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  1. Artikel ; Online: High-flow nasal cannula in Spanish Pediatric Intensive Care Services: A national web survey about its use and indications.

    García-Salido, Alberto / Modesto I Alapont, Vicente / Medina-Villanueva, Alberto

    Medicina intensiva

    2024  

    Abstract: Objective: To describe the high-flow nasal cannula (HFNC) indications in the Spanish pediatric critical care units (PICUs).: Design: Descriptive cross-sectional observational study.: Setting: Electronic survey among members of the Spanish Society ... ...

    Abstract Objective: To describe the high-flow nasal cannula (HFNC) indications in the Spanish pediatric critical care units (PICUs).
    Design: Descriptive cross-sectional observational study.
    Setting: Electronic survey among members of the Spanish Society of Pediatric Intensive Care (SECIP). It was sent weekly from April 10, 2023, to May 21, 2023.
    Participants: All SECIP members.
    Interventions: None.
    Main variables of interest: The questions focused on workplace, years of experience, use or non-use of HFNC, justification and expectations regarding its application, starting point within each center, clinical criteria for indication, existence of clinical guidelines, evaluation during its use, and criteria and mode of withdrawal.
    Results: Two hundred and two participants, 176 were from Spain. Of these, 87/176 had over ten years of experience. One hundred sixty two use HFNC and 66/162 have HFNC clinical guidelines. Acute bronchiolitis (138/162) and respiratory assistance after extubation (106/56) are the two main indications. For 62/162 HFNC may reduce therapeutic escalation. Neuromuscular diseases (105/162) and anatomical airway diseases (135/162) are the two main contraindications. The reasons to do not use HFNC were the absence of evidence about it effectiveness (8/14) and its inadequate cost/effectiveness balance (8/14).
    Conclusions: A majority of Spanish pediatric intensivists use HFNC. Its application and withdrawal appears to be primarily based on clinical experience. Besides, those who use HFNC are aware of its limitations and the lack of evidence in some cases. It is necessary to develop single-center and multicenter studies to elucidate the effectiveness of this therapy in the context of critically ill children.
    Sprache Englisch
    Erscheinungsdatum 2024-04-25
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ISSN 2173-5727
    ISSN (online) 2173-5727
    DOI 10.1016/j.medine.2024.03.012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Three Hypotheses About Children COVID19.

    García-Salido, Alberto

    The Pediatric infectious disease journal

    2020  Band 39, Heft 7, Seite(n) e157

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-11
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000002701
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: SARS-CoV-2 children transmission: The evidence is that today we do not have enough evidence.

    García-Salido, Alberto

    Acta paediatrica (Oslo, Norway : 1992)

    2020  Band 109, Heft 9, Seite(n) 1912

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; Child ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-07-06
    Erscheinungsland Norway
    Dokumenttyp Letter ; Comment
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.15396
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Revisión narrativa sobre la respuesta inmunitaria frente a coronavirus: descripción general, aplicabilidad para SARS-COV-2 e implicaciones terapéuticas.

    García-Salido, Alberto

    Anales de pediatria

    2020  Band 93, Heft 1, Seite(n) 60.e1–60.e7

    Abstract: The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health ... ...

    Titelübersetzung Narrative review of the immune response against coronavirus: An overview, applicability for SARS-COV-2, and therapeutic implications.
    Abstract The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health emergency by the World Health Organisation. This new SARS-CoV-2 virus could share characteristics and an immune response similar to those described for other coronavirus. Given its activity on the interferon pathway, and the manner in which it dysregulates innate immunity, the use of treatments directed at modulating or containing this could be of interest. A narrative review was made of the current evidence about immunity against coronavirus and its applicability to SARS-CoV-2. The physiopathogenesis is also described, along with the underlying leucocyte activity, with the intention of clarifying the possible usefulness of inflammatory biomarkers and the development of personalised treatments.
    Mesh-Begriff(e) Betacoronavirus/immunology ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Global Health ; Humans ; Immunity, Innate/immunology ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Public Health ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Spanisch
    Erscheinungsdatum 2020-04-25
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpedi.2020.04.016
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Narrative review of the immune response against coronavirus: An overview, applicability for SARS-COV-2, and therapeutic implications.

    García-Salido, Alberto

    Anales de pediatria

    2020  Band 93, Heft 1, Seite(n) 60.e1–60.e7

    Abstract: The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health ... ...

    Abstract The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health emergency by the World Health Organisation. This new SARS-CoV-2 virus could share characteristics and an immune response similar to those described for other coronavirus. Given its activity on the interferon pathway, and the manner in which it dysregulates innate immunity, the use of treatments directed at modulating or containing this could be of interest. A narrative review was made of the current evidence about immunity against coronavirus and its applicability to SARS-CoV-2. The physiopathogenesis is also described, along with the underlying leucocyte activity, with the intention of clarifying the possible usefulness of inflammatory biomarkers and the development of personalised treatments.
    Sprache Englisch
    Erscheinungsdatum 2020-06-08
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpede.2020.04.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Three Hypotheses About Children COVID19

    García-Salido, Alberto

    Pediatric Infectious Disease Journal

    2020  Band Publish Ahead of Print

    Schlagwörter Pediatrics, Perinatology, and Child Health ; Microbiology (medical) ; Infectious Diseases ; covid19
    Sprache Englisch
    Verlag Ovid Technologies (Wolters Kluwer Health)
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/inf.0000000000002701
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: SARS‐CoV‐2 children transmission

    García-Salido, Alberto

    Acta Paediatrica

    The evidence is that today we do not have enough evidence

    2020  Band 109, Heft 9, Seite(n) 1912–1912

    Schlagwörter Pediatrics, Perinatology, and Child Health ; General Medicine ; covid19
    Sprache Englisch
    Verlag Wiley
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ISSN 0803-5253
    DOI 10.1111/apa.15396
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel: Revisión narrativa sobre la respuesta inmunitaria frente a coronavirus: descripción general, aplicabilidad para SARS-COV-2 e implicaciones terapéuticas./ [Narrative review of the immune response against coronavirus: An overview, applicability for SARS-COV-2, and therapeutic implications]

    García-Salido, Alberto

    An. pediatr. (2003. Ed. impr.)

    Abstract: The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health ... ...

    Abstract The new coronavirus (SARS-CoV-2) that causes a severe acute respiratory syndrome emerges in Wuhan, China, in December 2019. It produces the aforementioned disease due to coronavirus 2019 (COVID-19), and has led to a declaration of a world public health emergency by the World Health Organisation. This new SARS-CoV-2 virus could share characteristics and an immune response similar to those described for other coronavirus. Given its activity on the interferon pathway, and the manner in which it dysregulates innate immunity, the use of treatments directed at modulating or containing this could be of interest. A narrative review was made of the current evidence about immunity against coronavirus and its applicability to SARS-CoV-2. The physiopathogenesis is also described, along with the underlying leucocyte activity, with the intention of clarifying the possible usefulness of inflammatory biomarkers and the development of personalised treatments.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32439309
    Datenquelle COVID19

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