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  1. Artikel: Screening guide for hepatitis C virus infection in Spain.

    Crespo, Javier

    Gastroenterologia y hepatologia

    2020  Band 44, Heft 3, Seite(n) 181–182

    Titelübersetzung Guía de cribado de la infección por el virus de la hepatitis C en España.
    Mesh-Begriff(e) Hepatitis C/diagnosis ; Humans ; Mass Screening ; Practice Guidelines as Topic ; Spain
    Sprache Spanisch
    Erscheinungsdatum 2020-11-19
    Erscheinungsland Spain
    Dokumenttyp Editorial
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2020.11.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Probing the thermal resistance of solid-liquid interfaces in nanofluids with molecular dynamics.

    Carrillo-Berdugo, Iván / Navas, Javier / Grau-Crespo, Ricardo

    The Journal of chemical physics

    2024  Band 160, Heft 1

    Abstract: The significance of interfacial thermal resistance in the thermal conductivity of nanofluids is not well understood, in part because of the absence of measurements of this quantity. Here, we study the interfacial thermal resistance for metal-oil ... ...

    Abstract The significance of interfacial thermal resistance in the thermal conductivity of nanofluids is not well understood, in part because of the absence of measurements of this quantity. Here, we study the interfacial thermal resistance for metal-oil nanofluids of interest as heat transfer fluids for concentrating solar power, using density functional theory and molecular dynamics simulations. Insights on the role of chemical interactions in determining the interfacial thermal resistance are revealed. The results presented here showcase a general picture in which the stronger the chemical interactions between species at the interface, the lower the associated interfacial thermal resistance. The implications toward nanofluid design are discussed. We show that, for this important family of metal-oil nanofluids, the interfacial thermal resistance values are low enough so that it is possible to afford a reduction in particle size, minimizing stability and rheological issues while still offering enhancement in the effective thermal conductivity with respect to the base fluid.
    Sprache Englisch
    Erscheinungsdatum 2024-01-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0177616
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Protective Effect of Protocatechuic Acid on TNBS-Induced Colitis in Mice Is Associated with Modulation of the SphK/S1P Signaling Pathway

    Crespo, Irene / Mauriz, Jose L / González-Gallego, Javier

    Nutrients, 9(3):288

    2017  

    Abstract: 1) BACKGROUND: The present study aimed to investigate whether beneficial effects of protocatechuic acid (PCA) are associated with inhibition of the SphK/S1P axis and related signaling pathways in a 2,4,6-trinitrobenzenesulfonic acid (TNBS) model of ... ...

    Abstract (1) BACKGROUND: The present study aimed to investigate whether beneficial effects of protocatechuic acid (PCA) are associated with inhibition of the SphK/S1P axis and related signaling pathways in a 2,4,6-trinitrobenzenesulfonic acid (TNBS) model of inflammatory bowel disease; (2) METHODS: Colitis was induced in male Balb/c mice by intracolonic administration of 2 mg of TNBS. PCA (30 or 60 mg/kg body wt) was given intraperitoneally daily for five days; (3) RESULTS: Administration of PCA prevented the macroscopic and microscopic damage to the colonic mucosa, the decrease in body weight gain and the increase in myeloperoxidase activity induced by TNBS. PCA-treated mice exhibited a lower oxidized/reduced glutathione ratio, increased expression of antioxidant enzymes and Nrf2 and reduced expression of proinflammatory cytokines. Following TNBS treatment mRNA levels, protein concentration and immunohistochemical labelling for SphK1 increased significantly. S1P production and expression of S1P receptor 1 and S1P phosphatase 2 were significantly elevated. However, there was a decreased expression of S1P lyase. Furthermore, TNBS-treated mice exhibited increased phosphorylation of AKT and ERK, and a higher expression of pSTAT3 and the NF-κB p65 subunit. PCA administration significantly prevented those changes; (4) CONCLUSIONS: Data obtained suggest a contribution of the SphK/S1P system and related signaling pathways to the anti-inflammatory effect of PCA.
    Schlagwörter SphK/S1P signaling ; colitis ; inflammation ; sphingolipids ; protocatechuic acid
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  4. Artikel ; Online: Letter to the Editor: Updated guidance on NAFLD screening.

