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  1. Artikel ; Online: Editorial: Infectious Disease Epidemiology and Transmission Dynamics.

    Du, Zhanwei / Luo, Wei / Sippy, Rachel / Wang, Lin

    Viruses

    2023  Band 15, Heft 1

    Abstract: Infectious diseases, such as COVID-19 [ ... ]. ...

    Abstract Infectious diseases, such as COVID-19 [...].
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; Communicable Diseases/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-01-15
    Erscheinungsland Switzerland
    Dokumenttyp Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15010246
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Understanding the impact of rapid antigen tests on SARS-CoV-2 transmission in the fifth wave of COVID-19 in Hong Kong in early 2022.

    Du, Zhanwei / Tian, Linwei / Jin, Dong-Yan

    Emerging microbes & infections

    2023  Band 11, Heft 1, Seite(n) 1394–1401

    Abstract: The fast-spreading Omicron variant of SARS-CoV-2 overwhelmed Hong Kong, causing the fifth wave of COVID-19. It remains to be determined what mitigation measures might have played a role in reversing the rising trend of confirmed cases in this major ... ...

    Abstract The fast-spreading Omicron variant of SARS-CoV-2 overwhelmed Hong Kong, causing the fifth wave of COVID-19. It remains to be determined what mitigation measures might have played a role in reversing the rising trend of confirmed cases in this major outbreak. The government of Hong Kong has launched the mass rapid antigen tests (RAT) in the population and the StayHomeSafe scheme since February 2022. In this study, we examined the impact of the mass RAT on disease transmission and the case fatality ratio. It was suggested that the implementation of RAT plausibly played a role in the steady decrease of the effective reproduction number, leading to diminished SARS-CoV-2 transmission. In addition, we projected the disease burden of the outbreak in a scenario analysis to highlight the necessity of the StayHomeSafe scheme in Hong Kong. The Omicron outbreak experience in Hong Kong may provide actionable insights for navigating the challenges of COVID-19 surges in other regions and countries.
    Mesh-Begriff(e) COVID-19/diagnosis ; COVID-19/epidemiology ; Disease Outbreaks ; Hong Kong/epidemiology ; Humans ; SARS-CoV-2/genetics
    Sprache Englisch
    Erscheinungsdatum 2023-03-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2681359-2
    ISSN 2222-1751 ; 2222-1751
    ISSN (online) 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2022.2076616
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Reproduction numbers of SARS-CoV-2 Omicron subvariants.

    Wang, Shuqi / Zhang, Fengdi / Wang, Zhen / Du, Zhanwei / Gao, Chao

    Journal of travel medicine

    2022  Band 29, Heft 8

    Mesh-Begriff(e) Humans ; COVID-19 ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2022-09-27
    Erscheinungsland England
    Dokumenttyp Research Support, Non-U.S. Gov't ; Letter
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taac108
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Real-world effectiveness of monkeypox vaccines: a systematic review.

    Xu, Mingda / Liu, Caifen / Du, Zhanwei / Bai, Yuan / Wang, Zhen / Gao, Chao

    Journal of travel medicine

    2023  Band 30, Heft 5

    Mesh-Begriff(e) Humans ; Mpox (monkeypox)/prevention & control ; Smallpox Vaccine
    Chemische Substanzen Smallpox Vaccine
    Sprache Englisch
    Erscheinungsdatum 2023-04-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad048
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  5. Artikel ; Online: Rethinking Academic Conferences in the Age of Pandemic

    Qing Cai / Zhanwei Du / Ye Wu / Xiaoke Xu

    Applied Sciences, Vol 12, Iss 16, p

    2022  Band 8351

    Abstract: The year 2020 witnessed the havoc wreaked by the coronavirus disease COVID-19 due to its onset in late 2019. The COVID-19 pandemic is the cruelest public health crisis humankind has ever seen. The COVID-19 pandemic profoundly affected every walk of life, ...

    Abstract The year 2020 witnessed the havoc wreaked by the coronavirus disease COVID-19 due to its onset in late 2019. The COVID-19 pandemic is the cruelest public health crisis humankind has ever seen. The COVID-19 pandemic profoundly affected every walk of life, and academic research has been no exception. Academic conferences are an indispensable component of research. Note that the pandemic together with its variants ravaged the globe in 2020, while their recurrences yet have a deep shadow across 2021 and 2022 with uncertainties for the near future. Under the sway of the pandemic, many conferences are conducted in virtual mode to mitigate the propagation of the virus. It is no surprise that academic conferences charge the attendees for registration fees with the amount varying by countries and disciplines. Here, we collect the registration fee information for conferences held in 2019, 2020 and 2021. Note that virtual conferences barely cater to attendees except by providing online platforms. However, we discover that most of the virtual conferences held in 2020 and 2021 still charged high registration fees compared to those in 2019, while the remaining conferences only applied small discounts. In light of the current situation of the pandemic as well as uncertainties in the future, virtual conferences could be a common form of academic activity. Considering the sluggish global economy at well as other potential issues, here, we advocate that going virtual should always be an option for academic conferences in the future. We also suggest that virtual conferences should charge less and the expenditure of the fees should be open to the public.
    Schlagwörter COVID-19 ; academic conference ; virtual conference ; registration fee ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 027
    Sprache Englisch
    Erscheinungsdatum 2022-08-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Estimate of COVID-19 Deaths, China, December 2022-February 2023.

    Du, Zhanwei / Wang, Yuchen / Bai, Yuan / Wang, Lin / Cowling, Benjamin John / Meyers, Lauren Ancel

    Emerging infectious diseases

    2023  Band 29, Heft 10, Seite(n) 2121–2124

    Abstract: China announced a slight easing of its zero-COVID rules on November 11, 2022, and then a major relaxation on December 7, 2022. We estimate that the ensuing wave of SARS-CoV-2 infections caused 1.41 million deaths in China during December 2022-February ... ...

    Abstract China announced a slight easing of its zero-COVID rules on November 11, 2022, and then a major relaxation on December 7, 2022. We estimate that the ensuing wave of SARS-CoV-2 infections caused 1.41 million deaths in China during December 2022-February 2023, substantially higher than that reported through official channels.
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; SARS-CoV-2 ; China/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-08-28
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2910.230585
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 4778: Hefte anzeigen Standort:
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  7. Artikel ; Online: Coupling the circadian rhythms of population movement and the immune system in infectious disease modeling.

    Zhanwei Du / Petter Holme

    PLoS ONE, Vol 15, Iss 6, p e

    2020  Band 0234619

    Abstract: The dynamics of infectious diseases propagating in populations depends both on human interaction patterns, the contagion process and the pathogenesis within hosts. The immune system follows a circadian rhythm and, consequently, the chance of getting ... ...

    Abstract The dynamics of infectious diseases propagating in populations depends both on human interaction patterns, the contagion process and the pathogenesis within hosts. The immune system follows a circadian rhythm and, consequently, the chance of getting infected varies with the time of day an individual is exposed to the pathogen. The movement and interaction of people also follow 24-hour cycles, which couples these two phenomena. We use a stochastic metapopulation model informed by hourly mobility data for two medium-sized Chinese cities. By this setup, we investigate how the epidemic risk depends on the difference of the clocks governing the population movement and the immune systems. In most of the scenarios we test, we observe circadian rhythms would constrain the pace and extent of disease emergence. The three measures (strength, outward transmission and introduction speeds) are highly correlated with each other. For example of the Yushu City, outward transmission speed and introduction speed are correlated with a Pearson's correlation coefficient of 0.83, and the speeds correlate to strength with coefficients of -0.85 and -0.75, respectively (all have p < 0.05), in simulations with no circadian effect and R0 = 1.5. The relation between the circadian rhythms of the immune system and daily routines in human mobility can affect the pace and extent of infectious disease spreading. Shifting commuting times could mitigate the emergence of outbreaks.
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 910
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Medical-Knowledge-Based Graph Neural Network for Medication Combination Prediction.

