2024  Band 25, Heft 9

    Abstract: Pregnancy at advanced maternal age (AMA) is a condition of potential risk for the development of maternal-fetal complications with possible repercussions even in the long term. Here, we analyzed the changes in plasma redox balance and the effects of ... ...

    Abstract Pregnancy at advanced maternal age (AMA) is a condition of potential risk for the development of maternal-fetal complications with possible repercussions even in the long term. Here, we analyzed the changes in plasma redox balance and the effects of plasma on human umbilical cord mesenchymal cells (hUMSCs) in AMA pregnant women (patients) at various timings of pregnancy. One hundred patients and twenty pregnant women younger than 40 years (controls) were recruited and evaluated at various timings during pregnancy until after delivery. Plasma samples were used to measure the thiobarbituric acid reactive substances (TBARS), glutathione and nitric oxide (NO). In addition, plasma was used to stimulate the hUMSCs, which were tested for cell viability, reactive oxygen species (ROS) and NO release. The obtained results showed that, throughout pregnancy until after delivery in patients, the levels of plasma glutathione and NO were lower than those of controls, while those of TBARS were higher. Moreover, plasma of patients reduced cell viability and NO release, and increased ROS release in hUMSCs. Our results highlighted alterations in the redox balance and the presence of potentially harmful circulating factors in plasma of patients. They could have clinical relevance for the prevention of complications related to AMA pregnancy.
    Mesh-Begriff(e) Humans ; Female ; Pregnancy ; Adult ; Mesenchymal Stem Cells/metabolism ; Oxidation-Reduction ; Maternal Age ; Reactive Oxygen Species/metabolism ; Nitric Oxide/metabolism ; Nitric Oxide/blood ; Thiobarbituric Acid Reactive Substances/metabolism ; Umbilical Cord/cytology ; Umbilical Cord/metabolism ; Glutathione/metabolism ; Glutathione/blood ; Cell Survival ; Oxidative Stress ; Plasma/metabolism
    Chemische Substanzen Reactive Oxygen Species ; Nitric Oxide (31C4KY9ESH) ; Thiobarbituric Acid Reactive Substances ; Glutathione (GAN16C9B8O)
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25094869
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang