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  1. Artikel ; Online: Genome sequence, antibiotic resistance genes, and plasmids in a monophasic variant of

    Ghorbani Tajani, Anahita / Sharma, Aniket / Blouin, Nicolas / Bisha, Bledar

    Microbiology resource announcements

    2024  , Seite(n) e0075423

    Abstract: ... ...

    Abstract A
    Sprache Englisch
    Erscheinungsdatum 2024-05-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2576-098X
    ISSN (online) 2576-098X
    DOI 10.1128/mra.00754-23
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  2. Artikel ; Online: Interplay between α-synuclein and parkin genes: Insights of Parkinson's disease.

    Sharma, Kajal / Chib, Shivani / Gupta, Aniket / Singh, Randhir / Chalotra, Rishabh

    Molecular biology reports

    2024  Band 51, Heft 1, Seite(n) 586

    Abstract: Parkinson's disease (PD) is a complex and debilitating neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. The pathogenesis of PD is intimately linked to the roles of two key molecular players, ...

    Abstract Parkinson's disease (PD) is a complex and debilitating neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra. The pathogenesis of PD is intimately linked to the roles of two key molecular players, α-synuclein (α-syn) and Parkin. Understanding the intricate interplay between α-syn and Parkin is essential for unravelling the molecular underpinnings of PD. Their roles in synaptic function and protein quality control underscore their significance in neuronal health. Dysregulation of these processes, as seen in PD, highlights the potential for targeted therapeutic strategies aimed at restoring normal protein homeostasis and mitigating neurodegeneration. Investigating the connections between α-syn, Parkin, and various pathological mechanisms provides insights into the complex web of factors contributing to PD pathogenesis and offers hope for the development of more effective treatments for this devastating neurological disorder. The present compilation provides an overview of their structures, regional and cellular locations, associations, physiological functions, and pathological roles in the context of PD.
    Mesh-Begriff(e) Parkinson Disease/genetics ; Parkinson Disease/metabolism ; alpha-Synuclein/genetics ; alpha-Synuclein/metabolism ; Humans ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism ; Animals ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/pathology
    Chemische Substanzen alpha-Synuclein ; parkin protein (EC 2.3.2.27) ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Review
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-024-09520-7
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  3. Buch ; Online: Nash Equilibria of Two-Player Matrix Games Repeated Until Collision

    Murhekar, Aniket / Sharma, Eklavya

    2023  

    Abstract: We introduce and initiate the study of a natural class of repeated two-player matrix games, called Repeated-Until-Collision (RUC) games. In each round, both players simultaneously pick an action from a common action set $\{1, 2, \dots, n\}$. Depending on ...

    Abstract We introduce and initiate the study of a natural class of repeated two-player matrix games, called Repeated-Until-Collision (RUC) games. In each round, both players simultaneously pick an action from a common action set $\{1, 2, \dots, n\}$. Depending on their chosen actions, they derive payoffs given by $n \times n$ matrices $A$ and $B$, respectively. If their actions collide (i.e., they pick the same action), the game ends, otherwise, it proceeds to the next round. Both players want to maximize their total payoff until the game ends. RUC games can be interpreted as pursuit-evasion games or repeated hide-and-seek games. They also generalize hand cricket, a popular game among children in India. We show that under mild assumptions on the payoff matrices, every RUC game admits a Nash equilibrium (NE). Moreover, we show the existence of a stationary NE, where each player chooses their action according to a probability distribution over the action set that does not change across rounds. Remarkably, we show that all NE are effectively the same as the stationary NE, thus showing that RUC games admit an almost unique NE. Lastly, we also show how to compute (approximate) NE for RUC games.

    Comment: Accepted to FSTTCS 2023
    Schlagwörter Computer Science - Computer Science and Game Theory
    Thema/Rubrik (Code) 700
    Erscheinungsdatum 2023-09-26
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Decoding the therapeutic landscape of alpha-linolenic acid: a network pharmacology and bioinformatics investigation against cancer-related epigenetic modifiers.

    Ulhe, Amrita / Sharma, Nidhi / Mahajan, Akanksha / Patil, Rajesh / Hegde, Mahabaleshwar / Bhalerao, Supriya / Mali, Aniket

    Journal of biomolecular structure & dynamics

    2023  , Seite(n) 1–26

    Abstract: Omega-3 ( ...

    Abstract Omega-3 (
    Sprache Englisch
    Erscheinungsdatum 2023-12-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2293267
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  5. Buch ; Online: Decentralized Aerial Transportation and Manipulation of a Cable-Slung Payload With Swarm of Agents

    Sharma, Aniket / Sinha, Nandan K

    2023  

    Abstract: With the advent of Unmanned Aerial Vehicles (UAV) and Micro Aerial Vehicles (MAV) in commercial sectors, their application for transporting and manipulating payloads has attracted many research work. A swarm of agents, cooperatively working to transport ... ...