    Gao, Chao / Yin, Shu / Wang, Haiqiang / Wang, Zhen / Du, Zhanwei / Li, Xuelong

    IEEE transactions on neural networks and learning systems

    2023  Band PP

    Abstract: Medication combination prediction (MCP) can provide assistance for experts in the more thorough comprehension of complex mechanisms behind health and disease. Many recent studies focus on the patient representation from the historical medical records, ... ...

    Abstract Medication combination prediction (MCP) can provide assistance for experts in the more thorough comprehension of complex mechanisms behind health and disease. Many recent studies focus on the patient representation from the historical medical records, but neglect the value of the medical knowledge, such as the prior knowledge and the medication knowledge. This article develops a medical-knowledge-based graph neural network (MK-GNN) model which incorporates the representation of patients and the medical knowledge into the neural network. More specifically, the features of patients are extracted from their medical records in different feature subspaces. Then these features are concatenated to obtain the feature representation of patients. The prior knowledge, which is calculated according to the mapping relationship between medications and diagnoses, provides heuristic medication features according to the diagnosis results. Such medication features can help the MK-GNN model learn optimal parameters. Moreover, the medication relationship in prescriptions is formulated as a drug network to integrate the medication knowledge into medication representation vectors. The results reveal the superior performance of the MK-GNN model compared with the state-of-the-art baselines on different evaluation metrics. The case study manifests the application potential of the MK-GNN model.
    Sprache Englisch
    Erscheinungsdatum 2023-05-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2162-2388
    ISSN (online) 2162-2388
    DOI 10.1109/TNNLS.2023.3266490
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Coupling the circadian rhythms of population movement and the immune system in infectious disease modeling.

    Du, Zhanwei / Holme, Petter

    PloS one

    2020  Band 15, Heft 6, Seite(n) e0234619

    Abstract: The dynamics of infectious diseases propagating in populations depends both on human interaction patterns, the contagion process and the pathogenesis within hosts. The immune system follows a circadian rhythm and, consequently, the chance of getting ... ...

    Abstract The dynamics of infectious diseases propagating in populations depends both on human interaction patterns, the contagion process and the pathogenesis within hosts. The immune system follows a circadian rhythm and, consequently, the chance of getting infected varies with the time of day an individual is exposed to the pathogen. The movement and interaction of people also follow 24-hour cycles, which couples these two phenomena. We use a stochastic metapopulation model informed by hourly mobility data for two medium-sized Chinese cities. By this setup, we investigate how the epidemic risk depends on the difference of the clocks governing the population movement and the immune systems. In most of the scenarios we test, we observe circadian rhythms would constrain the pace and extent of disease emergence. The three measures (strength, outward transmission and introduction speeds) are highly correlated with each other. For example of the Yushu City, outward transmission speed and introduction speed are correlated with a Pearson's correlation coefficient of 0.83, and the speeds correlate to strength with coefficients of -0.85 and -0.75, respectively (all have p < 0.05), in simulations with no circadian effect and R0 = 1.5. The relation between the circadian rhythms of the immune system and daily routines in human mobility can affect the pace and extent of infectious disease spreading. Shifting commuting times could mitigate the emergence of outbreaks.
    Mesh-Begriff(e) China/epidemiology ; Circadian Rhythm ; Cities ; Communicable Diseases/epidemiology ; Communicable Diseases/transmission ; Disease Outbreaks/prevention & control ; Humans ; Immune System/physiology ; Models, Biological ; Movement/physiology
    Sprache Englisch
    Erscheinungsdatum 2020-06-16
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0234619
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  10. Artikel: Hundreds of severe pediatric COVID-19 infections in Wuhan prior to the lockdown.

    Du, Zhanwei / Nugent, Ciara / Cowling, Benjamin John / Meyers, Lauren Ancel

    medRxiv : the preprint server for health sciences

    2020  

    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-03-27
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2020.03.16.20037176
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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