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  1. Artikel: Place in Therapy of the Newly Available Armamentarium for Multi-Drug-Resistant Gram-Negative Pathogens: Proposal of a Prescription Algorithm.

    Volpicelli, Lorenzo / Venditti, Mario / Ceccarelli, Giancarlo / Oliva, Alessandra

    Antibiotics (Basel, Switzerland)

    2021  Band 10, Heft 12

    Abstract: The worldwide propagation of antimicrobial resistance represents one of the biggest threats to global health and development. Multi-drug-resistant organisms (MDROs), including carbapenem-resistant non-fermenting Gram-negatives ... ...

    Abstract The worldwide propagation of antimicrobial resistance represents one of the biggest threats to global health and development. Multi-drug-resistant organisms (MDROs), including carbapenem-resistant non-fermenting Gram-negatives and
    Sprache Englisch
    Erscheinungsdatum 2021-11-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics10121475
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: What are the treatment options for resistant

    Spaziante, Martina / Oliva, Alessandra / Ceccarelli, Giancarlo / Venditti, Mario

    Expert opinion on pharmacotherapy

    2020  Band 21, Heft 15, Seite(n) 1781–1787

    Sprache Englisch
    Erscheinungsdatum 2020-06-17
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2020.1779221
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  3. Artikel: Occupational Risk for Coronary Artery Disease in Shift Workers - A Systematic Review.

    D'Ettorre, Gabriele / Piscitelli, Prisco / Pellicani, Vincenza / Tornese, Roberta / Ceccarelli, Giancarlo / D'Ettorre, Gabriella / La Torre, Giuseppe

    La Medicina del lavoro

    2024  Band 115, Heft 2, Seite(n) e2024015

    Abstract: Background: Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, ...

    Abstract Background: Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, the pathogenic mechanism between shift work and CAD to date is unclear. This systematic review aims to enhance understanding of the risk of CAD occurrence in SWs.
    Methods: A systematic literature review was conducted from January 2013 to December 2023. MEDLINE/Pubmed databases were used initially, and additional relevant studies were searched from references. Shift work was defined as any schedule outside traditional shifts, including the night shift.
    Results: Fifteen pertinent papers were categorized into risk assessment or risk management. Findings demonstrated an increased risk of CAD among SWs compared to non-SWs, with an increased CAD risk observed for both shift work and night shift work.
    Discussion: Duration-response associations indicate that greater shift exposure is linked to higher CAD risk. SWs incur an increased risk of CAD through the atherosclerotic process. As shift work duration increases as the risk of atherosclerosis is higher, workers demonstrate a higher prevalence and severity of coronary artery plaques.
    Conclusions: The evidence-based results underscore the increased risk of CAD in SWs and are sufficient for proposing guidelines aimed at reducing the risk of CAD in SWs and at managing people with CAD in return to work characterized by disrupted circadian rhythms.
    Mesh-Begriff(e) Humans ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/etiology ; Shift Work Schedule/adverse effects ; Occupational Diseases/epidemiology ; Occupational Diseases/etiology ; Risk Factors ; Risk Assessment ; Work Schedule Tolerance
    Sprache Englisch
    Erscheinungsdatum 2024-04-24
    Erscheinungsland Italy
    Dokumenttyp Systematic Review ; Journal Article
    ZDB-ID 123678-7
    ISSN 0025-7818
    ISSN 0025-7818
    DOI 10.23749/mdl.v115i2.15532
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Dysbiosis in SARS-CoV-2-Infected Patients.

    Marazzato, Massimiliano / Ceccarelli, Giancarlo / d'Ettorre, Gabriella

    Gastroenterology

    2020  Band 160, Heft 6, Seite(n) 2195

    Mesh-Begriff(e) COVID-19 ; Dysbiosis ; Hospitalization ; Humans ; Mycobiome ; Patient Discharge ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2020-12-30
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.12.056
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  5. Artikel ; Online: Early recognition of a superinfection: This is the problem in the critically ill COVID-19 patients.

    Alessandri, Francesco / d'Ettorre, Gabriella / Ciccozzi, Massimo / Migliara, Giuseppe / Baccolini, Valentina / Pugliese, Francesco / Ceccarelli, Giancarlo

    Journal of medical virology

    2023  Band 96, Heft 1, Seite(n) e29345

    Mesh-Begriff(e) Humans ; COVID-19/diagnosis ; Critical Illness ; Superinfection/diagnosis ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2023-12-26
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29345
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  6. Artikel ; Online: Infection prevention and control programme and COVID-19 measures: Effects on hospital-acquired infections in patients with cirrhosis.

    Di Cola, Simone / Gazda, Jakub / Lapenna, Lucia / Ceccarelli, Giancarlo / Merli, Manuela

    JHEP reports : innovation in hepatology

    2023  Band 5, Heft 5, Seite(n) 100703

    Abstract: Background & aims: Bacterial infections affect survival of patients with cirrhosis. Hospital-acquired bacterial infections present a growing healthcare problem because of the increasing prevalence of multidrug-resistant organisms. This study aimed to ... ...

    Abstract Background & aims: Bacterial infections affect survival of patients with cirrhosis. Hospital-acquired bacterial infections present a growing healthcare problem because of the increasing prevalence of multidrug-resistant organisms. This study aimed to investigate the impact of an infection prevention and control programme and coronavirus disease 2019 (COVID-19) measures on the incidence of hospital-acquired infections and a set of secondary outcomes, including the prevalence of multidrug-resistant organisms, empiric antibiotic treatment failure, and development of septic states in patients with cirrhosis.
    Methods: The infection prevention and control programme was a complex strategy based on antimicrobial stewardship and the reduction of patient's exposure to risk factors. The COVID-19 measures presented further behavioural and hygiene restrictions imposed by the Hospital and Health Italian Sanitary System recommendations. We performed a combined retrospective and prospective study in which we compared the impact of extra measures against the hospital standard.
    Results: We analysed data from 941 patients. The infection prevention and control programme was associated with a reduction in the incidence of hospital-acquired infections (17
    Conclusions: The infection prevention and control programme decreased the incidence of hospital-acquired infections by nearly 50%. Furthermore, the programme also reduced the prevalence of most of the secondary outcomes. Based on the results of this study, we encourage other liver centres to adopt infection prevention and control programmes.
    Impact and implications: Infections are a life-threatening problem for patients with liver cirrhosis. Moreover, hospital-acquired infections are even more alarming owing to the high prevalence of multidrug-resistant bacteria. This study analysed a large cohort of hospitalised patients with cirrhosis from three different periods. Unlike in the first period, an infection prevention programme was applied in the second period, reducing the number of hospital-acquired infections and containing multidrug-resistant bacteria. In the third period, we imposed even more stringent measures to minimise the impact of the COVID-19 outbreak. However, these measures did not result in a further reduction in hospital-acquired infections.
    Sprache Englisch
    Erscheinungsdatum 2023-02-19
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2589-5559
    ISSN (online) 2589-5559
    DOI 10.1016/j.jhepr.2023.100703
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  7. Artikel ; Online: Occupational health surveillance of healthcare workers during COVID 19 pandemic: a narrative review.

    D'Ettorre, Gabriele / Pellicani, Vincenza / Muratore, Massimo / Ceccarelli, Giancarlo

    Acta bio-medica : Atenei Parmensis

    2022  Band 93, Heft 1, Seite(n) e2022007

    Abstract: Background and aims: Current literature has increasingly highlighted the risk of spreading the SARS-COV-2 infection in healthcare settings and showed the need for occupational health surveillance of HCWs during the current epidemiological emergency from ...

    Abstract Background and aims: Current literature has increasingly highlighted the risk of spreading the SARS-COV-2 infection in healthcare settings and showed the need for occupational health surveillance of HCWs during the current epidemiological emergency from COVID-19, as a preventive measure to minimize the spread of the infection. The purpose of this narrative review was to evaluate the literature and discover what the latest developments are about the management of the occupational health surveillance of healthcare workers (HCWs) during COVID-19 pandemic.
    Methods: We searched for publications in MEDLINE, Pubmed and Google Scholar using selected keywords. Each article was reviewed and categorized into one or more of the following three categories based on its subject matter: early diagnosis of COVID-19 in HCWs, detection of worker susceptibility to severe COVID-19, medical examination of HCWs returning to work after COVID-19.
    Results: Selected articles showed the RT-PCR test for Sars-CoV-2 as the gold standard to enable rapid identification of infected HCWs; an effective schedule of occupational health surveillance allows the identification of the susceptibility of the workers to severe Covid-19 and protect HCWs returning to work from the disease.
    Conclusions: The findings of the present narrative review show the need to strenghten the occupational health surveillance of HCWs during the current COVID-19 pandemic, with the aim not only to contain the spread of the infection in healthcare settings, but also to protect HCWs coming back to work after the disease.
    Mesh-Begriff(e) COVID-19 ; Health Personnel ; Humans ; Occupational Health ; Pandemics ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2022-03-14
    Erscheinungsland Italy
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v93i1.10277
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Joining Forces against Antibiotic Resistance: The One Health Solution.

