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  1. Artikel ; Online: Melanocytic ocular surface squamous neoplasia successfully managed with no-touch excisional biopsy, cryotherapy and amniotic membrane transplantation.

    Giachos, Ioannis / Thaung, Caroline / Ting, Darren Shu Jeng

    Eye (London, England)

    2024  

    Sprache Englisch
    Erscheinungsdatum 2024-04-22
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-03069-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: ChatGPT in ophthalmology: the dawn of a new era?

    Ting, Darren Shu Jeng / Tan, Ting Fang / Ting, Daniel Shu Wei

    Eye (London, England)

    2023  Band 38, Heft 1, Seite(n) 4–7

    Mesh-Begriff(e) Ophthalmology ; Artificial Intelligence
    Sprache Englisch
    Erscheinungsdatum 2023-06-27
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02619-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Re: Bonini et al.: Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis (Ophthalmology. 2018;125:1332-1343).

    Ting, Darren Shu Jeng

    Ophthalmology

    2019  Band 126, Heft 2, Seite(n) e14–e15

    Mesh-Begriff(e) Double-Blind Method ; Humans ; Keratitis ; Nerve Growth Factor ; Trigeminal Nerve Diseases
    Chemische Substanzen Nerve Growth Factor (9061-61-4)
    Sprache Englisch
    Erscheinungsdatum 2019-01-26
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2018.09.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Comment on: The Impact of COVID-19 on Individuals Across the Spectrum of Visual Impairment.

    Ting, Darren Shu Jeng / Krause, Sherine / Said, Dalia G / Dua, Harminder S

    American journal of ophthalmology

    2021  Band 230, Seite(n) 303–304

    Mesh-Begriff(e) COVID-19 ; Humans ; SARS-CoV-2 ; Vision, Low
    Sprache Englisch
    Erscheinungsdatum 2021-05-11
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80030-2
    ISSN 1879-1891 ; 0002-9394
    ISSN (online) 1879-1891
    ISSN 0002-9394
    DOI 10.1016/j.ajo.2021.04.036
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Large language models in medicine.

    Thirunavukarasu, Arun James / Ting, Darren Shu Jeng / Elangovan, Kabilan / Gutierrez, Laura / Tan, Ting Fang / Ting, Daniel Shu Wei

    Nature medicine

    2023  Band 29, Heft 8, Seite(n) 1930–1940

    Abstract: Large language models (LLMs) can respond to free-text queries without being specifically trained in the task in question, causing excitement and concern about their use in healthcare settings. ChatGPT is a generative artificial intelligence (AI) chatbot ... ...

    Abstract Large language models (LLMs) can respond to free-text queries without being specifically trained in the task in question, causing excitement and concern about their use in healthcare settings. ChatGPT is a generative artificial intelligence (AI) chatbot produced through sophisticated fine-tuning of an LLM, and other tools are emerging through similar developmental processes. Here we outline how LLM applications such as ChatGPT are developed, and we discuss how they are being leveraged in clinical settings. We consider the strengths and limitations of LLMs and their potential to improve the efficiency and effectiveness of clinical, educational and research work in medicine. LLM chatbots have already been deployed in a range of biomedical contexts, with impressive but mixed results. This review acts as a primer for interested clinicians, who will determine if and how LLM technology is used in healthcare for the benefit of patients and practitioners.
    Mesh-Begriff(e) Humans ; Artificial Intelligence ; Medicine ; Language ; Software ; Technology
    Sprache Englisch
    Erscheinungsdatum 2023-07-17
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02448-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The impact of COVID-19 pandemic on ophthalmology services: are we ready for the aftermath?

    Ting, Darren Shu Jeng / Deshmukh, Rashmi / Said, Dalia G / Dua, Harminder S

    Therapeutic advances in ophthalmology

    2020  Band 12, Seite(n) 2515841420964099

    Sprache Englisch
    Erscheinungsdatum 2020-10-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2515-8414
    ISSN (online) 2515-8414
    DOI 10.1177/2515841420964099
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Comparative Study of Primary SMILE, SMILE Enhancement, and Femtosecond Laser-Assisted LASIK on Higher Order Aberrations and Corneal Densitometry.

    Foo, Valencia Hui Xian / Liu, Yu-Chi / Ang, Marcus / Htoon, Hla Myint / Ting, Darren Shu Jeng / Mehta, Jodhbir S

    Journal of refractive surgery (Thorofare, N.J. : 1995)

    2024  Band 40, Heft 5, Seite(n) e291–e303

    Abstract: Purpose: To compare differences in corneal densitometry (CD) and higher order aberrations (HOAs) in eyes that underwent small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for the treatment ... ...

