LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU=Singh Sukhdev AU=Singh Sukhdev
  2. AU=Harman Katharine
  3. AU="Rosenbloom, Adam H"
  4. AU="Miyamato, Nobukazu"
  5. AU="Md. Yasir Arafat"
  6. AU="Nues, Paige"
  7. AU="Buhari, Shaik Ahmad"
  8. AU="Hamed, Kamal"
  9. AU="Bryan, R N"
  10. AU="Guo, Wanji"
  11. AU="Hermans, Philippe"
  12. AU="Jayaprakash Nattamai Subramanian"
  13. AU="Thorstensen, Matt J"
  14. AU="Konishi, Teruaki"
  15. AU="Jiang, Haiyue"
  16. AU="Kuznetsov, N S"
  17. AU=Rimmer Abi AU=Rimmer Abi
  18. AU="Zhou, Qinyao"
  19. AU="Taniguchi, Ryou"
  20. AU="Krauss, Thomas F"
  21. AU="Papoulidis, Ioannis"
  22. AU="Migaud, Henri"
  23. AU="Kelion, Andrew"
  24. AU="Harry Jabs"
  25. AU="Patel, Yatindra"
  26. AU="Aziza Jamal-Allial"
  27. AU="Montiel, Olga Martha"
  28. AU="Pérez Latorre, Leire"
  29. AU=Vardhan Seshu
  30. AU="OJ Baker"
  31. AU="Dalton, R C"
  32. AU="Mrozikiewicz-Rakowska, Beata"
  33. AU="Penkert, Judith"
  34. AU="Mak, Susanna"
  35. AU="Karkoszka, Henryk"
  36. AU="Burton, Jeffrey H"
  37. AU="Frederique Pitel"
  38. AU="Pierce, Aimee"
  39. AU="Luque-Ballesteros, Laura"
  40. AU="Dondi, Francesco"
  41. AU="McLachlan, Alex"
  42. AU="Krizova, Ludmila"
  43. AU="Balog, Attila"
  44. AU="Faerber, Karin"
  45. AU="Prettner, Klaus"
  46. AU="Ambrožová, I."
  47. AU="William, Doreen"
  48. AU="Gutiérrez-Sánchez, A M"
  49. AU="Bohan, Dana"
  50. AU="Spracklen, D."
  51. AU="Lobo, Brian C"
  52. AU=Zhuang Jianjian AU=Zhuang Jianjian
  53. AU=Pathanki Adithya M
  54. AU="Armando Vilchis-Ordoñez"
  55. AU="Zhongfu Lu"
  56. AU="Lo, Hong-Yip"
  57. AU="Ziman Xiong"
  58. AU="Oakes, Allison H"
  59. AU="Ma, Shaotong"
  60. AU="Zang, Lili"
  61. AU="Adams Brian D"
  62. AU="Maria Papaioannou"
  63. AU="Kollia, Georgia"
  64. AU="Auxiette, Catherine"
  65. AU="Guzmán, Luis"
  66. AU="Alipour, Elnaz"
  67. AU="Queiroz, Dayanna Joyce Marques"
  68. AU="Ramamurthy, Santosh"
  69. AU="Xueying Huang"
  70. AU="Cromwell, Howard C"
  71. AU="Spence, John C H"
  72. AU="Chapinal, Libertad"
  73. AU=Rohaim Mohammed A AU=Rohaim Mohammed A
  74. AU=Hempel Cornelius

Suchergebnis

Treffer 1 - 10 von insgesamt 161

Suchoptionen

  1. Artikel ; Online: Acute bilateral central serous chorioretinopathy in a young male after the first dose of Oxford/AstraZeneca AZD1222 (Covishield) vaccine.

    Sindhu, Meenakshi / Bamotra, Ravi Kant / Singh, Sukhdev

    Indian journal of ophthalmology

    2023  Band 71, Heft 2, Seite(n) 666–668

    Abstract: We case of acute bilateral central serous chorioretinopathy (CSCR) after receiving the first dose of Covishield vaccine in a young, otherwise healthy male with no associated risk factors. ...