    Cella, Eleonora / Giovanetti, Marta / Benedetti, Francesca / Scarpa, Fabio / Johnston, Catherine / Borsetti, Alessandra / Ceccarelli, Giancarlo / Azarian, Taj / Zella, Davide / Ciccozzi, Massimo

    Pathogens (Basel, Switzerland)

    2023  Band 12, Heft 9

    Abstract: Antibiotic resistance is a significant global health concern that affects both human and animal populations. ... ...

    Abstract Antibiotic resistance is a significant global health concern that affects both human and animal populations. The
    Sprache Englisch
    Erscheinungsdatum 2023-08-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12091074
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  9. Artikel ; Online: SARS-CoV-2 pandemic, influenza, and influenza-like illness epidemics: Allies or enemies?

    Ceccarelli, Giancarlo / d'Ettorre, Gabriele / Russo, Alessandro / Fabris, Silvia / Ciccozzi, Massimo / d'Ettorre, Gabriella

    Journal of medical virology

    2022  Band 95, Heft 1, Seite(n) e28148

    Mesh-Begriff(e) Humans ; SARS-CoV-2 ; Influenza, Human/epidemiology ; Pandemics ; COVID-19/epidemiology ; Virus Diseases ; Epidemics
    Sprache Englisch
    Erscheinungsdatum 2022-09-21
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28148
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  10. Artikel ; Online: Post-traumatic stress disorder symptoms in healthcare workers: a ten-year systematic review.

    D'Ettorre, Gabriele / Pellicani, Vincenza / Ceccarelli, Giancarlo

    Acta bio-medica : Atenei Parmensis

    2020  Band 91, Heft 12-S, Seite(n) e2020009

    Abstract: Background and aims: Healthcare workers (HCWs) employed in hospital settings frequently experience many occupational stressors leading to post-traumatic stress disorder (PTSD) symptoms. Literature has increasingly highlighted PTSD as a major issue that ... ...

    Abstract Background and aims: Healthcare workers (HCWs) employed in hospital settings frequently experience many occupational stressors leading to post-traumatic stress disorder (PTSD) symptoms. Literature has increasingly highlighted PTSD as a major issue that involves both staff and healthcare organizations; the consequences of PTSD may include medication errors and lower standards of care. The current COVID-19 pandemic poses the need for preventing PTSD in HCWs working closely with COVID-19 patients. The purpose of this systematic review was to analyze the latest developments in assessing and managing the occupational risk of PTSD symptoms in hospital HCWs.
    Methods: We searched for publications in MEDLINE/Pubmed using selected keywords. Each article was reviewed and categorized into one or more of the following four categories based on its subject matter: risk assessment, risk management and occurrence rates.
    Results: Our search resulted in a total of 32 publications that matched our inclusion criteria.  Increased years of service, older age, previous year exposure to violence, personality traits (i.e. neuroticism), history of mental disorders, being non-graduates, were found to be workers' pre-trauma factors predicting PTSD symptoms.
    Conclusions: The findings suggest the need to prioritize preventative interventions aimed to anticipate the effects of traumatic exposure by training HCWs in evidence based anticipatory methods of coping with stressful events. With regard to the current COVID-19 pandemic, we found evidence of the need to strength social support and training targeted at psychological skills of medical staff who treated COVID-19 patients.
    Mesh-Begriff(e) Age Factors ; Exposure to Violence ; Health Personnel/psychology ; Humans ; Mental Disorders/complications ; Personality ; Risk Factors ; Stress Disorders, Post-Traumatic/etiology
    Sprache Englisch
    Erscheinungsdatum 2020-11-30
    Erscheinungsland Italy
    Dokumenttyp Journal Article ; Systematic Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v91i12-S.9459
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