    Abstract With the advent of Unmanned Aerial Vehicles (UAV) and Micro Aerial Vehicles (MAV) in commercial sectors, their application for transporting and manipulating payloads has attracted many research work. A swarm of agents, cooperatively working to transport and manipulate a payload can overcome the physical limitations of a single agent, adding redundancy and tolerance against failures. In this paper, the dynamics of a swarm connected to a payload via flexible cables are modeled, and a decentralized control is designed using Artificial Potential Field (APF). The swarm is able to transport the payload through an unknown environment to a goal position while avoiding obstacles from the local information received from the onboard sensors. The key contributions are (a) the cables are modelled more accurately using lumped mass model instead of geometric constraints, (b) a decentralized swarm control is designed using potential field approach to ensure hover stability of system without payload state information, (c) the manipulation of payload elevation and azimuth angles are controlled by APF, and (d) the trajectory of the payload for transportation is governed by potential fields generated by goal point and obstacles. The efficacy of the method proposed in this work are evaluated through numerical simulations under the influence of external disturbances and failure of agents.
    Schlagwörter Computer Science - Multiagent Systems ; Computer Science - Robotics
    Thema/Rubrik (Code) 629
    Erscheinungsdatum 2023-06-21
    Erscheinungsland us
    Dokumenttyp Buch ; Online
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  6. Artikel ; Online: Emergence of lumpy skin disease virus (LSDV) infection in domestic Himalayan yaks (Bos grunniens) in Himachal Pradesh, India.

    Sudhakar, Shashi Bhushan / Mishra, Niranjan / Kalaiyarasu, Semmannan / Sharma, Ram Krishan / Ahirwar, Khusboo / Vashist, Vikram S / Agarwal, Sonam / Sanyal, Aniket

    Archives of virology

    2024  Band 169, Heft 3, Seite(n) 51

    Abstract: In this study, we investigated and confirmed natural lumpy skin disease virus (LSDV) infection in Himalayan yaks (Bos grunniens) in Himachal Pradesh, India, based on clinical manifestations and results of genome detection, antibody detection, virus ... ...

    Abstract In this study, we investigated and confirmed natural lumpy skin disease virus (LSDV) infection in Himalayan yaks (Bos grunniens) in Himachal Pradesh, India, based on clinical manifestations and results of genome detection, antibody detection, virus isolation, and nucleotide sequencing. Subsequent phylogenetic analysis based on complete GPCR, RPO30, and EEV gene sequences revealed that the LSDV isolates from these yaks and local cattle belonged to LSDV subcluster 1.2.1 rather than the dominant subcluster 1.2.2, which is currently circulating in India, suggesting a separate recent introduction. This is the first report of natural LSDV infection in yaks in India, expanding the known host range of LSDV. Further investigations are needed to assess the impact of LSDV infection in yaks.
    Mesh-Begriff(e) Animals ; Cattle ; Lumpy skin disease virus ; Phylogeny ; Base Sequence ; India/epidemiology ; Disease Outbreaks/veterinary
    Sprache Englisch
    Erscheinungsdatum 2024-02-20
    Erscheinungsland Austria
    Dokumenttyp Journal Article
    ZDB-ID 7491-3
    ISSN 1432-8798 ; 0304-8608
    ISSN (online) 1432-8798
    ISSN 0304-8608
    DOI 10.1007/s00705-024-05994-9
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  7. Artikel ; Online: Defect mediated improved charge carrier dynamics in hybrid bulk-heterojunction solar cell induced by phase pure iron pyrite nanocubes.

    Sharma, Punit / Rana, Aniket / Waheed, Sobia / Pareek, Saurabh / Karak, Supravat

    Nanotechnology

    2021  Band 32, Heft 26

    Abstract: In this article, the synthesis of phase pure iron pyrite nanocubes ( ... ...

    Abstract In this article, the synthesis of phase pure iron pyrite nanocubes (FeS
    Sprache Englisch
    Erscheinungsdatum 2021-04-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/abe1f2
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  8. Artikel ; Online: Restoring Teeth Aids in Restoring Identity- Role of Restorative Dentistry in Forensic Odontology

    Hrishita Majumder / Anupam Sandeep Sharma / Aniket Jadhav / Sushmita Sudarshan Deshpande / Manali Suresh Kadam

    Journal of Clinical and Diagnostic Research, Vol 17, Iss 4, Pp ZE08-ZE

    2023  Band 12

    Abstract: Forensic odontology is a relatively new branch in the field of dentistry that has opened a new horizon for many dentists. With a surge of crime rates and lawsuits in the world, the need for specialists to help in identification of post mortem remains has ...