    Abstract Purpose: To compare differences in corneal densitometry (CD) and higher order aberrations (HOAs) in eyes that underwent small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for the treatment of myopia and myopic astigmatism at postoperative months 3, 6, and 12, and to evaluate their changes in a separate cohort of eyes after SMILE enhancement.
    Methods: In this prospective, randomized, paired-eye clinical trial, consecutive eligible participants were randomized to undergo SMILE or FS-LASIK in either eye. Main outcome measures were CD and HOAs preoperatively and at 3, 6, and 12 months postoperatively. A separate cohort of consecutive patients who had SMILE and underwent enhancement were also included for comparison.
    Results: For CD, no significant differences were found between SMILE and FS-LASIK up to month 12. For HOA measured by wavefront aberrometry, both SMILE and FS-LASIK had an increase in total root mean square (RMS) HOAs, spherical aberration (SA), and vertical coma up to month 12. SMILE had an additional increase in vertical quatrefoil, and FS-LASIK had an increase in horizontal coma at month 12. FS-LASIK had higher SA than SMILE, whereas SMILE had higher vertical quatrefoil than FS-LASIK at month 12. Central and posterior zone CD had significantly decreased after SMILE enhancement compared to after primary SMILE up to 2 years after enhancement. RMS HOAs, lower order aberrations, and SA were all increased after SMILE enhancement compared to after primary SMILE.
    Conclusions: SMILE induced lower SA but higher vertical quatrefoil than FS-LASIK at 1 year. Both SMILE and FS-LASIK had similar increases in RMS HOAs and vertical coma up to 1 year. There were no differences in CD between both groups. SMILE enhancement additionally had decreased central and posterior CD but greater RMS HOAs and SA compared to primary SMILE.
    Mesh-Begriff(e) Humans ; Keratomileusis, Laser In Situ/methods ; Corneal Wavefront Aberration/physiopathology ; Prospective Studies ; Myopia/surgery ; Myopia/physiopathology ; Adult ; Female ; Male ; Lasers, Excimer/therapeutic use ; Visual Acuity/physiology ; Corneal Stroma/surgery ; Cornea/surgery ; Cornea/physiopathology ; Young Adult ; Densitometry ; Aberrometry ; Refraction, Ocular/physiology ; Astigmatism/surgery ; Astigmatism/physiopathology ; Corneal Surgery, Laser/methods ; Corneal Topography
    Sprache Englisch
    Erscheinungsdatum 2024-05-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Comparative Study ; Randomized Controlled Trial
    ZDB-ID 1264796-2
    ISSN 1938-2391 ; 0883-0444 ; 1081-597X ; 1081-0803
    ISSN (online) 1938-2391
    ISSN 0883-0444 ; 1081-597X ; 1081-0803
    DOI 10.3928/1081597X-20240314-01
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Interface Haze After Descemet Stripping Automated Endothelial Keratoplasty.

    Ting, Darren Shu Jeng / Said, Dalia G / Dua, Harminder S

    JAMA ophthalmology

    2019  Band 137, Heft 10, Seite(n) 1201–1202

    Sprache Englisch
    Erscheinungsdatum 2019-08-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2019.2745
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review.

    Ahmmed, Afsara A / Ting, Darren Shu Jeng / Figueiredo, Francisco C

    The ocular surface

    2021  Band 20, Seite(n) 199–211

    Abstract: Ocular surface chemical injury (OSCI) is a common type of ocular emergency that can potentially cause significant and permanent visual impairment. However, the global prevalence, demographic factors, socioeconomic burden, and psychological impact of OSCI ...

    Abstract Ocular surface chemical injury (OSCI) is a common type of ocular emergency that can potentially cause significant and permanent visual impairment. However, the global prevalence, demographic factors, socioeconomic burden, and psychological impact of OSCI have not been well investigated or reported. This review aims to provide a comprehensive overview of these aspects, highlight gaps in the literature, and advocate key strategies in reducing the incidence of OSCI. OSCI was responsible for 0.1-15% of all ocular emergency presentations, with an estimated incidence of 5.1-50 per 100,000 population-year. Young working adult men were the most at-risk group, though high rates of OSCI were also observed in young children in developed countries, especially from detergent pods. Low- and middle-income countries were noted to have higher proportions of assault-related and pediatric OSCI cases, often with more severe presentations. Direct and indirect costs for some hospitalized patients led to loss of all personal and household income after the injury. Emergency department costs in the United States were estimated at $106.7 million over four years and costs of treating long term complications such as glaucoma were estimated to be as high as $93,003 over five years. Significant negative impacts on visual and health-related quality of life and psychological well-being have been reported after injury, with higher rates of anxiety, depression, and psychological distress compared to the general population.
    Mesh-Begriff(e) Adult ; Burns, Chemical ; Child ; Child, Preschool ; Eye Injuries ; Humans ; Incidence ; Male ; Prevalence ; Quality of Life ; United States
    Sprache Englisch
    Erscheinungsdatum 2021-02-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2208578-6
    ISSN 1937-5913 ; 1542-0124
    ISSN (online) 1937-5913
    ISSN 1542-0124
    DOI 10.1016/j.jtos.2021.02.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Acute corneal perforation 1 week following uncomplicated cataract surgery: the implication of undiagnosed dry eye disease and topical NSAIDs.

    Ting, Darren Shu Jeng / Ghosh, Saurabh

    Therapeutic advances in ophthalmology

    2019  Band 11, Seite(n) 2515841419869508

    Abstract: Dry eye disease is a common ocular surface disease in patients who are undergoing cataract surgery. The significance of dry eye disease is often underestimated or overlooked during preoperative assessment of cataract. We report an 80-year-old patient, ... ...

    Abstract Dry eye disease is a common ocular surface disease in patients who are undergoing cataract surgery. The significance of dry eye disease is often underestimated or overlooked during preoperative assessment of cataract. We report an 80-year-old patient, with a background of seropositive rheumatoid arthritis and diabetes, who presented with an acute corneal melt and perforation associated with undiagnosed dry eye disease and use of topical ketorolac 1 week following an uncomplicated cataract surgery. The patient underwent repeated corneal gluing for corneal perforation and was subsequently diagnosed and treated for bilateral moderate-severe dry eye disease. This case highlights the importance of meticulous preoperative assessment and management of the ocular surface, especially in patients with systemic diseases such as rheumatoid arthritis and diabetes prior to cataract surgery. The implication of the use of topical nonsteroidal anti-inflammatory drugs following cataract surgery - which might have contributed to the process of corneal melt in our case - is also discussed.
    Sprache Englisch
    Erscheinungsdatum 2019-08-12
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ISSN 2515-8414
    ISSN (online) 2515-8414
    DOI 10.1177/2515841419869508
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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