    Abstract We case of acute bilateral central serous chorioretinopathy (CSCR) after receiving the first dose of Covishield vaccine in a young, otherwise healthy male with no associated risk factors.
    Mesh-Begriff(e) Humans ; Male ; ChAdOx1 nCoV-19 ; Central Serous Chorioretinopathy/diagnosis ; Acute Disease ; Risk Factors ; Visual Acuity
    Chemische Substanzen ChAdOx1 nCoV-19 (B5S3K2V0G8)
    Sprache Englisch
    Erscheinungsdatum 2023-06-01
    Erscheinungsland India
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1629_22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.B 329: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 598: Hefte anzeigen

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel: Regeneration of stem cuttings of pomegranate cv. bhagwa as influenced by pgr’s and planting time

    Kaur, Gurpreet / Singh, Sukhdev

    Agricultural science digest. 2022 Feb., v. 42, no. 1

    2022  

    Abstract: Pomegranate is being cultivated in the tropical and sub-tropical parts of the world for its delicious fruits. It can be propagated from seeds as well as from softwood, semi-hardwood and hardwood cuttings. The application of auxins encourages rooting in ... ...

    Abstract Pomegranate is being cultivated in the tropical and sub-tropical parts of the world for its delicious fruits. It can be propagated from seeds as well as from softwood, semi-hardwood and hardwood cuttings. The application of auxins encourages rooting in stem cutting owing to their ability to active cambium regeneration, cell division and cell multiplication. To meet the demand of pomegranate in the current situation and owing to its importance, the present study was undertaken. For regeneration of stem cuttings of pomegranate cv. Bhagwa as influenced by PGRs and planting time a study was conducted at the Department of Horticulture, Khalsa College, Amritsar during 2019-2020. The trial was undertaken with ten treatments comprising of IBA, PHB and NAA (500, 750 and 1000 ppm) each by quick dip method along with control planted in the first week of August and January. The results of the study revealed that IBA 1000 ppm (T₃) proved to be the best in terms of minimum days to first sprouting (11.06), maximum sprouting (91.10%), rooting (83.31%), number of roots per cutting (60.03), root length (11.55 cm), fresh weight of roots (1.08 g) and dry weight of roots (0.55 g). Among planting time the cuttings planted on first week of January proved to be effective in terms of sprouting (87.83%), survival (84.70%), rooting (78.81 %) and number of roots (52.06) respectively.
    Schlagwörter agricultural sciences ; cambium ; cell division ; hardwood ; pomegranates ; softwood
    Sprache Englisch
    Erscheinungsverlauf 2022-02
    Umfang p. 32-37.
    Erscheinungsort Agricultural Research Communication Centre
    Dokumenttyp Artikel
    ISSN 0976-0547
    DOI 10.18805/ag.D-5280
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel: Natural language processing: state of the art, current trends and challenges.

    Khurana, Diksha / Koli, Aditya / Khatter, Kiran / Singh, Sukhdev

    Multimedia tools and applications

    2022  , Seite(n) 1–32

    Abstract: Natural language processing (NLP) has recently gained much attention for representing and analyzing human language computationally. It has spread its applications in various fields such as machine translation, email spam detection, information extraction, ...

    Abstract Natural language processing (NLP) has recently gained much attention for representing and analyzing human language computationally. It has spread its applications in various fields such as machine translation, email spam detection, information extraction, summarization, medical, and question answering etc. In this paper, we first distinguish four phases by discussing different levels of NLP and components of
    Sprache Englisch
    Erscheinungsdatum 2022-07-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1479928-5
    ISSN 1573-7721 ; 1380-7501
    ISSN (online) 1573-7721
    ISSN 1380-7501
    DOI 10.1007/s11042-022-13428-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel ; Online: Lipopolysaccharide induced altered signaling pathways in various neurological disorders.