    Arias-Loste, María Teresa / Crespo, Javier / Iruzubieta, Paula

    Hepatology (Baltimore, Md.)

    2023  Band 78, Heft 5, Seite(n) E89–E90

    Mesh-Begriff(e) Humans ; Non-alcoholic Fatty Liver Disease/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2023-05-19
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1097/HEP.0000000000000462
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1660: Hefte anzeigen Standort:
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  5. Artikel: Technological, institutional, and geographical peripheries: regional development and risk of poverty in the European regions.

    Barbero, Javier / Rodríguez-Crespo, Ernesto

    The Annals of regional science

    2022  Band 69, Heft 2, Seite(n) 311–332

    Abstract: In this paper, we analyze the interrelation between technological, institutional, and geographical peripheries. By distinguishing between the quality and quantity of access to information and communication technologies, together with institutional and ... ...

    Abstract In this paper, we analyze the interrelation between technological, institutional, and geographical peripheries. By distinguishing between the quality and quantity of access to information and communication technologies, together with institutional and geographical factors, and using a sample of 229 European regions during the period 2007-2018, we find that the diffusion and quality of information and communication technologies foster economic development and decrease the risk of social exclusion. A similar effect is found for institutional and geographical factors, suggesting that the interplay of these three determinants may be crucial to set up place-based policies.
    Supplementary information: The online version contains supplementary material available at 10.1007/s00168-022-01127-9.
    Sprache Englisch
    Erscheinungsdatum 2022-04-02
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1471201-5
    ISSN 1432-0592 ; 0570-1864
    ISSN (online) 1432-0592
    ISSN 0570-1864
    DOI 10.1007/s00168-022-01127-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: A brief summary of endoscopic classifications in the upper gastrointestinal tract and their clinical relevance.

    Jiménez Sánchez, Javier / Delgado-Guillena, Pedro / Moreira, Leticia / Martínez Crespo, Juan José

    Gastroenterologia y hepatologia

    2024  Band 47, Heft 2, Seite(n) 194–198

    Mesh-Begriff(e) Humans ; Clinical Relevance ; Upper Gastrointestinal Tract/diagnostic imaging ; Endoscopy ; Endoscopy, Gastrointestinal
    Sprache Spanisch
    Erscheinungsdatum 2024-01-03
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 632502-6
    ISSN 0210-5705
    ISSN 0210-5705
    DOI 10.1016/j.gastrohep.2024.01.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Identifying the Enablers and Barriers to Advance Nurse Prescribing of Medication in Spain According to Experts' Views: A Delphi Study.

    Gomis-Jimeno, Francisco Javier / Lillo-Crespo, Manuel

    International journal of environmental research and public health

    2023  Band 20, Heft 6

    Abstract: Nurses play an important role in pharmaceutical care worldwide in detecting clinical changes, communicating and discussing pharmacotherapy with patients, their families, and other healthcare professionals, proposing and implementing drug-related ... ...

    Abstract Nurses play an important role in pharmaceutical care worldwide in detecting clinical changes, communicating and discussing pharmacotherapy with patients, their families, and other healthcare professionals, proposing and implementing drug-related interventions, and ensuring the monitoring of patients and their medication regimens, among others. However, there is no global consensus across countries regarding the prescribing of medication by nurses. In Spain, for example, this topic is currently in transition since the approval of the Royal Decree 1302/2018 of October 22nd, which regulates the indication, use, and authorization for dispensing human-use medication by nurses. Our study aims to identify the enablers and barriers to advancing the nurse prescribing of medication in Spain through the views of experts in the field and according to the latest Royal Decree approved and the steps taken by the different Spanish autonomous communities. A modified qualitative Delphi study with three iterations was performed online through the perspectives of experts from the field of healthcare education, research, practice, management, and policy. Data extracted from the literature review were used to formulate the open-ended questions utilized in the three rounds. The experts involved (n = 15) belonged to different Spanish regions where the Royal Decree is being implemented with different speeds, and had distinct backgrounds and experiences. Our results highlight the importance of prospectively developing additional protocols based on chronic diseases as well as scaling up towards independent nursing prescription, the inclusion of a joint multidisciplinary pharmaceutical care model, the controversial role played by national nursing councils and boards, the variability in the speed of implementation among the autonomous communities, and the lack of nursing training in the field of medication prescription.
    Mesh-Begriff(e) Humans ; Spain ; Delphi Technique ; Drug Prescriptions ; Health Personnel ; Delivery of Health Care
    Sprache Englisch
    Erscheinungsdatum 2023-03-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20064681
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Periprocedural management of hemostatic alterations in patients with cirrhosis and vascular liver disorders: a step forward of the American Association for the Study of Liver Diseases.