    Abstract Forensic odontology is a relatively new branch in the field of dentistry that has opened a new horizon for many dentists. With a surge of crime rates and lawsuits in the world, the need for specialists to help in identification of post mortem remains has increased. The reason for forensic odontology as an up-and-coming field in recent times is because teeth and the surrounding orofacial structures, similar to fingerprints, are unique features and can be used for definitive identification. This uniqueness can be attributed to variations in morphology, size and different treatment history of every individual. Teeth are a good source of data for post mortem studies as they are durable structures and are able to resist decomposition. For this reason, forensic odontology has become a promising field in recent times. Materials used to restore teeth have also shown durability in adverse conditions and increase the variations that can help in identification as restorations can be considered as unique features. The aim of this review article is to describe the various ways restorative materials can aid in identification of individuals.
    Schlagwörter dental records ; dental restoration ; forensic science ; victim identification ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2023-04-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
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  9. Artikel ; Online: Mortality of in-hospital cardiac arrest among patients with and without preceding sepsis: A national inpatient sample analysis.

    Hasegawa, Daisuke / Sharma, Aniket / Dugar, Siddharth / Lee, Young Im / Sato, Ryota

    Journal of critical care

    2023  Band 78, Seite(n) 154404

    Abstract: Introduction: The impact of preceding sepsis on in-hospital cardiac arrest (IHCA)-related mortality has not been established. This study aimed to determine the association between IHCA-related mortality and sepsis.: Methods: This retrospective study ... ...

    Abstract Introduction: The impact of preceding sepsis on in-hospital cardiac arrest (IHCA)-related mortality has not been established. This study aimed to determine the association between IHCA-related mortality and sepsis.
    Methods: This retrospective study used the National Inpatient Sample data from 01/2017 to 12/2019. The study included adults (≥18 years) who suffered from IHCA. The study classified cardiac arrest rhythms as ventricular tachycardia/ventricular fibrillation or pulseless electronic activity/asystole. We compared the IHCA-related in-hospital mortality between sepsis and non-sepsis groups in all patients and subgroups divided by cardiac arrest rhythm and age. Multivariable logistic regression analysis was performed to assess the independent association between sepsis and in-hospital mortality.
    Results: A total of 357,850 hospitalizations who suffered from IHCA were identified, with sepsis present in 17.6% of patients. IHCA-related in-hospital mortality was 84.8% in sepsis and 68.4% in non-sepsis-related hospitalizations (p < 0.001). IHCA-related in-hospital mortality was higher in sepsis than in non-sepsis groups, regardless of age or cardiac arrest rhythms. In multivariable logistic regression analysis, sepsis was significantly associated with higher mortality with an odds ratio of 2.27 (95% confidence interval: 2.07-2.50, p < 0.001).
    Conclusion: Sepsis was associated with higher in-hospital cardiac arrest mortality compared to non-sepsis cases, regardless of age and cardiac rhythm.
    Mesh-Begriff(e) Adult ; Humans ; Inpatients ; Retrospective Studies ; Heart Arrest ; Hospital Mortality ; Sepsis/complications ; Ventricular Fibrillation ; Hospitals
    Sprache Englisch
    Erscheinungsdatum 2023-08-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2023.154404
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  10. Artikel ; Online: Adapting model-based deep learning to multiple acquisition conditions: Ada-MoDL.

    Pramanik, Aniket / Bhave, Sampada / Sajib, Saurav / Sharma, Samir D / Jacob, Mathews

    Magnetic resonance in medicine

    2023  Band 90, Heft 5, Seite(n) 2033–2051

    Abstract: Purpose: The aim of this work is to introduce a single model-based deep network that can provide high-quality reconstructions from undersampled parallel MRI data acquired with multiple sequences, acquisition settings, and field strengths.: Methods: A ...

    Abstract Purpose: The aim of this work is to introduce a single model-based deep network that can provide high-quality reconstructions from undersampled parallel MRI data acquired with multiple sequences, acquisition settings, and field strengths.
    Methods: A single unrolled architecture, which offers good reconstructions for multiple acquisition settings, is introduced. The proposed scheme adapts the model to each setting by scaling the convolutional neural network (CNN) features and the regularization parameter with appropriate weights. The scaling weights and regularization parameter are derived using a multilayer perceptron model from conditional vectors, which represents the specific acquisition setting. The perceptron parameters and the CNN weights are jointly trained using data from multiple acquisition settings, including differences in field strengths, acceleration, and contrasts. The conditional network is validated using datasets acquired with different acquisition settings.
    Results: The comparison of the adaptive framework, which trains a single model using the data from all the settings, shows that it can offer consistently improved performance for each acquisition condition. The comparison of the proposed scheme with networks that are trained independently for each acquisition setting shows that it requires less training data per acquisition setting to offer good performance.
    Conclusion: The Ada-MoDL framework enables the use of a single model-based unrolled network for multiple acquisition settings. In addition to eliminating the need to train and store multiple networks for different acquisition settings, this approach reduces the training data needed for each acquisition setting.
    Mesh-Begriff(e) Deep Learning ; Neural Networks, Computer ; Magnetic Resonance Imaging ; Image Processing, Computer-Assisted
    Sprache Englisch
    Erscheinungsdatum 2023-06-18
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 605774-3
    ISSN 1522-2594 ; 0740-3194
    ISSN (online) 1522-2594
    ISSN 0740-3194
    DOI 10.1002/mrm.29750
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