    Singh, Sukhdev / Sahu, Kuleshwar / Singh, Charan / Singh, Arti

    Naunyn-Schmiedeberg's archives of pharmacology

    2022  Band 395, Heft 3, Seite(n) 285–294

    Abstract: Neuroinflammation is defined as an inflammatory response within the brain or spinal cord, whereas the brain's innate immune system is triggered by various inflammatory challenges such as injury, infection, exposure to toxin (LPS) and ageing, which result ...

    Abstract Neuroinflammation is defined as an inflammatory response within the brain or spinal cord, whereas the brain's innate immune system is triggered by various inflammatory challenges such as injury, infection, exposure to toxin (LPS) and ageing, which result in cognitive impairment and neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). Lipopolysaccharide (LPS) is a main structural component of the outer membrane of gram-negative bacteria, widely used systematically to stimulate the immune system and to generate profound physiological and behavioural changes. It consists of three parts: lipid A, a core oligosaccharide and an O side chain. It is reported by several scientists that, besides the systemic alteration, LPS also induces neurodegeneration by promoting neuroinflammation upon binding with the stimulation of Toll-like receptor-4 (TLR4) receptors present on glial cells. The mammalian Toll-like receptor (TLR) family consists of 13 membranes and TLR was discovered as a crucial pattern recognition receptor (PPR) involved in the recognition of pathogen-associated molecular patterns (PAMPs). Future studies will show that damage/danger-associated molecular patterns (DAMPs) are recognised by the involvement of PPRs, generated by the host itself. The stimulation of TLR4 by lipopolysaccharide phosphorylates two signalling pathways, namely the MyD88-dependent pathway and the MyD88-independent pathway. This activation subsequently triggers the release of various pro-inflammatory cytokines that are necessary to activate innate immune responses, and then promotes neuroinflammation. In this review, we critically demonstrated the epidemiology of neuroinflammation, types of TLRs, the molecular mechanism of TLR4 and management of neuroinflammation.
    Mesh-Begriff(e) Animals ; Cytokines/metabolism ; Humans ; Lipopolysaccharides/toxicity ; Nervous System Diseases/physiopathology ; Neuroinflammatory Diseases/physiopathology ; Signal Transduction/physiology ; Toll-Like Receptor 4/metabolism ; Toll-Like Receptors/metabolism
    Chemische Substanzen Cytokines ; Lipopolysaccharides ; TLR4 protein, human ; Toll-Like Receptor 4 ; Toll-Like Receptors
    Sprache Englisch
    Erscheinungsdatum 2022-01-06
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Review
    ZDB-ID 121471-8
    ISSN 1432-1912 ; 0028-1298
    ISSN (online) 1432-1912
    ISSN 0028-1298
    DOI 10.1007/s00210-021-02198-9
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Ud II Zs.5: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  5. Artikel: An Analysis of Income and Consumption Pattern among Agricultural Labourer Households in Rural Punjab

    Sandhu, Sukhdev Singh / Toor, Jasdeep Singh

    Indian journal of ecology. 2022 Mar., v. 49, no. 1

    2022  

    Abstract: Pattern of income and consumption is an important parameter to study the economic conditions of people living in any society. The present analysis is based upon primary data which collected from three different agro-climate regions of Punjab (South-west, ...