    Fortea, José Ignacio / Puente, Ángela / Crespo, Javier / Fábrega, Emilio

    Hepatobiliary surgery and nutrition

    2023  Band 12, Heft 1, Seite(n) 105–109

    Sprache Englisch
    Erscheinungsdatum 2023-01-16
    Erscheinungsland China (Republic : 1949- )
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-22-556
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Organic tracers in fine and coarse aerosols at an urban Mediterranean site: contribution of biomass burning and biogenic emissions.

    Clemente, Álvaro / Yubero, Eduardo / Nicolás, Jose F / Crespo, Javier / Galindo, Nuria

    Environmental science and pollution research international

    2024  Band 31, Heft 17, Seite(n) 25216–25226

    Abstract: The concentrations of anhydrosugars (levoglucosan, mannosan, and galactosan), polyols (inositol, xylitol, sorbitol, and mannitol), and glucose were measured in ... ...

    Abstract The concentrations of anhydrosugars (levoglucosan, mannosan, and galactosan), polyols (inositol, xylitol, sorbitol, and mannitol), and glucose were measured in PM
    Mesh-Begriff(e) Air Pollutants/analysis ; Particulate Matter/analysis ; Biomass ; Xylitol ; Aerosols/analysis ; Sorbitol ; Inositol ; Mannitol ; Environmental Monitoring/methods ; Seasons
    Chemische Substanzen Air Pollutants ; Particulate Matter ; Xylitol (VCQ006KQ1E) ; Aerosols ; Sorbitol (506T60A25R) ; Inositol (4L6452S749) ; Mannitol (3OWL53L36A)
    Sprache Englisch
    Erscheinungsdatum 2024-03-11
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32789-x
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    Verfügbar in ZB MED Bonn

    Z 5915: Hefte anzeigen

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  10. Artikel ; Online: Identifying the Enablers and Barriers to Advance Nurse Prescribing of Medication in Spain According to Experts’ Views

    Francisco Javier Gomis-Jimeno / Manuel Lillo-Crespo

    International Journal of Environmental Research and Public Health, Vol 20, Iss 4681, p

    A Delphi Study

    2023  Band 4681

    Abstract: Nurses play an important role in pharmaceutical care worldwide in detecting clinical changes, communicating and discussing pharmacotherapy with patients, their families, and other healthcare professionals, proposing and implementing drug-related ... ...

    Abstract Nurses play an important role in pharmaceutical care worldwide in detecting clinical changes, communicating and discussing pharmacotherapy with patients, their families, and other healthcare professionals, proposing and implementing drug-related interventions, and ensuring the monitoring of patients and their medication regimens, among others. However, there is no global consensus across countries regarding the prescribing of medication by nurses. In Spain, for example, this topic is currently in transition since the approval of the Royal Decree 1302/2018 of October 22nd, which regulates the indication, use, and authorization for dispensing human-use medication by nurses. Our study aims to identify the enablers and barriers to advancing the nurse prescribing of medication in Spain through the views of experts in the field and according to the latest Royal Decree approved and the steps taken by the different Spanish autonomous communities. A modified qualitative Delphi study with three iterations was performed online through the perspectives of experts from the field of healthcare education, research, practice, management, and policy. Data extracted from the literature review were used to formulate the open-ended questions utilized in the three rounds. The experts involved (n = 15) belonged to different Spanish regions where the Royal Decree is being implemented with different speeds, and had distinct backgrounds and experiences. Our results highlight the importance of prospectively developing additional protocols based on chronic diseases as well as scaling up towards independent nursing prescription, the inclusion of a joint multidisciplinary pharmaceutical care model, the controversial role played by national nursing councils and boards, the variability in the speed of implementation among the autonomous communities, and the lack of nursing training in the field of medication prescription.
    Schlagwörter nurse prescribing ; pharmaceutical care ; legislation ; Delphi study ; Medicine ; R
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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