    Abstract Pattern of income and consumption is an important parameter to study the economic conditions of people living in any society. The present analysis is based upon primary data which collected from three different agro-climate regions of Punjab (South-west, Central plain and Shivalik foot-hill). Income from casual activities in agricultural accounts more than 40 per cent of the total income for an average agricultural labourer household followed by permanent agricultural labour and non-farm employment in rural Punjab. South-west region has recorded the highest share of permanent agricultural labour income, while Central plain and Shivalik foot-hill region has recorded the highest share of casual agricultural labour income. The per capita income is the highest in South-west region of Punjab. In all regions, an average household spends higher proportion of total consumption on non-durable items followed by marriages & other socio-religious ceremonies, services and durable items. There are slightly a few point differences between the expenditure on education and intoxicants among the sampled households.
    Schlagwörter ecology ; education ; farm labor ; off-farm employment
    Sprache Englisch
    Erscheinungsverlauf 2022-03
    Umfang p. 295-301.
    Erscheinungsort Indian Ecological Society
    Dokumenttyp Artikel
    ZDB-ID 193796-0
    ISSN 0304-5250
    ISSN 0304-5250
    DOI 10.55362/IJE/2022/3520
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Bonn

    Z 7625: Hefte anzeigen

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  6. Artikel ; Online: A Review on the Neuroprotective Effect of Berberine against Chemotherapy- induced Cognitive Impairment.

    Sahu, Kuleshwar / Singh, Sukhdev / Devi, Bhawna / Singh, Charan / Singh, Arti

    Current drug targets

    2022  Band 23, Heft 9, Seite(n) 913–923

    Abstract: Chemobrain is one of the major side effects of chemotherapy; despite increased research, the mechanisms underlying chemotherapy-induced cognitive changes remain unknown. Several possibly important candidate mechanisms have been identified and will be ... ...

    Abstract Chemobrain is one of the major side effects of chemotherapy; despite increased research, the mechanisms underlying chemotherapy-induced cognitive changes remain unknown. Several possibly important candidate mechanisms have been identified and will be studied further in the future. Chemobrain is characterized by memory loss, cognitive impairment, difficulty in language, concentration, acceleration, and learning. The major characteristic of chemobrain is oxidative stress, mitochondrial dysfunction, immune dysregulation, hormonal alteration, white matter abnormalities, and DNA damage. Berberine (BBR) is an isoquinoline alkaloid extracted from various berberine species. BBR is a small chemical that easily passes the blood-brain barrier (BBB), making it useful for treating neurodegenerative diseases. Many studies on the pharmacology of BBR have been reported in the past. Furthermore, several clinical and experimental research indicates that BBR has a variety of pharmacological effects. So, in this review, we explore the pathogenesis of chemobrain and the neuroprotective potential of BBR against chemobrain. We also introduced the therapeutic role of BBR in various neurodegenerative and neurological diseases such as Alzheimer's, Parkinson's disease, mental depression, schizophrenia, anxiety, and also some stroke.
    Mesh-Begriff(e) Berberine/pharmacology ; Berberine/therapeutic use ; Chemotherapy-Related Cognitive Impairment ; Cognitive Dysfunction/chemically induced ; Cognitive Dysfunction/drug therapy ; Humans ; Neuroprotective Agents/adverse effects ; Oxidative Stress
    Chemische Substanzen Neuroprotective Agents ; Berberine (0I8Y3P32UF)
    Sprache Englisch
    Erscheinungsdatum 2022-03-03
    Erscheinungsland United Arab Emirates
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2064859-5
    ISSN 1873-5592 ; 1389-4501
    ISSN (online) 1873-5592
    ISSN 1389-4501
    DOI 10.2174/1389450123666220303094752
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5578: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  7. Artikel ; Online: Quercetin ameliorates lipopolysaccharide-induced neuroinflammation and oxidative stress in adult zebrafish.

    Singh, Sukhdev / Sahu, Kuleshwar / Kapil, Lakshay / Singh, Charan / Singh, Arti

    Molecular biology reports

    2022  Band 49, Heft 4, Seite(n) 3247–3258

    Abstract: Background: Quercetin is a natural flavonoid that is known to have numerous pharmacological activities such as antioxidative, anti-inflammatory, and neuroprotective effects against various neurological disorders. Lipopolysaccharide (LPS) is a potent ... ...

    Abstract Background: Quercetin is a natural flavonoid that is known to have numerous pharmacological activities such as antioxidative, anti-inflammatory, and neuroprotective effects against various neurological disorders. Lipopolysaccharide (LPS) is a potent endotoxin, reported causing several neurological disorders.
    Aim: The present study was designed to investigate the possibility that quercetin ameliorates LPS induced oxidative stress and neuroinflammation in adult zebrafish.
    Materials and methods: Zebrafish (weighing 470-530 mg) were treated with a single injection of LPS (1 mg/kg) intraperitoneally (i.p.) followed by post-treatment with quercetin (50 and 100 mg/kg; i.p.) for 7 days. After sacrificing brain was harvested and subjected for biochemical, molecular, and histological analyses.
    Results: Results revealed post-treatment with quercetin was able to ameliorate the behavioral abnormalities as in novel tank diving test- time spent in the top zone (TSTZ), and the number of entries in the top zone was significantly (p < 0.01) more as compared to time spent in the bottom zone (TSBZ). In the light-dark chamber test- time spent in the light zone (TSLZ), and the number of entries in the light zone were significantly (p < 0.01) more as compared to time spent in the dark compartment (TSDC). Additionally, results of histopathology (H & E stain) studies showed less disruption in neuronal cells as compared to the LPS treated group. Moreover, the results of the molecular analysis revealed that quercetin treatment significantly (p < 0.01) decrease TNF-α and IL-1β levels as compared to LPS treated animals. Further, results of the biochemical analysis reveal that quercetin significantly (p < 0.01) reduces the level of LPO, nitrite, AChEs and increases anti-oxidant GSH.
    Conclusion: Quercetin treatment helps to prevent oxidative damage and neuroinflammation in LPS treated adult zebrafish.
    Mesh-Begriff(e) Animals ; Inflammation/chemically induced ; Inflammation/drug therapy ; Lipopolysaccharides/toxicity ; Neuroinflammatory Diseases ; Oxidative Stress ; Quercetin/pharmacology ; Quercetin/therapeutic use ; Zebrafish
    Chemische Substanzen Lipopolysaccharides ; Quercetin (9IKM0I5T1E)
    Sprache Englisch
    Erscheinungsdatum 2022-01-30
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-022-07161-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1140: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  8. Artikel ; Online: Antilipase activity guided fractionation of Vinca major

    Sukhdev Singh / Singh Shamsher Kanwar

    Journal of King Saud University: Science, Vol 30, Iss 4, Pp 433-

    2018  Band 439

    Abstract: Methanolic extract of flowers of Vinca major (VFE) reduced the activity of porcine pancreatic lipase (PPL) which was reported in our previous study. To identify the antilipase molecule(s) in the VFE, the antilipase activity-guided fractionation for the ... ...

    Abstract Methanolic extract of flowers of Vinca major (VFE) reduced the activity of porcine pancreatic lipase (PPL) which was reported in our previous study. To identify the antilipase molecule(s) in the VFE, the antilipase activity-guided fractionation for the purification of lipase inhibitory molecule(s) by Silica Gel and Sephadex G-50 column chromatography was attempted, and the final anti-lipase fraction was examined by ESI-MS and FT-IR spectroscopy. Two molecules namely, Majoridine and Akuammine were elucidated to be present in the flowers of V. major which possessed high PPL inhibition activity. Further, both molecules were looked in silico for their interactions with PPL and other important proteins of lipid metabolism using molecular docking studies. Majoridine and Akuammine demonstrated significant binding interactions with active site residues of PPL. Keywords: Vinca major, Fractionation, ESI-MS, FT-IR, Majoridine, Akuammine, Docking
    Schlagwörter Science (General) ; Q1-390
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsdatum 2018-10-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  9. Artikel: Therapeutic effects of CoenzymeQ10, Biochanin A and Phloretin against arsenic and chromium induced oxidative stress in mouse (

    Tripathi, Swapnil / Fhatima, Shabrin / Parmar, Dharati / Singh, Dhirendra Pratap / Mishra, SukhDev / Mishra, Rajeev / Singh, Gyanendra

    3 Biotech

    2022  Band 12, Heft 5, Seite(n) 116

    Abstract: Arsenic and chromium are the most common environmental toxicants prevailing in nature. Hence, the present study endeavors to investigate the salutary effects of Coenzyme Q10 (CoQ10), Biochanin A (BCA), and Phloretin (PHL) on the combined neurotoxic ... ...

    Abstract Arsenic and chromium are the most common environmental toxicants prevailing in nature. Hence, the present study endeavors to investigate the salutary effects of Coenzyme Q10 (CoQ10), Biochanin A (BCA), and Phloretin (PHL) on the combined neurotoxic impact of arsenic and chromium in the
    Sprache Englisch
    Erscheinungsdatum 2022-04-21
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2600522-0
    ISSN 2190-5738 ; 2190-572X
    ISSN (online) 2190-5738
    ISSN 2190-572X
    DOI 10.1007/s13205-022-03171-w
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  10. Artikel: Quercetin ameliorates lipopolysaccharide-induced neuroinflammation and oxidative stress in adult zebrafish

    Singh, Sukhdev / Sahu, Kuleshwar / Kapil, Lakshay / Singh, Charan / Singh, Arti

    Molecular biology reports. 2022 Apr., v. 49, no. 4

    2022  

    Abstract: BACKGROUND: Quercetin is a natural flavonoid that is known to have numerous pharmacological activities such as antioxidative, anti-inflammatory, and neuroprotective effects against various neurological disorders. Lipopolysaccharide (LPS) is a potent ... ...

    Abstract BACKGROUND: Quercetin is a natural flavonoid that is known to have numerous pharmacological activities such as antioxidative, anti-inflammatory, and neuroprotective effects against various neurological disorders. Lipopolysaccharide (LPS) is a potent endotoxin, reported causing several neurological disorders. AIM: The present study was designed to investigate the possibility that quercetin ameliorates LPS induced oxidative stress and neuroinflammation in adult zebrafish. MATERIALS AND METHODS: Zebrafish (weighing 470–530 mg) were treated with a single injection of LPS (1 mg/kg) intraperitoneally (i.p.) followed by post-treatment with quercetin (50 and 100 mg/kg; i.p.) for 7 days. After sacrificing brain was harvested and subjected for biochemical, molecular, and histological analyses. RESULTS: Results revealed post-treatment with quercetin was able to ameliorate the behavioral abnormalities as in novel tank diving test- time spent in the top zone (TSTZ), and the number of entries in the top zone was significantly (p < 0.01) more as compared to time spent in the bottom zone (TSBZ). In the light–dark chamber test- time spent in the light zone (TSLZ), and the number of entries in the light zone were significantly (p < 0.01) more as compared to time spent in the dark compartment (TSDC). Additionally, results of histopathology (H & E stain) studies showed less disruption in neuronal cells as compared to the LPS treated group. Moreover, the results of the molecular analysis revealed that quercetin treatment significantly (p < 0.01) decrease TNF-α and IL-1β levels as compared to LPS treated animals. Further, results of the biochemical analysis reveal that quercetin significantly (p < 0.01) reduces the level of LPO, nitrite, AChEs and increases anti-oxidant GSH. CONCLUSION: Quercetin treatment helps to prevent oxidative damage and neuroinflammation in LPS treated adult zebrafish.
    Schlagwörter Danio rerio ; adults ; antioxidants ; brain ; endotoxins ; histology ; histopathology ; lipopolysaccharides ; molecular biology ; neurons ; nitrites ; oxidative stress ; quercetin
    Sprache Englisch
    Erscheinungsverlauf 2022-04
    Umfang p. 3247-3258.
    Erscheinungsort Springer Netherlands
    Dokumenttyp Artikel
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-022-07161-2
    Datenquelle NAL Katalog (AGRICOLA)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Bonn

    Z 78/728: Hefte anzeigen

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang